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The map label for this gene is ansA [H]

Identifier: 238027011

GI number: 238027011

Start: 1530400

End: 1531434

Strand: Direct

Name: ansA [H]

Synonym: bglu_1g13890

Alternate gene names: 238027011

Gene position: 1530400-1531434 (Clockwise)

Preceding gene: 238027008

Following gene: 238027015

Centisome position: 39.18

GC content: 71.59

Gene sequence:

>1035_bases
ATGACCTATTCGACCCCCCACCCCAACTCCGCCGGCACCGCGCCGGCGCTGCCGCGCATCGCGGTCCTCGCCACCGGCGG
CACCATCGCCGGCGCCGCTGCCGACGCCACCAATACCGCCGGCTATCAGGCCGGCGCGCTCGGCATCGGCTCGTTGCTCG
ACGCGGTGCCGGCACTCGCGCGCGTCGCGCAAATCGTCGGCGAGCAGATCGCCAGCATCGACAGCAAGGATCTCGAACCG
GCGCTCTGGAGCACGCTCGCCGCGCGCATCGACGCGCTCGCGGCCGACGACGCGATCGACGGCATCGTGATCACGCACGG
CACCGACACGCTGGAAGAAACCGCCTGCCTGCTGCACCTGAGCGTCAAGACCAGCAAGCCGGTGGTGTTGACGGCCGCCA
TGCGGCCGGCCACGGCGCTTTCCCCGGACGGCCCGCTGAATCTGCTCAACGCGGTGACCGTGGCCGCGCATCGCGCCGCG
CACGGGCAGGGCGTGCTGGTCGCGTTCAACAACAAGATCCACAGCGCGCGCGACGTGGTAAAGACCAGCACCTATGCCGT
CGACGCCTTCCAGTCGCCGGAGCTGGGCGTGCTGGGCTGGGTACAGGACGGCCGCGTCGAGTTCGCGCGCGGCGTCACGC
GCCCGCACACGGCGGCCACGCGCTTCTCGATCGGCACCGACTGGCCGGCCGTGGAGATCGTCGCGAGCTACGCCGGCGTG
TCGCGGGTCGGCGTCGATGCGCTGGTGGCGGCCGGCGTGAAGGGCATCGTGGTGGCCGGCACCGGCAACGGCTCGATCCA
CGTGCGGCTGCAGGAGGCGCTCGTCGAAGCCGCGCGCCGCGGCGTGGCGGTGGTGCGCGCCTCGCGGGTCGGCTCGGGGC
ACGTGATGCGCAATGGCGCGGCCAACGACGACGCGCTGGGCTTTATCAGCGCCGGCTCGCTCAATCCGTTCAAGGCACGC
GTGCTGCTGATGCTCGCGCTCGCGGCCGGCGTGAGCGATCCGGCCGAATTGCAGACCGTGTTCGATACCTACTGA

Upstream 100 bases:

>100_bases
AACGCGAGTCGGGCGAGCGCGCTGCTGCTGGCGCCGGATGCCGCCGCGCCGAGCGCGAAGGGTTGCCGAAGCACGGTGGA
CAGCGATTACAATCGCGGCC

Downstream 100 bases:

>100_bases
CGCGCCGCGCCCGCCGCCGCGCGGCTGGCGAGAAGGCATGAAAAAAAACGGACCCGCATGGTCCGTTTTTTTCATGGCCA
TCGCCCCGGGGCGGCGGGCG

Product: L-asparaginase, type II

Products: NA

Alternate protein names: L-ASNase; L-asparagine amidohydrolase [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTYSTPHPNSAGTAPALPRIAVLATGGTIAGAAADATNTAGYQAGALGIGSLLDAVPALARVAQIVGEQIASIDSKDLEP
ALWSTLAARIDALAADDAIDGIVITHGTDTLEETACLLHLSVKTSKPVVLTAAMRPATALSPDGPLNLLNAVTVAAHRAA
HGQGVLVAFNNKIHSARDVVKTSTYAVDAFQSPELGVLGWVQDGRVEFARGVTRPHTAATRFSIGTDWPAVEIVASYAGV
SRVGVDALVAAGVKGIVVAGTGNGSIHVRLQEALVEAARRGVAVVRASRVGSGHVMRNGAANDDALGFISAGSLNPFKAR
VLLMLALAAGVSDPAELQTVFDTY

Sequences:

>Translated_344_residues
MTYSTPHPNSAGTAPALPRIAVLATGGTIAGAAADATNTAGYQAGALGIGSLLDAVPALARVAQIVGEQIASIDSKDLEP
ALWSTLAARIDALAADDAIDGIVITHGTDTLEETACLLHLSVKTSKPVVLTAAMRPATALSPDGPLNLLNAVTVAAHRAA
HGQGVLVAFNNKIHSARDVVKTSTYAVDAFQSPELGVLGWVQDGRVEFARGVTRPHTAATRFSIGTDWPAVEIVASYAGV
SRVGVDALVAAGVKGIVVAGTGNGSIHVRLQEALVEAARRGVAVVRASRVGSGHVMRNGAANDDALGFISAGSLNPFKAR
VLLMLALAAGVSDPAELQTVFDTY
>Mature_343_residues
TYSTPHPNSAGTAPALPRIAVLATGGTIAGAAADATNTAGYQAGALGIGSLLDAVPALARVAQIVGEQIASIDSKDLEPA
LWSTLAARIDALAADDAIDGIVITHGTDTLEETACLLHLSVKTSKPVVLTAAMRPATALSPDGPLNLLNAVTVAAHRAAH
GQGVLVAFNNKIHSARDVVKTSTYAVDAFQSPELGVLGWVQDGRVEFARGVTRPHTAATRFSIGTDWPAVEIVASYAGVS
RVGVDALVAAGVKGIVVAGTGNGSIHVRLQEALVEAARRGVAVVRASRVGSGHVMRNGAANDDALGFISAGSLNPFKARV
LLMLALAAGVSDPAELQTVFDTY

Specific function: Unknown

COG id: COG0252

COG function: function code EJ; L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the asparaginase 1 family [H]

Homologues:

Organism=Homo sapiens, GI122937331, Length=241, Percent_Identity=29.8755186721992, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1789327, Length=336, Percent_Identity=45.2380952380952, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1788065, Length=295, Percent_Identity=30.5084745762712, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI193207374, Length=325, Percent_Identity=28.6153846153846, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17558280, Length=325, Percent_Identity=28.6153846153846, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI193207372, Length=325, Percent_Identity=28.6153846153846, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17558278, Length=325, Percent_Identity=28.6153846153846, Blast_Score=81, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6323189, Length=326, Percent_Identity=38.3435582822086, Blast_Score=185, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6323187, Length=326, Percent_Identity=38.3435582822086, Blast_Score=185, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6323186, Length=326, Percent_Identity=38.3435582822086, Blast_Score=185, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6323184, Length=326, Percent_Identity=38.3435582822086, Blast_Score=185, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6320527, Length=338, Percent_Identity=34.9112426035503, Blast_Score=181, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24639609, Length=241, Percent_Identity=27.3858921161826, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24645530, Length=240, Percent_Identity=30, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004550
- InterPro:   IPR006034
- InterPro:   IPR020827 [H]

Pfam domain/function: PF00710 Asparaginase [H]

EC number: =3.5.1.1 [H]

Molecular weight: Translated: 35010; Mature: 34879

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00144 ASN_GLN_ASE_1 ; PS00917 ASN_GLN_ASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYSTPHPNSAGTAPALPRIAVLATGGTIAGAAADATNTAGYQAGALGIGSLLDAVPALA
CCCCCCCCCCCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RVAQIVGEQIASIDSKDLEPALWSTLAARIDALAADDAIDGIVITHGTDTLEETACLLHL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHCEEEEEE
SVKTSKPVVLTAAMRPATALSPDGPLNLLNAVTVAAHRAAHGQGVLVAFNNKIHSARDVV
EECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
KTSTYAVDAFQSPELGVLGWVQDGRVEFARGVTRPHTAATRFSIGTDWPAVEIVASYAGV
HHHHEEEECCCCCCCCEEEEEECCCCHHHHCCCCCCCHHEEEECCCCCHHHHHHHHHHCH
SRVGVDALVAAGVKGIVVAGTGNGSIHVRLQEALVEAARRGVAVVRASRVGSGHVMRNGA
HHHHHHHHHHCCCCEEEEEECCCCEEEEEEHHHHHHHHHCCEEEEEECCCCCCCEEECCC
ANDDALGFISAGSLNPFKARVLLMLALAAGVSDPAELQTVFDTY
CCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure 
TYSTPHPNSAGTAPALPRIAVLATGGTIAGAAADATNTAGYQAGALGIGSLLDAVPALA
CCCCCCCCCCCCCCCCCCEEEEEECCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RVAQIVGEQIASIDSKDLEPALWSTLAARIDALAADDAIDGIVITHGTDTLEETACLLHL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHCEEEEEE
SVKTSKPVVLTAAMRPATALSPDGPLNLLNAVTVAAHRAAHGQGVLVAFNNKIHSARDVV
EECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
KTSTYAVDAFQSPELGVLGWVQDGRVEFARGVTRPHTAATRFSIGTDWPAVEIVASYAGV
HHHHEEEECCCCCCCCEEEEEECCCCHHHHCCCCCCCHHEEEECCCCCHHHHHHHHHHCH
SRVGVDALVAAGVKGIVVAGTGNGSIHVRLQEALVEAARRGVAVVRASRVGSGHVMRNGA
HHHHHHHHHHCCCCEEEEEECCCCEEEEEEHHHHHHHHHCCEEEEEECCCCCCCEEECCC
ANDDALGFISAGSLNPFKARVLLMLALAAGVSDPAELQTVFDTY
CCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8898907; 14500908 [H]