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The map label for this gene is atoS [C]

Identifier: 238892577

GI number: 238892577

Start: 364661

End: 366946

Strand: Direct

Name: atoS [C]

Synonym: KP1_0354

Alternate gene names: 238892577

Gene position: 364661-366946 (Clockwise)

Preceding gene: 238892572

Following gene: 238892578

Centisome position: 6.95

GC content: 65.97

Gene sequence:

>2286_bases
ATGACCGCTCGCCGATACCCGTTTTTCACCAGCGCCCGTGGCCGCCTGCTCTCCTTTAATCTGCTGATGGTCGTGGTCAC
CCTGTTGGTCAGCGGCGTGGCGGTGTTCGGCTTTCATCACGCCAGCCAGCTGCAGGAGCAGGTGCAGCGCCAGACTCTCA
ACGACATGCGAGGCAGTATGGATCTGGCGCGGGACACGGCGAATGTCGCCACGGCGGCGGTGCGCCTGTCGCAGGTGGTG
GGGGCGCTGGAGTACAAAAGCGAAGCGGAACGGCTGCTGGCGACGCAGCAGGCGCTGAAGCACTCGCTGGCCCAGCTGGC
GGCGGCCCCGCTGGCGCAGCAGGAGCAGGCGCGGGTGGCCAATATTATTCGCCGCAGCAACGCGCTGCAGCAGAGCGTGG
CGGAGATGCTGGAGCGCGGCCAGCGCCGCCATCTGCAGCGCAATGCGCTGCTGAGTTCGCTTTACCAGAATCAGAGTAAC
CTGCGCCATCTCGCCGATCTTAACGATCGCGGCGGGGATAAGGCGATCGATCCGCGCCGGCTGGCCGAGATGGACCGGCT
GATCGTGGCTGCGATCCATACCGTCACGCCGCGGTCGATCGTCCTGCAACTCGACCAGCTGCGCGGCGCCCTGCCGACAC
GCAGCGCCGATCCCGCGCTGGCGTTTGTCCTCCCTGATGTGACCCGCGAACTGGCGACGCTGGCCCCGCTGTCGGCCCAG
CTGGAGGAGAGCGACCTGACGATCAGCTGGTACATGTATCACATCAAAGCGCTGGTCGCGTTGCTTAACGAAGATATCAA
TCAGTACGTGACCCGGGTGGCGGAAGCCTCAGAGCAGCGGGCGGCGCAGAGCCATCGGGAGCTGCGCTCCATCAGTATGT
TTATTCTGCTTTCCGCGCTGCTGGCGCTGGCGATCACCGGCTGCGCCGGGTGGTACATCTACCGTAATCTCGGCTCGAAC
CTGACCGCCATCTCGCGGGCGATGTCGCGGCTGGCTCAGGGAGAGCCGAACGTCTCGGTGCCGGCCCTGCAGCGGCGCGA
CGAGCTGGGGGAGCTGGCGCGGGCCTTTAACGTTTTCGCCCGCAATATGGCGTCGCTGGAGCACACCACCCGGCTGCTGA
AAGAGAAGACCAACCAGATGGAGATCGATCGGATTAAGCGCCAGGAGCTGGAGGAGGCGCTGCTGCATAGTCAGAAGATG
AAGGCCGTCGGCCAGCTGACCGGAGGTCTGGCGCATGACTTTAACAACCTGCTGGCGGTGATTATCGGCAGCCTTGAGCT
GGTGGAGCCGGATGCGCGCGATGCGCCGCGCCTCTCCAGGGCGCTGAAGGCGGCGGAGCGTGGGGCGCTTCTGACCCAGC
GGCTGCTGGCCTTTTCGCGCAAGCAGGCGCTGCATCCCCAGGCGGTGGCGATGGCGCCGCTACTGGAGAACCTCAGCGAG
CTGATGCGTCACTCCCTGCCGGCGACCTTAAGCCTGGAGATTGAGGCGCAGTCGCCGGCGTGGCCGGCATGGATAGACGT
TGGCCAGCTGGAAAACGCCCTGATCAATCTGGTGATGAACGCCCGCGACGCCATGGCGGGGCGCGACGGGGTCATCAAAA
TACGCACCTGGAATCAGCGGGTCACCCGCAGCAGCGGCCAGCGGCAGGATATGGTGGCCCTGGAGGTGATCGATCATGGC
AGCGGGATGTCGCAGGCGGTGAAAGCCCGGGTGTTTGAACCTTTCTTCACCACCAAAGCCACCGGCAGCGGCAGCGGCCT
GGGGCTGTCGATGGTGTATGGCTTTGTGCGCCAGTCTGGCGGCCGGGTGGCGCTGGAGAGCGCGCCGGGGCAGGGGACGA
CGGTGCGGCTGCAGCTGCCGCGAGCGTTGACCGAGGTTGAGAAGGAGGTGGCGCCAGCGGTGGACGAGCCGTCCCCGGCG
GGCGAGCGGCTGGCGCTGGTGCTGGAAGATGAAGAGGATGTCCGCCAGACGCTATGTGAACAGCTGCATCAGCTGGGCTG
GCTGACGCTGGAAACCGCCAGCGGTGAAGAGGCGCTGCAGCTGCTGGAGGCCTCGCCGGATATTGCCCTGCTGATTAGCG
ATCTGATGCTGCCCGGGGCCCTGAGCGGCGCCGATGTGATCCATACCGCCCGACGCCGCTTTCCGGCGCTGCCGGTGCTA
CTGATCAGCGGCCAGGATTTGCGTCCAGCGCAGAACCCGGCCCTGCCGGAGGTTGAGTGGCTGCGTAAGCCGTTTACCCG
AGCCCAGCTGGCGCAGGCGCTGAGCGCGGCGTACGCGAGGATTTGA

Upstream 100 bases:

>100_bases
TTTGTCATAGTGATAAATAGTTAACCGCGATCACAGTTACGCGGCGTCATTTTCTGCACCGTCACGCTTATCTGCCGACC
GATCCTTCACCGGAGTTGTT

Downstream 100 bases:

>100_bases
GATTCCTCCGCTACCCGGGTTTCATGCGGATGATTAAGGTAGCGGCAGGACTCTGATGAGATTGGCCCCGATGAAACGTT
ACGCAACCGCACTGCTCTTT

Product: putative histidine protein kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 761; Mature: 760

Protein sequence:

>761_residues
MTARRYPFFTSARGRLLSFNLLMVVVTLLVSGVAVFGFHHASQLQEQVQRQTLNDMRGSMDLARDTANVATAAVRLSQVV
GALEYKSEAERLLATQQALKHSLAQLAAAPLAQQEQARVANIIRRSNALQQSVAEMLERGQRRHLQRNALLSSLYQNQSN
LRHLADLNDRGGDKAIDPRRLAEMDRLIVAAIHTVTPRSIVLQLDQLRGALPTRSADPALAFVLPDVTRELATLAPLSAQ
LEESDLTISWYMYHIKALVALLNEDINQYVTRVAEASEQRAAQSHRELRSISMFILLSALLALAITGCAGWYIYRNLGSN
LTAISRAMSRLAQGEPNVSVPALQRRDELGELARAFNVFARNMASLEHTTRLLKEKTNQMEIDRIKRQELEEALLHSQKM
KAVGQLTGGLAHDFNNLLAVIIGSLELVEPDARDAPRLSRALKAAERGALLTQRLLAFSRKQALHPQAVAMAPLLENLSE
LMRHSLPATLSLEIEAQSPAWPAWIDVGQLENALINLVMNARDAMAGRDGVIKIRTWNQRVTRSSGQRQDMVALEVIDHG
SGMSQAVKARVFEPFFTTKATGSGSGLGLSMVYGFVRQSGGRVALESAPGQGTTVRLQLPRALTEVEKEVAPAVDEPSPA
GERLALVLEDEEDVRQTLCEQLHQLGWLTLETASGEEALQLLEASPDIALLISDLMLPGALSGADVIHTARRRFPALPVL
LISGQDLRPAQNPALPEVEWLRKPFTRAQLAQALSAAYARI

Sequences:

>Translated_761_residues
MTARRYPFFTSARGRLLSFNLLMVVVTLLVSGVAVFGFHHASQLQEQVQRQTLNDMRGSMDLARDTANVATAAVRLSQVV
GALEYKSEAERLLATQQALKHSLAQLAAAPLAQQEQARVANIIRRSNALQQSVAEMLERGQRRHLQRNALLSSLYQNQSN
LRHLADLNDRGGDKAIDPRRLAEMDRLIVAAIHTVTPRSIVLQLDQLRGALPTRSADPALAFVLPDVTRELATLAPLSAQ
LEESDLTISWYMYHIKALVALLNEDINQYVTRVAEASEQRAAQSHRELRSISMFILLSALLALAITGCAGWYIYRNLGSN
LTAISRAMSRLAQGEPNVSVPALQRRDELGELARAFNVFARNMASLEHTTRLLKEKTNQMEIDRIKRQELEEALLHSQKM
KAVGQLTGGLAHDFNNLLAVIIGSLELVEPDARDAPRLSRALKAAERGALLTQRLLAFSRKQALHPQAVAMAPLLENLSE
LMRHSLPATLSLEIEAQSPAWPAWIDVGQLENALINLVMNARDAMAGRDGVIKIRTWNQRVTRSSGQRQDMVALEVIDHG
SGMSQAVKARVFEPFFTTKATGSGSGLGLSMVYGFVRQSGGRVALESAPGQGTTVRLQLPRALTEVEKEVAPAVDEPSPA
GERLALVLEDEEDVRQTLCEQLHQLGWLTLETASGEEALQLLEASPDIALLISDLMLPGALSGADVIHTARRRFPALPVL
LISGQDLRPAQNPALPEVEWLRKPFTRAQLAQALSAAYARI
>Mature_760_residues
TARRYPFFTSARGRLLSFNLLMVVVTLLVSGVAVFGFHHASQLQEQVQRQTLNDMRGSMDLARDTANVATAAVRLSQVVG
ALEYKSEAERLLATQQALKHSLAQLAAAPLAQQEQARVANIIRRSNALQQSVAEMLERGQRRHLQRNALLSSLYQNQSNL
RHLADLNDRGGDKAIDPRRLAEMDRLIVAAIHTVTPRSIVLQLDQLRGALPTRSADPALAFVLPDVTRELATLAPLSAQL
EESDLTISWYMYHIKALVALLNEDINQYVTRVAEASEQRAAQSHRELRSISMFILLSALLALAITGCAGWYIYRNLGSNL
TAISRAMSRLAQGEPNVSVPALQRRDELGELARAFNVFARNMASLEHTTRLLKEKTNQMEIDRIKRQELEEALLHSQKMK
AVGQLTGGLAHDFNNLLAVIIGSLELVEPDARDAPRLSRALKAAERGALLTQRLLAFSRKQALHPQAVAMAPLLENLSEL
MRHSLPATLSLEIEAQSPAWPAWIDVGQLENALINLVMNARDAMAGRDGVIKIRTWNQRVTRSSGQRQDMVALEVIDHGS
GMSQAVKARVFEPFFTTKATGSGSGLGLSMVYGFVRQSGGRVALESAPGQGTTVRLQLPRALTEVEKEVAPAVDEPSPAG
ERLALVLEDEEDVRQTLCEQLHQLGWLTLETASGEEALQLLEASPDIALLISDLMLPGALSGADVIHTARRRFPALPVLL
ISGQDLRPAQNPALPEVEWLRKPFTRAQLAQALSAAYARI

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=30.1652892561983, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=29.6296296296296, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI1788713, Length=341, Percent_Identity=25.8064516129032, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI87081816, Length=467, Percent_Identity=25.4817987152034, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790300, Length=245, Percent_Identity=28.1632653061224, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83628; Mature: 83497

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50885 HAMP ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARRYPFFTSARGRLLSFNLLMVVVTLLVSGVAVFGFHHASQLQEQVQRQTLNDMRGSM
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLARDTANVATAAVRLSQVVGALEYKSEAERLLATQQALKHSLAQLAAAPLAQQEQARVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
NIIRRSNALQQSVAEMLERGQRRHLQRNALLSSLYQNQSNLRHLADLNDRGGDKAIDPRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCHHH
LAEMDRLIVAAIHTVTPRSIVLQLDQLRGALPTRSADPALAFVLPDVTRELATLAPLSAQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHCCHHHH
LEESDLTISWYMYHIKALVALLNEDINQYVTRVAEASEQRAAQSHRELRSISMFILLSAL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALAITGCAGWYIYRNLGSNLTAISRAMSRLAQGEPNVSVPALQRRDELGELARAFNVFA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RNMASLEHTTRLLKEKTNQMEIDRIKRQELEEALLHSQKMKAVGQLTGGLAHDFNNLLAV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIGSLELVEPDARDAPRLSRALKAAERGALLTQRLLAFSRKQALHPQAVAMAPLLENLSE
HHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LMRHSLPATLSLEIEAQSPAWPAWIDVGQLENALINLVMNARDAMAGRDGVIKIRTWNQR
HHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHH
VTRSSGQRQDMVALEVIDHGSGMSQAVKARVFEPFFTTKATGSGSGLGLSMVYGFVRQSG
HHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHHHHHCCC
GRVALESAPGQGTTVRLQLPRALTEVEKEVAPAVDEPSPAGERLALVLEDEEDVRQTLCE
CEEEEECCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHH
QLHQLGWLTLETASGEEALQLLEASPDIALLISDLMLPGALSGADVIHTARRRFPALPVL
HHHHCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEE
LISGQDLRPAQNPALPEVEWLRKPFTRAQLAQALSAAYARI
EECCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TARRYPFFTSARGRLLSFNLLMVVVTLLVSGVAVFGFHHASQLQEQVQRQTLNDMRGSM
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLARDTANVATAAVRLSQVVGALEYKSEAERLLATQQALKHSLAQLAAAPLAQQEQARVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
NIIRRSNALQQSVAEMLERGQRRHLQRNALLSSLYQNQSNLRHLADLNDRGGDKAIDPRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCHHH
LAEMDRLIVAAIHTVTPRSIVLQLDQLRGALPTRSADPALAFVLPDVTRELATLAPLSAQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHCCHHHH
LEESDLTISWYMYHIKALVALLNEDINQYVTRVAEASEQRAAQSHRELRSISMFILLSAL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALAITGCAGWYIYRNLGSNLTAISRAMSRLAQGEPNVSVPALQRRDELGELARAFNVFA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RNMASLEHTTRLLKEKTNQMEIDRIKRQELEEALLHSQKMKAVGQLTGGLAHDFNNLLAV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIGSLELVEPDARDAPRLSRALKAAERGALLTQRLLAFSRKQALHPQAVAMAPLLENLSE
HHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LMRHSLPATLSLEIEAQSPAWPAWIDVGQLENALINLVMNARDAMAGRDGVIKIRTWNQR
HHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHH
VTRSSGQRQDMVALEVIDHGSGMSQAVKARVFEPFFTTKATGSGSGLGLSMVYGFVRQSG
HHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHHHHHCCC
GRVALESAPGQGTTVRLQLPRALTEVEKEVAPAVDEPSPAGERLALVLEDEEDVRQTLCE
CEEEEECCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHHH
QLHQLGWLTLETASGEEALQLLEASPDIALLISDLMLPGALSGADVIHTARRRFPALPVL
HHHHCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEE
LISGQDLRPAQNPALPEVEWLRKPFTRAQLAQALSAAYARI
EECCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA