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The map label for this gene is tmk [H]

Identifier: 238027001

GI number: 238027001

Start: 1521136

End: 1521756

Strand: Direct

Name: tmk [H]

Synonym: bglu_1g13790

Alternate gene names: 238027001

Gene position: 1521136-1521756 (Clockwise)

Preceding gene: 238027000

Following gene: 238027002

Centisome position: 38.94

GC content: 71.82

Gene sequence:

>621_bases
ATGGCGCGTGGAAAATTCATCACGTTCGAAGGGATCGACGGCGCGGGCAAGACCACGCACCTCGCCTGGTTCTGCGAACA
CCTGCGCGCGAAGATCGCGCCCGCCGGGCGGCAAGTCGTGCAGACCCGCGAGCCGGGCGGCACGGTGCTCGGCGAGGCGC
TGCGCGCGCTGCTGCTGGAGCAGCCGATGGACCTGGAGACCGAGGCGCTGCTGATGTTCGCGGGCCGCCGCGAGCATCTC
GCGCGCGTGATCGAGCCGGCCCTCACGCGCGGCGACTGGGTGGTCTCGGACCGCTTTACCGACGCGACGTTCGCTTACCA
GGGCGGCGGCCGCGGGCTGCCGCGCGACAAGCTCGAGGCGCTCGAGCGCTGGGTGCAGGGCGGCTTCCAGCCGGACCTGA
CGGTCCTGTTCGACGTGCCGCCCGAGGTGGCGAGCGAGCGGCGCGGCGCGGTGCGCGCACCCGACAAGTTCGAGAGCGAG
AGCGAGGCGTTTTTCCTGCGCACGCGCGCCGAATACCTGCGCCGCGCCGAGGAAGCCCCGCACCGCTTCCTGATCGTCGA
CGCGACGCAGTCGATCCCGCAGATCCAGCGGCAGCTCGAAGGCGTGCTGGCCGCGCTCTGA

Upstream 100 bases:

>100_bases
CGGCACTCTACTTCGTGGCCAAGGGCGACGGAACCAGCGTGTTCTCGGACACGCTGGGGGATCACAACAAGGCCGTGGAC
AAATACATTCGAGGTCAATG

Downstream 100 bases:

>100_bases
TGCCGGCCGCCGGCAACCCTTAAGACCCGCTCATCCGACCAGAGGCCGACAAACCGATGATCTATCCGTGGCAAACCGAC
GACTGGGACCGGCTGCAGGC

Product: thymidylate kinase

Products: NA

Alternate protein names: dTMP kinase [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MARGKFITFEGIDGAGKTTHLAWFCEHLRAKIAPAGRQVVQTREPGGTVLGEALRALLLEQPMDLETEALLMFAGRREHL
ARVIEPALTRGDWVVSDRFTDATFAYQGGGRGLPRDKLEALERWVQGGFQPDLTVLFDVPPEVASERRGAVRAPDKFESE
SEAFFLRTRAEYLRRAEEAPHRFLIVDATQSIPQIQRQLEGVLAAL

Sequences:

>Translated_206_residues
MARGKFITFEGIDGAGKTTHLAWFCEHLRAKIAPAGRQVVQTREPGGTVLGEALRALLLEQPMDLETEALLMFAGRREHL
ARVIEPALTRGDWVVSDRFTDATFAYQGGGRGLPRDKLEALERWVQGGFQPDLTVLFDVPPEVASERRGAVRAPDKFESE
SEAFFLRTRAEYLRRAEEAPHRFLIVDATQSIPQIQRQLEGVLAAL
>Mature_205_residues
ARGKFITFEGIDGAGKTTHLAWFCEHLRAKIAPAGRQVVQTREPGGTVLGEALRALLLEQPMDLETEALLMFAGRREHLA
RVIEPALTRGDWVVSDRFTDATFAYQGGGRGLPRDKLEALERWVQGGFQPDLTVLFDVPPEVASERRGAVRAPDKFESES
EAFFLRTRAEYLRRAEEAPHRFLIVDATQSIPQIQRQLEGVLAAL

Specific function: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis [H]

COG id: COG0125

COG function: function code F; Thymidylate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidylate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787340, Length=199, Percent_Identity=42.2110552763819, Blast_Score=133, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018094 [H]

Pfam domain/function: PF02223 Thymidylate_kin [H]

EC number: =2.7.4.9 [H]

Molecular weight: Translated: 23011; Mature: 22879

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARGKFITFEGIDGAGKTTHLAWFCEHLRAKIAPAGRQVVQTREPGGTVLGEALRALLLE
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHC
QPMDLETEALLMFAGRREHLARVIEPALTRGDWVVSDRFTDATFAYQGGGRGLPRDKLEA
CCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCEEEECCCCCCCCHHHHHH
LERWVQGGFQPDLTVLFDVPPEVASERRGAVRAPDKFESESEAFFLRTRAEYLRRAEEAP
HHHHHHCCCCCCEEEEEECCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
HRFLIVDATQSIPQIQRQLEGVLAAL
CEEEEEECHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARGKFITFEGIDGAGKTTHLAWFCEHLRAKIAPAGRQVVQTREPGGTVLGEALRALLLE
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHHHHHHHC
QPMDLETEALLMFAGRREHLARVIEPALTRGDWVVSDRFTDATFAYQGGGRGLPRDKLEA
CCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCEEEECCCCCCCCHHHHHH
LERWVQGGFQPDLTVLFDVPPEVASERRGAVRAPDKFESESEAFFLRTRAEYLRRAEEAP
HHHHHHCCCCCCEEEEEECCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
HRFLIVDATQSIPQIQRQLEGVLAAL
CEEEEEECHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA