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The map label for this gene is btuE [C]

Identifier: 238026887

GI number: 238026887

Start: 1373954

End: 1374433

Strand: Direct

Name: btuE [C]

Synonym: bglu_1g12550

Alternate gene names: 238026887

Gene position: 1373954-1374433 (Clockwise)

Preceding gene: 238026885

Following gene: 238026894

Centisome position: 35.17

GC content: 66.25

Gene sequence:

>480_bases
ATGTCGACACTCTATTCATTCAGCGCCAACGCGCTCGGCGGCGGCGAGGTCTCGCTCGATGCCTATCGCGGCAAGGTGCT
GCTGATCGTCAACACCGCGAGCGAATGCGGGTTCACGCCGCAGTACGCGGGCCTGCAGCAGCTGCACGAGCGCTTCGGCG
CGCGCGGGCTGGCCGTGCTCGGCTTCCCGTGCAACCAGTTCGGCGGCCAGGAGCCCGGCGACGCCGCGCAGATCGGCGCG
TTCTGCGAGCAGCGCTTCGGCGTCACGTTCCCGCTGTTCGAGAAGATCGACGTGAAGGGCGAGCATGCGCATCCGCTGTT
CCGCTACCTGACCGACGAGGCGCCGGGCCTGCTCGGCACCAAGATGATCAAGTGGAATTTCACGAAGTTCCTGGCGGACC
GCAGCGGCAACGTCGTCAAGCGCTACGCGCCGCAGACCAAGCCCGACGAGATCGCCGAGGACATCGAAAAGCTGCTGTGA

Upstream 100 bases:

>100_bases
GACGGTTTCGCATAGACTGCGTGACGGGCGGCGGCCGGTCGCCGCGTTTCGAAACGCCGCCGCAGTTCCCATTCGCCCAT
ATCCGTCAGGAGGCAAACCG

Downstream 100 bases:

>100_bases
GCTGCCCGGCGGCGCGGTGCCGGGGCCGGGGCCGGGGCGGCTCAGAGGATCGGCGCGAACAGCCGCGCGACGTGTATCAG
CATGCGCCGCCAGGCGCCCG

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSTLYSFSANALGGGEVSLDAYRGKVLLIVNTASECGFTPQYAGLQQLHERFGARGLAVLGFPCNQFGGQEPGDAAQIGA
FCEQRFGVTFPLFEKIDVKGEHAHPLFRYLTDEAPGLLGTKMIKWNFTKFLADRSGNVVKRYAPQTKPDEIAEDIEKLL

Sequences:

>Translated_159_residues
MSTLYSFSANALGGGEVSLDAYRGKVLLIVNTASECGFTPQYAGLQQLHERFGARGLAVLGFPCNQFGGQEPGDAAQIGA
FCEQRFGVTFPLFEKIDVKGEHAHPLFRYLTDEAPGLLGTKMIKWNFTKFLADRSGNVVKRYAPQTKPDEIAEDIEKLL
>Mature_158_residues
STLYSFSANALGGGEVSLDAYRGKVLLIVNTASECGFTPQYAGLQQLHERFGARGLAVLGFPCNQFGGQEPGDAAQIGAF
CEQRFGVTFPLFEKIDVKGEHAHPLFRYLTDEAPGLLGTKMIKWNFTKFLADRSGNVVKRYAPQTKPDEIAEDIEKLL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI192455698, Length=160, Percent_Identity=40.625, Blast_Score=134, Evalue=3e-32,
Organism=Homo sapiens, GI75709200, Length=156, Percent_Identity=45.5128205128205, Blast_Score=133, Evalue=6e-32,
Organism=Homo sapiens, GI90903240, Length=156, Percent_Identity=45.5128205128205, Blast_Score=133, Evalue=7e-32,
Organism=Homo sapiens, GI15618997, Length=157, Percent_Identity=43.9490445859873, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI41406084, Length=182, Percent_Identity=42.8571428571429, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=45.0381679389313, Blast_Score=107, Evalue=3e-24,
Organism=Homo sapiens, GI4557629, Length=173, Percent_Identity=39.8843930635838, Blast_Score=106, Evalue=7e-24,
Organism=Homo sapiens, GI6006001, Length=173, Percent_Identity=36.9942196531792, Blast_Score=97, Evalue=5e-21,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=35.9116022099448, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI33186887, Length=177, Percent_Identity=35.5932203389831, Blast_Score=90, Evalue=8e-19,
Organism=Homo sapiens, GI41406082, Length=70, Percent_Identity=58.5714285714286, Blast_Score=73, Evalue=9e-14,
Organism=Escherichia coli, GI1788003, Length=156, Percent_Identity=42.9487179487179, Blast_Score=134, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17506887, Length=160, Percent_Identity=46.25, Blast_Score=152, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17535473, Length=160, Percent_Identity=44.375, Blast_Score=144, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI193210707, Length=162, Percent_Identity=45.0617283950617, Blast_Score=130, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71993584, Length=158, Percent_Identity=38.6075949367089, Blast_Score=125, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17550320, Length=180, Percent_Identity=32.2222222222222, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI193209493, Length=180, Percent_Identity=30.5555555555556, Blast_Score=96, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI193210709, Length=72, Percent_Identity=50, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=35.7894736842105, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=36.8421052631579, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=158, Percent_Identity=48.1012658227848, Blast_Score=172, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6322228, Length=159, Percent_Identity=47.7987421383648, Blast_Score=171, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6322826, Length=159, Percent_Identity=45.2830188679245, Blast_Score=160, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24656772, Length=160, Percent_Identity=46.25, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=46.25, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24656767, Length=160, Percent_Identity=46.25, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=45.2830188679245, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17435; Mature: 17304

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLYSFSANALGGGEVSLDAYRGKVLLIVNTASECGFTPQYAGLQQLHERFGARGLAVL
CCCCCCCCCCCCCCCCEEEEEECCEEEEEEECCHHCCCCCCHHHHHHHHHHHCCCCEEEE
GFPCNQFGGQEPGDAAQIGAFCEQRFGVTFPLFEKIDVKGEHAHPLFRYLTDEAPGLLGT
ECCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCHHHHHHHCCCCCCCHH
KMIKWNFTKFLADRSGNVVKRYAPQTKPDEIAEDIEKLL
EEHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
STLYSFSANALGGGEVSLDAYRGKVLLIVNTASECGFTPQYAGLQQLHERFGARGLAVL
CCCCCCCCCCCCCCCEEEEEECCEEEEEEECCHHCCCCCCHHHHHHHHHHHCCCCEEEE
GFPCNQFGGQEPGDAAQIGAFCEQRFGVTFPLFEKIDVKGEHAHPLFRYLTDEAPGLLGT
ECCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCHHHHHHHCCCCCCCHH
KMIKWNFTKFLADRSGNVVKRYAPQTKPDEIAEDIEKLL
EEHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]