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The map label for this gene is speH [H]

Identifier: 239616677

GI number: 239616677

Start: 295613

End: 296008

Strand: Direct

Name: speH [H]

Synonym: Kole_0270

Alternate gene names: 239616677

Gene position: 295613-296008 (Clockwise)

Preceding gene: 239616672

Following gene: 239616678

Centisome position: 12.84

GC content: 45.71

Gene sequence:

>396_bases
GTGAAAAAAGTTAAGGCTCTCGGGCGTCACTTGGTGGCTGAGTTCTTTGAATGCTCGTCTGAAGCACTGGACAATCTCGA
CTTCGTAGTCAATTCCATGAGGCAGGCCGCTGAGGAAGCTGGGGCTACGATCGTTGATTCGTCGTTTCACAGATTTTTGC
CACATGGAATAAGTGGAGTTGTTGTAATAGCGGAATCTCATCTTGCAATACATACCTGGCCGGAATACGGGTACGCAGCT
ATAGACCTCTTCACCTGCGGCGATGAGGTTAACCCATGGAAAGCTTTTGAATTCTTGAGGATAAAATTTGATGCAAAAAA
AACCAGCGTGGTTGAACACCTTAGAGGAATTTACTCCGAAATTGGGATTCCTGAAACTGCACCACACAAGGTATAA

Upstream 100 bases:

>100_bases
TCTCTAAAAGAATATAATGCAATCGCATCACATAAAGAGTTAGCACAAATGCCTTACCCGAGAGGGGGGCATAATTTTTG
ATATATGGAGGGAAGAAAAG

Downstream 100 bases:

>100_bases
CGGAGGGGATTGGTGTGAAAAAAGATCTTAGAACGATGGATCATCTTATGTACATGGAATATTATACTGGTAGAAACGCA
GGCATTTTTATGAAGATAAA

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MKKVKALGRHLVAEFFECSSEALDNLDFVVNSMRQAAEEAGATIVDSSFHRFLPHGISGVVVIAESHLAIHTWPEYGYAA
IDLFTCGDEVNPWKAFEFLRIKFDAKKTSVVEHLRGIYSEIGIPETAPHKV

Sequences:

>Translated_131_residues
MKKVKALGRHLVAEFFECSSEALDNLDFVVNSMRQAAEEAGATIVDSSFHRFLPHGISGVVVIAESHLAIHTWPEYGYAA
IDLFTCGDEVNPWKAFEFLRIKFDAKKTSVVEHLRGIYSEIGIPETAPHKV
>Mature_131_residues
MKKVKALGRHLVAEFFECSSEALDNLDFVVNSMRQAAEEAGATIVDSSFHRFLPHGISGVVVIAESHLAIHTWPEYGYAA
IDLFTCGDEVNPWKAFEFLRIKFDAKKTSVVEHLRGIYSEIGIPETAPHKV

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 14603; Mature: 14603

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVKALGRHLVAEFFECSSEALDNLDFVVNSMRQAAEEAGATIVDSSFHRFLPHGISGV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHCCCCCCEE
VVIAESHLAIHTWPEYGYAAIDLFTCGDEVNPWKAFEFLRIKFDAKKTSVVEHLRGIYSE
EEEECCCEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHEEECCHHHHHHHHHHHHHHH
IGIPETAPHKV
CCCCCCCCCCC
>Mature Secondary Structure
MKKVKALGRHLVAEFFECSSEALDNLDFVVNSMRQAAEEAGATIVDSSFHRFLPHGISGV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHCCCCCCEE
VVIAESHLAIHTWPEYGYAAIDLFTCGDEVNPWKAFEFLRIKFDAKKTSVVEHLRGIYSE
EEEECCCEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHEEECCHHHHHHHHHHHHHHH
IGIPETAPHKV
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA