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The map label for this gene is trpGD [H]

Identifier: 238925324

GI number: 238925324

Start: 2862084

End: 2862650

Strand: Reverse

Name: trpGD [H]

Synonym: EUBREC_2979

Alternate gene names: 238925324

Gene position: 2862650-2862084 (Counterclockwise)

Preceding gene: 238925325

Following gene: 238925323

Centisome position: 82.98

GC content: 45.68

Gene sequence:

>567_bases
ATGATTTTACTGATTGATAACTACGACAGCTTTTCCTACAATCTGTATCAGCTAATCGGCGAGATAGAGCCTGATATCAG
AGTAATCAGAAATGATGAGATGACAGTTGAAGAGATTAGGGCTTTAAAGCCTGATCGCATCATATTATCACCGGGACCGG
GAAGGCCTGAGGATGCGGGCGTGATAATAGCTGTGGCAAAGGAGCTTGGAAAGGAAATCCCAATCCTTGGTGTGTGCCTC
GGACATCAGGCGATATGCGCAGCATATGGTGCGACAGTCACATATGCAAAGGAGCTCATGCACGGAAAGCAATCGGATGT
ATCGTTTGACACAGAAAGCCTTTTATTCAAGGGTTGCCCGAAAAAAGCAAAGGTAGCACGTTACCATTCACTTGCTGCAG
ATGCGGACACGATGCCTGATTGCCTAAAGATTACAGCCACTACAGATGATGGTGAGATCATGGCTGTTGAGCACAAGGAA
TATCCGATATACGGAGTGCAGTTTCACCCGGAGTCAATCATGACACCGGACGGAAAGCAGATGCTTAGTAATTTTATCAA
AGCTTAA

Upstream 100 bases:

>100_bases
GAATAGTTGCGGATTCAGATCCTGAGAAGGAATTTCAGGAGTGCATAAACAAGGCAAAGGCTTCTCTTAAGGCACTGGAA
GTCTCACAGGAGGTGGAAGA

Downstream 100 bases:

>100_bases
TTGAAAATTGCAGCGTTTAATGAATTTATATATTAGTTGTTGAATTGAAAACAAATAGCAGAACAAAATCATAAACAAAA
TTATAAACGAAATATCATCG

Product: anthranilate/para-aminobenzoate synthase component II, TrpG

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MILLIDNYDSFSYNLYQLIGEIEPDIRVIRNDEMTVEEIRALKPDRIILSPGPGRPEDAGVIIAVAKELGKEIPILGVCL
GHQAICAAYGATVTYAKELMHGKQSDVSFDTESLLFKGCPKKAKVARYHSLAADADTMPDCLKITATTDDGEIMAVEHKE
YPIYGVQFHPESIMTPDGKQMLSNFIKA

Sequences:

>Translated_188_residues
MILLIDNYDSFSYNLYQLIGEIEPDIRVIRNDEMTVEEIRALKPDRIILSPGPGRPEDAGVIIAVAKELGKEIPILGVCL
GHQAICAAYGATVTYAKELMHGKQSDVSFDTESLLFKGCPKKAKVARYHSLAADADTMPDCLKITATTDDGEIMAVEHKE
YPIYGVQFHPESIMTPDGKQMLSNFIKA
>Mature_188_residues
MILLIDNYDSFSYNLYQLIGEIEPDIRVIRNDEMTVEEIRALKPDRIILSPGPGRPEDAGVIIAVAKELGKEIPILGVCL
GHQAICAAYGATVTYAKELMHGKQSDVSFDTESLLFKGCPKKAKVARYHSLAADADTMPDCLKITATTDDGEIMAVEHKE
YPIYGVQFHPESIMTPDGKQMLSNFIKA

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=143, Percent_Identity=33.5664335664336, Blast_Score=67, Evalue=9e-12,
Organism=Escherichia coli, GI1789760, Length=186, Percent_Identity=47.3118279569892, Blast_Score=198, Evalue=2e-52,
Organism=Escherichia coli, GI1787517, Length=184, Percent_Identity=40.2173913043478, Blast_Score=134, Evalue=3e-33,
Organism=Escherichia coli, GI1786215, Length=158, Percent_Identity=30.379746835443, Blast_Score=75, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322638, Length=187, Percent_Identity=44.9197860962567, Blast_Score=183, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6324361, Length=209, Percent_Identity=35.4066985645933, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323873, Length=144, Percent_Identity=31.9444444444444, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281365319, Length=115, Percent_Identity=34.7826086956522, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 20746; Mature: 20746

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLIDNYDSFSYNLYQLIGEIEPDIRVIRNDEMTVEEIRALKPDRIILSPGPGRPEDAG
CEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCCCEEEECCCCCCCCCCC
VIIAVAKELGKEIPILGVCLGHQAICAAYGATVTYAKELMHGKQSDVSFDTESLLFKGCP
EEEEEEHHHCCCCCEEEEECCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCC
KKAKVARYHSLAADADTMPDCLKITATTDDGEIMAVEHKEYPIYGVQFHPESIMTPDGKQ
CHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEECCCCCEEEEEECCCCCCCCCHHH
MLSNFIKA
HHHHHHCC
>Mature Secondary Structure
MILLIDNYDSFSYNLYQLIGEIEPDIRVIRNDEMTVEEIRALKPDRIILSPGPGRPEDAG
CEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCCCEEEECCCCCCCCCCC
VIIAVAKELGKEIPILGVCLGHQAICAAYGATVTYAKELMHGKQSDVSFDTESLLFKGCP
EEEEEEHHHCCCCCEEEEECCHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCC
KKAKVARYHSLAADADTMPDCLKITATTDDGEIMAVEHKEYPIYGVQFHPESIMTPDGKQ
CHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEECCCCCEEEEEECCCCCCCCCHHH
MLSNFIKA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685830; 10360571; 7556082 [H]