Click here to switch to the map view.

The map label for this gene is dppA [H]

Identifier: 239616672

GI number: 239616672

Start: 290791

End: 291630

Strand: Direct

Name: dppA [H]

Synonym: Kole_0265

Alternate gene names: 239616672

Gene position: 290791-291630 (Clockwise)

Preceding gene: 239616671

Following gene: 239616677

Centisome position: 12.63

GC content: 43.33

Gene sequence:

>840_bases
ATGAAGATATTCATTTCGACAGATATGGAAGGCATTGCGGGGGTAGTCTCCTGGAACGAGATGAAGTCAAACAACAAAAT
ATATACCACCATGCAGAACACGGAACTCAACTGGGTAATTGAACTCATCAAAGAATCAAAATTAAACGAACAGGTCGAAG
AGATAGTGATTTGCGATTCCCATTCCAGGGGAGAAAATCTGCCCTTTGGTGGTATTTCTGACCACAGAGTTAGCTGGATC
AGGGGTTACCCGAGACCTTTTTATATGATGCAAGGGCTTGATAACAGCTTCGACCTTGTTATGCTCCTCGGCTATCATGG
CAAAGTAGGTTCGTTCCGGGCTGGTATGGATCACACCTATGCCGGATCCTGCATCTACAACATAAGACTGAACGGAAAAG
AAGTTGGTGAAACAGAGATAAATGCTTATTACGCAGGAGTCTTCGGTGTACCGGTAGGACTGATTACAGGCGATGATGTT
CTCGAAAAGCAGGTCAAAGAATTCTTTGGAAACGATTTTCCCTTTGTAAGAACGAAAGAAGGAATCGGAAGATTCTCCGC
CAAAGTCTATCATCCAGTCAAGGTAAAAAAAGCATACGAAAAGGCTTTCGAAAAGTTATTGGAGCAGCTCGATAGCCTGG
AAGTCAAGAAACTCAATGGTGAGATAACCCTCGAGGTTGATCTTGTTACAACTGTTGTCGCAGATGCGGTCGCAATTATA
CCGGGGTTAACCAGAACCTCTGGCAGAACAGTTAGATACACATCCACAGAATATCTAGAAATATTCAGGATGATACTGGC
AATAGCAATGCTTGGTGGCCGATTTGCCAATTACGAATAA

Upstream 100 bases:

>100_bases
TGTTCTCATCTCCTTCTTCAAGGAAAGGCAAATAGAAGTAGAGATGAATGGTAACATCGTCTTTGTTGAAAAGGTGTAAA
GGCTATCAGGGGGGATGGCG

Downstream 100 bases:

>100_bases
GTCTCTTGAAGATATGAAAGGAATCGAGGTTAATCAATCAACGAATCCCGTAGTATGCTTCAAAGATCTTTCTTGCTATC
GCGGCGGCTGTTGTTGAACC

Product: peptidase M55 D-aminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKIFISTDMEGIAGVVSWNEMKSNNKIYTTMQNTELNWVIELIKESKLNEQVEEIVICDSHSRGENLPFGGISDHRVSWI
RGYPRPFYMMQGLDNSFDLVMLLGYHGKVGSFRAGMDHTYAGSCIYNIRLNGKEVGETEINAYYAGVFGVPVGLITGDDV
LEKQVKEFFGNDFPFVRTKEGIGRFSAKVYHPVKVKKAYEKAFEKLLEQLDSLEVKKLNGEITLEVDLVTTVVADAVAII
PGLTRTSGRTVRYTSTEYLEIFRMILAIAMLGGRFANYE

Sequences:

>Translated_279_residues
MKIFISTDMEGIAGVVSWNEMKSNNKIYTTMQNTELNWVIELIKESKLNEQVEEIVICDSHSRGENLPFGGISDHRVSWI
RGYPRPFYMMQGLDNSFDLVMLLGYHGKVGSFRAGMDHTYAGSCIYNIRLNGKEVGETEINAYYAGVFGVPVGLITGDDV
LEKQVKEFFGNDFPFVRTKEGIGRFSAKVYHPVKVKKAYEKAFEKLLEQLDSLEVKKLNGEITLEVDLVTTVVADAVAII
PGLTRTSGRTVRYTSTEYLEIFRMILAIAMLGGRFANYE
>Mature_279_residues
MKIFISTDMEGIAGVVSWNEMKSNNKIYTTMQNTELNWVIELIKESKLNEQVEEIVICDSHSRGENLPFGGISDHRVSWI
RGYPRPFYMMQGLDNSFDLVMLLGYHGKVGSFRAGMDHTYAGSCIYNIRLNGKEVGETEINAYYAGVFGVPVGLITGDDV
LEKQVKEFFGNDFPFVRTKEGIGRFSAKVYHPVKVKKAYEKAFEKLLEQLDSLEVKKLNGEITLEVDLVTTVVADAVAII
PGLTRTSGRTVRYTSTEYLEIFRMILAIAMLGGRFANYE

Specific function: Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear [H]

COG id: COG2362

COG function: function code E; D-aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M55 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007035 [H]

Pfam domain/function: PF04951 Peptidase_M55 [H]

EC number: NA

Molecular weight: Translated: 31445; Mature: 31445

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIFISTDMEGIAGVVSWNEMKSNNKIYTTMQNTELNWVIELIKESKLNEQVEEIVICDS
CEEEEECCCCHHHEEEEHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHEEEECC
HSRGENLPFGGISDHRVSWIRGYPRPFYMMQGLDNSFDLVMLLGYHGKVGSFRAGMDHTY
CCCCCCCCCCCCCCCCCHHHHCCCCHHHHCCCCCCCCCEEEEEECCCCCCCEECCCCCCC
AGSCIYNIRLNGKEVGETEINAYYAGVFGVPVGLITGDDVLEKQVKEFFGNDFPFVRTKE
CCCEEEEEEECCCCCCCCCHHEEEEEHHHCCEEEECCCHHHHHHHHHHHCCCCCCEEEHH
GIGRFSAKVYHPVKVKKAYEKAFEKLLEQLDSLEVKKLNGEITLEVDLVTTVVADAVAII
HHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEHHHHHHHHHHHHHH
PGLTRTSGRTVRYTSTEYLEIFRMILAIAMLGGRFANYE
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKIFISTDMEGIAGVVSWNEMKSNNKIYTTMQNTELNWVIELIKESKLNEQVEEIVICDS
CEEEEECCCCHHHEEEEHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHEEEECC
HSRGENLPFGGISDHRVSWIRGYPRPFYMMQGLDNSFDLVMLLGYHGKVGSFRAGMDHTY
CCCCCCCCCCCCCCCCCHHHHCCCCHHHHCCCCCCCCCEEEEEECCCCCCCEECCCCCCC
AGSCIYNIRLNGKEVGETEINAYYAGVFGVPVGLITGDDVLEKQVKEFFGNDFPFVRTKE
CCCEEEEEEECCCCCCCCCHHEEEEEHHHCCEEEECCCHHHHHHHHHHHCCCCCCEEEHH
GIGRFSAKVYHPVKVKKAYEKAFEKLLEQLDSLEVKKLNGEITLEVDLVTTVVADAVAII
HHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEHHHHHHHHHHHHHH
PGLTRTSGRTVRYTSTEYLEIFRMILAIAMLGGRFANYE
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]