Click here to switch to the map view.

The map label for this gene is glpD [H]

Identifier: 238921527

GI number: 238921527

Start: 3573216

End: 3574724

Strand: Reverse

Name: glpD [H]

Synonym: NT01EI_3679

Alternate gene names: 238921527

Gene position: 3574724-3573216 (Counterclockwise)

Preceding gene: 238921528

Following gene: 238921517

Centisome position: 93.77

GC content: 64.02

Gene sequence:

>1509_bases
GTGGACATCAAAGACGTAATCGTCATCGGTGGCGGTATTAACGGTGCGGGTATCGCAGCCGATGCTGCCGGTCGCGGGCT
ATCGGTTCTGATGTTGGAGGCGCGCGACCTCGCCTGCGCCACTTCGTCGGCCAGCTCGAAGCTGATCCATGGGGGCCTGC
GCTATCTCGAACACTATGAGTTTCGATTGGTGAGCGAGGCTTTGGCGGAGCGTGAGGTGCTGCTGAAGATGGCGCCGCAC
ATCGCCTTTCCGCTGCGCTTTCGCCTGCCGCATCAGCCGTATTTACGCCCGGCCTGGATGATCCGCGCGGGCCTGTTTCT
GTATGATCATCTCGGTAAACGCACCAGCCTGCCGGGCAGCTGCGCCCTGCGCTTCGGCGCCAGCTCAGTGCTGAAGCCCA
GCCTGACGCGTGGCTTTGAGTACTCCGACTGCTGGGTGGACGATGCCCGCTTGGTGGTGCTCAACGCAATGGCGGTGGTG
GAGCGCGGCGGTGAGGTGCGCACGCGCACCGAGGTGACCCGCGCCTGGCGTGAGGAGGGCATATGGGTGGTGGAGGCGTG
CGACATCGACAGCGGGGAGACGCTGACCTGGCGCGCCCGTAGTCTGGTCAATGCCACCGGCCCGTGGGTCAAGCAGTTGT
TTGATGACGGACTGCAGCTCAAGTCCCCCTACGGTATCCGGCTGATCAAGGGGAGCCATATCGTGGTTCCGCGGGTGCAT
GACCAACCGCAGGCGTATATTTTGCAAAATGAGGATCAGCGCATCGTCTTCGTGATCCCGTGGCTGGATACGTTCTCCAT
CATCGGCACCACCGATGTGGAGTATCACGGCGATCCGCGCGCGGTGCAGATTGACGAGGGCGAAATAGACTATCTGCTTC
AGGTCTACAATCGCCACTTTGTGCGCCAGCTGAATCGGCAAGATATCGTCTGGACCTACGCTGGGGTGCGCCCGCTGTGC
GACGACGAGTCGGATTCGCCGCAGGCGATCACCCGTGACTATACGCTGGATATTCACGATAGGGACGGTGTGGCGCCGCT
GCTGTCGGTCTTCGGCGGTAAGCTGACCACCTATCGTAAGCTGGCGGAGCATGCGCTGGAGAAGCTGCGTCCCTACTATC
CGCACTGCGGCGATGCCTGGACCAGGGGGGCGGTGCTGCCCGGCGGGGAGATGGGTTGCGATCGGGACAGCTATGCCGTC
GCGCTGCGTCAGCGCCACGACTGGCTGCCTCAGGCGCTGGCGCGCCGCTATGCTCATACCTACGGCGCGCGCAGTGAGCG
GTTAATCGGCTCTGCGGCGTCACTGGCCGGTTTAGGCGAACACTTCGGCCATGGGCTGTATGCGGCGGAGCTCGACTATC
TGGCGGCGCACGAGTGGGTCGCGACGGCAGAGGATGCCCTGTGGCGCCGCACCAAGCTGGGGATGTGGCTGGATGACGCT
CAGCGTCAGCGGGTGGCCGAGTGGCTGGCGGCCCGGCGCCCGGCGGCGGAGACATCGTCGTCTTCCTGA

Upstream 100 bases:

>100_bases
GTGTTTTTATTTGGTCAACTGATGGTGTATTTGTTGCTTATCGCATATCATAATGCTCGAAATCGAACATTGTGGCGTGT
GGCAGAGAGCGGGAGGAGTC

Downstream 100 bases:

>100_bases
AAATAGCCAAGGCCCCCTGCGGGAGGCCTTGGCTCGCTGGGCCACTCAGAGCTTGACCGGTTTGATCTGCCAGATCTCGT
CGGCATACTCACGAATGGTG

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MDIKDVIVIGGGINGAGIAADAAGRGLSVLMLEARDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPH
IAFPLRFRLPHQPYLRPAWMIRAGLFLYDHLGKRTSLPGSCALRFGASSVLKPSLTRGFEYSDCWVDDARLVVLNAMAVV
ERGGEVRTRTEVTRAWREEGIWVVEACDIDSGETLTWRARSLVNATGPWVKQLFDDGLQLKSPYGIRLIKGSHIVVPRVH
DQPQAYILQNEDQRIVFVIPWLDTFSIIGTTDVEYHGDPRAVQIDEGEIDYLLQVYNRHFVRQLNRQDIVWTYAGVRPLC
DDESDSPQAITRDYTLDIHDRDGVAPLLSVFGGKLTTYRKLAEHALEKLRPYYPHCGDAWTRGAVLPGGEMGCDRDSYAV
ALRQRHDWLPQALARRYAHTYGARSERLIGSAASLAGLGEHFGHGLYAAELDYLAAHEWVATAEDALWRRTKLGMWLDDA
QRQRVAEWLAARRPAAETSSSS

Sequences:

>Translated_502_residues
MDIKDVIVIGGGINGAGIAADAAGRGLSVLMLEARDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPH
IAFPLRFRLPHQPYLRPAWMIRAGLFLYDHLGKRTSLPGSCALRFGASSVLKPSLTRGFEYSDCWVDDARLVVLNAMAVV
ERGGEVRTRTEVTRAWREEGIWVVEACDIDSGETLTWRARSLVNATGPWVKQLFDDGLQLKSPYGIRLIKGSHIVVPRVH
DQPQAYILQNEDQRIVFVIPWLDTFSIIGTTDVEYHGDPRAVQIDEGEIDYLLQVYNRHFVRQLNRQDIVWTYAGVRPLC
DDESDSPQAITRDYTLDIHDRDGVAPLLSVFGGKLTTYRKLAEHALEKLRPYYPHCGDAWTRGAVLPGGEMGCDRDSYAV
ALRQRHDWLPQALARRYAHTYGARSERLIGSAASLAGLGEHFGHGLYAAELDYLAAHEWVATAEDALWRRTKLGMWLDDA
QRQRVAEWLAARRPAAETSSSS
>Mature_502_residues
MDIKDVIVIGGGINGAGIAADAAGRGLSVLMLEARDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPH
IAFPLRFRLPHQPYLRPAWMIRAGLFLYDHLGKRTSLPGSCALRFGASSVLKPSLTRGFEYSDCWVDDARLVVLNAMAVV
ERGGEVRTRTEVTRAWREEGIWVVEACDIDSGETLTWRARSLVNATGPWVKQLFDDGLQLKSPYGIRLIKGSHIVVPRVH
DQPQAYILQNEDQRIVFVIPWLDTFSIIGTTDVEYHGDPRAVQIDEGEIDYLLQVYNRHFVRQLNRQDIVWTYAGVRPLC
DDESDSPQAITRDYTLDIHDRDGVAPLLSVFGGKLTTYRKLAEHALEKLRPYYPHCGDAWTRGAVLPGGEMGCDRDSYAV
ALRQRHDWLPQALARRYAHTYGARSERLIGSAASLAGLGEHFGHGLYAAELDYLAAHEWVATAEDALWRRTKLGMWLDDA
QRQRVAEWLAARRPAAETSSSS

Specific function: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses molecular oxygen or nitrate as electron acceptor [H]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=517, Percent_Identity=29.7872340425532, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI285002231, Length=517, Percent_Identity=29.7872340425532, Blast_Score=173, Evalue=3e-43,
Organism=Escherichia coli, GI2367226, Length=489, Percent_Identity=76.6871165644172, Blast_Score=741, Evalue=0.0,
Organism=Escherichia coli, GI1788574, Length=481, Percent_Identity=27.4428274428274, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534726, Length=515, Percent_Identity=29.5145631067961, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17509253, Length=521, Percent_Identity=28.4069097888676, Blast_Score=145, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6322036, Length=535, Percent_Identity=27.6635514018692, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI161077125, Length=516, Percent_Identity=30.6201550387597, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24653942, Length=516, Percent_Identity=30.6201550387597, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24653944, Length=516, Percent_Identity=30.6201550387597, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI20130025, Length=516, Percent_Identity=30.6201550387597, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24586295, Length=504, Percent_Identity=26.1904761904762, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI19921278, Length=509, Percent_Identity=26.7190569744597, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56230; Mature: 56230

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKDVIVIGGGINGAGIAADAAGRGLSVLMLEARDLACATSSASSKLIHGGLRYLEHYE
CCCCEEEEECCCCCCCCEECCCCCCCEEEEEEECCCHHEECCCCCHHHHHHHHHHHHHHH
FRLVSEALAEREVLLKMAPHIAFPLRFRLPHQPYLRPAWMIRAGLFLYDHLGKRTSLPGS
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCH
CALRFGASSVLKPSLTRGFEYSDCWVDDARLVVLNAMAVVERGGEVRTRTEVTRAWREEG
HEEECCCCHHCCCHHHCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHCC
IWVVEACDIDSGETLTWRARSLVNATGPWVKQLFDDGLQLKSPYGIRLIKGSHIVVPRVH
EEEEEEECCCCCCEEEEEHHHHHCCCCHHHHHHHHCCCEECCCCCEEEEECCEEEEECCC
DQPQAYILQNEDQRIVFVIPWLDTFSIIGTTDVEYHGDPRAVQIDEGEIDYLLQVYNRHF
CCCCEEEEECCCCEEEEEEECCCCEEEEECCCEEECCCCCEEEECCCCHHHHHHHHHHHH
VRQLNRQDIVWTYAGVRPLCDDESDSPQAITRDYTLDIHDRDGVAPLLSVFGGKLTTYRK
HHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHCCCHHHHHH
LAEHALEKLRPYYPHCGDAWTRGAVLPGGEMGCDRDSYAVALRQRHDWLPQALARRYAHT
HHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHH
YGARSERLIGSAASLAGLGEHFGHGLYAAELDYLAAHEWVATAEDALWRRTKLGMWLDDA
HCCCCHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
QRQRVAEWLAARRPAAETSSSS
HHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDIKDVIVIGGGINGAGIAADAAGRGLSVLMLEARDLACATSSASSKLIHGGLRYLEHYE
CCCCEEEEECCCCCCCCEECCCCCCCEEEEEEECCCHHEECCCCCHHHHHHHHHHHHHHH
FRLVSEALAEREVLLKMAPHIAFPLRFRLPHQPYLRPAWMIRAGLFLYDHLGKRTSLPGS
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCH
CALRFGASSVLKPSLTRGFEYSDCWVDDARLVVLNAMAVVERGGEVRTRTEVTRAWREEG
HEEECCCCHHCCCHHHCCCCCCCCCCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHCC
IWVVEACDIDSGETLTWRARSLVNATGPWVKQLFDDGLQLKSPYGIRLIKGSHIVVPRVH
EEEEEEECCCCCCEEEEEHHHHHCCCCHHHHHHHHCCCEECCCCCEEEEECCEEEEECCC
DQPQAYILQNEDQRIVFVIPWLDTFSIIGTTDVEYHGDPRAVQIDEGEIDYLLQVYNRHF
CCCCEEEEECCCCEEEEEEECCCCEEEEECCCEEECCCCCEEEECCCCHHHHHHHHHHHH
VRQLNRQDIVWTYAGVRPLCDDESDSPQAITRDYTLDIHDRDGVAPLLSVFGGKLTTYRK
HHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHCCCHHHHHH
LAEHALEKLRPYYPHCGDAWTRGAVLPGGEMGCDRDSYAVALRQRHDWLPQALARRYAHT
HHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHH
YGARSERLIGSAASLAGLGEHFGHGLYAAELDYLAAHEWVATAEDALWRRTKLGMWLDDA
HCCCCHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
QRQRVAEWLAARRPAAETSSSS
HHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1987111; 9278503; 3045087; 3045764 [H]