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The map label for this gene is yabF [C]

Identifier: 238892886

GI number: 238892886

Start: 698086

End: 698868

Strand: Reverse

Name: yabF [C]

Synonym: KP1_0706

Alternate gene names: 238892886

Gene position: 698868-698086 (Counterclockwise)

Preceding gene: 238892889

Following gene: 238892881

Centisome position: 13.32

GC content: 62.45

Gene sequence:

>783_bases
ATGAAAGTACTGCTGATTTACGCCCATCCGGAACCGCGCTCGCTCAATGGCGCGCTGAAAAATTTCGCCATCCGCCATCT
GCAGCAGGCCGGGCATGAAGTGCAGGTTTCCGATCTCTACGCTATGCGCTGGAAGGCCGGGTATGACGCCGACGATAGCG
GCGCCCCGCCGGTCGGCGAGTTCTGGCGGCCGACCCTCGATTCCAAACAGGCCTTTGCCCAGGGCACCCAAAGTGCGGAT
ATCGTAGCCGAGCAGGAAAAGCTGCTGTGGGCCGATACGGTGATTTTCCAGTTCCCGCTATGGTGGTTCTCGATGCCCGC
CATCATGAAGGGCTGGATCGACAGGGTGTACGCCTGGGGCTTTGCCTATGGCGTCGGCGAGCACAGCGACCGCCACTGGG
GCGATCGCTACGGGGAAGGCACTTTCGTCGGCAAGCGGGCGATGCTGATCGTCACCGCCGGCGGCTGGGCGGAACACTAT
TCACCACGCGGGATCAATGGCCCCATCGACGACATCCTGTTCCCCATTCAGCACGGTATGCTGTTCTACCCCGGCTTTGA
GGTGCTTCCGCCGCTGGTGTTCTACCGCACGGATAAAACCGATGCCGGGCAGTTCGCCGATCAGTGCGCCGCCCTGGCCG
AGCGGCTGGACACGCTGTGGCAAACCGAGCCCATTCCATTCCGCCGCCAGAATCATGGCGATTATCTGATCCCGTCGCTG
ACGCTGCGCCCGGAGCTGGCGCCAGGGCAAAGCGGCCTGGCGGTGCATTTGCGTAGCGAATAA

Upstream 100 bases:

>100_bases
TGTAAATTAATCACGACTATACCGGTAATTTAAGTAATTAATTTCTACTATAGCGTCAGCTTTCCTACTCTGCAGCTCTC
CATACGCCAGAGGTGATATT

Downstream 100 bases:

>100_bases
CTGGCTATCCCGTCTTCGCCCCCGAGGACGGGTCATTTACCCGGCTCTCTCCAGTCCCAGCATGCCTCGCGCCTGGATAA
AGCACAGCAGCAATACGCCC

Product: NAD(P)H quinone oxidoreductase

Products: NAD(P); reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MKVLLIYAHPEPRSLNGALKNFAIRHLQQAGHEVQVSDLYAMRWKAGYDADDSGAPPVGEFWRPTLDSKQAFAQGTQSAD
IVAEQEKLLWADTVIFQFPLWWFSMPAIMKGWIDRVYAWGFAYGVGEHSDRHWGDRYGEGTFVGKRAMLIVTAGGWAEHY
SPRGINGPIDDILFPIQHGMLFYPGFEVLPPLVFYRTDKTDAGQFADQCAALAERLDTLWQTEPIPFRRQNHGDYLIPSL
TLRPELAPGQSGLAVHLRSE

Sequences:

>Translated_260_residues
MKVLLIYAHPEPRSLNGALKNFAIRHLQQAGHEVQVSDLYAMRWKAGYDADDSGAPPVGEFWRPTLDSKQAFAQGTQSAD
IVAEQEKLLWADTVIFQFPLWWFSMPAIMKGWIDRVYAWGFAYGVGEHSDRHWGDRYGEGTFVGKRAMLIVTAGGWAEHY
SPRGINGPIDDILFPIQHGMLFYPGFEVLPPLVFYRTDKTDAGQFADQCAALAERLDTLWQTEPIPFRRQNHGDYLIPSL
TLRPELAPGQSGLAVHLRSE
>Mature_260_residues
MKVLLIYAHPEPRSLNGALKNFAIRHLQQAGHEVQVSDLYAMRWKAGYDADDSGAPPVGEFWRPTLDSKQAFAQGTQSAD
IVAEQEKLLWADTVIFQFPLWWFSMPAIMKGWIDRVYAWGFAYGVGEHSDRHWGDRYGEGTFVGKRAMLIVTAGGWAEHY
SPRGINGPIDDILFPIQHGMLFYPGFEVLPPLVFYRTDKTDAGQFADQCAALAERLDTLWQTEPIPFRRQNHGDYLIPSL
TLRPELAPGQSGLAVHLRSE

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=226, Percent_Identity=42.9203539823009, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI4505415, Length=227, Percent_Identity=39.2070484581498, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI70995396, Length=227, Percent_Identity=31.7180616740088, Blast_Score=90, Evalue=2e-18,
Organism=Escherichia coli, GI1786231, Length=139, Percent_Identity=32.3741007194245, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.- [C]

Molecular weight: Translated: 29361; Mature: 29361

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLLIYAHPEPRSLNGALKNFAIRHLQQAGHEVQVSDLYAMRWKAGYDADDSGAPPVGE
CEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEHHEEEEHCCCCCCCCCCCCCCCHH
FWRPTLDSKQAFAQGTQSADIVAEQEKLLWADTVIFQFPLWWFSMPAIMKGWIDRVYAWG
HHCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAYGVGEHSDRHWGDRYGEGTFVGKRAMLIVTAGGWAEHYSPRGINGPIDDILFPIQHGM
HHHCCCCCCCCCCCCCCCCCEEECCEEEEEEECCCHHHHCCCCCCCCCHHHHHHHHHCCE
LFYPGFEVLPPLVFYRTDKTDAGQFADQCAALAERLDTLWQTEPIPFRRQNHGDYLIPSL
EEECCHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCE
TLRPELAPGQSGLAVHLRSE
EECCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MKVLLIYAHPEPRSLNGALKNFAIRHLQQAGHEVQVSDLYAMRWKAGYDADDSGAPPVGE
CEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEHHEEEEHCCCCCCCCCCCCCCCHH
FWRPTLDSKQAFAQGTQSADIVAEQEKLLWADTVIFQFPLWWFSMPAIMKGWIDRVYAWG
HHCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAYGVGEHSDRHWGDRYGEGTFVGKRAMLIVTAGGWAEHYSPRGINGPIDDILFPIQHGM
HHHCCCCCCCCCCCCCCCCCEEECCEEEEEEECCCHHHHCCCCCCCCCHHHHHHHHHCCE
LFYPGFEVLPPLVFYRTDKTDAGQFADQCAALAERLDTLWQTEPIPFRRQNHGDYLIPSL
EEECCHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCE
TLRPELAPGQSGLAVHLRSE
EECCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NAD(P)H2; acceptor [C]

Specific reaction: NAD(P)H2 + acceptor = NAD(P) + reduced acceptor [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]