| Definition | Kosmotoga olearia TBF 19.5.1, complete genome. |
|---|---|
| Accession | NC_012785 |
| Length | 2,302,126 |
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The map label for this gene is hppA [H]
Identifier: 239616542
GI number: 239616542
Start: 150034
End: 152205
Strand: Direct
Name: hppA [H]
Synonym: Kole_0134
Alternate gene names: 239616542
Gene position: 150034-152205 (Clockwise)
Preceding gene: 239616541
Following gene: 239616543
Centisome position: 6.52
GC content: 48.3
Gene sequence:
>2172_bases ATGAATGCTCTGTATCTCCCACTAACTGCGGGTGTTCTTTCGACCATCTTTGCATTTATCATGCTTGCCCGTACTTTGAA ATTTTCACCCGGTAACAAGACTATGCAAAAATTATCCGGTTACGTTCAAGAAGGTGCATCTGCCTTTCTCTCTGAGGAAG CACGCAAGATATTCCTGGTGGCCGTCTTAATAGCAGCGGCTCTGGGTATAATCTTTCAGTCGTTCAAATACCCAATCGCT CTTCTTTTCGGTGCCCTTGTATCGGAACTCGCCGGCGTAATGGGGATGTACGCCGCGACGAGAGCAAATGCCAGGGTTAC CCAGGGAGCTACAAAAGGATTATCTGAAGCCTTTAAGGTAGCCTTTTCCGGTGGTTCCGTCATGGGGCTCTCTGTTGCGG GATTCTCCCTTACCGGTTTGAGCATAATAATGCTTGTTTTCAAGGATTCTTTCCTCTACAACAACATCACAGAAATATCG CAAGCCTTCGGAAAAATATCTTTCCTTGATCCGGTTATGATAGTAAGCTCTTACTCTCTTGGTGCGAGTCTCATTGCCCT GTTCGACAGGGTCGGAGGCGGTATGTACACAAAGGCGGCCGACATGAGTGCTGACCTTGTCGGAAAGGTGGAAGCGGGAA TCCCCGAAGACGACCCGAGAAACCCCGCTACTATTGCCGACAACGTCGGAGACAACGTTGGAGACGTGGCCGGGCTCGGT GCGGATATTCTCGAATCCTATGTCGCTTCTGTTGTTTCTGCCATCGTGCTTGCCATCTTCATGAAACTCGCAGACAAACA AATGATCAATGGGCAGGTCCAATACGGGATGAGCCCTGAACAATATTACGGATTGATCCTGCTTCCAATCCTCATCGCCG GCGTTGGTGTCCTTTCTTCGCTCGTTGGAGTGCTGGTTGTGGCAAACATGAAGGCGAAGGATGCCAGAAAAGCCCTCGGT TTTGGTAACGTATTCACCGGTATTCTTGTCCTCGCATCAACCGCTATCGTGATCGGAATCGCCGCACCAGATTACGCATT CAAAGATACCTTTATTCTCAACCCTGAATTCGTTTCCAGATGGAGATTGTTCTTAGCAATCGCCAGCGGTCTGATCGCCG GGTTGATAATAAGCAAATTAAGTGAGTACTACACCTCCTACGACTACAAACCTACACAGGATCTCGCCGAAAAAACAAAA AGCGGTGTTGCAATAAACATAACCTCTGGATTGGCGCTAGGTATGGGAAGCACGTTCTGGCCAGTAATTGTCCTGGCTAT CGCCATTCTCGGTGCCTACTGGTCAGCGGGTGTCTATGGAATAGCAATAGCGGCCCTTGGAATGCTTTCATTCGTTGGAT ACATTGTCAGCGTTGATAGCTATGGTCCTGTTGCTGACAACGCCGGTGGAATCGCCCAGATGGCTGAACTTGATCCAAAG GTTCGTGAGATAACGGATAGACTTGATTCTGTCGGAAATACAACCGCTGCGATCGGTAAAGGATTCGCGATCGGTTCAGC AGCTTTCGCGGCTCTTGCGCTCATAGTTTCTTATATATGGAGTGCCGCACATTCTGCGGAGGAAATCGTAAACAATCCTG TAATTAATCTTGTTTCCCCCTACACAATCATTGGTTCGATCATAGGCGCAATGTTGCCTTTCTTCTTCACCTCACTGTTG ATCCGTGGTGTCGCCGATACAGCAGATCTCATGATAACCGAAATCAGGCGACAGTTCAGAGAACATAAAGGAATTCTGAC AGGCGAAGAAACACCTGATTATAAGAGATGTATAGAAATCACCACAAAGGGTGCGGTCAGCAGAATGCTGCTGCCCGGTA TAATCGCAATCGCGACACCTTTTGTTGTCGGATTCCTCTTTGGTAAGGCAGCGGTTGCCGGATTGCTTCTTGGAGGCCTC GGCAGTGCCATCATGATTGCACTGTTCACAGCGAATTCAGGTGGTGCATGGGATAACGCTAAAAAATACATTGAATCCGG GCATTTCGGTGGAAAAGGAACGGATGTTCACTCCGCTGCGGTTGTTGGGGATACCGTCGGGGATCCTCTGAAAGATACCG TAGGTCCATCAATGGATATTCTGATAAAGCTCATGTCTGTCGTTTCTCTCGTTTTTGGTTCATTATTCCCGGATAAACCG TTCTTTATGTGA
Upstream 100 bases:
>100_bases CTTTCTTACAAAGATCCCGGAGGATGTGGCTGAAAGATGGGACGTTGGGTGGAATATTTAATACCATATTTCTCTTGATT CCTATGAAGGAGGGGAAAAA
Downstream 100 bases:
>100_bases TTACACATATAAAACACCGGGGCAAAACTTGCCCCGGTGTTTTGCTCTAACATAAATGATATGGTATCATTTTATTCCAA AAACAATTGTTCCATCGGAG
Product: membrane-bound proton-translocating pyrophosphatase
Products: NA
Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase; Tm-PPase [H]
Number of amino acids: Translated: 723; Mature: 723
Protein sequence:
>723_residues MNALYLPLTAGVLSTIFAFIMLARTLKFSPGNKTMQKLSGYVQEGASAFLSEEARKIFLVAVLIAAALGIIFQSFKYPIA LLFGALVSELAGVMGMYAATRANARVTQGATKGLSEAFKVAFSGGSVMGLSVAGFSLTGLSIIMLVFKDSFLYNNITEIS QAFGKISFLDPVMIVSSYSLGASLIALFDRVGGGMYTKAADMSADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAGLG ADILESYVASVVSAIVLAIFMKLADKQMINGQVQYGMSPEQYYGLILLPILIAGVGVLSSLVGVLVVANMKAKDARKALG FGNVFTGILVLASTAIVIGIAAPDYAFKDTFILNPEFVSRWRLFLAIASGLIAGLIISKLSEYYTSYDYKPTQDLAEKTK SGVAINITSGLALGMGSTFWPVIVLAIAILGAYWSAGVYGIAIAALGMLSFVGYIVSVDSYGPVADNAGGIAQMAELDPK VREITDRLDSVGNTTAAIGKGFAIGSAAFAALALIVSYIWSAAHSAEEIVNNPVINLVSPYTIIGSIIGAMLPFFFTSLL IRGVADTADLMITEIRRQFREHKGILTGEETPDYKRCIEITTKGAVSRMLLPGIIAIATPFVVGFLFGKAAVAGLLLGGL GSAIMIALFTANSGGAWDNAKKYIESGHFGGKGTDVHSAAVVGDTVGDPLKDTVGPSMDILIKLMSVVSLVFGSLFPDKP FFM
Sequences:
>Translated_723_residues MNALYLPLTAGVLSTIFAFIMLARTLKFSPGNKTMQKLSGYVQEGASAFLSEEARKIFLVAVLIAAALGIIFQSFKYPIA LLFGALVSELAGVMGMYAATRANARVTQGATKGLSEAFKVAFSGGSVMGLSVAGFSLTGLSIIMLVFKDSFLYNNITEIS QAFGKISFLDPVMIVSSYSLGASLIALFDRVGGGMYTKAADMSADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAGLG ADILESYVASVVSAIVLAIFMKLADKQMINGQVQYGMSPEQYYGLILLPILIAGVGVLSSLVGVLVVANMKAKDARKALG FGNVFTGILVLASTAIVIGIAAPDYAFKDTFILNPEFVSRWRLFLAIASGLIAGLIISKLSEYYTSYDYKPTQDLAEKTK SGVAINITSGLALGMGSTFWPVIVLAIAILGAYWSAGVYGIAIAALGMLSFVGYIVSVDSYGPVADNAGGIAQMAELDPK VREITDRLDSVGNTTAAIGKGFAIGSAAFAALALIVSYIWSAAHSAEEIVNNPVINLVSPYTIIGSIIGAMLPFFFTSLL IRGVADTADLMITEIRRQFREHKGILTGEETPDYKRCIEITTKGAVSRMLLPGIIAIATPFVVGFLFGKAAVAGLLLGGL GSAIMIALFTANSGGAWDNAKKYIESGHFGGKGTDVHSAAVVGDTVGDPLKDTVGPSMDILIKLMSVVSLVFGSLFPDKP FFM >Mature_723_residues MNALYLPLTAGVLSTIFAFIMLARTLKFSPGNKTMQKLSGYVQEGASAFLSEEARKIFLVAVLIAAALGIIFQSFKYPIA LLFGALVSELAGVMGMYAATRANARVTQGATKGLSEAFKVAFSGGSVMGLSVAGFSLTGLSIIMLVFKDSFLYNNITEIS QAFGKISFLDPVMIVSSYSLGASLIALFDRVGGGMYTKAADMSADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAGLG ADILESYVASVVSAIVLAIFMKLADKQMINGQVQYGMSPEQYYGLILLPILIAGVGVLSSLVGVLVVANMKAKDARKALG FGNVFTGILVLASTAIVIGIAAPDYAFKDTFILNPEFVSRWRLFLAIASGLIAGLIISKLSEYYTSYDYKPTQDLAEKTK SGVAINITSGLALGMGSTFWPVIVLAIAILGAYWSAGVYGIAIAALGMLSFVGYIVSVDSYGPVADNAGGIAQMAELDPK VREITDRLDSVGNTTAAIGKGFAIGSAAFAALALIVSYIWSAAHSAEEIVNNPVINLVSPYTIIGSIIGAMLPFFFTSLL IRGVADTADLMITEIRRQFREHKGILTGEETPDYKRCIEITTKGAVSRMLLPGIIAIATPFVVGFLFGKAAVAGLLLGGL GSAIMIALFTANSGGAWDNAKKYIESGHFGGKGTDVHSAAVVGDTVGDPLKDTVGPSMDILIKLMSVVSLVFGSLFPDKP FFM
Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane [H]
COG id: COG3808
COG function: function code C; Inorganic pyrophosphatase
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004131 [H]
Pfam domain/function: PF03030 H_PPase [H]
EC number: =3.6.1.1 [H]
Molecular weight: Translated: 75818; Mature: 75818
Theoretical pI: Translated: 5.57; Mature: 5.57
