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The map label for this gene is cbl [H]

Identifier: 238028379

GI number: 238028379

Start: 3221081

End: 3222022

Strand: Direct

Name: cbl [H]

Synonym: bglu_1g28400

Alternate gene names: 238028379

Gene position: 3221081-3222022 (Clockwise)

Preceding gene: 238028372

Following gene: 238028380

Centisome position: 82.45

GC content: 64.12

Gene sequence:

>942_bases
ATGAACCTGCACCAATTTCGCTTCGTGCGCGAGGCCGTCCGCCAGAATTTCAACCTCACCGAGGCCGCGAAGGCGCTGTT
TACGTCGCAGCCGGGCGTGTCGAAGGCGATCATCGAGCTCGAGGACGAACTGGGCGTGGAAATCTTCAGGCGCCACGGCA
AGCGCGTGCGCTCGCTGACCGAACCGGGCCGGATCATCCTCGCCTCGGTCGAACGCATTTTGCAGGAAGTGGAAAGCTTA
AAAAGGGTCGGGAAAGATTACGCGGCGCAGGACCAGGGCAACCTGACGATCGCGGCCACGCATACCCAGGCGCGCTACTC
GCTGCCGGGGGCGATCGCCGAATTCAAGAAGCGGTTTCCGAAGGTGCATCTGTCGATCCTGCAAGGCAGCCCGACCCAGG
TGGCCGAGATGGTGATCCACGATCAGGCCGATCTCGCGATCGCGACCGAGGCGATCGCCGACTACAAGGAGTTGGTGTCG
CTGCCTTGCTTCCAGTGGCATCACGCCGCCGTGGTGCCGGCCGACCATCCGCTGCTGGAGCGGCGCCCGCCCTCGCTCGA
CGACCTGGCGCAATATCCGCTGATCACCTACGACGACGCGTTTGCGGGCCGCAAGAAGATCAATCACGCGTTCGCGCTGC
GCGGGCTGTCGCCCGACATCGTGCTGGAGGCGATCGACGCGGACGTGATCAAGACCTACGTGGAACTGGGGCTCGGGGTC
GGCATCCTGGCCGACATCGCGTTCAACCCGGAGCGCGACCGCAACCTGCGCGCGATTTCGGTCGGGCACCTGTTCGGCAG
CAACGTGACGCGCGTGGCGCTGAAACAAGGCGCGTACCTGCGCGGCTATGTATATACGCTCGTCGAATTGCTGTCGCCGA
CGCTGAACCGCAAGCTGATCGAGCAGGCGCTGCAGGGCGAGGCAGAATCCTACGAGCTGTGA

Upstream 100 bases:

>100_bases
AAACAGATATCCATATTTGAAAAACCAGGAAGGATCGTAATAAACTCGCCTTATATTTCAAACGACTAAAAAATTCTGTC
CATATGCGAAAGGGTTATAT

Downstream 100 bases:

>100_bases
GGGCGCAAGCGCTTTTCCCATGCGCGATGGCAAGGCGTGCACGGACACGGCCTGGCCGCCGGCCGCCGCGGCGCACGGGC
GGCTTGCCCGGCGCGGCGTT

Product: transcriptional regulator CysB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MNLHQFRFVREAVRQNFNLTEAAKALFTSQPGVSKAIIELEDELGVEIFRRHGKRVRSLTEPGRIILASVERILQEVESL
KRVGKDYAAQDQGNLTIAATHTQARYSLPGAIAEFKKRFPKVHLSILQGSPTQVAEMVIHDQADLAIATEAIADYKELVS
LPCFQWHHAAVVPADHPLLERRPPSLDDLAQYPLITYDDAFAGRKKINHAFALRGLSPDIVLEAIDADVIKTYVELGLGV
GILADIAFNPERDRNLRAISVGHLFGSNVTRVALKQGAYLRGYVYTLVELLSPTLNRKLIEQALQGEAESYEL

Sequences:

>Translated_313_residues
MNLHQFRFVREAVRQNFNLTEAAKALFTSQPGVSKAIIELEDELGVEIFRRHGKRVRSLTEPGRIILASVERILQEVESL
KRVGKDYAAQDQGNLTIAATHTQARYSLPGAIAEFKKRFPKVHLSILQGSPTQVAEMVIHDQADLAIATEAIADYKELVS
LPCFQWHHAAVVPADHPLLERRPPSLDDLAQYPLITYDDAFAGRKKINHAFALRGLSPDIVLEAIDADVIKTYVELGLGV
GILADIAFNPERDRNLRAISVGHLFGSNVTRVALKQGAYLRGYVYTLVELLSPTLNRKLIEQALQGEAESYEL
>Mature_313_residues
MNLHQFRFVREAVRQNFNLTEAAKALFTSQPGVSKAIIELEDELGVEIFRRHGKRVRSLTEPGRIILASVERILQEVESL
KRVGKDYAAQDQGNLTIAATHTQARYSLPGAIAEFKKRFPKVHLSILQGSPTQVAEMVIHDQADLAIATEAIADYKELVS
LPCFQWHHAAVVPADHPLLERRPPSLDDLAQYPLITYDDAFAGRKKINHAFALRGLSPDIVLEAIDADVIKTYVELGLGV
GILADIAFNPERDRNLRAISVGHLFGSNVTRVALKQGAYLRGYVYTLVELLSPTLNRKLIEQALQGEAESYEL

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=309, Percent_Identity=45.9546925566343, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI1787530, Length=304, Percent_Identity=44.078947368421, Blast_Score=286, Evalue=9e-79,
Organism=Escherichia coli, GI157672245, Length=213, Percent_Identity=34.2723004694836, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI145693105, Length=245, Percent_Identity=26.530612244898, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790399, Length=255, Percent_Identity=25.0980392156863, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788481, Length=247, Percent_Identity=27.1255060728745, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788887, Length=249, Percent_Identity=28.1124497991968, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789204, Length=242, Percent_Identity=25.6198347107438, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787601, Length=149, Percent_Identity=28.1879194630872, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87082132, Length=147, Percent_Identity=25.8503401360544, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34852; Mature: 34852

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHQFRFVREAVRQNFNLTEAAKALFTSQPGVSKAIIELEDELGVEIFRRHGKRVRSLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EPGRIILASVERILQEVESLKRVGKDYAAQDQGNLTIAATHTQARYSLPGAIAEFKKRFP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHCCCHHHHHHHHHCC
KVHLSILQGSPTQVAEMVIHDQADLAIATEAIADYKELVSLPCFQWHHAAVVPADHPLLE
HHEEHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHH
RRPPSLDDLAQYPLITYDDAFAGRKKINHAFALRGLSPDIVLEAIDADVIKTYVELGLGV
CCCCCHHHHHHCCEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCH
GILADIAFNPERDRNLRAISVGHLFGSNVTRVALKQGAYLRGYVYTLVELLSPTLNRKLI
HHHHHHCCCCCCCCCCEEEEECHHHCCCHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHH
EQALQGEAESYEL
HHHHCCCCCCCCC
>Mature Secondary Structure
MNLHQFRFVREAVRQNFNLTEAAKALFTSQPGVSKAIIELEDELGVEIFRRHGKRVRSLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EPGRIILASVERILQEVESLKRVGKDYAAQDQGNLTIAATHTQARYSLPGAIAEFKKRFP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHCCCHHHHHHHHHCC
KVHLSILQGSPTQVAEMVIHDQADLAIATEAIADYKELVSLPCFQWHHAAVVPADHPLLE
HHEEHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHH
RRPPSLDDLAQYPLITYDDAFAGRKKINHAFALRGLSPDIVLEAIDADVIKTYVELGLGV
CCCCCHHHHHHCCEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCH
GILADIAFNPERDRNLRAISVGHLFGSNVTRVALKQGAYLRGYVYTLVELLSPTLNRKLI
HHHHHHCCCCCCCCCCEEEEECHHHCCCHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHH
EQALQGEAESYEL
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]