BacMap

Definition	Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome.
Accession	NC_012731
Length	5,248,520

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The map label for this gene is gudP [H]

Identifier: 238893047

GI number: 238893047

Start: 868086

End: 869396

Strand: Reverse

Name: gudP [H]

Synonym: KP1_0884

Alternate gene names: 238893047

Gene position: 869396-868086 (Counterclockwise)

Preceding gene: 238893049

Following gene: 238893044

Centisome position: 16.56

GC content: 52.02

Gene sequence:

>1311_bases
ATGAGTATGTCAAACTCTCAGGAAGTCCTCACTTCCACATCGGGGGCGAAAAAAAGAAGCCGCGTACGGATAGTTATTCT
GCTGCTACTCTCCGTCGGAACGATGATCAATTATCTCGACCGTACCATCCTGGGTATTGTAGCGCCACAGTTAAGCAAAG
AAATCCATATCGATCCGGCGATGATGGGTATCATCTTCTCCGCCTTCGCCTGGACTTATGCGCTGGCGCAGATCCCCGGC
GGGATGTTTTTAGACCGCTTTGGCAACAAAGTGACCTATGCCCTGTCAGTTTTCTTCTGGTCGCTGTTTACCCTGCTGCA
AAGTTTCACCCTCGGCCTAAAATCCCTGCTGCTTCTGCGCCTGGGACTCGGCGTCAGCGAAGCGCCCTGCTTTCCGGCCA
ACAGCCGCATCGTCAGCACCTGGTTCCCTCAGCATGAGCGCGCGCGGGCAACGGCAACATATACAGTTGGTGAATATATA
GGGCTGGCCGCTTTCTCGCCGCTGTTATTTTTAATTCTCGAACATCATGGCTGGAGAACGCTTTTTTTCCTCACCGGCGG
ATTAGGTATTTTATTTACTTTAGTGTGGTGGCGTTTTTATCATGAACCGCATGAATCGCACACGGCTAATCAAGCGGAGC
TGGAGTATATCGGCGCAAACAGCATTAACAATAAAATCCAGAACGTTCCATTTAACTGGCGTGACGCCAGACGCCTGCTG
GGCTGTCGCCAGATCCTCGGCGCCAGCCTGGGTCAGTTCGCCGGCAACACCACACTGGTCTTTTTCCTGACGTGGTTTCC
CAGCTACCTCGCCAACGAGCGCCATCTTCCATGGCTGCACGTCGGCTTCTTCGCCACCTGGCCCTTCCTTGCCGCCGCGA
TTGGCATCCTCTTCGGCGGCTGGATCTCCGACCGGTTGTTGAAGCGAACCGGCTCCGTCAACATCAGTCGAAAGTTACCA
ATAATTTCCGGTTTATTGCTGTCCAGCTGTATTATCGCGGCGAATTGGGTAAGCGCCAATAGCACCGTAATTATTATCAT
GTCGGTGGCTTTTTTTGGCCAGGGGATGGTCGGTCTGGGCTGGACCTTAATTTCTGATATTACCCCGGAAAATATGGCAG
GCCTCACCGGCGGCATATTTAATTTCTGTGCCAATATGGCCTCGATTATCGCACCACTGATAATTGGTGTGATTATTTCC
GCCACGGGTAATTTCTTTTACGCGCTGATCTACGTCGGCCTGACGGCGCTGATTGGGGTGATTGCCTACATTTTTATCAT
CGGCGACATTAAGCGTATCGAACTCAAGTAG

Upstream 100 bases:

>100_bases
ACAAGGCATTGCTATTCATAGATACTACCTATAGCTCCTTGAGATATTTTTGCATATTAGAATATATGCAAAAATATTTT
AAACTTTAAAGGAACTCGCT

Downstream 100 bases:

>100_bases
GCCTGGTCGCCCCGGCGATGCCGGGGCGAGTAGTCAGATATCCTTCACCTTGCTGGTCAAAAACAGCGTCACCAGCGAAA
TGGCCGCGATCGTCCAGTAG

Product: permease of the major facilitator superfamily

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSMSNSQEVLTSTSGAKKRSRVRIVILLLLSVGTMINYLDRTILGIVAPQLSKEIHIDPAMMGIIFSAFAWTYALAQIPG
GMFLDRFGNKVTYALSVFFWSLFTLLQSFTLGLKSLLLLRLGLGVSEAPCFPANSRIVSTWFPQHERARATATYTVGEYI
GLAAFSPLLFLILEHHGWRTLFFLTGGLGILFTLVWWRFYHEPHESHTANQAELEYIGANSINNKIQNVPFNWRDARRLL
GCRQILGASLGQFAGNTTLVFFLTWFPSYLANERHLPWLHVGFFATWPFLAAAIGILFGGWISDRLLKRTGSVNISRKLP
IISGLLLSSCIIAANWVSANSTVIIIMSVAFFGQGMVGLGWTLISDITPENMAGLTGGIFNFCANMASIIAPLIIGVIIS
ATGNFFYALIYVGLTALIGVIAYIFIIGDIKRIELK

Sequences:

>Translated_436_residues
MSMSNSQEVLTSTSGAKKRSRVRIVILLLLSVGTMINYLDRTILGIVAPQLSKEIHIDPAMMGIIFSAFAWTYALAQIPG
GMFLDRFGNKVTYALSVFFWSLFTLLQSFTLGLKSLLLLRLGLGVSEAPCFPANSRIVSTWFPQHERARATATYTVGEYI
GLAAFSPLLFLILEHHGWRTLFFLTGGLGILFTLVWWRFYHEPHESHTANQAELEYIGANSINNKIQNVPFNWRDARRLL
GCRQILGASLGQFAGNTTLVFFLTWFPSYLANERHLPWLHVGFFATWPFLAAAIGILFGGWISDRLLKRTGSVNISRKLP
IISGLLLSSCIIAANWVSANSTVIIIMSVAFFGQGMVGLGWTLISDITPENMAGLTGGIFNFCANMASIIAPLIIGVIIS
ATGNFFYALIYVGLTALIGVIAYIFIIGDIKRIELK
>Mature_435_residues
SMSNSQEVLTSTSGAKKRSRVRIVILLLLSVGTMINYLDRTILGIVAPQLSKEIHIDPAMMGIIFSAFAWTYALAQIPGG
MFLDRFGNKVTYALSVFFWSLFTLLQSFTLGLKSLLLLRLGLGVSEAPCFPANSRIVSTWFPQHERARATATYTVGEYIG
LAAFSPLLFLILEHHGWRTLFFLTGGLGILFTLVWWRFYHEPHESHTANQAELEYIGANSINNKIQNVPFNWRDARRLLG
CRQILGASLGQFAGNTTLVFFLTWFPSYLANERHLPWLHVGFFATWPFLAAAIGILFGGWISDRLLKRTGSVNISRKLPI
ISGLLLSSCIIAANWVSANSTVIIIMSVAFFGQGMVGLGWTLISDITPENMAGLTGGIFNFCANMASIIAPLIIGVIISA
TGNFFYALIYVGLTALIGVIAYIFIIGDIKRIELK

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9945322, Length=389, Percent_Identity=24.6786632390745, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI21322234, Length=404, Percent_Identity=23.019801980198, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI154350196, Length=406, Percent_Identity=24.1379310344828, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI9966811, Length=387, Percent_Identity=24.5478036175711, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI148743791, Length=390, Percent_Identity=25.3846153846154, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI6912666, Length=355, Percent_Identity=24.7887323943662, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI223718438, Length=398, Percent_Identity=21.8592964824121, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI148728191, Length=330, Percent_Identity=25.4545454545455, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4885441, Length=378, Percent_Identity=24.8677248677249, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI5031955, Length=255, Percent_Identity=24.7058823529412, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI154800443, Length=347, Percent_Identity=24.207492795389, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789152, Length=439, Percent_Identity=43.7357630979499, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI87082320, Length=425, Percent_Identity=42.8235294117647, Blast_Score=363, Evalue=1e-102,
Organism=Escherichia coli, GI1789515, Length=442, Percent_Identity=41.4027149321267, Blast_Score=346, Evalue=2e-96,
Organism=Escherichia coli, GI2367379, Length=430, Percent_Identity=30.6976744186047, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI2367193, Length=390, Percent_Identity=26.1538461538462, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87082071, Length=304, Percent_Identity=23.6842105263158, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115533554, Length=381, Percent_Identity=23.6220472440945, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115533556, Length=381, Percent_Identity=23.6220472440945, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI193205400, Length=319, Percent_Identity=24.1379310344828, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17535049, Length=429, Percent_Identity=22.8438228438228, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25141316, Length=438, Percent_Identity=24.2009132420091, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25141341, Length=327, Percent_Identity=25.6880733944954, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI25141318, Length=327, Percent_Identity=25.9938837920489, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17552542, Length=359, Percent_Identity=24.2339832869081, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560030, Length=376, Percent_Identity=24.7340425531915, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17554148, Length=309, Percent_Identity=22.9773462783171, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32565914, Length=355, Percent_Identity=23.0985915492958, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI86561091, Length=308, Percent_Identity=25.6493506493506, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32565916, Length=237, Percent_Identity=22.7848101265823, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560966, Length=336, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193208223, Length=421, Percent_Identity=22.8028503562945, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17554962, Length=325, Percent_Identity=21.5384615384615, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71997452, Length=401, Percent_Identity=19.9501246882793, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71991448, Length=355, Percent_Identity=24.5070422535211, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71991453, Length=355, Percent_Identity=24.5070422535211, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI28573299, Length=389, Percent_Identity=28.2776349614396, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24583789, Length=388, Percent_Identity=23.1958762886598, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573708, Length=366, Percent_Identity=24.5901639344262, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573707, Length=366, Percent_Identity=24.5901639344262, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19922400, Length=354, Percent_Identity=25.4237288135593, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24654215, Length=354, Percent_Identity=25.4237288135593, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24584153, Length=381, Percent_Identity=21.7847769028871, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24658658, Length=437, Percent_Identity=23.7986270022883, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24648416, Length=424, Percent_Identity=22.1698113207547, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI21356189, Length=424, Percent_Identity=22.1698113207547, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24641682, Length=387, Percent_Identity=26.0981912144703, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24655271, Length=415, Percent_Identity=24.578313253012, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24655255, Length=389, Percent_Identity=25.1928020565553, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45550460, Length=389, Percent_Identity=25.1928020565553, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI20130135, Length=415, Percent_Identity=24.578313253012, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI62484226, Length=396, Percent_Identity=25.2525252525253, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221474708, Length=168, Percent_Identity=29.7619047619048, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24639764, Length=440, Percent_Identity=24.7727272727273, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920686, Length=408, Percent_Identity=24.5098039215686, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24653727, Length=360, Percent_Identity=23.6111111111111, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI20129235, Length=456, Percent_Identity=23.0263157894737, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24658689, Length=380, Percent_Identity=25.5263157894737, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24658674, Length=358, Percent_Identity=24.5810055865922, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45550495, Length=362, Percent_Identity=24.3093922651934, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45552797, Length=350, Percent_Identity=25.4285714285714, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24658666, Length=405, Percent_Identity=22.4691358024691, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48177; Mature: 48046

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSNSQEVLTSTSGAKKRSRVRIVILLLLSVGTMINYLDRTILGIVAPQLSKEIHIDPA
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
MMGIIFSAFAWTYALAQIPGGMFLDRFGNKVTYALSVFFWSLFTLLQSFTLGLKSLLLLR
HHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLGVSEAPCFPANSRIVSTWFPQHERARATATYTVGEYIGLAAFSPLLFLILEHHGWRT
HCCCCCCCCCCCCCCCEEEECCCCCHHCHHHEEEEHHHHHHHHHHHHHHHHHHHCCCCEE
LFFLTGGLGILFTLVWWRFYHEPHESHTANQAELEYIGANSINNKIQNVPFNWRDARRLL
EEEHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCHHHHHHHH
GCRQILGASLGQFAGNTTLVFFLTWFPSYLANERHLPWLHVGFFATWPFLAAAIGILFGG
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHH
WISDRLLKRTGSVNISRKLPIISGLLLSSCIIAANWVSANSTVIIIMSVAFFGQGMVGLG
HHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHEECCCCEEEEEEEHHHHCCCHHHHH
WTLISDITPENMAGLTGGIFNFCANMASIIAPLIIGVIISATGNFFYALIYVGLTALIGV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IAYIFIIGDIKRIELK
HHHHHHHCCCEEEECC
>Mature Secondary Structure 
SMSNSQEVLTSTSGAKKRSRVRIVILLLLSVGTMINYLDRTILGIVAPQLSKEIHIDPA
CCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
MMGIIFSAFAWTYALAQIPGGMFLDRFGNKVTYALSVFFWSLFTLLQSFTLGLKSLLLLR
HHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLGVSEAPCFPANSRIVSTWFPQHERARATATYTVGEYIGLAAFSPLLFLILEHHGWRT
HCCCCCCCCCCCCCCCEEEECCCCCHHCHHHEEEEHHHHHHHHHHHHHHHHHHHCCCCEE
LFFLTGGLGILFTLVWWRFYHEPHESHTANQAELEYIGANSINNKIQNVPFNWRDARRLL
EEEHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHCCCCCHHHHHHHH
GCRQILGASLGQFAGNTTLVFFLTWFPSYLANERHLPWLHVGFFATWPFLAAAIGILFGG
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHH
WISDRLLKRTGSVNISRKLPIISGLLLSSCIIAANWVSANSTVIIIMSVAFFGQGMVGLG
HHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHEECCCCEEEEEEEHHHHCCCHHHHH
WTLISDITPENMAGLTGGIFNFCANMASIIAPLIIGVIISATGNFFYALIYVGLTALIGV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
IAYIFIIGDIKRIELK
HHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9772162; 10762278 [H]