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNALYLPLTAGVLSTIFAFIMLARTLKFSPGNKTMQKLSGYVQEGASAFLSEEARKIFLV CCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH AVLIAAALGIIFQSFKYPIALLFGALVSELAGVMGMYAATRANARVTQGATKGLSEAFKV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH AFSGGSVMGLSVAGFSLTGLSIIMLVFKDSFLYNNITEISQAFGKISFLDPVMIVSSYSL HCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHCCHHHHHHHHHH GASLIALFDRVGGGMYTKAADMSADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAGLG HHHHHHHHHHHCCCCEEHHHCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCHHHHHHCC ADILESYVASVVSAIVLAIFMKLADKQMINGQVQYGMSPEQYYGLILLPILIAGVGVLSS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH LVGVLVVANMKAKDARKALGFGNVFTGILVLASTAIVIGIAAPDYAFKDTFILNPEFVSR HHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCCCCCCEEEECHHHHHH WRLFLAIASGLIAGLIISKLSEYYTSYDYKPTQDLAEKTKSGVAINITSGLALGMGSTFW HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCEEEEECCCHHHCCCCHHH PVIVLAIAILGAYWSAGVYGIAIAALGMLSFVGYIVSVDSYGPVADNAGGIAQMAELDPK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCHH VREITDRLDSVGNTTAAIGKGFAIGSAAFAALALIVSYIWSAAHSAEEIVNNPVINLVSP HHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH YTIIGSIIGAMLPFFFTSLLIRGVADTADLMITEIRRQFREHKGILTGEETPDYKRCIEI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH TTKGAVSRMLLPGIIAIATPFVVGFLFGKAAVAGLLLGGLGSAIMIALFTANSGGAWDNA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHH KKYIESGHFGGKGTDVHSAAVVGDTVGDPLKDTVGPSMDILIKLMSVVSLVFGSLFPDKP HHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC FFM CCC >Mature Secondary Structure MNALYLPLTAGVLSTIFAFIMLARTLKFSPGNKTMQKLSGYVQEGASAFLSEEARKIFLV CCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH AVLIAAALGIIFQSFKYPIALLFGALVSELAGVMGMYAATRANARVTQGATKGLSEAFKV HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH AFSGGSVMGLSVAGFSLTGLSIIMLVFKDSFLYNNITEISQAFGKISFLDPVMIVSSYSL HCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHCCHHHHHHHHHH GASLIALFDRVGGGMYTKAADMSADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAGLG HHHHHHHHHHHCCCCEEHHHCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCHHHHHHCC ADILESYVASVVSAIVLAIFMKLADKQMINGQVQYGMSPEQYYGLILLPILIAGVGVLSS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH LVGVLVVANMKAKDARKALGFGNVFTGILVLASTAIVIGIAAPDYAFKDTFILNPEFVSR HHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCCCCCCCCEEEECHHHHHH WRLFLAIASGLIAGLIISKLSEYYTSYDYKPTQDLAEKTKSGVAINITSGLALGMGSTFW HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCEEEEECCCHHHCCCCHHH PVIVLAIAILGAYWSAGVYGIAIAALGMLSFVGYIVSVDSYGPVADNAGGIAQMAELDPK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCHH VREITDRLDSVGNTTAAIGKGFAIGSAAFAALALIVSYIWSAAHSAEEIVNNPVINLVSP HHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH YTIIGSIIGAMLPFFFTSLLIRGVADTADLMITEIRRQFREHKGILTGEETPDYKRCIEI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH TTKGAVSRMLLPGIIAIATPFVVGFLFGKAAVAGLLLGGLGSAIMIALFTANSGGAWDNA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHH KKYIESGHFGGKGTDVHSAAVVGDTVGDPLKDTVGPSMDILIKLMSVVSLVFGSLFPDKP HHHHHCCCCCCCCCCCHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC FFM CCC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10360571; 9440516; 11343697 [H]