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The map label for this gene is uidA [H]

Identifier: 238922354

GI number: 238922354

Start: 561615

End: 563450

Strand: Reverse

Name: uidA [H]

Synonym: EUBELI_20590

Alternate gene names: 238922354

Gene position: 563450-561615 (Counterclockwise)

Preceding gene: 238922355

Following gene: 238922353

Centisome position: 89.9

GC content: 36.66

Gene sequence:

>1836_bases
ATGTTATATCCAGTTTTAACACAGTCAAGATTATTAAGCGATTTAAGCGGAGTTTGGGATTTTAAGTTAGATAATGGAAA
AGGTTTTGAAGAAAAATGGTATGAGAAACCTTTGAAAGATGCGGATACAATGCCTGTGCCAGCTTCTTATAATGATCTTA
AGGAGGGAACAGATTTCAGGGATCATTATGGATGGGTATTTTATCAGAGAAATATATCAGTTCCAGAATATGTAAAGAGC
CAGAGAATTGTATTACGTTGTGCGGCAGTTACACATTATGCCATGATATATCTCAATGGCAAACTGATATGTGAGCATAA
AGGAGGATTTCTTCCATTTGAAGTAGAATTAAATGATGATTTACAGGATGGTGATAATCTCCTTACCATTGCGGTTAATA
ATGTTATTGATTACACAACTCTGCCAGTTGGTGGTAAGGCTAACATGATGAGTGGAATGATGGGTGGCATGGGTGCAGGT
GCATCTGACAAACCACAGAACAATCCTAATTTTGATTTCTTTAATTATTGTGGAATTACAAGACCTGTAAAAATCTATAC
TACACCTGAGACATATATCAATGATATTACAGTTACAGCTGATATTGATTTCACAAAAGAAGAACCATCGGCAGTACTTA
ATTACAATGTTGAAATTAAAGGAAAAGATTACAACAACATAACATGTAAAGTTGAATTATTTGATGAAGAAGGCACAAAG
CTTTCAGAAACAGAAGGCTCAGAAGGCACATTTGAGATAAGTAATGTAAGATTATGGCAGCCATTAAATGCTTATCTTTA
TAAGATAAAGGTAACAGCAGGACAGGATGTGTATACACTTCCATATGGTGTAAGAAGTGTAAGAGTAGATGGTACAAAGT
TTTTAATTAATGAAAAGCCATTTTATTTTAAAGGCTACGGAAAGCACGAAGATACATTTCCTAATGGCCGTGGAATAAAT
CTGCCTATGAATACAAAGGATATATCAATTATGAAGTGGCAGCATGCTAACAGCTTCAGAACAAGTCATTATCCTTATAG
CGAGGAGATGATGAGACTTTGTGATGAAGAAGGTATTGTTGTTATTGATGAAACAACAGCAGTAGGAGTCAATCTTCAGT
TCGGTGGAGGAGCTAATTTTGGTGGAGAGAGAATAGGAACATTTGATAAGGAGCATGGAGTGCAGACACAGGAACACCAT
AAGGACGTTATCCGTGATTTGATATCAAGAGATAAGAACCATGCATGTGTTGTTATGTGGAGCATAGCTAATGAACCTGA
TTCAGCAGCAGAAGGTGCATATGACTATTTTAAGCCTTTATATGATCTTGCAAGAGAATTAGATCCTCAGAAACGACCAT
GTACATTAGTAAGTGTTCAGGGAACAACTGCTGATACAGACTGCTCATCTCAATTAAGTGATGTAATCTGTCTTAACAGA
TATTATGGATGGTATTTTGGTGGTCCTGATCTTGAGGTGTCAGAGATTGGACTTCGTAAAGAACTTTCAGACTGGGGTAA
ACTTGGAAAGCCTGTTATGTTCACAGAATATGGAGCTGATACAGTGAGCGGACTCCATGATACAACATCTGTAATGTATA
CAGAAGAATATCAGGTAGAATATTATGAGATGAATAATAAAGTATTTGATGAATTCGACTTTGTTGTAGGTGAACAGGCA
TGGAACTTCGCAGACTTTGCAACAAGCCAGAGCCTGTTAAGAGTACAAGGCAATAAGAAGGGACTGTTTACAAGAGACAG
AAAACCAAAGATGGTTGCACACTACTTCCGTAACAGATGGAGCACAATTCCTGAATTTGGTTATAAGACCAAATAA

Upstream 100 bases:

>100_bases
AAAAAGAGAGTAGAAGCAAATGCAGCTAAGTTAAAAGAAATAAGAGCAACTAGGGAACAGCAGTAAAAATATTATAAATA
TAAATCAGGAGGAATTAATT

Downstream 100 bases:

>100_bases
ATCAGTATAATAAAAATGTCATACCAAAGCTGCCACTTTATAGTAAATGAGTGGCAGCTTTTATAATGTGGATATTTATG
AAAATTTCGTAAACAGATAA

Product: Glycoside Hydrolase Family 2 candidate b-glucuronidase

Products: NA

Alternate protein names: GUS; Beta-D-glucuronoside glucuronosohydrolase [H]

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MLYPVLTQSRLLSDLSGVWDFKLDNGKGFEEKWYEKPLKDADTMPVPASYNDLKEGTDFRDHYGWVFYQRNISVPEYVKS
QRIVLRCAAVTHYAMIYLNGKLICEHKGGFLPFEVELNDDLQDGDNLLTIAVNNVIDYTTLPVGGKANMMSGMMGGMGAG
ASDKPQNNPNFDFFNYCGITRPVKIYTTPETYINDITVTADIDFTKEEPSAVLNYNVEIKGKDYNNITCKVELFDEEGTK
LSETEGSEGTFEISNVRLWQPLNAYLYKIKVTAGQDVYTLPYGVRSVRVDGTKFLINEKPFYFKGYGKHEDTFPNGRGIN
LPMNTKDISIMKWQHANSFRTSHYPYSEEMMRLCDEEGIVVIDETTAVGVNLQFGGGANFGGERIGTFDKEHGVQTQEHH
KDVIRDLISRDKNHACVVMWSIANEPDSAAEGAYDYFKPLYDLARELDPQKRPCTLVSVQGTTADTDCSSQLSDVICLNR
YYGWYFGGPDLEVSEIGLRKELSDWGKLGKPVMFTEYGADTVSGLHDTTSVMYTEEYQVEYYEMNNKVFDEFDFVVGEQA
WNFADFATSQSLLRVQGNKKGLFTRDRKPKMVAHYFRNRWSTIPEFGYKTK

Sequences:

>Translated_611_residues
MLYPVLTQSRLLSDLSGVWDFKLDNGKGFEEKWYEKPLKDADTMPVPASYNDLKEGTDFRDHYGWVFYQRNISVPEYVKS
QRIVLRCAAVTHYAMIYLNGKLICEHKGGFLPFEVELNDDLQDGDNLLTIAVNNVIDYTTLPVGGKANMMSGMMGGMGAG
ASDKPQNNPNFDFFNYCGITRPVKIYTTPETYINDITVTADIDFTKEEPSAVLNYNVEIKGKDYNNITCKVELFDEEGTK
LSETEGSEGTFEISNVRLWQPLNAYLYKIKVTAGQDVYTLPYGVRSVRVDGTKFLINEKPFYFKGYGKHEDTFPNGRGIN
LPMNTKDISIMKWQHANSFRTSHYPYSEEMMRLCDEEGIVVIDETTAVGVNLQFGGGANFGGERIGTFDKEHGVQTQEHH
KDVIRDLISRDKNHACVVMWSIANEPDSAAEGAYDYFKPLYDLARELDPQKRPCTLVSVQGTTADTDCSSQLSDVICLNR
YYGWYFGGPDLEVSEIGLRKELSDWGKLGKPVMFTEYGADTVSGLHDTTSVMYTEEYQVEYYEMNNKVFDEFDFVVGEQA
WNFADFATSQSLLRVQGNKKGLFTRDRKPKMVAHYFRNRWSTIPEFGYKTK
>Mature_611_residues
MLYPVLTQSRLLSDLSGVWDFKLDNGKGFEEKWYEKPLKDADTMPVPASYNDLKEGTDFRDHYGWVFYQRNISVPEYVKS
QRIVLRCAAVTHYAMIYLNGKLICEHKGGFLPFEVELNDDLQDGDNLLTIAVNNVIDYTTLPVGGKANMMSGMMGGMGAG
ASDKPQNNPNFDFFNYCGITRPVKIYTTPETYINDITVTADIDFTKEEPSAVLNYNVEIKGKDYNNITCKVELFDEEGTK
LSETEGSEGTFEISNVRLWQPLNAYLYKIKVTAGQDVYTLPYGVRSVRVDGTKFLINEKPFYFKGYGKHEDTFPNGRGIN
LPMNTKDISIMKWQHANSFRTSHYPYSEEMMRLCDEEGIVVIDETTAVGVNLQFGGGANFGGERIGTFDKEHGVQTQEHH
KDVIRDLISRDKNHACVVMWSIANEPDSAAEGAYDYFKPLYDLARELDPQKRPCTLVSVQGTTADTDCSSQLSDVICLNR
YYGWYFGGPDLEVSEIGLRKELSDWGKLGKPVMFTEYGADTVSGLHDTTSVMYTEEYQVEYYEMNNKVFDEFDFVVGEQA
WNFADFATSQSLLRVQGNKKGLFTRDRKPKMVAHYFRNRWSTIPEFGYKTK

Specific function: Unknown

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=638, Percent_Identity=40.4388714733542, Blast_Score=449, Evalue=1e-126,
Organism=Escherichia coli, GI1787903, Length=619, Percent_Identity=44.7495961227787, Blast_Score=516, Evalue=1e-147,
Organism=Escherichia coli, GI48994920, Length=473, Percent_Identity=23.8900634249471, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1786539, Length=553, Percent_Identity=24.5931283905967, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17510825, Length=627, Percent_Identity=35.5661881977671, Blast_Score=371, Evalue=1e-103,
Organism=Drosophila melanogaster, GI62471735, Length=631, Percent_Identity=37.4009508716323, Blast_Score=395, Evalue=1e-110,
Organism=Drosophila melanogaster, GI19922582, Length=631, Percent_Identity=37.4009508716323, Blast_Score=395, Evalue=1e-110,
Organism=Drosophila melanogaster, GI24655438, Length=631, Percent_Identity=37.4009508716323, Blast_Score=394, Evalue=1e-110,
Organism=Drosophila melanogaster, GI24651745, Length=637, Percent_Identity=35.3218210361067, Blast_Score=372, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.31 [H]

Molecular weight: Translated: 69531; Mature: 69531

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00719 GLYCOSYL_HYDROL_F2_1 ; PS00608 GLYCOSYL_HYDROL_F2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYPVLTQSRLLSDLSGVWDFKLDNGKGFEEKWYEKPLKDADTMPVPASYNDLKEGTDFR
CCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCC
DHYGWVFYQRNISVPEYVKSQRIVLRCAAVTHYAMIYLNGKLICEHKGGFLPFEVELNDD
CCCCEEEEEECCCCHHHHCCCEEEEEEHHHHEEEEEEECCEEEEEECCCEEEEEEEECCC
LQDGDNLLTIAVNNVIDYTTLPVGGKANMMSGMMGGMGAGASDKPQNNPNFDFFNYCGIT
CCCCCCEEEEEECCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCC
RPVKIYTTPETYINDITVTADIDFTKEEPSAVLNYNVEIKGKDYNNITCKVELFDEEGTK
CCEEEEECCHHHHCCEEEEEEEECCCCCCCEEEEEEEEEECCCCCCEEEEEEEECCCCCE
LSETEGSEGTFEISNVRLWQPLNAYLYKIKVTAGQDVYTLPYGVRSVRVDGTKFLINEKP
ECCCCCCCCEEEECCEEEECCCCEEEEEEEEECCCEEEECCCCCEEEEECCEEEEECCCC
FYFKGYGKHEDTFPNGRGINLPMNTKDISIMKWQHANSFRTSHYPYSEEMMRLCDEEGIV
EEEECCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCEE
VIDETTAVGVNLQFGGGANFGGERIGTFDKEHGVQTQEHHKDVIRDLISRDKNHACVVMW
EEECCEEEEEEEEECCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCCCCEEEEEE
SIANEPDSAAEGAYDYFKPLYDLARELDPQKRPCTLVSVQGTTADTDCSSQLSDVICLNR
EECCCCCCHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHC
YYGWYFGGPDLEVSEIGLRKELSDWGKLGKPVMFTEYGADTVSGLHDTTSVMYTEEYQVE
CCCEEECCCCCCHHHHCHHHHHHHHHHCCCCEEEEECCCHHHCCCCCCCEEEEEECEEEE
YYEMNNKVFDEFDFVVGEQAWNFADFATSQSLLRVQGNKKGLFTRDRKPKMVAHYFRNRW
EEECCCCHHHHHHHEECCCCCCHHHHHCCCCEEEEECCCCCCEECCCCCHHHHHHHHHHC
STIPEFGYKTK
CCCCCCCCCCC
>Mature Secondary Structure
MLYPVLTQSRLLSDLSGVWDFKLDNGKGFEEKWYEKPLKDADTMPVPASYNDLKEGTDFR
CCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCC
DHYGWVFYQRNISVPEYVKSQRIVLRCAAVTHYAMIYLNGKLICEHKGGFLPFEVELNDD
CCCCEEEEEECCCCHHHHCCCEEEEEEHHHHEEEEEEECCEEEEEECCCEEEEEEEECCC
LQDGDNLLTIAVNNVIDYTTLPVGGKANMMSGMMGGMGAGASDKPQNNPNFDFFNYCGIT
CCCCCCEEEEEECCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCC
RPVKIYTTPETYINDITVTADIDFTKEEPSAVLNYNVEIKGKDYNNITCKVELFDEEGTK
CCEEEEECCHHHHCCEEEEEEEECCCCCCCEEEEEEEEEECCCCCCEEEEEEEECCCCCE
LSETEGSEGTFEISNVRLWQPLNAYLYKIKVTAGQDVYTLPYGVRSVRVDGTKFLINEKP
ECCCCCCCCEEEECCEEEECCCCEEEEEEEEECCCEEEECCCCCEEEEECCEEEEECCCC
FYFKGYGKHEDTFPNGRGINLPMNTKDISIMKWQHANSFRTSHYPYSEEMMRLCDEEGIV
EEEECCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCEE
VIDETTAVGVNLQFGGGANFGGERIGTFDKEHGVQTQEHHKDVIRDLISRDKNHACVVMW
EEECCEEEEEEEEECCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCCCCEEEEEE
SIANEPDSAAEGAYDYFKPLYDLARELDPQKRPCTLVSVQGTTADTDCSSQLSDVICLNR
EECCCCCCHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHC
YYGWYFGGPDLEVSEIGLRKELSDWGKLGKPVMFTEYGADTVSGLHDTTSVMYTEEYQVE
CCCEEECCCCCCHHHHCHHHHHHHHHHCCCCEEEEECCCHHHCCCCCCCEEEEEECEEEE
YYEMNNKVFDEFDFVVGEQAWNFADFATSQSLLRVQGNKKGLFTRDRKPKMVAHYFRNRW
EEECCCCHHHHHHHEECCCCCCHHHHHCCCCEEEEECCCCCCEECCCCCHHHHHHHHHHC
STIPEFGYKTK
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534890; 8125312; 2103475; 9097039; 9278503 [H]