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The map label for this gene is polC [H]

Identifier: 239617281

GI number: 239617281

Start: 939065

End: 943357

Strand: Reverse

Name: polC [H]

Synonym: Kole_0890

Alternate gene names: 239617281

Gene position: 943357-939065 (Counterclockwise)

Preceding gene: 239617282

Following gene: 239617280

Centisome position: 40.98

GC content: 41.42

Gene sequence:

>4293_bases
GTGAAGTTACGTTTCAAAGAATTGAATATACCAATCTCCAGGATTGTTGAAAGAATCCTTGGTTTTTATCCGGAGTACAA
CTGTGATTCATTTTATGTGCTGGATGCAGTTGTGGACCTCTCAAAGAGAGAAATGACTCTTGTATTCGATGACAAACTTC
CAGAAAAAATCAAAAGATTTCTTCTGGAGCGTTTTGTAAAAGTAGCTTCTGCGCAACTAAACATAAGGGTTTCTCTTGGG
TTCAGACCCGTCAGTGAATCTTTACATCATCCGGATGGAGTTCCTTTGGCTGGCAAAGAGCCCTCCGGAGTAGATGATGC
TGAATTTGACATCGACGCTTTTATTAAACACACGAATGGTCTGGCTTCTTATCTAGAACAGTCGGATATCAAATTTGATG
GTGAGAAAATAATCATACACGTTAAAAATAGTTTTGCAGAAGCGCGTATAAGATCAAAAAAAGATGATTTACGACAGGCG
ATAAAGAAGACTGCAGGGAAAAATATCCCTTTCGAAATAATTTTTGAACCCATACAGAATGAAGCTAAGCCAGATATTGT
GCCCGAAACACCTTTAATACTTTCGCCTTCTTCAGCGACTTCTGGCGAATCAGCACAGGTTTTGAAACCCTCTAAAAAGG
AGAGTACAGTAATTCTCGGGAGAAGAATCAGACAGGCACCACAGAAGATTTGTGATGTTATGGGTAGAGAAAAAGATGTG
GTTGTTGCTGGAAAGGTCTTTGGTCTTGATAAATGGAATGGAAAGGTGTCTGTTCTTACCTTCAATGTAACGGATTTTAC
CGATTCGATAATCTGTAAGTTGATCGGCGCAAAAGCCAGAGAGGTATGGAATGGAATAAATAACGGGGACGAGCTTTTGG
TAAGAGGAAAGCTTGAATATGATGACAGGATAAAAGAAGAAGTTTTAATGGTAAGAGACCTGAACCAGATCGAACTCCCG
AAGCGGAAAGATAATGCCGAGGAGAAACGCGTCGAACTTCACCTCCATACAAAAATGAGTGCACTCGATGCTATTGTCGA
TGTTAACGAATTGTTCAAAACCCTTAAAAGTTGGGGACACGATGCTGTAGCCCTTACGGATCACGGTGTTGTTCAGTCCA
TTCCAAATTTCTACTTTGCCGCGAAAAAAAGCGGGATAAAACCTATCTTTGGAATGGAAGGTTACATGGTAAATGATTCA
GAACCCATCGTAAGGGAAATAGAAGATAAAAACCTTGAGTTGATGAACAGCATTTATGTGGTTTTTGATCTTGAAACCAC
CGGGCTTGATCCTTCAGCAGATGAAATCATTGAAATAGGCGCTGTTAAGCTGAAAGGAACCGAAGTAATAGGAGAATTCT
CATCTTTTGTAAAACCAGAAAGAAATCTTTCTGAAAAAGTTACCAGAATAACAGGGATCAGTGATAGAGAATTGGAAGAT
GCCCCATCGCTTTCTGAAGTACTACCGAAATTTCTCGAGTTTTGTAAAGATTCTGTTCTGGTTGCTCACAACGCAACTTT
CGATTACCGCTTTGTAAGAAACGCGGTCAAGCAGCTGTACAACGAAGACTGGAAATTACCTTATATAGATACTCTGGCTT
TATCCAAAAGCCTTCTCAAATCGAAAAGCTATTCTTTAGACAATGTTGTTAAACGTCTAAAACTCGGAGATTTTGAACAT
CACAGGGCTTCAGAGGATGCGAGAATAACCGCTGAGGTTTTCAAGAAGCTTCTCTCTATGGCGAAGAAGAGAGGAATAAA
GAAGATAGCAGAGCTCGAAAATTTGAGAAAGCACATAAACATCTCGAGCTTGAGACCGCTTCATGTAACCATACTCGCAA
AAAATAAAACGGGTTTGAGAAATCTCTATGAGCTTGTTACGTTGTCACACACAAAATATTTCTATAAGAAGCCTCGAATA
CCGAAGAGCATTCTTCTCGAAAAGCGTGAGGGATTGATCATTGGTTCAGCTTGTATATCTGGAGAACTTTCGAAGGCGTA
TCTTTCCGGAGCAAATGCTGCGGAGCTTGAGGAGATCGCGAAATTTTTTGATTTTATAGAGATTATGCCGCTGGATGTTC
TGGACTACAACGAAGCAGAAGCTCATATAACACGAGAGAATCTCAAAAATATGTACCGCGAGTTCTACAGGATAGGCAAA
AAACTGAACATTCCTGTGGTGATGACCGGAGATGTTCATTTCTTAGAACCAGAGGATGCTATTTACCGTGCCGTACTTGA
AGCTGCACAAGAGTACCAGAATTTTGACAAGCAACCCTCTCTCTATCTTAGAACCACAGAAGAAATGCTTGAAGCTGCAA
AGGAGATTTTTGAAGACGAAGAGATCGCTTACGAAGTTGTTGTAAAGAACAGCAGAAAAATAGCCTTAATGGTTGAGAAT
ATAGCACCTATAAGAGGGAAACTTCATCCACCCATTATCGAAGGAGCGGACGAACAGGTACGGGAACTAACATACAAAAC
GGCCCATGAGATCTATGGAGATCCACTCCCGGAAATCGTTGAAAAGCGTCTTGAAAAAGAGCTTCGTGCTATCATAGGTC
ATGGTTACGCTGTCCTTTACCTTATTGCTCAGAAGATCGTTAGAAAGTCCAACGAAGACGGATATGTTGTTGGTTCCAGA
GGTTCTGTTGGAAGTTCTCTGGTTGCGACGATGCTGGGAATTACCGAAGTGAACCCGTTACCACCTCACTATGTATGTCC
TGCATGTAAACATTCGGAATTCGTTCTGGACGGTTCAGTTGAATCCGGATACGACCTTAAAGACAAAAGCTGTCCCGAAT
GCGGTGCGCTAATGCAAAAAAACGGCCAGAACATTCCTTTCGAAACCTTTTTGGGGTTTGAAGGTGACAAAGTACCAGAT
ATAGATTTAAACTTCTCGGGAGAATATCAGGAAAGAGCTCATGCATACCTTGAAAAGCTTTTTGGTAAAGATCACGTTTT
CAGAGCAGGCACGATAAGCACGCTTGCTGAAAGAACCGCTTATGGGTTTGTAAAAGCCTACATGGAACGTTCCAAAAAGC
AGTTGAGGAGGGCGGAGATAGACCGCCTTGCTTCTGGAATCGTTGGAGTCAGAAAAACCACAGGACAGCATCCTGGCGGT
CTTATGATCGTTCCCAAGGACAGAGATGTGCATGAGTTCACCCCTGTACAGTTTCCAGCAAACGACACGAAATCTCGAAC
AATGACAACACATTTCGCTTACGAAGTGATTCACGATGATCTGGTCAAGATAGATGCGCTGGGACACGATGATCCAACTT
TTATAAGGATGCTCAAAGATATAACAGGTGTCGATCCAACGACTGTTCCCATGGATGATAAAGATACTTTGTCTATATTC
TCTTCGACGAAGGTTTTAGGAATAAATCCTCGTGACTTAGGTACAGATGTGGGAACTCTCGGGATACCCGAGTTTGGTAC
ACAGTTTGTTCGGGGAATGCTCCGGGAGACCCGTCCGAAAACCTTTGGTGAGCTTGTGAGAATATCCGGGCTCTCCCATG
GAACAGATGTTTGGTTGAATAACGCTCGTGATTGGATAGTTTCGAAAAAAGCAACGCTGTCAGATGTCATTGCATGTCGA
GATGACATTATGAATTATCTGATTTCAAAAGGAATAGAGCCGTTAAAAGCATTCAAAATAATGGAAAAGGTGAGAAAAGG
GAAAGGCATAACGGATGAGGAAGTTGAAATGATGCAGGAAGCAGAAGTACCAGAATGGTTTATTGAATCTTGCCGAAGGA
TCAAATATCTTTTCCCGAAGGCTCACGCTGTTGCTTATGTTAGTATGGGTTACAGGGTGGCGTATTTCAAGGTTCATTAT
CCCCTGGCCTTTTATTCAACTTACTTTACAATAAAGGGTGACGAATTCGATGTAGATCTCGCTCTTGGTGATGTAAGTGG
TATAAGAAAGGAAATTACAAATCTCAAAAATAATGCAAACAAGAATGTCAAAGAAAGATCCAAAGAAACGCTTCTTGAGA
TCGTGCTGGAAATGCGCCTTAGAGGTTATTCCTTTCTGCCTGTTGATTTAGAGAAATCAGATGCGAGACGTTTTTTGATA
GAAGGCAACGCCCTCAGAATACCTTTTAACAGGCTAAAAAACCTTGGGTATAAAGTAGCCATTTCGATAATAAAAGAGCG
TGAGAAGAGGCCATTTAGTTCAGTGGAAGATCTTTTGAAAAGGACTTCGATCAACAAAACGCACGTGGAAATACTGAGAA
AGTATGGGGCCTTCAAAGGACTTCCTGAAAAAGAGCAAATAACACTCTTTTAG

Upstream 100 bases:

>100_bases
TGGGAATGAACGAAACTCCAAAACCTGATGATGCTGCGGATGCTCTGGCAGTTGCATGGTGTCATATCTCCTTTCGAAGA
TTTCCCGGAGGTGCTCATAG

Downstream 100 bases:

>100_bases
GGTGAAGATGAATGCAATTCGTTCTGAAAAACGGGGAATACAAAAAAATACTTGAGCTATGTGAAAAATTTGCCGGGACA
GTTGAACCCGGCTTTCGCTT

Product: DNA polymerase III, alpha subunit

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 1430; Mature: 1430

Protein sequence:

>1430_residues
MKLRFKELNIPISRIVERILGFYPEYNCDSFYVLDAVVDLSKREMTLVFDDKLPEKIKRFLLERFVKVASAQLNIRVSLG
FRPVSESLHHPDGVPLAGKEPSGVDDAEFDIDAFIKHTNGLASYLEQSDIKFDGEKIIIHVKNSFAEARIRSKKDDLRQA
IKKTAGKNIPFEIIFEPIQNEAKPDIVPETPLILSPSSATSGESAQVLKPSKKESTVILGRRIRQAPQKICDVMGREKDV
VVAGKVFGLDKWNGKVSVLTFNVTDFTDSIICKLIGAKAREVWNGINNGDELLVRGKLEYDDRIKEEVLMVRDLNQIELP
KRKDNAEEKRVELHLHTKMSALDAIVDVNELFKTLKSWGHDAVALTDHGVVQSIPNFYFAAKKSGIKPIFGMEGYMVNDS
EPIVREIEDKNLELMNSIYVVFDLETTGLDPSADEIIEIGAVKLKGTEVIGEFSSFVKPERNLSEKVTRITGISDRELED
APSLSEVLPKFLEFCKDSVLVAHNATFDYRFVRNAVKQLYNEDWKLPYIDTLALSKSLLKSKSYSLDNVVKRLKLGDFEH
HRASEDARITAEVFKKLLSMAKKRGIKKIAELENLRKHINISSLRPLHVTILAKNKTGLRNLYELVTLSHTKYFYKKPRI
PKSILLEKREGLIIGSACISGELSKAYLSGANAAELEEIAKFFDFIEIMPLDVLDYNEAEAHITRENLKNMYREFYRIGK
KLNIPVVMTGDVHFLEPEDAIYRAVLEAAQEYQNFDKQPSLYLRTTEEMLEAAKEIFEDEEIAYEVVVKNSRKIALMVEN
IAPIRGKLHPPIIEGADEQVRELTYKTAHEIYGDPLPEIVEKRLEKELRAIIGHGYAVLYLIAQKIVRKSNEDGYVVGSR
GSVGSSLVATMLGITEVNPLPPHYVCPACKHSEFVLDGSVESGYDLKDKSCPECGALMQKNGQNIPFETFLGFEGDKVPD
IDLNFSGEYQERAHAYLEKLFGKDHVFRAGTISTLAERTAYGFVKAYMERSKKQLRRAEIDRLASGIVGVRKTTGQHPGG
LMIVPKDRDVHEFTPVQFPANDTKSRTMTTHFAYEVIHDDLVKIDALGHDDPTFIRMLKDITGVDPTTVPMDDKDTLSIF
SSTKVLGINPRDLGTDVGTLGIPEFGTQFVRGMLRETRPKTFGELVRISGLSHGTDVWLNNARDWIVSKKATLSDVIACR
DDIMNYLISKGIEPLKAFKIMEKVRKGKGITDEEVEMMQEAEVPEWFIESCRRIKYLFPKAHAVAYVSMGYRVAYFKVHY
PLAFYSTYFTIKGDEFDVDLALGDVSGIRKEITNLKNNANKNVKERSKETLLEIVLEMRLRGYSFLPVDLEKSDARRFLI
EGNALRIPFNRLKNLGYKVAISIIKEREKRPFSSVEDLLKRTSINKTHVEILRKYGAFKGLPEKEQITLF

Sequences:

>Translated_1430_residues
MKLRFKELNIPISRIVERILGFYPEYNCDSFYVLDAVVDLSKREMTLVFDDKLPEKIKRFLLERFVKVASAQLNIRVSLG
FRPVSESLHHPDGVPLAGKEPSGVDDAEFDIDAFIKHTNGLASYLEQSDIKFDGEKIIIHVKNSFAEARIRSKKDDLRQA
IKKTAGKNIPFEIIFEPIQNEAKPDIVPETPLILSPSSATSGESAQVLKPSKKESTVILGRRIRQAPQKICDVMGREKDV
VVAGKVFGLDKWNGKVSVLTFNVTDFTDSIICKLIGAKAREVWNGINNGDELLVRGKLEYDDRIKEEVLMVRDLNQIELP
KRKDNAEEKRVELHLHTKMSALDAIVDVNELFKTLKSWGHDAVALTDHGVVQSIPNFYFAAKKSGIKPIFGMEGYMVNDS
EPIVREIEDKNLELMNSIYVVFDLETTGLDPSADEIIEIGAVKLKGTEVIGEFSSFVKPERNLSEKVTRITGISDRELED
APSLSEVLPKFLEFCKDSVLVAHNATFDYRFVRNAVKQLYNEDWKLPYIDTLALSKSLLKSKSYSLDNVVKRLKLGDFEH
HRASEDARITAEVFKKLLSMAKKRGIKKIAELENLRKHINISSLRPLHVTILAKNKTGLRNLYELVTLSHTKYFYKKPRI
PKSILLEKREGLIIGSACISGELSKAYLSGANAAELEEIAKFFDFIEIMPLDVLDYNEAEAHITRENLKNMYREFYRIGK
KLNIPVVMTGDVHFLEPEDAIYRAVLEAAQEYQNFDKQPSLYLRTTEEMLEAAKEIFEDEEIAYEVVVKNSRKIALMVEN
IAPIRGKLHPPIIEGADEQVRELTYKTAHEIYGDPLPEIVEKRLEKELRAIIGHGYAVLYLIAQKIVRKSNEDGYVVGSR
GSVGSSLVATMLGITEVNPLPPHYVCPACKHSEFVLDGSVESGYDLKDKSCPECGALMQKNGQNIPFETFLGFEGDKVPD
IDLNFSGEYQERAHAYLEKLFGKDHVFRAGTISTLAERTAYGFVKAYMERSKKQLRRAEIDRLASGIVGVRKTTGQHPGG
LMIVPKDRDVHEFTPVQFPANDTKSRTMTTHFAYEVIHDDLVKIDALGHDDPTFIRMLKDITGVDPTTVPMDDKDTLSIF
SSTKVLGINPRDLGTDVGTLGIPEFGTQFVRGMLRETRPKTFGELVRISGLSHGTDVWLNNARDWIVSKKATLSDVIACR
DDIMNYLISKGIEPLKAFKIMEKVRKGKGITDEEVEMMQEAEVPEWFIESCRRIKYLFPKAHAVAYVSMGYRVAYFKVHY
PLAFYSTYFTIKGDEFDVDLALGDVSGIRKEITNLKNNANKNVKERSKETLLEIVLEMRLRGYSFLPVDLEKSDARRFLI
EGNALRIPFNRLKNLGYKVAISIIKEREKRPFSSVEDLLKRTSINKTHVEILRKYGAFKGLPEKEQITLF
>Mature_1430_residues
MKLRFKELNIPISRIVERILGFYPEYNCDSFYVLDAVVDLSKREMTLVFDDKLPEKIKRFLLERFVKVASAQLNIRVSLG
FRPVSESLHHPDGVPLAGKEPSGVDDAEFDIDAFIKHTNGLASYLEQSDIKFDGEKIIIHVKNSFAEARIRSKKDDLRQA
IKKTAGKNIPFEIIFEPIQNEAKPDIVPETPLILSPSSATSGESAQVLKPSKKESTVILGRRIRQAPQKICDVMGREKDV
VVAGKVFGLDKWNGKVSVLTFNVTDFTDSIICKLIGAKAREVWNGINNGDELLVRGKLEYDDRIKEEVLMVRDLNQIELP
KRKDNAEEKRVELHLHTKMSALDAIVDVNELFKTLKSWGHDAVALTDHGVVQSIPNFYFAAKKSGIKPIFGMEGYMVNDS
EPIVREIEDKNLELMNSIYVVFDLETTGLDPSADEIIEIGAVKLKGTEVIGEFSSFVKPERNLSEKVTRITGISDRELED
APSLSEVLPKFLEFCKDSVLVAHNATFDYRFVRNAVKQLYNEDWKLPYIDTLALSKSLLKSKSYSLDNVVKRLKLGDFEH
HRASEDARITAEVFKKLLSMAKKRGIKKIAELENLRKHINISSLRPLHVTILAKNKTGLRNLYELVTLSHTKYFYKKPRI
PKSILLEKREGLIIGSACISGELSKAYLSGANAAELEEIAKFFDFIEIMPLDVLDYNEAEAHITRENLKNMYREFYRIGK
KLNIPVVMTGDVHFLEPEDAIYRAVLEAAQEYQNFDKQPSLYLRTTEEMLEAAKEIFEDEEIAYEVVVKNSRKIALMVEN
IAPIRGKLHPPIIEGADEQVRELTYKTAHEIYGDPLPEIVEKRLEKELRAIIGHGYAVLYLIAQKIVRKSNEDGYVVGSR
GSVGSSLVATMLGITEVNPLPPHYVCPACKHSEFVLDGSVESGYDLKDKSCPECGALMQKNGQNIPFETFLGFEGDKVPD
IDLNFSGEYQERAHAYLEKLFGKDHVFRAGTISTLAERTAYGFVKAYMERSKKQLRRAEIDRLASGIVGVRKTTGQHPGG
LMIVPKDRDVHEFTPVQFPANDTKSRTMTTHFAYEVIHDDLVKIDALGHDDPTFIRMLKDITGVDPTTVPMDDKDTLSIF
SSTKVLGINPRDLGTDVGTLGIPEFGTQFVRGMLRETRPKTFGELVRISGLSHGTDVWLNNARDWIVSKKATLSDVIACR
DDIMNYLISKGIEPLKAFKIMEKVRKGKGITDEEVEMMQEAEVPEWFIESCRRIKYLFPKAHAVAYVSMGYRVAYFKVHY
PLAFYSTYFTIKGDEFDVDLALGDVSGIRKEITNLKNNANKNVKERSKETLLEIVLEMRLRGYSFLPVDLEKSDARRFLI
EGNALRIPFNRLKNLGYKVAISIIKEREKRPFSSVEDLLKRTSINKTHVEILRKYGAFKGLPEKEQITLF

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2176

COG function: function code L; DNA polymerase III, alpha subunit (gram-positive type)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Escherichia coli, GI1786381, Length=930, Percent_Identity=22.1505376344086, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI1786409, Length=167, Percent_Identity=31.7365269461078, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR023223
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 162060; Mature: 162060

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRFKELNIPISRIVERILGFYPEYNCDSFYVLDAVVDLSKREMTLVFDDKLPEKIKRF
CCCEEHHCCCCHHHHHHHHHHCCCCCCCCCEEHHHHHHHCCCCCEEEEECCCCHHHHHHH
LLERFVKVASAQLNIRVSLGFRPVSESLHHPDGVPLAGKEPSGVDDAEFDIDAFIKHTNG
HHHHHHHHHCCEEEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LASYLEQSDIKFDGEKIIIHVKNSFAEARIRSKKDDLRQAIKKTAGKNIPFEIIFEPIQN
HHHHHHHCCCEECCCEEEEEEECCHHHHHHHCCHHHHHHHHHHHHCCCCCHHEEEEHHCC
EAKPDIVPETPLILSPSSATSGESAQVLKPSKKESTVILGRRIRQAPQKICDVMGREKDV
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCE
VVAGKVFGLDKWNGKVSVLTFNVTDFTDSIICKLIGAKAREVWNGINNGDELLVRGKLEY
EEEEEEEECCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCH
DDRIKEEVLMVRDLNQIELPKRKDNAEEKRVELHLHTKMSALDAIVDVNELFKTLKSWGH
HHHHHHHHHHHHCCCHHCCCCCCCCCCHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
DAVALTDHGVVQSIPNFYFAAKKSGIKPIFGMEGYMVNDSEPIVREIEDKNLELMNSIYV
CEEEEECCHHHHHCCHHHHHHHHCCCCCEECCCCEEECCCCHHHHHHCCCCCEEEEEEEE
VFDLETTGLDPSADEIIEIGAVKLKGTEVIGEFSSFVKPERNLSEKVTRITGISDRELED
EEEEEECCCCCCHHHHHHHCCEEEECHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCC
APSLSEVLPKFLEFCKDSVLVAHNATFDYRFVRNAVKQLYNEDWKLPYIDTLALSKSLLK
CCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
SKSYSLDNVVKRLKLGDFEHHRASEDARITAEVFKKLLSMAKKRGIKKIAELENLRKHIN
HCCCCHHHHHHHHHCCCCHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ISSLRPLHVTILAKNKTGLRNLYELVTLSHTKYFYKKPRIPKSILLEKREGLIIGSACIS
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEHHHHC
GELSKAYLSGANAAELEEIAKFFDFIEIMPLDVLDYNEAEAHITRENLKNMYREFYRIGK
CCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCC
KLNIPVVMTGDVHFLEPEDAIYRAVLEAAQEYQNFDKQPSLYLRTTEEMLEAAKEIFEDE
CCCCCEEEECCEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHCCH
EIAYEVVVKNSRKIALMVENIAPIRGKLHPPIIEGADEQVRELTYKTAHEIYGDPLPEIV
HHEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
EKRLEKELRAIIGHGYAVLYLIAQKIVRKSNEDGYVVGSRGSVGSSLVATMLGITEVNPL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCC
PPHYVCPACKHSEFVLDGSVESGYDLKDKSCPECGALMQKNGQNIPFETFLGFEGDKVPD
CCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHCCCCCCCCCCC
IDLNFSGEYQERAHAYLEKLFGKDHVFRAGTISTLAERTAYGFVKAYMERSKKQLRRAEI
CCCCCCCCHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRLASGIVGVRKTTGQHPGGLMIVPKDRDVHEFTPVQFPANDTKSRTMTTHFAYEVIHDD
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHH
LVKIDALGHDDPTFIRMLKDITGVDPTTVPMDDKDTLSIFSSTKVLGINPRDLGTDVGTL
HHEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCEEEECCCHHHCCCCCCC
GIPEFGTQFVRGMLRETRPKTFGELVRISGLSHGTDVWLNNARDWIVSKKATLSDVIACR
CCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHEECCCHHHHHCCHHHHHHHHHHH
DDIMNYLISKGIEPLKAFKIMEKVRKGKGITDEEVEMMQEAEVPEWFIESCRRIKYLFPK
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
AHAVAYVSMGYRVAYFKVHYPLAFYSTYFTIKGDEFDVDLALGDVSGIRKEITNLKNNAN
HHHEEEEECCEEEEEEEEECCEEEEEEEEEEECCCEEEEEEECHHHHHHHHHHHHHCCCC
KNVKERSKETLLEIVLEMRLRGYSFLPVDLEKSDARRFLIEGNALRIPFNRLKNLGYKVA
CCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEECCEEECCHHHHHCCCHHHH
ISIIKEREKRPFSSVEDLLKRTSINKTHVEILRKYGAFKGLPEKEQITLF
HHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEEC
>Mature Secondary Structure
MKLRFKELNIPISRIVERILGFYPEYNCDSFYVLDAVVDLSKREMTLVFDDKLPEKIKRF
CCCEEHHCCCCHHHHHHHHHHCCCCCCCCCEEHHHHHHHCCCCCEEEEECCCCHHHHHHH
LLERFVKVASAQLNIRVSLGFRPVSESLHHPDGVPLAGKEPSGVDDAEFDIDAFIKHTNG
HHHHHHHHHCCEEEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LASYLEQSDIKFDGEKIIIHVKNSFAEARIRSKKDDLRQAIKKTAGKNIPFEIIFEPIQN
HHHHHHHCCCEECCCEEEEEEECCHHHHHHHCCHHHHHHHHHHHHCCCCCHHEEEEHHCC
EAKPDIVPETPLILSPSSATSGESAQVLKPSKKESTVILGRRIRQAPQKICDVMGREKDV
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCE
VVAGKVFGLDKWNGKVSVLTFNVTDFTDSIICKLIGAKAREVWNGINNGDELLVRGKLEY
EEEEEEEECCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCH
DDRIKEEVLMVRDLNQIELPKRKDNAEEKRVELHLHTKMSALDAIVDVNELFKTLKSWGH
HHHHHHHHHHHHCCCHHCCCCCCCCCCHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
DAVALTDHGVVQSIPNFYFAAKKSGIKPIFGMEGYMVNDSEPIVREIEDKNLELMNSIYV
CEEEEECCHHHHHCCHHHHHHHHCCCCCEECCCCEEECCCCHHHHHHCCCCCEEEEEEEE
VFDLETTGLDPSADEIIEIGAVKLKGTEVIGEFSSFVKPERNLSEKVTRITGISDRELED
EEEEEECCCCCCHHHHHHHCCEEEECHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCC
APSLSEVLPKFLEFCKDSVLVAHNATFDYRFVRNAVKQLYNEDWKLPYIDTLALSKSLLK
CCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
SKSYSLDNVVKRLKLGDFEHHRASEDARITAEVFKKLLSMAKKRGIKKIAELENLRKHIN
HCCCCHHHHHHHHHCCCCHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ISSLRPLHVTILAKNKTGLRNLYELVTLSHTKYFYKKPRIPKSILLEKREGLIIGSACIS
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEHHHHC
GELSKAYLSGANAAELEEIAKFFDFIEIMPLDVLDYNEAEAHITRENLKNMYREFYRIGK
CCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCC
KLNIPVVMTGDVHFLEPEDAIYRAVLEAAQEYQNFDKQPSLYLRTTEEMLEAAKEIFEDE
CCCCCEEEECCEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHCCH
EIAYEVVVKNSRKIALMVENIAPIRGKLHPPIIEGADEQVRELTYKTAHEIYGDPLPEIV
HHEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
EKRLEKELRAIIGHGYAVLYLIAQKIVRKSNEDGYVVGSRGSVGSSLVATMLGITEVNPL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCC
PPHYVCPACKHSEFVLDGSVESGYDLKDKSCPECGALMQKNGQNIPFETFLGFEGDKVPD
CCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHCCCCCCCCCCC
IDLNFSGEYQERAHAYLEKLFGKDHVFRAGTISTLAERTAYGFVKAYMERSKKQLRRAEI
CCCCCCCCHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRLASGIVGVRKTTGQHPGGLMIVPKDRDVHEFTPVQFPANDTKSRTMTTHFAYEVIHDD
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHH
LVKIDALGHDDPTFIRMLKDITGVDPTTVPMDDKDTLSIFSSTKVLGINPRDLGTDVGTL
HHEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCEEEECCCHHHCCCCCCC
GIPEFGTQFVRGMLRETRPKTFGELVRISGLSHGTDVWLNNARDWIVSKKATLSDVIACR
CCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHEECCCHHHHHCCHHHHHHHHHHH
DDIMNYLISKGIEPLKAFKIMEKVRKGKGITDEEVEMMQEAEVPEWFIESCRRIKYLFPK
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
AHAVAYVSMGYRVAYFKVHYPLAFYSTYFTIKGDEFDVDLALGDVSGIRKEITNLKNNAN
HHHEEEEECCEEEEEEEEECCEEEEEEEEEEECCCEEEEEEECHHHHHHHHHHHHHCCCC
KNVKERSKETLLEIVLEMRLRGYSFLPVDLEKSDARRFLIEGNALRIPFNRLKNLGYKVA
CCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEECCEEECCHHHHHCCCHHHH
ISIIKEREKRPFSSVEDLLKRTSINKTHVEILRKYGAFKGLPEKEQITLF
HHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9826752; 10360571 [H]