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The map label for this gene is bvgS [H]

Identifier: 238026807

GI number: 238026807

Start: 1278993

End: 1281314

Strand: Direct

Name: bvgS [H]

Synonym: bglu_1g11660

Alternate gene names: 238026807

Gene position: 1278993-1281314 (Clockwise)

Preceding gene: 238026806

Following gene: 238026808

Centisome position: 32.74

GC content: 73.9

Gene sequence:

>2322_bases
ATGACGGGTGCCGCGCTGGTCGCGATGGCGACGGTGCTGCAGTCGCTGCTGGTCCACTACGGCGGCCCGAACATGCCGCT
GCTGCTCTACTACCCCTTCATCGCGGGCGTGGCGTGGACGATCTCGTTCGGCGCCGGCCTCGTCGCCTCGCTCGTGAGCG
CGCTGCTGATCTGGCTGCTGTTCGTCAGCGACCCGCGCGCCTATCCGCTGGTGCCCGCGATGCAGGCCATGCAGATCGGC
CTGTTCCTGCTGGTGTCGGGCGTGGTCTGCGCCGTGGTGGCCGCGTTTCACCATTCGCGGCTGACCAACGACGCGCTGCG
CCGCCGCGAGGCCGCCGCGCGCCAGCAATACGAGTCGGTGCTCGCGTCGCTGACGCAGGGCGTGATCGTTACCGATTCGG
CCGGCCGCATCACCTACCTGAACCCGGCCGCGGCCGCGCTCGCCGATCTCGACGCCCGCGTCGCGCACGGCCGCGCGCTG
ACCGACGCGCTGCACGGCAACGACGGCCACGGCGCCGGCACGCGCTCGACCACCGTGCTCGAACGCGTGCTTCGCGGTGA
GCCCGGCGCCTCCGACCTGCTGTGGCTGCGGCCCGCCGGGCAGGGCGCGCGCATTCCGGTGGCCGCCGTCGCCTCGCCGC
TGTGCGACCCGGACGGCGTGCGCAGCGGCGCGGTGCTGGTGCTGCGCGACGTCAGCGCCGATCACGAGCGCGCCACCGCG
AACCAGATGCTGCGGCGGCTCGTCGACGCTTCGCCCGACGCCATCATCGGGGTGGGCGCCGATCGCCTGATCACGAGCTG
GAACCCGGCCGCGCAGCGCATGTTCGGCTATGCCGAGGCGCAGGCGCTCGGCCGCGACGCCGGCATGCTGGTCGCGCCGC
GCTGGCAGCGCCGCCATCCGCTTGCCGCGGCGGTGCGCGACGTGCATGACGCCGTGAGCGGCGTGGACCTGCTCTGCGTG
CGCGAGAACGGCGAGCGGTTCCGCGCGACGCTGGCCGCCTCGCCGGTGTTCGACGACGAGCAGGTCTGCGTGGCGCTGTC
GCTGACGCTGCGCGACGCGCGCCTGCAGCGCCGCCGCGAGCGCGACAATCATCATCGGCTGCGCGGCGCGCGCGACGCGC
GGCGCCAGGCCGACACCTCGAACCGCCTGAAGGACGAGCTGCTCGCGATCGTCTCGCACGAGCTGCGCACGCCGCTCAAC
GTGATCTACGGCTGGGTGGAGGTGATGCGCAACCCGGTGGCCGAGGCGCTGCAGCGTCAGGCAATCGACGCGATCGACCG
CAGCGCCCGTTCGCTGTCGCGGATGGTGGCCGACCTGCTCGACGCCTCGTCGCTCGCCACCGGCAAGCTGCGGCTCGACC
CGATGCCGGTCGATCTGGTGCGGGTGGTGGCCGACGTCACGGGCGCGCTCGGCACCACGGCCGCCAACGAGGGCATCACG
CTCGAGACGCACTGCGAGCTCGACACCTGCATCGTGTCGGGCGACGCCGAGCGGCTCAGGCAGATGCTCTCGAACCTGCT
GTCGAACGCCTTCAAGTTCACGCCGCGCGGCGGCCGCGTGACGGTGGCGCTCAGCCGCGAGAACGCCCGCGCGCTGCTGA
GCGTGACCGACACGGGGCAGGGCGTGGCGCCCGAATTCCTGCCGCACGTATTCGAGGCGTTCCGGCGCGCCGAGGGCTCG
CCCGCCTCACCGCGCCGCGGCCTCGGGCTGGGCCTGTCGATCGTGCGCCACATCGCCGAGCTGCACGGCGGCAGCGCGCG
CGTGACGAGCGACGGCACCGGCCACGGCACCACCTTCGAGGTCGCGCTGCCGGCCGGCTGGCAGCCGGCCGGCACGCTGA
CCTGGGCCGCCCAGACGACGAGCGCGCCGGCCACGCGCGAGCGGCTGCACCTCGGCGGGCAGCGCATCCTGCTGGTCGAC
GACGACGCCACCTCGCGCACCAGCCTCGCCACCGCGCTCGCCACGCTCGGCGCCGAGATCGTGGTGGCCGAGTCGGGGCG
CGACGCGCTCGCCAGGATCGAGGCCGCGCGGCCTACCGTCGTGCTGTCCGATCTCGCGATGCCGGACGGCGACGGGTTCT
GGCTGCTCGACGCGCTGCATGGCGGCAACTACACGACCGCGCCGGTGCTGGCCGTGACTGCCCACGCCGGGCAGGCCGAC
GAGCGGCGCGTGCTGGCCGCCGGCTTCGACGCTTATCTGTGCAAGCCGGTCGACATCCAGCTGCTCGCACGCGAGATCCT
GCGCACTACGCAGGCGCGCGGCGAGGTGCCGACGCACGCGTTGCCGCCGCCGCAGGCGCTCGACTCGCGGCTGCCCGACT
GA

Upstream 100 bases:

>100_bases
GGGCCGCCGCGGCGGCCGGCGCGGGCGTGCGGCCGGCATGGCGGCGCGGACGGGAATCGAACGGATGACCCAAATGCAAT
CAGGCTGGATTCGAAATGGC

Downstream 100 bases:

>100_bases
GCCGCCGGCTCGCCCGCCCGATCCGGGGCGGGCGCCTCGTCCCCCGGCTTGCGCATGCCGAGCGCGGCCTCGCCAGCGCG
TTCCGTTCCCGCTTCGGGCC

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 773; Mature: 772

Protein sequence:

>773_residues
MTGAALVAMATVLQSLLVHYGGPNMPLLLYYPFIAGVAWTISFGAGLVASLVSALLIWLLFVSDPRAYPLVPAMQAMQIG
LFLLVSGVVCAVVAAFHHSRLTNDALRRREAAARQQYESVLASLTQGVIVTDSAGRITYLNPAAAALADLDARVAHGRAL
TDALHGNDGHGAGTRSTTVLERVLRGEPGASDLLWLRPAGQGARIPVAAVASPLCDPDGVRSGAVLVLRDVSADHERATA
NQMLRRLVDASPDAIIGVGADRLITSWNPAAQRMFGYAEAQALGRDAGMLVAPRWQRRHPLAAAVRDVHDAVSGVDLLCV
RENGERFRATLAASPVFDDEQVCVALSLTLRDARLQRRRERDNHHRLRGARDARRQADTSNRLKDELLAIVSHELRTPLN
VIYGWVEVMRNPVAEALQRQAIDAIDRSARSLSRMVADLLDASSLATGKLRLDPMPVDLVRVVADVTGALGTTAANEGIT
LETHCELDTCIVSGDAERLRQMLSNLLSNAFKFTPRGGRVTVALSRENARALLSVTDTGQGVAPEFLPHVFEAFRRAEGS
PASPRRGLGLGLSIVRHIAELHGGSARVTSDGTGHGTTFEVALPAGWQPAGTLTWAAQTTSAPATRERLHLGGQRILLVD
DDATSRTSLATALATLGAEIVVAESGRDALARIEAARPTVVLSDLAMPDGDGFWLLDALHGGNYTTAPVLAVTAHAGQAD
ERRVLAAGFDAYLCKPVDIQLLAREILRTTQARGEVPTHALPPPQALDSRLPD

Sequences:

>Translated_773_residues
MTGAALVAMATVLQSLLVHYGGPNMPLLLYYPFIAGVAWTISFGAGLVASLVSALLIWLLFVSDPRAYPLVPAMQAMQIG
LFLLVSGVVCAVVAAFHHSRLTNDALRRREAAARQQYESVLASLTQGVIVTDSAGRITYLNPAAAALADLDARVAHGRAL
TDALHGNDGHGAGTRSTTVLERVLRGEPGASDLLWLRPAGQGARIPVAAVASPLCDPDGVRSGAVLVLRDVSADHERATA
NQMLRRLVDASPDAIIGVGADRLITSWNPAAQRMFGYAEAQALGRDAGMLVAPRWQRRHPLAAAVRDVHDAVSGVDLLCV
RENGERFRATLAASPVFDDEQVCVALSLTLRDARLQRRRERDNHHRLRGARDARRQADTSNRLKDELLAIVSHELRTPLN
VIYGWVEVMRNPVAEALQRQAIDAIDRSARSLSRMVADLLDASSLATGKLRLDPMPVDLVRVVADVTGALGTTAANEGIT
LETHCELDTCIVSGDAERLRQMLSNLLSNAFKFTPRGGRVTVALSRENARALLSVTDTGQGVAPEFLPHVFEAFRRAEGS
PASPRRGLGLGLSIVRHIAELHGGSARVTSDGTGHGTTFEVALPAGWQPAGTLTWAAQTTSAPATRERLHLGGQRILLVD
DDATSRTSLATALATLGAEIVVAESGRDALARIEAARPTVVLSDLAMPDGDGFWLLDALHGGNYTTAPVLAVTAHAGQAD
ERRVLAAGFDAYLCKPVDIQLLAREILRTTQARGEVPTHALPPPQALDSRLPD
>Mature_772_residues
TGAALVAMATVLQSLLVHYGGPNMPLLLYYPFIAGVAWTISFGAGLVASLVSALLIWLLFVSDPRAYPLVPAMQAMQIGL
FLLVSGVVCAVVAAFHHSRLTNDALRRREAAARQQYESVLASLTQGVIVTDSAGRITYLNPAAAALADLDARVAHGRALT
DALHGNDGHGAGTRSTTVLERVLRGEPGASDLLWLRPAGQGARIPVAAVASPLCDPDGVRSGAVLVLRDVSADHERATAN
QMLRRLVDASPDAIIGVGADRLITSWNPAAQRMFGYAEAQALGRDAGMLVAPRWQRRHPLAAAVRDVHDAVSGVDLLCVR
ENGERFRATLAASPVFDDEQVCVALSLTLRDARLQRRRERDNHHRLRGARDARRQADTSNRLKDELLAIVSHELRTPLNV
IYGWVEVMRNPVAEALQRQAIDAIDRSARSLSRMVADLLDASSLATGKLRLDPMPVDLVRVVADVTGALGTTAANEGITL
ETHCELDTCIVSGDAERLRQMLSNLLSNAFKFTPRGGRVTVALSRENARALLSVTDTGQGVAPEFLPHVFEAFRRAEGSP
ASPRRGLGLGLSIVRHIAELHGGSARVTSDGTGHGTTFEVALPAGWQPAGTLTWAAQTTSAPATRERLHLGGQRILLVDD
DATSRTSLATALATLGAEIVVAESGRDALARIEAARPTVVLSDLAMPDGDGFWLLDALHGGNYTTAPVLAVTAHAGQADE
RRVLAAGFDAYLCKPVDIQLLAREILRTTQARGEVPTHALPPPQALDSRLPD

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=508, Percent_Identity=28.3464566929134, Blast_Score=146, Evalue=5e-36,
Organism=Escherichia coli, GI1788713, Length=394, Percent_Identity=30.4568527918782, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI87081816, Length=380, Percent_Identity=29.4736842105263, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1789149, Length=296, Percent_Identity=30.0675675675676, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788393, Length=227, Percent_Identity=30.8370044052863, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786600, Length=244, Percent_Identity=32.7868852459016, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786783, Length=218, Percent_Identity=32.1100917431193, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI145693157, Length=289, Percent_Identity=27.3356401384083, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1788549, Length=390, Percent_Identity=22.5641025641026, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=28.7449392712551, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=30.7359307359307, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=216, Percent_Identity=30.5555555555556, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=26.431718061674, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1788279, Length=215, Percent_Identity=26.9767441860465, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=239, Percent_Identity=30.9623430962343, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1789808, Length=224, Percent_Identity=29.0178571428571, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1790551, Length=211, Percent_Identity=28.9099526066351, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=36.4406779661017, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82462; Mature: 82331

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGAALVAMATVLQSLLVHYGGPNMPLLLYYPFIAGVAWTISFGAGLVASLVSALLIWLL
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVSDPRAYPLVPAMQAMQIGLFLLVSGVVCAVVAAFHHSRLTNDALRRREAAARQQYESV
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LASLTQGVIVTDSAGRITYLNPAAAALADLDARVAHGRALTDALHGNDGHGAGTRSTTVL
HHHHHCCEEEECCCCCEEEECHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCHHHHHH
ERVLRGEPGASDLLWLRPAGQGARIPVAAVASPLCDPDGVRSGAVLVLRDVSADHERATA
HHHHCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHH
NQMLRRLVDASPDAIIGVGADRLITSWNPAAQRMFGYAEAQALGRDAGMLVAPRWQRRHP
HHHHHHHHCCCCCEEEECCHHHHEECCCHHHHHHHHHHHHHHHCCCCCEEECCCHHHCCC
LAAAVRDVHDAVSGVDLLCVRENGERFRATLAASPVFDDEQVCVALSLTLRDARLQRRRE
HHHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHH
RDNHHRLRGARDARRQADTSNRLKDELLAIVSHELRTPLNVIYGWVEVMRNPVAEALQRQ
CCHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AIDAIDRSARSLSRMVADLLDASSLATGKLRLDPMPVDLVRVVADVTGALGTTAANEGIT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEE
LETHCELDTCIVSGDAERLRQMLSNLLSNAFKFTPRGGRVTVALSRENARALLSVTDTGQ
EEEECCEEEEEECCCHHHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCEEEEEEECCCC
GVAPEFLPHVFEAFRRAEGSPASPRRGLGLGLSIVRHIAELHGGSARVTSDGTGHGTTFE
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCEEE
VALPAGWQPAGTLTWAAQTTSAPATRERLHLGGQRILLVDDDATSRTSLATALATLGAEI
EEECCCCCCCCCEEEEECCCCCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCEE
VVAESGRDALARIEAARPTVVLSDLAMPDGDGFWLLDALHGGNYTTAPVLAVTAHAGQAD
EEECCCCHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCC
ERRVLAAGFDAYLCKPVDIQLLAREILRTTQARGEVPTHALPPPQALDSRLPD
CCEEEEECCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCC
>Mature Secondary Structure 
TGAALVAMATVLQSLLVHYGGPNMPLLLYYPFIAGVAWTISFGAGLVASLVSALLIWLL
CCHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVSDPRAYPLVPAMQAMQIGLFLLVSGVVCAVVAAFHHSRLTNDALRRREAAARQQYESV
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LASLTQGVIVTDSAGRITYLNPAAAALADLDARVAHGRALTDALHGNDGHGAGTRSTTVL
HHHHHCCEEEECCCCCEEEECHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCHHHHHH
ERVLRGEPGASDLLWLRPAGQGARIPVAAVASPLCDPDGVRSGAVLVLRDVSADHERATA
HHHHCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHH
NQMLRRLVDASPDAIIGVGADRLITSWNPAAQRMFGYAEAQALGRDAGMLVAPRWQRRHP
HHHHHHHHCCCCCEEEECCHHHHEECCCHHHHHHHHHHHHHHHCCCCCEEECCCHHHCCC
LAAAVRDVHDAVSGVDLLCVRENGERFRATLAASPVFDDEQVCVALSLTLRDARLQRRRE
HHHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHH
RDNHHRLRGARDARRQADTSNRLKDELLAIVSHELRTPLNVIYGWVEVMRNPVAEALQRQ
CCHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AIDAIDRSARSLSRMVADLLDASSLATGKLRLDPMPVDLVRVVADVTGALGTTAANEGIT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEE
LETHCELDTCIVSGDAERLRQMLSNLLSNAFKFTPRGGRVTVALSRENARALLSVTDTGQ
EEEECCEEEEEECCCHHHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCEEEEEEECCCC
GVAPEFLPHVFEAFRRAEGSPASPRRGLGLGLSIVRHIAELHGGSARVTSDGTGHGTTFE
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCEEE
VALPAGWQPAGTLTWAAQTTSAPATRERLHLGGQRILLVDDDATSRTSLATALATLGAEI
EEECCCCCCCCCEEEEECCCCCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCEE
VVAESGRDALARIEAARPTVVLSDLAMPDGDGFWLLDALHGGNYTTAPVLAVTAHAGQAD
EEECCCCHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCC
ERRVLAAGFDAYLCKPVDIQLLAREILRTTQARGEVPTHALPPPQALDSRLPD
CCEEEEECCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]