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The map label for this gene is ruvC [H]

Identifier: 239617282

GI number: 239617282

Start: 943354

End: 943860

Strand: Reverse

Name: ruvC [H]

Synonym: Kole_0891

Alternate gene names: 239617282

Gene position: 943860-943354 (Counterclockwise)

Preceding gene: 239617283

Following gene: 239617281

Centisome position: 41.0

GC content: 45.36

Gene sequence:

>507_bases
TTGGCAAAGAGTTGTACTCGAATCCTTGGTATCGATCCTGGCTTTGGCACTTTAGGATACGGTTTGATAGATGTTTCTGG
CTCAAAAGTCTCGCTGGTTGGTTACGGTGTTATTCAAACAAAACCGGGTGAGCCGATCCCAAATAGACTGTTGAAGATAT
ACGATCGCCTCCACGAAATTGTGGAAGAGTATCGACCAGATGAAGCTGCTATCGAAGAGCTTTTCTTCTTCAGAAACGTT
ACAACTGCCATTCAGGTTGGAGAAGCGAGAGGGGTTGTTTTGCTGGTTTTGAAGCAGCTTAGTATTCCCATTTTTGAATA
CACACCGCACCAGGTTAAACAATCAGTTACTGGATATGGTCGTTCTGAGAAGGGGCAGATCCAGCGGGTTATGAAAAAGT
TTCTGGGAATGAACGAAACTCCAAAACCTGATGATGCTGCGGATGCTCTGGCAGTTGCATGGTGTCATATCTCCTTTCGA
AGATTTCCCGGAGGTGCTCATAGGTGA

Upstream 100 bases:

>100_bases
GCGTTTGATTCTGTCAAAGCCTCCTTTCCCACGTGAAGAGATTGTTCTATCTCTTTCGCAGATTTTCAGGAAGTAAAATG
GTAAAGCTGGAGGTGTTGTT

Downstream 100 bases:

>100_bases
AGTTACGTTTCAAAGAATTGAATATACCAATCTCCAGGATTGTTGAAAGAATCCTTGGTTTTTATCCGGAGTACAACTGT
GATTCATTTTATGTGCTGGA

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MAKSCTRILGIDPGFGTLGYGLIDVSGSKVSLVGYGVIQTKPGEPIPNRLLKIYDRLHEIVEEYRPDEAAIEELFFFRNV
TTAIQVGEARGVVLLVLKQLSIPIFEYTPHQVKQSVTGYGRSEKGQIQRVMKKFLGMNETPKPDDAADALAVAWCHISFR
RFPGGAHR

Sequences:

>Translated_168_residues
MAKSCTRILGIDPGFGTLGYGLIDVSGSKVSLVGYGVIQTKPGEPIPNRLLKIYDRLHEIVEEYRPDEAAIEELFFFRNV
TTAIQVGEARGVVLLVLKQLSIPIFEYTPHQVKQSVTGYGRSEKGQIQRVMKKFLGMNETPKPDDAADALAVAWCHISFR
RFPGGAHR
>Mature_167_residues
AKSCTRILGIDPGFGTLGYGLIDVSGSKVSLVGYGVIQTKPGEPIPNRLLKIYDRLHEIVEEYRPDEAAIEELFFFRNVT
TAIQVGEARGVVLLVLKQLSIPIFEYTPHQVKQSVTGYGRSEKGQIQRVMKKFLGMNETPKPDDAADALAVAWCHISFRR
FPGGAHR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=152, Percent_Identity=40.1315789473684, Blast_Score=114, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 18646; Mature: 18515

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSCTRILGIDPGFGTLGYGLIDVSGSKVSLVGYGVIQTKPGEPIPNRLLKIYDRLHEI
CCCCCCHHEECCCCCCCCCCEEEECCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
VEEYRPDEAAIEELFFFRNVTTAIQVGEARGVVLLVLKQLSIPIFEYTPHQVKQSVTGYG
HHHHCCCHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCCCCEECCHHHHHHHHHCCC
RSEKGQIQRVMKKFLGMNETPKPDDAADALAVAWCHISFRRFPGGAHR
CCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AKSCTRILGIDPGFGTLGYGLIDVSGSKVSLVGYGVIQTKPGEPIPNRLLKIYDRLHEI
CCCCCHHEECCCCCCCCCCEEEECCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
VEEYRPDEAAIEELFFFRNVTTAIQVGEARGVVLLVLKQLSIPIFEYTPHQVKQSVTGYG
HHHHCCCHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCCCCEECCHHHHHHHHHCCC
RSEKGQIQRVMKKFLGMNETPKPDDAADALAVAWCHISFRRFPGGAHR
CCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA