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The map label for this gene is trpS [H]

Identifier: 238892881

GI number: 238892881

Start: 692102

End: 693109

Strand: Reverse

Name: trpS [H]

Synonym: KP1_0701

Alternate gene names: 238892881

Gene position: 693109-692102 (Counterclockwise)

Preceding gene: 238892886

Following gene: 238892880

Centisome position: 13.21

GC content: 60.32

Gene sequence:

>1008_bases
ATGAACCATCCACAAACCATCCTCACCGGCGACCGCCCGACCGGCCAACTTCATCTTGGCCACTACGTCGGCTCGCTGCG
CCAGCGCGTCGCGCTGCAGCATAACCACCAGCAATTTATCCTGATCGCCGACCTGCAAGGGCTCACGGACAACGGCAGCA
ATCCGCAAAAAATCAGCCACCATATCCTCGAAGTCATGGCCGATTATCTGGCCGTCGGCATCGACCCCAGGCTCACCACT
ATTTGCCTGCAGTCCGCCCTGCCGGCGCTGGCGGAGCTCAGCGCGTTGTATATGAATATCGTCACCGTCGCCCGCGTAGA
ACGTAATCCGACGGTCAAAAATGAGATTGCCCAGAAGGGATTCGCCCGCTCGCTGCCGGTGGGTTTTCTCGCCTATCCGA
TTAGCCAGGCGGCCGATATCACCGCGTTCAAGGCCGAACTGGTGCCGGTGGGCGACGATCAGCTACCGATGATTGAGCAG
ACCAACGAGATCGTCCACAAGATGAATAGCCTCACCGGCGAGCCGGTGCTGCGCCACTGCAAGGCGCTACTCAGCGAAGT
GAGTCGCCTGCCGGGCGTCGACGGTAATGCCAAAATGTCGAAATCGCTGGGCAATACGCTGACGTTATCGGCCAGTGAAG
AGGAGATCCACCGCGCGGTCAGCGCGATGTATACCGACCCGACGCACCTGAGAGTCAGCGATCCGGGGCATGTCGAGGGC
AACGTGGTGTTTACCTATCTCGATGCATTCCACAGCGATAAGGCGCGGGTGGCAGAGATGAAAGCCCACTATCAGCGCGG
CGGGCTGGGCGATCGCCAGTGTAAGAATGAGCTGGAGACCTGCTTGCAGACGCTACTGGCGCCGATCCGCGAACGCAGGG
CCACTTTTATTCAGGATAAAGGGATGCTGCTGGAGCTGCTGCGCCAGGGCAGCGAACGCGCCCACCACCTCACACAGCAG
ACGCTGCATGAGGTGAAGCGTGGGCTGGGTCTGCCGGTGCTGTTCTGA

Upstream 100 bases:

>100_bases
CAGGCGGCACGATACACGTTTCCATTTTCAAAGCCGCCGGAAGGCGGCTTTGGTGTTTTCAGGACGTCTTTCGGCTGAAC
AGTCTGATAAGGAGTCCCTG

Downstream 100 bases:

>100_bases
GATGGTGAAATACTCCCTGTGCGGATAATTTTGTTAACACGCCGACAAGACCCTGTCTTTCGTATGGACAATATCGCCCC
GGCTGTTACTATCGCGTTAA

Product: tryptophanyl-tRNA synthetase II

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNHPQTILTGDRPTGQLHLGHYVGSLRQRVALQHNHQQFILIADLQGLTDNGSNPQKISHHILEVMADYLAVGIDPRLTT
ICLQSALPALAELSALYMNIVTVARVERNPTVKNEIAQKGFARSLPVGFLAYPISQAADITAFKAELVPVGDDQLPMIEQ
TNEIVHKMNSLTGEPVLRHCKALLSEVSRLPGVDGNAKMSKSLGNTLTLSASEEEIHRAVSAMYTDPTHLRVSDPGHVEG
NVVFTYLDAFHSDKARVAEMKAHYQRGGLGDRQCKNELETCLQTLLAPIRERRATFIQDKGMLLELLRQGSERAHHLTQQ
TLHEVKRGLGLPVLF

Sequences:

>Translated_335_residues
MNHPQTILTGDRPTGQLHLGHYVGSLRQRVALQHNHQQFILIADLQGLTDNGSNPQKISHHILEVMADYLAVGIDPRLTT
ICLQSALPALAELSALYMNIVTVARVERNPTVKNEIAQKGFARSLPVGFLAYPISQAADITAFKAELVPVGDDQLPMIEQ
TNEIVHKMNSLTGEPVLRHCKALLSEVSRLPGVDGNAKMSKSLGNTLTLSASEEEIHRAVSAMYTDPTHLRVSDPGHVEG
NVVFTYLDAFHSDKARVAEMKAHYQRGGLGDRQCKNELETCLQTLLAPIRERRATFIQDKGMLLELLRQGSERAHHLTQQ
TLHEVKRGLGLPVLF
>Mature_335_residues
MNHPQTILTGDRPTGQLHLGHYVGSLRQRVALQHNHQQFILIADLQGLTDNGSNPQKISHHILEVMADYLAVGIDPRLTT
ICLQSALPALAELSALYMNIVTVARVERNPTVKNEIAQKGFARSLPVGFLAYPISQAADITAFKAELVPVGDDQLPMIEQ
TNEIVHKMNSLTGEPVLRHCKALLSEVSRLPGVDGNAKMSKSLGNTLTLSASEEEIHRAVSAMYTDPTHLRVSDPGHVEG
NVVFTYLDAFHSDKARVAEMKAHYQRGGLGDRQCKNELETCLQTLLAPIRERRATFIQDKGMLLELLRQGSERAHHLTQQ
TLHEVKRGLGLPVLF

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=332, Percent_Identity=28.3132530120482, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI41352700, Length=169, Percent_Identity=31.9526627218935, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1789786, Length=342, Percent_Identity=26.9005847953216, Blast_Score=118, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI71982800, Length=341, Percent_Identity=26.6862170087977, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71982793, Length=341, Percent_Identity=26.6862170087977, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320474, Length=243, Percent_Identity=27.9835390946502, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24666151, Length=339, Percent_Identity=31.2684365781711, Blast_Score=132, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37024; Mature: 37024

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHPQTILTGDRPTGQLHLGHYVGSLRQRVALQHNHQQFILIADLQGLTDNGSNPQKISH
CCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHH
HILEVMADYLAVGIDPRLTTICLQSALPALAELSALYMNIVTVARVERNPTVKNEIAQKG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
FARSLPVGFLAYPISQAADITAFKAELVPVGDDQLPMIEQTNEIVHKMNSLTGEPVLRHC
CHHCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
KALLSEVSRLPGVDGNAKMSKSLGNTLTLSASEEEIHRAVSAMYTDPTHLRVSDPGHVEG
HHHHHHHHHCCCCCCCCHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCC
NVVFTYLDAFHSDKARVAEMKAHYQRGGLGDRQCKNELETCLQTLLAPIRERRATFIQDK
CEEEEEHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GMLLELLRQGSERAHHLTQQTLHEVKRGLGLPVLF
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNHPQTILTGDRPTGQLHLGHYVGSLRQRVALQHNHQQFILIADLQGLTDNGSNPQKISH
CCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHH
HILEVMADYLAVGIDPRLTTICLQSALPALAELSALYMNIVTVARVERNPTVKNEIAQKG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
FARSLPVGFLAYPISQAADITAFKAELVPVGDDQLPMIEQTNEIVHKMNSLTGEPVLRHC
CHHCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
KALLSEVSRLPGVDGNAKMSKSLGNTLTLSASEEEIHRAVSAMYTDPTHLRVSDPGHVEG
HHHHHHHHHCCCCCCCCHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCC
NVVFTYLDAFHSDKARVAEMKAHYQRGGLGDRQCKNELETCLQTLLAPIRERRATFIQDK
CEEEEEHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GMLLELLRQGSERAHHLTQQTLHEVKRGLGLPVLF
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA