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The map label for this gene is codB [H]

Identifier: 238921464

GI number: 238921464

Start: 3502290

End: 3503540

Strand: Reverse

Name: codB [H]

Synonym: NT01EI_3616

Alternate gene names: 238921464

Gene position: 3503540-3502290 (Counterclockwise)

Preceding gene: 238921466

Following gene: 238921463

Centisome position: 91.9

GC content: 60.99

Gene sequence:

>1251_bases
GTGTCGCAGGATAACAATTTCAGTCAGGGGCCCGTTCCGCCATCGGCGCGCAAGGGGGTGCTGGCATTAAGCTGTGTCAT
GCTGGGGTTAACCTTCTTTTCCGCCAGTATGTGGACCGGCGGCACGCTCGGCACTGGCCTTGGCTATCACGATTTTCTTC
TGGCCGTATTCATCGGTAATCTCCTCCTCGGCATCTATACCTCTACACTTGGCTATATCGGTGCAAAAACCGGTCTGACG
ACGCACCTGCTGGCGCGCTTCTCCTTTGGTGTTAAAGGCTCTTGGCTGCCTTCGCTGCTGCTGGGCGGCACGCAGGTGGG
ATGGTTTGGCGTCGGGGTCGCCATGTTCGCGATTCCGGTCAGTAAGGCGACCGGTCTGAATACCGATCTGCTGATCGCGC
TTTCCGGACTGCTGATGACCGTGACGGTGTTCTTTGGCATCTCGGCGTTGACGCTGCTGTCGGCGATCGCGGTACCGGCA
ATCGCGCTGCTCGGCGGCTACTCGGTGTGGCTGGCGATCGATGGCATGGGCGGGATGGATGCCCTGCGTGAGGTGGTTCC
CGCGCAGCCGCTGGATTTCAATTTGGCGCTGGCGCTGGTGGTCGGCTCCTTTATCAGCGCAGGCACGCTGACGGCGGACT
TTGTCCGCTTTGGCCGCAGCGCCAAGGTGGCGGTGCTGGTGACGATGGTGGCGTTCTTTCTCGGTAACTCGCTGATGTTT
ATCTTTGGCGCGACCGGCGCCGCGGTGCTGGGAATGTCTGACATCTCCGACGTCATGATAGCCCAAGGGCTGTTGCTGCC
CGCGATTGCGGTGCTGGGGCTGAATATCTGGACCACCAATGATAATGCGCTGTATGCCTCCGGTCTGGGATTCGCCAATA
TCACCGGGCTGTCGAGCAAGACGTTGTCGGTCGCCAACGGGATCATCGGGACCCTGTGCGCGCTGTGGCTGTATAACAAC
TTTGTCGGCTGGCTGACCTTCCTCTCCGCCGCCATTCCGCCGGTCGGTGGGGTGATCATCGCGGATTACCTGATGAACCG
GCGCCGTTACAGCAACTTTGCGGAGGCGGGCAGGGTCGCGGTAAATTGGAACGCCATTGCCGCCGTCGCCCTGGGCGTCG
CCGCGGGCCACGGGTTGCCGGGGATCGTTCCGCTGAACGCCGTATTGGGCGGCGCCCTGAGCTACGTGGTTCTCAGCCGC
AGGGCGAGTCCTCAGAGAGAAAATAGACTGGAGATCAGCCATGCAGAATAA

Upstream 100 bases:

>100_bases
AGAATAAATAACCAGCAAAGAAAACGTTTGCTTTTTGGCGTGAACTCTTTAGAATGCGCCAGATTTTTTTGTCTACCGCA
CAGAGATTAAGGAGGATTGC

Downstream 100 bases:

>100_bases
CGTACTGCGCGCCGTGATCAATGCCCGCCTGCCCGCGCGCGACGGGTGGTGGCAAATTACCTTGGAGCATGGCCTGATCG
CGGCCATTACGCCGCAGCCC

Product: cytosine permease

Products: Proton [Cytoplasm]; cytosine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MSQDNNFSQGPVPPSARKGVLALSCVMLGLTFFSASMWTGGTLGTGLGYHDFLLAVFIGNLLLGIYTSTLGYIGAKTGLT
THLLARFSFGVKGSWLPSLLLGGTQVGWFGVGVAMFAIPVSKATGLNTDLLIALSGLLMTVTVFFGISALTLLSAIAVPA
IALLGGYSVWLAIDGMGGMDALREVVPAQPLDFNLALALVVGSFISAGTLTADFVRFGRSAKVAVLVTMVAFFLGNSLMF
IFGATGAAVLGMSDISDVMIAQGLLLPAIAVLGLNIWTTNDNALYASGLGFANITGLSSKTLSVANGIIGTLCALWLYNN
FVGWLTFLSAAIPPVGGVIIADYLMNRRRYSNFAEAGRVAVNWNAIAAVALGVAAGHGLPGIVPLNAVLGGALSYVVLSR
RASPQRENRLEISHAE

Sequences:

>Translated_416_residues
MSQDNNFSQGPVPPSARKGVLALSCVMLGLTFFSASMWTGGTLGTGLGYHDFLLAVFIGNLLLGIYTSTLGYIGAKTGLT
THLLARFSFGVKGSWLPSLLLGGTQVGWFGVGVAMFAIPVSKATGLNTDLLIALSGLLMTVTVFFGISALTLLSAIAVPA
IALLGGYSVWLAIDGMGGMDALREVVPAQPLDFNLALALVVGSFISAGTLTADFVRFGRSAKVAVLVTMVAFFLGNSLMF
IFGATGAAVLGMSDISDVMIAQGLLLPAIAVLGLNIWTTNDNALYASGLGFANITGLSSKTLSVANGIIGTLCALWLYNN
FVGWLTFLSAAIPPVGGVIIADYLMNRRRYSNFAEAGRVAVNWNAIAAVALGVAAGHGLPGIVPLNAVLGGALSYVVLSR
RASPQRENRLEISHAE
>Mature_415_residues
SQDNNFSQGPVPPSARKGVLALSCVMLGLTFFSASMWTGGTLGTGLGYHDFLLAVFIGNLLLGIYTSTLGYIGAKTGLTT
HLLARFSFGVKGSWLPSLLLGGTQVGWFGVGVAMFAIPVSKATGLNTDLLIALSGLLMTVTVFFGISALTLLSAIAVPAI
ALLGGYSVWLAIDGMGGMDALREVVPAQPLDFNLALALVVGSFISAGTLTADFVRFGRSAKVAVLVTMVAFFLGNSLMFI
FGATGAAVLGMSDISDVMIAQGLLLPAIAVLGLNIWTTNDNALYASGLGFANITGLSSKTLSVANGIIGTLCALWLYNNF
VGWLTFLSAAIPPVGGVIIADYLMNRRRYSNFAEAGRVAVNWNAIAAVALGVAAGHGLPGIVPLNAVLGGALSYVVLSRR
ASPQRENRLEISHAE

Specific function: Required for cytosine transport into the cell [H]

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Escherichia coli, GI1786530, Length=416, Percent_Identity=85.3365384615385, Blast_Score=670, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248
- InterPro:   IPR012681 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 43101; Mature: 42970

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDNNFSQGPVPPSARKGVLALSCVMLGLTFFSASMWTGGTLGTGLGYHDFLLAVFIGN
CCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
LLLGIYTSTLGYIGAKTGLTTHLLARFSFGVKGSWLPSLLLGGTQVGWFGVGVAMFAIPV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
SKATGLNTDLLIALSGLLMTVTVFFGISALTLLSAIAVPAIALLGGYSVWLAIDGMGGMD
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHH
ALREVVPAQPLDFNLALALVVGSFISAGTLTADFVRFGRSAKVAVLVTMVAFFLGNSLMF
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEE
IFGATGAAVLGMSDISDVMIAQGLLLPAIAVLGLNIWTTNDNALYASGLGFANITGLSSK
EEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCCEECCCCCH
TLSVANGIIGTLCALWLYNNFVGWLTFLSAAIPPVGGVIIADYLMNRRRYSNFAEAGRVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHCCEE
VNWNAIAAVALGVAAGHGLPGIVPLNAVLGGALSYVVLSRRASPQRENRLEISHAE
EEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCC
>Mature Secondary Structure 
SQDNNFSQGPVPPSARKGVLALSCVMLGLTFFSASMWTGGTLGTGLGYHDFLLAVFIGN
CCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
LLLGIYTSTLGYIGAKTGLTTHLLARFSFGVKGSWLPSLLLGGTQVGWFGVGVAMFAIPV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
SKATGLNTDLLIALSGLLMTVTVFFGISALTLLSAIAVPAIALLGGYSVWLAIDGMGGMD
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHH
ALREVVPAQPLDFNLALALVVGSFISAGTLTADFVRFGRSAKVAVLVTMVAFFLGNSLMF
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEE
IFGATGAAVLGMSDISDVMIAQGLLLPAIAVLGLNIWTTNDNALYASGLGFANITGLSSK
EEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCCEECCCCCH
TLSVANGIIGTLCALWLYNNFVGWLTFLSAAIPPVGGVIIADYLMNRRRYSNFAEAGRVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHCCEE
VNWNAIAAVALGVAAGHGLPGIVPLNAVLGGALSYVVLSRRASPQRENRLEISHAE
EEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; cytosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + cytosine [Periplasm] = Proton [Cytoplasm] + cytosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]