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The map label for this gene is glpG [H]

Identifier: 238921529

GI number: 238921529

Start: 3575866

End: 3576687

Strand: Reverse

Name: glpG [H]

Synonym: NT01EI_3681

Alternate gene names: 238921529

Gene position: 3576687-3575866 (Counterclockwise)

Preceding gene: 238921530

Following gene: 238921528

Centisome position: 93.82

GC content: 62.65

Gene sequence:

>822_bases
GTGATCACATTGCCCAACCCGCGTTTGGCACAGGCATTTATTGACTATATGGCGACACAGGGTGTGCGTCTGGAGGCGGA
GAGCGGGTCGCAGGGCGTAGCCCTGTGGCTGGCGGATGATAGCCGTTTGGCGCAGGTCGAGCAGGAGCTGCAGCGTTTTT
TGCAGGCGCCACAGCACCCGCGCTATCAGGCCGCCAGCTGGCAAAGCGGCTCGACCCACAGCGGGCTGCGCTATGCCCGT
TTCGGCTACCTGCGCAGCTTTGCCCGCCAGAGCGGCCCGTTGACGATCGGGGTGACGCTGCTGTGCATCCTGGTGTATCT
GCTGCAGCTGGCGCTGGGCGATGGCGCGGTGATGGCCTATCTGGCCTGGCCCGCGGATGCGGCGCAGCACTATCAGCTGT
GGCGCTACTTCACACCGGCGTTGCTGCACTTTTCACCGCTGCACATCATTTTCAACCTGATGTGGTGGTGGTATTTGGGC
GGTCAGGTTGAGAAGCGTCTAGGGGCCGCCAAGCTGGCGCAGATAGCGCTGGTTTCCGCGCTGATGAGCGCCTGGGCACA
GTCGCTGTTCAGCGGGATTTTCTTCGGCGGTCTGTCCGGTGTCGTGTATGCCCTGATGGGCTATGTCTGGTGGTGCGGCG
AACGTGCACCGCAGTTTGGCGTCGCCATGCCGCGCGGCCTGATGCTGTTTTCGCTGCTGTGGCTGGTGGCCGGCTATTTC
AACTGGTTTGGCCTGGCGATTGCCAATGCCGCTCATGCCGGTGGCCTGGTAATAGGCCTGCTGATGGCGTTCTGGGATAT
GCGCCATTTCCGCCGACAGTGA

Upstream 100 bases:

>100_bases
GACGCCTGGCAACGGGCTTACCCTGAAGAGGTGGCCCGCGGCGGCGACTGAGGCACGTACCGTCAGCGGTTATCGATATA
AGCAGGTATTCATGGTTCGT

Downstream 100 bases:

>100_bases
GGCTCCCGCCCGCTGTTCCGTTTTAATGCTGCCGGGAGAGCCGGTAAACGCAGGGGAATTTACGTGAAACAAACGCAGCG
CCATGAAGCGATTATCGATC

Product: intramembrane serine protease GlpG

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MITLPNPRLAQAFIDYMATQGVRLEAESGSQGVALWLADDSRLAQVEQELQRFLQAPQHPRYQAASWQSGSTHSGLRYAR
FGYLRSFARQSGPLTIGVTLLCILVYLLQLALGDGAVMAYLAWPADAAQHYQLWRYFTPALLHFSPLHIIFNLMWWWYLG
GQVEKRLGAAKLAQIALVSALMSAWAQSLFSGIFFGGLSGVVYALMGYVWWCGERAPQFGVAMPRGLMLFSLLWLVAGYF
NWFGLAIANAAHAGGLVIGLLMAFWDMRHFRRQ

Sequences:

>Translated_273_residues
MITLPNPRLAQAFIDYMATQGVRLEAESGSQGVALWLADDSRLAQVEQELQRFLQAPQHPRYQAASWQSGSTHSGLRYAR
FGYLRSFARQSGPLTIGVTLLCILVYLLQLALGDGAVMAYLAWPADAAQHYQLWRYFTPALLHFSPLHIIFNLMWWWYLG
GQVEKRLGAAKLAQIALVSALMSAWAQSLFSGIFFGGLSGVVYALMGYVWWCGERAPQFGVAMPRGLMLFSLLWLVAGYF
NWFGLAIANAAHAGGLVIGLLMAFWDMRHFRRQ
>Mature_273_residues
MITLPNPRLAQAFIDYMATQGVRLEAESGSQGVALWLADDSRLAQVEQELQRFLQAPQHPRYQAASWQSGSTHSGLRYAR
FGYLRSFARQSGPLTIGVTLLCILVYLLQLALGDGAVMAYLAWPADAAQHYQLWRYFTPALLHFSPLHIIFNLMWWWYLG
GQVEKRLGAAKLAQIALVSALMSAWAQSLFSGIFFGGLSGVVYALMGYVWWCGERAPQFGVAMPRGLMLFSLLWLVAGYF
NWFGLAIANAAHAGGLVIGLLMAFWDMRHFRRQ

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=274, Percent_Identity=54.3795620437956, Blast_Score=298, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 30585; Mature: 30585

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLPNPRLAQAFIDYMATQGVRLEAESGSQGVALWLADDSRLAQVEQELQRFLQAPQHP
CCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC
RYQAASWQSGSTHSGLRYARFGYLRSFARQSGPLTIGVTLLCILVYLLQLALGDGAVMAY
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEE
LAWPADAAQHYQLWRYFTPALLHFSPLHIIFNLMWWWYLGGQVEKRLGAAKLAQIALVSA
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LMSAWAQSLFSGIFFGGLSGVVYALMGYVWWCGERAPQFGVAMPRGLMLFSLLWLVAGYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NWFGLAIANAAHAGGLVIGLLMAFWDMRHFRRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITLPNPRLAQAFIDYMATQGVRLEAESGSQGVALWLADDSRLAQVEQELQRFLQAPQHP
CCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCC
RYQAASWQSGSTHSGLRYARFGYLRSFARQSGPLTIGVTLLCILVYLLQLALGDGAVMAY
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCEEEE
LAWPADAAQHYQLWRYFTPALLHFSPLHIIFNLMWWWYLGGQVEKRLGAAKLAQIALVSA
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LMSAWAQSLFSGIFFGGLSGVVYALMGYVWWCGERAPQFGVAMPRGLMLFSLLWLVAGYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NWFGLAIANAAHAGGLVIGLLMAFWDMRHFRRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA