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The map label for this gene is yjmB [H]

Identifier: 238922355

GI number: 238922355

Start: 563485

End: 564885

Strand: Reverse

Name: yjmB [H]

Synonym: EUBELI_20591

Alternate gene names: 238922355

Gene position: 564885-563485 (Counterclockwise)

Preceding gene: 238922357

Following gene: 238922354

Centisome position: 90.13

GC content: 36.26

Gene sequence:

>1401_bases
ATGACAGATAACAATGGAAAGGTGAGGCCATTTGGTATAAAAGACAAGCTTGGTTATATGTTTGGTGATTTCGGTAACGA
TTTTACTTTTTTGTTATCAGCTATGTTTTTGTTGAAGTTTTATACTGATGTTATGGGGGTTTCAGCAGCACTGGTCGGTC
TTATGATGATGGCGGCAAGATTTGTTGATGCTATAACTGATGTAACAATGGGACAGATAGTTGACAGGAGCAGACCGGGA
AAGAAAGGCAAATTTGCACCATGGCTCAGACGAATGTGCGGTCCTGTTGCGTTAGCATCATTTCTGATGTATGCGACATG
GTTTAAAGATATGCCGATGGGATTTAAGATTTTCTGGATGTTTTTTACTTACCTTCTTTGGGGAAGTATATGCTACACAG
GAATTAATATTCCTTATGGTTCAATGGCATCAGCGATTTCAGACAATCCGACAGACAGAACTTCTCTTTCTAACTGGAGA
ACAATAGGAGCTACACTTGCTCAGACTGCGATAGGAGTTGTATTACCACTTGTAGTGTATTATACAGATGAAGCAGGAAA
TTCAGTATTATCCGGTCAGAAAATGATGCTTGGTGCTTTGGTATGTTCAATAGGAGCCGTAATCTGCTATATGCTTTGCT
ACAAAATGACAACGGAAAGAGTTAAGGTTGGACAGAACACACAGAAATTCTCGTTTGGAGAGCTTATAAAGGAACTTGCC
CATAATAGATCTTTAATAGGCATTATAGTATGTGCATTGGTATTTTTACTTGCACAGTTATCATTAAGTAACATGAACGC
ATATATTTATCCAAATTATTTTGGCAATATAAAAGCAATGTCGATTGCAAGTCTTTCAGGAACAATAGTAATACTTTTAC
TTTCAACATTTATTACAAAGCTTGCATCAAAAATTGGAAAGAAAGAATTGTCAGTTATAGGATGTATTATCAGTGCAGCT
TCATTTATAACATTATTTATAATTCACACACATAATGTATGGATTTGGATAGCTTTAATAATTATAGCAACAATCGGTAC
TTCAATGTTTAACATGGTTATATGGGCTATGATTACGGATGTTATCGATGAATCAGAAGTTCAGAATGGTGTACGTCAGG
ATGGTACAATTTACTCAGTATATTCATTTGCAAGAAAGTTAGGACAGGCATGTTCATCAGGTTTAGCGGGCGTACTTCTT
TCGATTGTTGGTTATACAACAGCTACAGCATTTGATCCTAAGGTTATTGACGGAATCTACAATGTGACATGTCTTATGCC
GGCAGCCGGAATGACATTATTATTGCTTGCATTAATATTCTTATATCCTTTGAATAAAAAGAGAGTAGAAGCAAATGCAG
CTAAGTTAAAAGAAATAAGAGCAACTAGGGAACAGCAGTAA

Upstream 100 bases:

>100_bases
GACATAGAAAAGAGAGCACATAATAGTGCACATAATATTTAAGGACGGTCTTTAAAGAAAAAATATCTATAATATTTAAT
AAAGTGATGGAGGTTTTATT

Downstream 100 bases:

>100_bases
AAATATTATAAATATAAATCAGGAGGAATTAATTATGTTATATCCAGTTTTAACACAGTCAAGATTATTAAGCGATTTAA
GCGGAGTTTGGGATTTTAAG

Product: glycoside/pentoside/hexuronide:cation symporter, GPH family

Products: Proton [Cytoplasm]; Glucuronides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MTDNNGKVRPFGIKDKLGYMFGDFGNDFTFLLSAMFLLKFYTDVMGVSAALVGLMMMAARFVDAITDVTMGQIVDRSRPG
KKGKFAPWLRRMCGPVALASFLMYATWFKDMPMGFKIFWMFFTYLLWGSICYTGINIPYGSMASAISDNPTDRTSLSNWR
TIGATLAQTAIGVVLPLVVYYTDEAGNSVLSGQKMMLGALVCSIGAVICYMLCYKMTTERVKVGQNTQKFSFGELIKELA
HNRSLIGIIVCALVFLLAQLSLSNMNAYIYPNYFGNIKAMSIASLSGTIVILLLSTFITKLASKIGKKELSVIGCIISAA
SFITLFIIHTHNVWIWIALIIIATIGTSMFNMVIWAMITDVIDESEVQNGVRQDGTIYSVYSFARKLGQACSSGLAGVLL
SIVGYTTATAFDPKVIDGIYNVTCLMPAAGMTLLLLALIFLYPLNKKRVEANAAKLKEIRATREQQ

Sequences:

>Translated_466_residues
MTDNNGKVRPFGIKDKLGYMFGDFGNDFTFLLSAMFLLKFYTDVMGVSAALVGLMMMAARFVDAITDVTMGQIVDRSRPG
KKGKFAPWLRRMCGPVALASFLMYATWFKDMPMGFKIFWMFFTYLLWGSICYTGINIPYGSMASAISDNPTDRTSLSNWR
TIGATLAQTAIGVVLPLVVYYTDEAGNSVLSGQKMMLGALVCSIGAVICYMLCYKMTTERVKVGQNTQKFSFGELIKELA
HNRSLIGIIVCALVFLLAQLSLSNMNAYIYPNYFGNIKAMSIASLSGTIVILLLSTFITKLASKIGKKELSVIGCIISAA
SFITLFIIHTHNVWIWIALIIIATIGTSMFNMVIWAMITDVIDESEVQNGVRQDGTIYSVYSFARKLGQACSSGLAGVLL
SIVGYTTATAFDPKVIDGIYNVTCLMPAAGMTLLLLALIFLYPLNKKRVEANAAKLKEIRATREQQ
>Mature_465_residues
TDNNGKVRPFGIKDKLGYMFGDFGNDFTFLLSAMFLLKFYTDVMGVSAALVGLMMMAARFVDAITDVTMGQIVDRSRPGK
KGKFAPWLRRMCGPVALASFLMYATWFKDMPMGFKIFWMFFTYLLWGSICYTGINIPYGSMASAISDNPTDRTSLSNWRT
IGATLAQTAIGVVLPLVVYYTDEAGNSVLSGQKMMLGALVCSIGAVICYMLCYKMTTERVKVGQNTQKFSFGELIKELAH
NRSLIGIIVCALVFLLAQLSLSNMNAYIYPNYFGNIKAMSIASLSGTIVILLLSTFITKLASKIGKKELSVIGCIISAAS
FITLFIIHTHNVWIWIALIIIATIGTSMFNMVIWAMITDVIDESEVQNGVRQDGTIYSVYSFARKLGQACSSGLAGVLLS
IVGYTTATAFDPKVIDGIYNVTCLMPAAGMTLLLLALIFLYPLNKKRVEANAAKLKEIRATREQQ

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Homo sapiens, GI42713696, Length=480, Percent_Identity=23.75, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI211063479, Length=439, Percent_Identity=23.6902050113895, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI122937339, Length=414, Percent_Identity=22.463768115942, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI1787902, Length=461, Percent_Identity=30.1518438177874, Blast_Score=187, Evalue=9e-49,
Organism=Escherichia coli, GI48994989, Length=477, Percent_Identity=28.7211740041929, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1786466, Length=469, Percent_Identity=29.4243070362473, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI145693206, Length=455, Percent_Identity=26.8131868131868, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1790561, Length=452, Percent_Identity=25, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI87082306, Length=466, Percent_Identity=25.5364806866953, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51243; Mature: 51112

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDNNGKVRPFGIKDKLGYMFGDFGNDFTFLLSAMFLLKFYTDVMGVSAALVGLMMMAAR
CCCCCCEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVDAITDVTMGQIVDRSRPGKKGKFAPWLRRMCGPVALASFLMYATWFKDMPMGFKIFWM
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FFTYLLWGSICYTGINIPYGSMASAISDNPTDRTSLSNWRTIGATLAQTAIGVVLPLVVY
HHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YTDEAGNSVLSGQKMMLGALVCSIGAVICYMLCYKMTTERVKVGQNTQKFSFGELIKELA
EECCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
HNRSLIGIIVCALVFLLAQLSLSNMNAYIYPNYFGNIKAMSIASLSGTIVILLLSTFITK
HCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEHEEEHHHHHHHHHHHHHHHHHH
LASKIGKKELSVIGCIISAASFITLFIIHTHNVWIWIALIIIATIGTSMFNMVIWAMITD
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIDESEVQNGVRQDGTIYSVYSFARKLGQACSSGLAGVLLSIVGYTTATAFDPKVIDGIY
HHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHH
NVTCLMPAAGMTLLLLALIFLYPLNKKRVEANAAKLKEIRATREQQ
HHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; Glucuronides [Periplasm] [C]

Specific reaction: Proton [Periplasm] + Glucuronides [Periplasm] = Proton [Cytoplasm] + Glucuronides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]