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The map label for this gene is trpD

Identifier: 238925323

GI number: 238925323

Start: 2860947

End: 2861963

Strand: Reverse

Name: trpD

Synonym: EUBREC_2978

Alternate gene names: 238925323

Gene position: 2861963-2860947 (Counterclockwise)

Preceding gene: 238925324

Following gene: 238925322

Centisome position: 82.96

GC content: 46.31

Gene sequence:

>1017_bases
ATGATCAAAGAAGCCATAGTAAAAATCGTAAACAAAGAAGACCTCACATATGATGAGGCATATGCAGTGATGAATGAGAT
CATGGGCGGTGAGACAACATCAACCCAGAATGCAGCGTTTCTTGCAGCTCTTTCAACAAAGAGTGCAAAGGCTGAGACAA
CAGACGAAATCGCAGGCTGTGCAGCGGCCATGAGAGAGCATGCGGTACAGGTGAAAACAGGTATGGATGTGTTCGAAATC
GTAGGAACAGGCGGAGACAATGCACAGAGCTTCAACATTTCAACAACCTCAGCACTTGTTGCAGCAGCAGGCGGCATGAA
GGTGGCAAAGCACGGAAACAGGGCAGCCTCTTCATTATGCGGCACAGCAGACTGCCTTGAGGCGCTCGGTGTCAACATAG
ACCAGAGCCCTGAGAAATGTGTAGAGCTTTTAAATAAAGTCGGCATGTGCTTCTTCTTTGCACAGAAATATCACACATCA
ATGAAATATGTCGGACCTATCAGAAAAGAGCTTGGTTTTAGAACCGTATTCAATATTTTAGGACCGCTCACAAATCCGGG
TTCACCGGCCATGCAGCTTCTCGGAGTGTATGATGAGTACCTTGTAGAGCCGCTTGCACAGGTGCTTGTAAGCCTCGGAG
TAAAGCGTGGAATGGTAGTATATGGCATGGATAAGCTCGATGAGATTTCCATGAGCGCATCGACCAAGATATGCGAGATA
AAGGACGGATGGTTCAGAACCACAGTAATTTCACCGGAGGATTTCGGCTTTGAGCGCTGTACAAAGGAGGATTTAAAAGG
CGGTACACCTGAGGAAAATGCGAAAATTGTACGTGATATCTTAGGCGGACAGAAGGGACATAAGAGAAATGCAGTACTCA
TGAACGCAGGCGCATCACTTTATATAGGAGGAAAGGCCGACAGCATGAAAGAGGGTATCGAGCTAGCAGCTGAAATCATT
GATTCAGGAAAAGCACTTGAAACACTCGATAAGCTCATTGATGTAAGCAACAGCTAA

Upstream 100 bases:

>100_bases
TGAATTTATATATTAGTTGTTGAATTGAAAACAAATAGCAGAACAAAATCATAAACAAAATTATAAACGAAATATCATCG
GAATACAGGAGGACATAATC

Downstream 100 bases:

>100_bases
GCACACAAAACAGGAAAGGAAAAGCGATGAATATTTTAGATCAGCTAGCAGAATATTCAAGGCTTCGCGTGGCAGAGGAC
AAGAAAAAAATAAGCCTTGA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MIKEAIVKIVNKEDLTYDEAYAVMNEIMGGETTSTQNAAFLAALSTKSAKAETTDEIAGCAAAMREHAVQVKTGMDVFEI
VGTGGDNAQSFNISTTSALVAAAGGMKVAKHGNRAASSLCGTADCLEALGVNIDQSPEKCVELLNKVGMCFFFAQKYHTS
MKYVGPIRKELGFRTVFNILGPLTNPGSPAMQLLGVYDEYLVEPLAQVLVSLGVKRGMVVYGMDKLDEISMSASTKICEI
KDGWFRTTVISPEDFGFERCTKEDLKGGTPEENAKIVRDILGGQKGHKRNAVLMNAGASLYIGGKADSMKEGIELAAEII
DSGKALETLDKLIDVSNS

Sequences:

>Translated_338_residues
MIKEAIVKIVNKEDLTYDEAYAVMNEIMGGETTSTQNAAFLAALSTKSAKAETTDEIAGCAAAMREHAVQVKTGMDVFEI
VGTGGDNAQSFNISTTSALVAAAGGMKVAKHGNRAASSLCGTADCLEALGVNIDQSPEKCVELLNKVGMCFFFAQKYHTS
MKYVGPIRKELGFRTVFNILGPLTNPGSPAMQLLGVYDEYLVEPLAQVLVSLGVKRGMVVYGMDKLDEISMSASTKICEI
KDGWFRTTVISPEDFGFERCTKEDLKGGTPEENAKIVRDILGGQKGHKRNAVLMNAGASLYIGGKADSMKEGIELAAEII
DSGKALETLDKLIDVSNS
>Mature_338_residues
MIKEAIVKIVNKEDLTYDEAYAVMNEIMGGETTSTQNAAFLAALSTKSAKAETTDEIAGCAAAMREHAVQVKTGMDVFEI
VGTGGDNAQSFNISTTSALVAAAGGMKVAKHGNRAASSLCGTADCLEALGVNIDQSPEKCVELLNKVGMCFFFAQKYHTS
MKYVGPIRKELGFRTVFNILGPLTNPGSPAMQLLGVYDEYLVEPLAQVLVSLGVKRGMVVYGMDKLDEISMSASTKICEI
KDGWFRTTVISPEDFGFERCTKEDLKGGTPEENAKIVRDILGGQKGHKRNAVLMNAGASLYIGGKADSMKEGIELAAEII
DSGKALETLDKLIDVSNS

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=284, Percent_Identity=41.9014084507042, Blast_Score=224, Evalue=9e-60,
Organism=Saccharomyces cerevisiae, GI6320561, Length=360, Percent_Identity=30.5555555555556, Blast_Score=132, Evalue=5e-32,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_EUBR3 (C4ZI69)

Other databases:

- EMBL:   CP001107
- RefSeq:   YP_002938840.1
- GeneID:   7966679
- GenomeReviews:   CP001107_GR
- KEGG:   ere:EUBREC_2978
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36106; Mature: 36106

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKEAIVKIVNKEDLTYDEAYAVMNEIMGGETTSTQNAAFLAALSTKSAKAETTDEIAGC
CCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHEEEECCCCCCCCCCHHHHHHH
AAAMREHAVQVKTGMDVFEIVGTGGDNAQSFNISTTSALVAAAGGMKVAKHGNRAASSLC
HHHHHHHHHHHHCCCCEEHHCCCCCCCCEEECCCHHHHHHHHCCCCHHHHCCCHHHHHHC
GTADCLEALGVNIDQSPEKCVELLNKVGMCFFFAQKYHTSMKYVGPIRKELGFRTVFNIL
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GPLTNPGSPAMQLLGVYDEYLVEPLAQVLVSLGVKRGMVVYGMDKLDEISMSASTKICEI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHCCCCEEEE
KDGWFRTTVISPEDFGFERCTKEDLKGGTPEENAKIVRDILGGQKGHKRNAVLMNAGASL
CCCEEEEEEECCCCCCHHHHCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCEE
YIGGKADSMKEGIELAAEIIDSGKALETLDKLIDVSNS
EECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIKEAIVKIVNKEDLTYDEAYAVMNEIMGGETTSTQNAAFLAALSTKSAKAETTDEIAGC
CCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHEEEECCCCCCCCCCHHHHHHH
AAAMREHAVQVKTGMDVFEIVGTGGDNAQSFNISTTSALVAAAGGMKVAKHGNRAASSLC
HHHHHHHHHHHHCCCCEEHHCCCCCCCCEEECCCHHHHHHHHCCCCHHHHCCCHHHHHHC
GTADCLEALGVNIDQSPEKCVELLNKVGMCFFFAQKYHTSMKYVGPIRKELGFRTVFNIL
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GPLTNPGSPAMQLLGVYDEYLVEPLAQVLVSLGVKRGMVVYGMDKLDEISMSASTKICEI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHCCCCEEEE
KDGWFRTTVISPEDFGFERCTKEDLKGGTPEENAKIVRDILGGQKGHKRNAVLMNAGASL
CCCEEEEEEECCCCCCHHHHCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEECCCEE
YIGGKADSMKEGIELAAEIIDSGKALETLDKLIDVSNS
EECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA