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The map label for this gene is glpR [H]

Identifier: 238921528

GI number: 238921528

Start: 3575044

End: 3575802

Strand: Reverse

Name: glpR [H]

Synonym: NT01EI_3680

Alternate gene names: 238921528

Gene position: 3575802-3575044 (Counterclockwise)

Preceding gene: 238921529

Following gene: 238921527

Centisome position: 93.8

GC content: 56.92

Gene sequence:

>759_bases
GTGAAACAAACGCAGCGCCATGAAGCGATTATCGATCTGGTCCGTCAGCGGGGCTATGTCAGCACCGAGGAGCTGGTCGA
ACACTTCGACGTGAGTCCGCAGACCATCCGCCGCGATCTGAATGACCTGGCTGAACAGAATAAGATCCACCGCCATCACG
GCGGCGCTGCGATGCCATCGAGTTCTGTCAACGCAGCCTATCACGATCGCAAGGGAATGTGGTCGGAAGAGAAGGCGCGT
ATTGCCCGGCAGGTCGCCAGCATGATCCCCGATGGCGCCACCCTGTTCATCGACATCGGTACTACGCCAGAGGCCGTTGC
CTATGCCCTGCTAAACCATCATAACCTGCGGGTGGTGACCAATAACCTCAACGTGGCCAGCTTGCTGATGGTGAAAGAGG
ATTTTCGCCTGATCTTGGCCGGTGGTGAAGTCCGCACCCGCGATGGCGGCATCGTCGGCGAGGCGACGCTCGACTTTATC
TCTCAGTTCCGCCTGGACTACGGTATCCTTGGCATCAGCGGTATCGATATGGACGGATCTCTGTTGGAGTTTGATTATCA
CGAGGTGCGCACCAAGCGGGCGATCATTGAGAATTCCCGCTGCGTGATGCTGGTAACGGATCACTCCAAATTTGGCCGTA
ACGCGATGGTGAATCTGGGGAGCATGGAGCTGGTGGACTATCTGTTTACCGATCAGCCGCCGCCGCAGGGACTGCAAAAA
GTGATCGAACAGCACAGTGTTCAGCTGGAGATCTGCTAG

Upstream 100 bases:

>100_bases
GGCGTTCTGGGATATGCGCCATTTCCGCCGACAGTGAGGCTCCCGCCCGCTGTTCCGTTTTAATGCTGCCGGGAGAGCCG
GTAAACGCAGGGGAATTTAC

Downstream 100 bases:

>100_bases
GAGATCTCCCGTCACGACGTATGGCGTCGACGCTGATCCCATTCCCCCTCCGCCCGCAATGGGACGCTATCGGCGCCCCA
TTGACCGACCCCTGCGCCAC

Product: DNA-binding transcriptional repressor GlpR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKQTQRHEAIIDLVRQRGYVSTEELVEHFDVSPQTIRRDLNDLAEQNKIHRHHGGAAMPSSSVNAAYHDRKGMWSEEKAR
IARQVASMIPDGATLFIDIGTTPEAVAYALLNHHNLRVVTNNLNVASLLMVKEDFRLILAGGEVRTRDGGIVGEATLDFI
SQFRLDYGILGISGIDMDGSLLEFDYHEVRTKRAIIENSRCVMLVTDHSKFGRNAMVNLGSMELVDYLFTDQPPPQGLQK
VIEQHSVQLEIC

Sequences:

>Translated_252_residues
MKQTQRHEAIIDLVRQRGYVSTEELVEHFDVSPQTIRRDLNDLAEQNKIHRHHGGAAMPSSSVNAAYHDRKGMWSEEKAR
IARQVASMIPDGATLFIDIGTTPEAVAYALLNHHNLRVVTNNLNVASLLMVKEDFRLILAGGEVRTRDGGIVGEATLDFI
SQFRLDYGILGISGIDMDGSLLEFDYHEVRTKRAIIENSRCVMLVTDHSKFGRNAMVNLGSMELVDYLFTDQPPPQGLQK
VIEQHSVQLEIC
>Mature_252_residues
MKQTQRHEAIIDLVRQRGYVSTEELVEHFDVSPQTIRRDLNDLAEQNKIHRHHGGAAMPSSSVNAAYHDRKGMWSEEKAR
IARQVASMIPDGATLFIDIGTTPEAVAYALLNHHNLRVVTNNLNVASLLMVKEDFRLILAGGEVRTRDGGIVGEATLDFI
SQFRLDYGILGISGIDMDGSLLEFDYHEVRTKRAIIENSRCVMLVTDHSKFGRNAMVNLGSMELVDYLFTDQPPPQGLQK
VIEQHSVQLEIC

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=252, Percent_Identity=78.1746031746032, Blast_Score=418, Evalue=1e-118,
Organism=Escherichia coli, GI87082344, Length=244, Percent_Identity=42.2131147540984, Blast_Score=216, Evalue=8e-58,
Organism=Escherichia coli, GI1789059, Length=253, Percent_Identity=29.2490118577075, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1789519, Length=244, Percent_Identity=28.6885245901639, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI226510968, Length=250, Percent_Identity=29.2, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788069, Length=251, Percent_Identity=26.6932270916335, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789170, Length=233, Percent_Identity=29.1845493562232, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1787063, Length=224, Percent_Identity=27.6785714285714, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790753, Length=251, Percent_Identity=23.1075697211155, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787540, Length=228, Percent_Identity=27.6315789473684, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790635, Length=257, Percent_Identity=24.124513618677, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28279; Mature: 28279

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTQRHEAIIDLVRQRGYVSTEELVEHFDVSPQTIRRDLNDLAEQNKIHRHHGGAAMPS
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SSVNAAYHDRKGMWSEEKARIARQVASMIPDGATLFIDIGTTPEAVAYALLNHHNLRVVT
CCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEE
NNLNVASLLMVKEDFRLILAGGEVRTRDGGIVGEATLDFISQFRLDYGILGISGIDMDGS
CCCCEEHHEEECCCCEEEEECCEEEECCCCEEHHHHHHHHHHHHHHHCEEEEECCCCCCC
LLEFDYHEVRTKRAIIENSRCVMLVTDHSKFGRNAMVNLGSMELVDYLFTDQPPPQGLQK
EEECHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEECCHHHHHHHHHCCCCCHHHHHH
VIEQHSVQLEIC
HHHHCCCEEEEC
>Mature Secondary Structure
MKQTQRHEAIIDLVRQRGYVSTEELVEHFDVSPQTIRRDLNDLAEQNKIHRHHGGAAMPS
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SSVNAAYHDRKGMWSEEKARIARQVASMIPDGATLFIDIGTTPEAVAYALLNHHNLRVVT
CCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEE
NNLNVASLLMVKEDFRLILAGGEVRTRDGGIVGEATLDFISQFRLDYGILGISGIDMDGS
CCCCEEHHEEECCCCEEEEECCEEEECCCCEEHHHHHHHHHHHHHHHCEEEEECCCCCCC
LLEFDYHEVRTKRAIIENSRCVMLVTDHSKFGRNAMVNLGSMELVDYLFTDQPPPQGLQK
EEECHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEECCHHHHHHHHHCCCCCHHHHHH
VIEQHSVQLEIC
HHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]