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The map label for this gene is codA [H]

Identifier: 238921463

GI number: 238921463

Start: 3501017

End: 3502300

Strand: Reverse

Name: codA [H]

Synonym: NT01EI_3615

Alternate gene names: 238921463

Gene position: 3502300-3501017 (Counterclockwise)

Preceding gene: 238921464

Following gene: 238921461

Centisome position: 91.87

GC content: 61.84

Gene sequence:

>1284_bases
ATGCAGAATAACGTACTGCGCGCCGTGATCAATGCCCGCCTGCCCGCGCGCGACGGGTGGTGGCAAATTACCTTGGAGCA
TGGCCTGATCGCGGCCATTACGCCGCAGCCCGCGCTACGGGCTGCGCAGCCGGATGAGCTGGATGCACAGCAGGGGCTGG
TGGTACCGCCCTTTGTCGAACCGCATATTCATCTGGATACGACGCAGACGGCGGGGCAGCCAGCCTGGAATCAGTCGGGA
ACCCTGTTTGAGGGGATCGAGCGCTGGGCCGAGCGCAAGGCGCAGCTGACCCACGATGACGTGAAACAGCGCGCCTGGCA
GACCTTGAAGTGGCAGATAGCGAACGGTATCCAGTACGTACGTAGCCACGTGGACGTCTCCGATCCGTCGCTGACGGCGT
TAAAGGCGATGCTGGAGGTACGCCAGGAGGTGGCGCCCTGGGTCGATCTGCAACTGGTCGCCTTTCCGCAGGAGGGGATA
CTCTCCTATCCAAACGGCGAGGATCTGCTGGAGGAGGCGCTGCGACTGGGCGCAGATGTGGTGGGGGCCATTCCTCATTT
TGAGTTTACCCGTGAATATGGTGTGGAGTCGCTTCATAAAGTCTTCGCACTGGCCGCGCGCTATGGCCGCCTGATCGATG
TTCATTGTGATGAAATAGACGATGAGCAGTCGCGCTTCGTTGAAACCGTGGCGGCACTGGCGCACCGCGAAGGCATGGGG
GCACGGGTGACCGCCAGCCATACCACGGCGATGCACTCTTACAACGGCGCCTATACATCGCGGCTGTTCCGGTTGCTGAA
GATGTCTCAGATTAACTTTGTCGCTAATCCGCTGGTCAACATCCATTTACAGGGGCGCTTCGATGACTATCCCAAGCGAC
GAGGCATCACCCGGGTGAAAGAGATGCTGCAGGCCGGGATCAACGTCTGCTTCGGCCATGATGATGTGTTTGACCCCTGG
TATCCGCTGGGTACCGCCAATATGCTGCAGGTGCTGCACATGGGGCTGCATGTCTGCCAACTGATGGGCTATGCCCAGAT
TGATGAGGGGCTGGCGCTGATCGGTTCGCATAGTGCCCGGACGCTCGGTCTGCAGGGATATGGGGTGGCGCCGGGCTGCC
GCGCCAGTCTGCTGGTGCTGCCGGCGGAGAGCGGGTTTGACGCGGTGCGCCGACAGGTGCCGGTGCGTTACTCCCTGCGT
GATGGCCGCCTGATCGCGGAGACCCGTCCGGCGCAGAGCCAGATTTATCTGCGGCAGGCGGAGCGCGTCGACTTCCGCCG
CTGA

Upstream 100 bases:

>100_bases
GGGATCGTTCCGCTGAACGCCGTATTGGGCGGCGCCCTGAGCTACGTGGTTCTCAGCCGCAGGGCGAGTCCTCAGAGAGA
AAATAGACTGGAGATCAGCC

Downstream 100 bases:

>100_bases
GTTCGGCGCGCGCAAAAAAACGGGACCTGCATGCAGGCCCCGTTGTTATGGGTATGGCGCAGTCTACTTGGCTGCGTGAC
CATGCAGGCGGTGCTTGGTG

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MQNNVLRAVINARLPARDGWWQITLEHGLIAAITPQPALRAAQPDELDAQQGLVVPPFVEPHIHLDTTQTAGQPAWNQSG
TLFEGIERWAERKAQLTHDDVKQRAWQTLKWQIANGIQYVRSHVDVSDPSLTALKAMLEVRQEVAPWVDLQLVAFPQEGI
LSYPNGEDLLEEALRLGADVVGAIPHFEFTREYGVESLHKVFALAARYGRLIDVHCDEIDDEQSRFVETVAALAHREGMG
ARVTASHTTAMHSYNGAYTSRLFRLLKMSQINFVANPLVNIHLQGRFDDYPKRRGITRVKEMLQAGINVCFGHDDVFDPW
YPLGTANMLQVLHMGLHVCQLMGYAQIDEGLALIGSHSARTLGLQGYGVAPGCRASLLVLPAESGFDAVRRQVPVRYSLR
DGRLIAETRPAQSQIYLRQAERVDFRR

Sequences:

>Translated_427_residues
MQNNVLRAVINARLPARDGWWQITLEHGLIAAITPQPALRAAQPDELDAQQGLVVPPFVEPHIHLDTTQTAGQPAWNQSG
TLFEGIERWAERKAQLTHDDVKQRAWQTLKWQIANGIQYVRSHVDVSDPSLTALKAMLEVRQEVAPWVDLQLVAFPQEGI
LSYPNGEDLLEEALRLGADVVGAIPHFEFTREYGVESLHKVFALAARYGRLIDVHCDEIDDEQSRFVETVAALAHREGMG
ARVTASHTTAMHSYNGAYTSRLFRLLKMSQINFVANPLVNIHLQGRFDDYPKRRGITRVKEMLQAGINVCFGHDDVFDPW
YPLGTANMLQVLHMGLHVCQLMGYAQIDEGLALIGSHSARTLGLQGYGVAPGCRASLLVLPAESGFDAVRRQVPVRYSLR
DGRLIAETRPAQSQIYLRQAERVDFRR
>Mature_427_residues
MQNNVLRAVINARLPARDGWWQITLEHGLIAAITPQPALRAAQPDELDAQQGLVVPPFVEPHIHLDTTQTAGQPAWNQSG
TLFEGIERWAERKAQLTHDDVKQRAWQTLKWQIANGIQYVRSHVDVSDPSLTALKAMLEVRQEVAPWVDLQLVAFPQEGI
LSYPNGEDLLEEALRLGADVVGAIPHFEFTREYGVESLHKVFALAARYGRLIDVHCDEIDDEQSRFVETVAALAHREGMG
ARVTASHTTAMHSYNGAYTSRLFRLLKMSQINFVANPLVNIHLQGRFDDYPKRRGITRVKEMLQAGINVCFGHDDVFDPW
YPLGTANMLQVLHMGLHVCQLMGYAQIDEGLALIGSHSARTLGLQGYGVAPGCRASLLVLPAESGFDAVRRQVPVRYSLR
DGRLIAETRPAQSQIYLRQAERVDFRR

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=427, Percent_Identity=81.4988290398126, Blast_Score=738, Evalue=0.0,
Organism=Escherichia coli, GI1786517, Length=414, Percent_Identity=24.3961352657005, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 47843; Mature: 47843

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNNVLRAVINARLPARDGWWQITLEHGLIAAITPQPALRAAQPDELDAQQGLVVPPFVE
CCCHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCCC
PHIHLDTTQTAGQPAWNQSGTLFEGIERWAERKAQLTHDDVKQRAWQTLKWQIANGIQYV
CCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RSHVDVSDPSLTALKAMLEVRQEVAPWVDLQLVAFPQEGILSYPNGEDLLEEALRLGADV
HHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCHH
VGAIPHFEFTREYGVESLHKVFALAARYGRLIDVHCDEIDDEQSRFVETVAALAHREGMG
HHCCCCHHHHHHHCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCC
ARVTASHTTAMHSYNGAYTSRLFRLLKMSQINFVANPLVNIHLQGRFDDYPKRRGITRVK
CEEEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHCCHHHHH
EMLQAGINVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQLMGYAQIDEGLALIGSHSAR
HHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCHHEEECCCCE
TLGLQGYGVAPGCRASLLVLPAESGFDAVRRQVPVRYSLRDGRLIAETRPAQSQIYLRQA
EECCCCCCCCCCCCCEEEEEECCCCHHHHHHCCCCEEECCCCEEEECCCCCHHHHHHHHH
ERVDFRR
HHCCCCC
>Mature Secondary Structure
MQNNVLRAVINARLPARDGWWQITLEHGLIAAITPQPALRAAQPDELDAQQGLVVPPFVE
CCCHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCCC
PHIHLDTTQTAGQPAWNQSGTLFEGIERWAERKAQLTHDDVKQRAWQTLKWQIANGIQYV
CCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
RSHVDVSDPSLTALKAMLEVRQEVAPWVDLQLVAFPQEGILSYPNGEDLLEEALRLGADV
HHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCHH
VGAIPHFEFTREYGVESLHKVFALAARYGRLIDVHCDEIDDEQSRFVETVAALAHREGMG
HHCCCCHHHHHHHCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCC
ARVTASHTTAMHSYNGAYTSRLFRLLKMSQINFVANPLVNIHLQGRFDDYPKRRGITRVK
CEEEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHCCHHHHH
EMLQAGINVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQLMGYAQIDEGLALIGSHSAR
HHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCHHEEECCCCE
TLGLQGYGVAPGCRASLLVLPAESGFDAVRRQVPVRYSLRDGRLIAETRPAQSQIYLRQA
EECCCCCCCCCCCCCEEEEEECCCCHHHHHHCCCCEEECCCCEEEECCCCCHHHHHHHHH
ERVDFRR
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]