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The map label for this gene is ompR [H]

Identifier: 238892572

GI number: 238892572

Start: 359142

End: 359870

Strand: Direct

Name: ompR [H]

Synonym: KP1_0348

Alternate gene names: 238892572

Gene position: 359142-359870 (Clockwise)

Preceding gene: 238892569

Following gene: 238892577

Centisome position: 6.84

GC content: 62.83

Gene sequence:

>729_bases
ATGAAACCAGTCATTTTAGTGGTGGATGATGACAGGGCAATGGGCGAGCTGCTCAGCGATGTGCTCGGCGCGCACGCGTT
TGAAGTGCTTGTCAGCCAGACCGGCAACGACGCGCTGACGACGGTGGCGCAGCGGGCGGATATCGCGCTGGTCTTACTGG
ATATGATCCTGCCGGATACCCATGGCCTGCAGGTGCTCCAGCAGCTGCAGCGCACGCGGCCTGAGCTGCCGGTGGTGATG
CTCTCCGGTCTGGGCAGTGAGTCTGATGTGGTGGTGGGCCTGGAGATGGGCGCCGATGATTACATCGCCAAACCGTTCAG
CTCGCGGGTGGTGGTCGCCCGGGTGAAAGCGGTACTGCGACGCAGCGGGGCGCTGGCCGGCGAGGCGTCGGGCGCCGGTG
CTGGCCTGACGTTTAACGGCTGGCGGCTGGATACCACGCGCTGTGAACTGTATAACCCGCAGCAGCAGGCGATCCCGCTG
ACCCAGGGAGAATATGGCCTGCTGCTGGCGCTGGCGCAGAACGCGCGCCGGGTATTGAATCGCGAACAGCTGCTGGCGCT
GACTCATAATGAAAGCACCGAGGTATTCGACCGGACCATCGATGTGCTGATCATGCGCCTGCGGCGCAAAATTGAGCTCA
ACCCGCATCAGCCGACGTTGATTAAAACCCTGCGCGGTCTGGGCTATGTCTTTTCCGCCGACGTGACCCACAGCGAGAAG
GCGGCGTAG

Upstream 100 bases:

>100_bases
GTGACGGCGCTTGAAAAAATGTCACCGGGAGAGGAATTTGTCGGCGCAGGCTTGCAGAATCGATCAGACTGACACTAATT
CCCGGCGGGCAGAGGCAAAA

Downstream 100 bases:

>100_bases
GGCGGGAAGCTGTCTAACCGGCCCGCCCGGCGCTGGAGTATCTAACCATTCTGCAATTGTATAAACGCCTGCAGCTCAGG
GAGCGTTTTGGCGCCGTCGA

Product: putative response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MKPVILVVDDDRAMGELLSDVLGAHAFEVLVSQTGNDALTTVAQRADIALVLLDMILPDTHGLQVLQQLQRTRPELPVVM
LSGLGSESDVVVGLEMGADDYIAKPFSSRVVVARVKAVLRRSGALAGEASGAGAGLTFNGWRLDTTRCELYNPQQQAIPL
TQGEYGLLLALAQNARRVLNREQLLALTHNESTEVFDRTIDVLIMRLRRKIELNPHQPTLIKTLRGLGYVFSADVTHSEK
AA

Sequences:

>Translated_242_residues
MKPVILVVDDDRAMGELLSDVLGAHAFEVLVSQTGNDALTTVAQRADIALVLLDMILPDTHGLQVLQQLQRTRPELPVVM
LSGLGSESDVVVGLEMGADDYIAKPFSSRVVVARVKAVLRRSGALAGEASGAGAGLTFNGWRLDTTRCELYNPQQQAIPL
TQGEYGLLLALAQNARRVLNREQLLALTHNESTEVFDRTIDVLIMRLRRKIELNPHQPTLIKTLRGLGYVFSADVTHSEK
AA
>Mature_242_residues
MKPVILVVDDDRAMGELLSDVLGAHAFEVLVSQTGNDALTTVAQRADIALVLLDMILPDTHGLQVLQQLQRTRPELPVVM
LSGLGSESDVVVGLEMGADDYIAKPFSSRVVVARVKAVLRRSGALAGEASGAGAGLTFNGWRLDTTRCELYNPQQQAIPL
TQGEYGLLLALAQNARRVLNREQLLALTHNESTEVFDRTIDVLIMRLRRKIELNPHQPTLIKTLRGLGYVFSADVTHSEK
AA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=38.5281385281385, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=31.9148936170213, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=38.8888888888889, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=36.480686695279, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=37.5545851528384, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=33.6206896551724, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=34.4978165938865, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=34.6153846153846, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=32.4561403508772, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=32.4786324786325, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1787375, Length=186, Percent_Identity=34.4086021505376, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=29.9559471365639, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1790552, Length=239, Percent_Identity=31.7991631799163, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=29.4372294372294, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26372; Mature: 26372

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVILVVDDDRAMGELLSDVLGAHAFEVLVSQTGNDALTTVAQRADIALVLLDMILPDT
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
HGLQVLQQLQRTRPELPVVMLSGLGSESDVVVGLEMGADDYIAKPFSSRVVVARVKAVLR
HHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEECCCHHHCCCCCCCHHHHHHHHHHH
RSGALAGEASGAGAGLTFNGWRLDTTRCELYNPQQQAIPLTQGEYGLLLALAQNARRVLN
HCCCCCCCCCCCCCCEEECCEEEECCEEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHC
REQLLALTHNESTEVFDRTIDVLIMRLRRKIELNPHQPTLIKTLRGLGYVFSADVTHSEK
HHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEECCCCCCCC
AA
CC
>Mature Secondary Structure
MKPVILVVDDDRAMGELLSDVLGAHAFEVLVSQTGNDALTTVAQRADIALVLLDMILPDT
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
HGLQVLQQLQRTRPELPVVMLSGLGSESDVVVGLEMGADDYIAKPFSSRVVVARVKAVLR
HHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEECCCHHHCCCCCCCHHHHHHHHHHH
RSGALAGEASGAGAGLTFNGWRLDTTRCELYNPQQQAIPLTQGEYGLLLALAQNARRVLN
HCCCCCCCCCCCCCCEEECCEEEECCEEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHC
REQLLALTHNESTEVFDRTIDVLIMRLRRKIELNPHQPTLIKTLRGLGYVFSADVTHSEK
HHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEECCCCCCCC
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]