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The map label for this gene is aroD [H]

Identifier: 238893049

GI number: 238893049

Start: 870562

End: 871329

Strand: Reverse

Name: aroD [H]

Synonym: KP1_0888

Alternate gene names: 238893049

Gene position: 871329-870562 (Counterclockwise)

Preceding gene: 238893050

Following gene: 238893047

Centisome position: 16.6

GC content: 57.55

Gene sequence:

>768_bases
ATGGATACCTACATGACAAATGCAGTAACCGTAAAGAACATCACCTTCCAGGAAGGGGAAACCCTCATTTGTGTACCGCT
GATCGGTAAAACCCTGGATGAGATACTGGGTAACGCCCACGGCCTGGTCGATGCCGGCGCCGATATTATCGAATGGCGCG
TTGACCACTTTGCCCAGGTCAGAGAGATGGCCCAGGTGATGGCCGCGCTGGCGGAAATCCGTGGCGCGCTGAAAGCGCTT
CCGCTGCTGTTTACCTTCCGCAGCAAGAAAGAAGGTGGCGAAACCGAGCTCAGCGACGAAGCCTATTTTGCGCTCAACCG
CGAGGCCGCACGCAGTGGACTGGTTGATGTTATCGATATCGAACTGTTCAATGATGAAGCGCAGATCCGCGCGCTGGTTG
ACGATGCGCATGCCGCGGGCGTCAAGGTGCTCATGAGTAATCATGATTTCCATAAGACCCCCGCTCAGGAAGATATTATC
TATCGCCTGCGCCGCATGCAGGATCTGGGGGCCGATCTGCCGAAGATCGCGGTGATGCCGCAGTCGCCGCAGGACGTACT
CACCTTGCTCGCCGCCACGCTGACCATGAAAGAGAAGTATGCGACGCGTCCGCTGATCACCATGTCGATGGGCAAATCCG
GTGGCGTTAGCCGGGTCACCGGGCGCTTGTTCGGTTCGGCGATGACCTTCGGTACCGTTGGTCAGGCCTCCGCGCCTGGG
CAGATCGCCATCGCTAAGCTGCGTGAAGTGATGGATATTCTCTCCTGA

Upstream 100 bases:

>100_bases
TGTGATCGCCCTGTACATCGGCTATCGTCAACTGCAGGCTCGGGCGGCGCAAAAAGTGTCACGCACCGCAGTCACCGCCT
GAAGTACAACGCGAAAAATA

Downstream 100 bases:

>100_bases
TATCCGGATGGCCCGGAGGTCACATCCGGGCCATCCGTTAACAGATCTTCTGGCTGTCGTGGATAACCACATTTTTAAAT
GACTCCAGCGCCGGAGAGAG

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MDTYMTNAVTVKNITFQEGETLICVPLIGKTLDEILGNAHGLVDAGADIIEWRVDHFAQVREMAQVMAALAEIRGALKAL
PLLFTFRSKKEGGETELSDEAYFALNREAARSGLVDVIDIELFNDEAQIRALVDDAHAAGVKVLMSNHDFHKTPAQEDII
YRLRRMQDLGADLPKIAVMPQSPQDVLTLLAATLTMKEKYATRPLITMSMGKSGGVSRVTGRLFGSAMTFGTVGQASAPG
QIAIAKLREVMDILS

Sequences:

>Translated_255_residues
MDTYMTNAVTVKNITFQEGETLICVPLIGKTLDEILGNAHGLVDAGADIIEWRVDHFAQVREMAQVMAALAEIRGALKAL
PLLFTFRSKKEGGETELSDEAYFALNREAARSGLVDVIDIELFNDEAQIRALVDDAHAAGVKVLMSNHDFHKTPAQEDII
YRLRRMQDLGADLPKIAVMPQSPQDVLTLLAATLTMKEKYATRPLITMSMGKSGGVSRVTGRLFGSAMTFGTVGQASAPG
QIAIAKLREVMDILS
>Mature_255_residues
MDTYMTNAVTVKNITFQEGETLICVPLIGKTLDEILGNAHGLVDAGADIIEWRVDHFAQVREMAQVMAALAEIRGALKAL
PLLFTFRSKKEGGETELSDEAYFALNREAARSGLVDVIDIELFNDEAQIRALVDDAHAAGVKVLMSNHDFHKTPAQEDII
YRLRRMQDLGADLPKIAVMPQSPQDVLTLLAATLTMKEKYATRPLITMSMGKSGGVSRVTGRLFGSAMTFGTVGQASAPG
QIAIAKLREVMDILS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family [H]

Homologues:

Organism=Escherichia coli, GI1787984, Length=246, Percent_Identity=56.5040650406504, Blast_Score=276, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6320332, Length=257, Percent_Identity=25.2918287937743, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018508
- InterPro:   IPR013785
- InterPro:   IPR001381 [H]

Pfam domain/function: PF01487 DHquinase_I [H]

EC number: =4.2.1.10 [H]

Molecular weight: Translated: 27763; Mature: 27763

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTYMTNAVTVKNITFQEGETLICVPLIGKTLDEILGNAHGLVDAGADIIEWRVDHFAQV
CCCCCCCEEEEEEEEECCCCEEEEHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHH
REMAQVMAALAEIRGALKALPLLFTFRSKKEGGETELSDEAYFALNREAARSGLVDVIDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEECHHHHHCCCEEEEEE
ELFNDEAQIRALVDDAHAAGVKVLMSNHDFHKTPAQEDIIYRLRRMQDLGADLPKIAVMP
EEECCHHHHHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECC
QSPQDVLTLLAATLTMKEKYATRPLITMSMGKSGGVSRVTGRLFGSAMTFGTVGQASAPG
CCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
QIAIAKLREVMDILS
HHHHHHHHHHHHHHC
>Mature Secondary Structure
MDTYMTNAVTVKNITFQEGETLICVPLIGKTLDEILGNAHGLVDAGADIIEWRVDHFAQV
CCCCCCCEEEEEEEEECCCCEEEEHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHH
REMAQVMAALAEIRGALKALPLLFTFRSKKEGGETELSDEAYFALNREAARSGLVDVIDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEECHHHHHCCCEEEEEE
ELFNDEAQIRALVDDAHAAGVKVLMSNHDFHKTPAQEDIIYRLRRMQDLGADLPKIAVMP
EEECCHHHHHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEECC
QSPQDVLTLLAATLTMKEKYATRPLITMSMGKSGGVSRVTGRLFGSAMTFGTVGQASAPG
CCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
QIAIAKLREVMDILS
HHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA