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The map label for this gene is yeeO [C]

Identifier: 238922353

GI number: 238922353

Start: 560043

End: 561464

Strand: Reverse

Name: yeeO [C]

Synonym: EUBELI_20589

Alternate gene names: 238922353

Gene position: 561464-560043 (Counterclockwise)

Preceding gene: 238922354

Following gene: 238922352

Centisome position: 89.58

GC content: 38.12

Gene sequence:

>1422_bases
ATGGTCAGTATATGTGTGAAAGACATCTGGCAATTAAACAGAACGAAGAGGTTTATGATGAAGAATAATAATATGACAAG
AAATCTTGGAGAGGGAAATATATCAAAGCTTCTTGCTTCGCTTGCAATTCCTGCAGTTGTGGCACAGGTTGTTAATCTGC
TGTATAACATAGTTGACCGTGTATATATAGGACATATTCCGGGTATTGGGGCTAATGCTCTTACAGGGGTCGGACTTTTT
ACTCCTATACTTATGCTTATTAATGCATTCGCAATGCTCGCCGGTTCAGGAGGAGCACCAAGGGCAGCAATATTTATGGG
AAAGAAGGACAATGATACAGCTGAGAGAATTATAGGAAACTGTTTTACATTTATAATGATATGTGCGGTTGTATTGACGG
CGGTGTTTTATGTATCAGCACCACAGCTTTTAAGATGGTTTGGCGCAAGTGATGCAACGCTTCCATATGCTTTGTCATAT
GCAAGAATATATATTCTTGGAAGCATATTTGTCCTGATTGTTATGGCAATGAATATGTTTATCACAACACAGGGGTTTGC
TAAGATCAGCATGCTGACTACAGTAATTGGTGCAGTGATTAATATTGTTCTGGATCCTATATTTATATTTGTATTTAATA
TGGGAGTAAGAGGAGCAGCACTGGCAACAGTGCTTAGTCAGGCTGTCGGAGCTGTGTGGATTCTGCATTTTCTGACGGGT
AACAAGACAATACTGCGTCTTAAGAAAGCTAACCTAAGACTTGATGCGAAGATAATCGGACCGTGTCTTGCACTCGGAAT
ATCAACATTTGTAATGTTATCTACAGAGAGTATTTTGTCAATCAGCTTTACCTCAAGTCTTTCCAGATACGGCGGAGACC
TTGCGGTAGGAGCAATGACAATTATAACAAGCACTAATCAGCTTATTGTTATGCCGTTACAGGGAATATGTCAGGGTGGA
CAGCCGGTTATCAGTTACAACTATGGAGCAAAGAATAATGACAGGGTTAAGAAAGCATTTTTTACGCAGTTTAAAGCATG
TGTAATATTCACATGTATAAGCTGGGCAATTATGATGCTTACACCACAGCTGTTTGCCGGTATATTTACAAGTGACAAAG
TACTTGTGAATTATACAGCATGGGCATTGAGAATATATATGGCAGGAATATTTGCAATGGGATTCCAGGTAAGCTGTCAG
CAGAGTTTTATGGCGTTGGGACAGGCAAAAGTCAGTCTTATACTGGCATGTTTAAGGAAACTTATATTGTTGATACCGCT
TATATTCATATTACCATTGATTTTTCAAGATAAAGTATTTGCTGTATTTCTTGCAGAGCCGGTAAGTGATATTATTGCGG
CTATTGTAACAACGATAGTATTTATGTTTAAGTTTAATAATATATTATCTGAAAATGAATAA

Upstream 100 bases:

>100_bases
GTGGCAGCTTTTATAATGTGGATATTTATGAAAATTTCGTAAACAGATAAAAATCTATATACTATGTAAATAATTAATGA
TATTATAGTTAAATAAATTA

Downstream 100 bases:

>100_bases
TATAAAAAATTTTAATGAGTAGCAGGAAAGGGGTAATGGGAATGAACAATATGGATAATTACATGGAGCAGATGGCGGTT
CTTTGTGAAAACAATGACAG

Product: multidrug resistance protein, MATE family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MVSICVKDIWQLNRTKRFMMKNNNMTRNLGEGNISKLLASLAIPAVVAQVVNLLYNIVDRVYIGHIPGIGANALTGVGLF
TPILMLINAFAMLAGSGGAPRAAIFMGKKDNDTAERIIGNCFTFIMICAVVLTAVFYVSAPQLLRWFGASDATLPYALSY
ARIYILGSIFVLIVMAMNMFITTQGFAKISMLTTVIGAVINIVLDPIFIFVFNMGVRGAALATVLSQAVGAVWILHFLTG
NKTILRLKKANLRLDAKIIGPCLALGISTFVMLSTESILSISFTSSLSRYGGDLAVGAMTIITSTNQLIVMPLQGICQGG
QPVISYNYGAKNNDRVKKAFFTQFKACVIFTCISWAIMMLTPQLFAGIFTSDKVLVNYTAWALRIYMAGIFAMGFQVSCQ
QSFMALGQAKVSLILACLRKLILLIPLIFILPLIFQDKVFAVFLAEPVSDIIAAIVTTIVFMFKFNNILSENE

Sequences:

>Translated_473_residues
MVSICVKDIWQLNRTKRFMMKNNNMTRNLGEGNISKLLASLAIPAVVAQVVNLLYNIVDRVYIGHIPGIGANALTGVGLF
TPILMLINAFAMLAGSGGAPRAAIFMGKKDNDTAERIIGNCFTFIMICAVVLTAVFYVSAPQLLRWFGASDATLPYALSY
ARIYILGSIFVLIVMAMNMFITTQGFAKISMLTTVIGAVINIVLDPIFIFVFNMGVRGAALATVLSQAVGAVWILHFLTG
NKTILRLKKANLRLDAKIIGPCLALGISTFVMLSTESILSISFTSSLSRYGGDLAVGAMTIITSTNQLIVMPLQGICQGG
QPVISYNYGAKNNDRVKKAFFTQFKACVIFTCISWAIMMLTPQLFAGIFTSDKVLVNYTAWALRIYMAGIFAMGFQVSCQ
QSFMALGQAKVSLILACLRKLILLIPLIFILPLIFQDKVFAVFLAEPVSDIIAAIVTTIVFMFKFNNILSENE
>Mature_473_residues
MVSICVKDIWQLNRTKRFMMKNNNMTRNLGEGNISKLLASLAIPAVVAQVVNLLYNIVDRVYIGHIPGIGANALTGVGLF
TPILMLINAFAMLAGSGGAPRAAIFMGKKDNDTAERIIGNCFTFIMICAVVLTAVFYVSAPQLLRWFGASDATLPYALSY
ARIYILGSIFVLIVMAMNMFITTQGFAKISMLTTVIGAVINIVLDPIFIFVFNMGVRGAALATVLSQAVGAVWILHFLTG
NKTILRLKKANLRLDAKIIGPCLALGISTFVMLSTESILSISFTSSLSRYGGDLAVGAMTIITSTNQLIVMPLQGICQGG
QPVISYNYGAKNNDRVKKAFFTQFKACVIFTCISWAIMMLTPQLFAGIFTSDKVLVNYTAWALRIYMAGIFAMGFQVSCQ
QSFMALGQAKVSLILACLRKLILLIPLIFILPLIFQDKVFAVFLAEPVSDIIAAIVTTIVFMFKFNNILSENE

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 51551; Mature: 51551

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSICVKDIWQLNRTKRFMMKNNNMTRNLGEGNISKLLASLAIPAVVAQVVNLLYNIVDR
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYIGHIPGIGANALTGVGLFTPILMLINAFAMLAGSGGAPRAAIFMGKKDNDTAERIIGN
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHH
CFTFIMICAVVLTAVFYVSAPQLLRWFGASDATLPYALSYARIYILGSIFVLIVMAMNMF
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITTQGFAKISMLTTVIGAVINIVLDPIFIFVFNMGVRGAALATVLSQAVGAVWILHFLTG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
NKTILRLKKANLRLDAKIIGPCLALGISTFVMLSTESILSISFTSSLSRYGGDLAVGAMT
CCEEEEEECCCCEECHHHHHHHHHHHHHHHHHEEHHHHHEEHHHHHHHHCCCCHHHHHHH
IITSTNQLIVMPLQGICQGGQPVISYNYGAKNNDRVKKAFFTQFKACVIFTCISWAIMML
EEECCCCEEEEECHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPQLFAGIFTSDKVLVNYTAWALRIYMAGIFAMGFQVSCQQSFMALGQAKVSLILACLRK
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LILLIPLIFILPLIFQDKVFAVFLAEPVSDIIAAIVTTIVFMFKFNNILSENE
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVSICVKDIWQLNRTKRFMMKNNNMTRNLGEGNISKLLASLAIPAVVAQVVNLLYNIVDR
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYIGHIPGIGANALTGVGLFTPILMLINAFAMLAGSGGAPRAAIFMGKKDNDTAERIIGN
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHH
CFTFIMICAVVLTAVFYVSAPQLLRWFGASDATLPYALSYARIYILGSIFVLIVMAMNMF
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITTQGFAKISMLTTVIGAVINIVLDPIFIFVFNMGVRGAALATVLSQAVGAVWILHFLTG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
NKTILRLKKANLRLDAKIIGPCLALGISTFVMLSTESILSISFTSSLSRYGGDLAVGAMT
CCEEEEEECCCCEECHHHHHHHHHHHHHHHHHEEHHHHHEEHHHHHHHHCCCCHHHHHHH
IITSTNQLIVMPLQGICQGGQPVISYNYGAKNNDRVKKAFFTQFKACVIFTCISWAIMML
EEECCCCEEEEECHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPQLFAGIFTSDKVLVNYTAWALRIYMAGIFAMGFQVSCQQSFMALGQAKVSLILACLRK
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LILLIPLIFILPLIFQDKVFAVFLAEPVSDIIAAIVTTIVFMFKFNNILSENE
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]