Click here to switch to the map view.

The map label for this gene is atoC [H]

Identifier: 238026806

GI number: 238026806

Start: 1277474

End: 1278838

Strand: Direct

Name: atoC [H]

Synonym: bglu_1g11650

Alternate gene names: 238026806

Gene position: 1277474-1278838 (Clockwise)

Preceding gene: 238026804

Following gene: 238026807

Centisome position: 32.7

GC content: 68.94

Gene sequence:

>1365_bases
ATGCCCTACATTCTGGTCGTCGAAGACGACGCCGACACCCGTGACATGCTTTCCGCGCTCGCGCAGACGCAGCAACTGAC
CTGCGATACCGCGGCGACGCTGGCGCAGGCGCGCGAGCTGATCGCGCAGCACACGCCGGATCTGGTGCTGTGCGACCTGG
TGCTGCCCGACGGCAGCGGCATGGATCTGTTCGACGAGCTGCCCAAGGGCGTCCATTGCGAAATGGTGCTGACCACCGGC
CACGCGAGCCTGGAGACGGCGATCGACGCCTTGCGGCGCGGCGCGACCGACTATCTCGTCAAGCCGCTCAACATGCAGCG
CCTGAACGCGATCTTCGCGCGCGTGCCGCGCACCAGCGTGCTGCACGAGGAGATCGCCTTGCTGCGCAGCGAGCTCAAGC
AGCTGGGCCGCTTCGGCCGCATGCTCGGCAACTCGCCGCCGATGCAGGCGATGTACGACGCCATCAGCCGGGTCGCGAGC
ACCGAGGCGTCGGTGCTGCTCAAGGGCGAGTCGGGCACCGGCAAGGAGCTGGCGGCGCAGACCATCCACGACCTGAGCCT
GCGCCGCAAGGGGCCGTTCCTCGCGATCAACTGCGGGGCGATCGCGGCGAACCTGGTCGAAAGCGAGATGTTCGGCCACG
ACTGCGGCAGCTTCACGGGCGCGGACCGCCAGCACAAGGGCTTTTTCGAGCGCGCCGACGGCGGCACGCTGTTCCTCGAC
GAAATCACCGAGATGCCGATGGAGTCGCAGGTCAAGCTGCTGCGCGTGCTCGAGACGGGACGCCTCACGCGCCTCGGCTC
GGCGCGCGAGCTGGACGTGGACGTGCGGATCGTGGCGGCCACCAACCGCGATCCCGAGGCCGCGATGGCCGAGGGCAGGC
TGCGTCCCGACCTCTATCACCGCATCAACGTGTTCCCGATCACGCTGCCGTCGCTGCGCGAGCGCGGCGACGACATTCCG
ATGCTGGCGGTGGCGTTCCTCAATCGGCTCAACGAGGAGAGCGGCCGCAAGATGCGCTTCGCGCCCGCCGCGCTGGCGGC
GCTGGCCGGCTACGAATGGCCGGGCAACGTGCGCGAGCTGCGCAACTTCGTGCAGCGCGCGAGCATCTTCAACGACGGCG
AGGTGATCGACACGCTGCCGCCGCCGATCATGGCCGAGGTGTCGGGCGACGCGGTGGGCGCTGACGACACGGTGTCGGTG
CCGTTCGGCACCACGCTCGAGGAAGTCGACCGGCGCGTGATCCTCGGCACGCTGGCGCAGTGCGGCGGGGTGAAGACGCA
TGCCGCCGAGGTGCTCGACATCAGCCTGAAGACGATCTACAACCGCCTCGCGCAGCTCGAAGGCGGGGACAAGACCGCGT
CGTGA

Upstream 100 bases:

>100_bases
ACTGCAGCCCGACCCGCTATTCGACCCTTACCCGATACAGCACGTCGCCGACAGGCCGGCCTTGGCGGCCGGCCGGCGCG
TGCTCCGCGATGGAGCGTCA

Downstream 100 bases:

>100_bases
GCGCCACGGCGGCGATGGCGCCGGCGCGTGACGTCCCGGCATGCCGGGCAAGGTGGGCCGCCGCGGCGGCCGGCGCGGGC
GTGCGGCCGGCATGGCGGCG

Product: Sigma-54 dependent DNA-binding response regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MPYILVVEDDADTRDMLSALAQTQQLTCDTAATLAQARELIAQHTPDLVLCDLVLPDGSGMDLFDELPKGVHCEMVLTTG
HASLETAIDALRRGATDYLVKPLNMQRLNAIFARVPRTSVLHEEIALLRSELKQLGRFGRMLGNSPPMQAMYDAISRVAS
TEASVLLKGESGTGKELAAQTIHDLSLRRKGPFLAINCGAIAANLVESEMFGHDCGSFTGADRQHKGFFERADGGTLFLD
EITEMPMESQVKLLRVLETGRLTRLGSARELDVDVRIVAATNRDPEAAMAEGRLRPDLYHRINVFPITLPSLRERGDDIP
MLAVAFLNRLNEESGRKMRFAPAALAALAGYEWPGNVRELRNFVQRASIFNDGEVIDTLPPPIMAEVSGDAVGADDTVSV
PFGTTLEEVDRRVILGTLAQCGGVKTHAAEVLDISLKTIYNRLAQLEGGDKTAS

Sequences:

>Translated_454_residues
MPYILVVEDDADTRDMLSALAQTQQLTCDTAATLAQARELIAQHTPDLVLCDLVLPDGSGMDLFDELPKGVHCEMVLTTG
HASLETAIDALRRGATDYLVKPLNMQRLNAIFARVPRTSVLHEEIALLRSELKQLGRFGRMLGNSPPMQAMYDAISRVAS
TEASVLLKGESGTGKELAAQTIHDLSLRRKGPFLAINCGAIAANLVESEMFGHDCGSFTGADRQHKGFFERADGGTLFLD
EITEMPMESQVKLLRVLETGRLTRLGSARELDVDVRIVAATNRDPEAAMAEGRLRPDLYHRINVFPITLPSLRERGDDIP
MLAVAFLNRLNEESGRKMRFAPAALAALAGYEWPGNVRELRNFVQRASIFNDGEVIDTLPPPIMAEVSGDAVGADDTVSV
PFGTTLEEVDRRVILGTLAQCGGVKTHAAEVLDISLKTIYNRLAQLEGGDKTAS
>Mature_453_residues
PYILVVEDDADTRDMLSALAQTQQLTCDTAATLAQARELIAQHTPDLVLCDLVLPDGSGMDLFDELPKGVHCEMVLTTGH
ASLETAIDALRRGATDYLVKPLNMQRLNAIFARVPRTSVLHEEIALLRSELKQLGRFGRMLGNSPPMQAMYDAISRVAST
EASVLLKGESGTGKELAAQTIHDLSLRRKGPFLAINCGAIAANLVESEMFGHDCGSFTGADRQHKGFFERADGGTLFLDE
ITEMPMESQVKLLRVLETGRLTRLGSARELDVDVRIVAATNRDPEAAMAEGRLRPDLYHRINVFPITLPSLRERGDDIPM
LAVAFLNRLNEESGRKMRFAPAALAALAGYEWPGNVRELRNFVQRASIFNDGEVIDTLPPPIMAEVSGDAVGADDTVSVP
FGTTLEEVDRRVILGTLAQCGGVKTHAAEVLDISLKTIYNRLAQLEGGDKTAS

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=451, Percent_Identity=39.689578713969, Blast_Score=326, Evalue=2e-90,
Organism=Escherichia coli, GI1790437, Length=451, Percent_Identity=40.3547671840355, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI1790299, Length=466, Percent_Identity=36.2660944206009, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI1788905, Length=453, Percent_Identity=35.5408388520971, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1789087, Length=322, Percent_Identity=42.5465838509317, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI87082117, Length=260, Percent_Identity=46.1538461538462, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI1789233, Length=323, Percent_Identity=40.5572755417957, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI1786524, Length=341, Percent_Identity=39.5894428152493, Blast_Score=215, Evalue=6e-57,
Organism=Escherichia coli, GI87081872, Length=267, Percent_Identity=43.0711610486891, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI87082152, Length=232, Percent_Identity=46.551724137931, Blast_Score=208, Evalue=6e-55,
Organism=Escherichia coli, GI1787583, Length=267, Percent_Identity=38.2022471910112, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1789828, Length=289, Percent_Identity=33.5640138408304, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI87081858, Length=319, Percent_Identity=30.7210031347962, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786838, Length=127, Percent_Identity=33.8582677165354, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49434; Mature: 49303

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYILVVEDDADTRDMLSALAQTQQLTCDTAATLAQARELIAQHTPDLVLCDLVLPDGSG
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
MDLFDELPKGVHCEMVLTTGHASLETAIDALRRGATDYLVKPLNMQRLNAIFARVPRTSV
CCHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHCCCHHH
LHEEIALLRSELKQLGRFGRMLGNSPPMQAMYDAISRVASTEASVLLKGESGTGKELAAQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHH
TIHDLSLRRKGPFLAINCGAIAANLVESEMFGHDCGSFTGADRQHKGFFERADGGTLFLD
HHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCEECCCCEEEHH
EITEMPMESQVKLLRVLETGRLTRLGSARELDVDVRIVAATNRDPEAAMAEGRLRPDLYH
HHHCCCHHHHHHHHHHHHCCCCEECCCCCEECEEEEEEEECCCCCHHHHHCCCCCCCHHH
RINVFPITLPSLRERGDDIPMLAVAFLNRLNEESGRKMRFAPAALAALAGYEWPGNVREL
EEEEEEEECHHHHHCCCCCHHHHHHHHHHHCHHCCCEEEEHHHHHHHHHCCCCCCCHHHH
RNFVQRASIFNDGEVIDTLPPPIMAEVSGDAVGADDTVSVPFGTTLEEVDRRVILGTLAQ
HHHHHHHHCCCCCCEECCCCCCCEEECCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHH
CGGVKTHAAEVLDISLKTIYNRLAQLEGGDKTAS
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PYILVVEDDADTRDMLSALAQTQQLTCDTAATLAQARELIAQHTPDLVLCDLVLPDGSG
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
MDLFDELPKGVHCEMVLTTGHASLETAIDALRRGATDYLVKPLNMQRLNAIFARVPRTSV
CCHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHCCCHHH
LHEEIALLRSELKQLGRFGRMLGNSPPMQAMYDAISRVASTEASVLLKGESGTGKELAAQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHH
TIHDLSLRRKGPFLAINCGAIAANLVESEMFGHDCGSFTGADRQHKGFFERADGGTLFLD
HHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCEECCCCEEEHH
EITEMPMESQVKLLRVLETGRLTRLGSARELDVDVRIVAATNRDPEAAMAEGRLRPDLYH
HHHCCCHHHHHHHHHHHHCCCCEECCCCCEECEEEEEEEECCCCCHHHHHCCCCCCCHHH
RINVFPITLPSLRERGDDIPMLAVAFLNRLNEESGRKMRFAPAALAALAGYEWPGNVREL
EEEEEEEECHHHHHCCCCCHHHHHHHHHHHCHHCCCEEEEHHHHHHHHHCCCCCCCHHHH
RNFVQRASIFNDGEVIDTLPPPIMAEVSGDAVGADDTVSVPFGTTLEEVDRRVILGTLAQ
HHHHHHHHCCCCCCEECCCCCCCEEECCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHH
CGGVKTHAAEVLDISLKTIYNRLAQLEGGDKTAS
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]