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The map label for this gene is lrp [H]

Identifier: 238024815

GI number: 238024815

Start: 1852860

End: 1853327

Strand: Direct

Name: lrp [H]

Synonym: bglu_2g14530

Alternate gene names: 238024815

Gene position: 1852860-1853327 (Clockwise)

Preceding gene: 238024813

Following gene: 238024818

Centisome position: 65.53

GC content: 60.68

Gene sequence:

>468_bases
ATGCCGGAAATTGATAGTGTAGACGCCGAGATCCTGAATCGGCTGCAAAAGGATGGGCGCTTGTCCAATGCCAAGCTCGC
CGCCCAGCTTTCGATGAGCGAAACGCCGTGCTGGCGCCGCCTCAAGCGCCTGGAGGACTGCGGGATCATCGAAGGCTATC
AGGCCGTGTTGAATCGCCGAAAACTCGGGCTAGGGGTCATGGCCTTCGTTCAGCTGGTCTGCACGCAGCACGACGAGAAG
GTCACGCAGGCGTTCCAACTGGCCGTGCAAAGCAGCCCGAACGTCCTGTCCTGCCACAACACGACCGGCGAAGCCGACTT
CCTGCTGATGGTCGTTGCCCGCGACCTCGACGACTACAGCCGCTTCGTCGAAAAAGTCCTGAGACACCTGCCCGGCGTCG
CCAGCATCCGTTCGAACCTGTCGCTGCGAGAGCTGAAATCCTCGAATCTGCTGCCGGTCTCGAGCTAA

Upstream 100 bases:

>100_bases
GACCGGCAGAAAAAAATTGTCTTGCCGAATCCTCTCGCATCAGGCCAATTTTTGATATTGTCTTTCAGATATCGTCGATA
TTTAGAAAGAGACCCTCTCC

Downstream 100 bases:

>100_bases
TTCCTCACGACGCGACACAACCCGGCGCGCTCCCGGGCGTCGGCACGGCGCGGTGGGCGCCGTTGCAGCCCGGGACGGCA
AGAATCTACAGATCGAGCAC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MPEIDSVDAEILNRLQKDGRLSNAKLAAQLSMSETPCWRRLKRLEDCGIIEGYQAVLNRRKLGLGVMAFVQLVCTQHDEK
VTQAFQLAVQSSPNVLSCHNTTGEADFLLMVVARDLDDYSRFVEKVLRHLPGVASIRSNLSLRELKSSNLLPVSS

Sequences:

>Translated_155_residues
MPEIDSVDAEILNRLQKDGRLSNAKLAAQLSMSETPCWRRLKRLEDCGIIEGYQAVLNRRKLGLGVMAFVQLVCTQHDEK
VTQAFQLAVQSSPNVLSCHNTTGEADFLLMVVARDLDDYSRFVEKVLRHLPGVASIRSNLSLRELKSSNLLPVSS
>Mature_154_residues
PEIDSVDAEILNRLQKDGRLSNAKLAAQLSMSETPCWRRLKRLEDCGIIEGYQAVLNRRKLGLGVMAFVQLVCTQHDEKV
TQAFQLAVQSSPNVLSCHNTTGEADFLLMVVARDLDDYSRFVEKVLRHLPGVASIRSNLSLRELKSSNLLPVSS

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=153, Percent_Identity=36.6013071895425, Blast_Score=114, Evalue=2e-27,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=35.3333333333333, Blast_Score=109, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17296; Mature: 17165

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEIDSVDAEILNRLQKDGRLSNAKLAAQLSMSETPCWRRLKRLEDCGIIEGYQAVLNRR
CCCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
KLGLGVMAFVQLVCTQHDEKVTQAFQLAVQSSPNVLSCHNTTGEADFLLMVVARDLDDYS
HCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCHHHHH
RFVEKVLRHLPGVASIRSNLSLRELKSSNLLPVSS
HHHHHHHHHCCCHHHHHHCCHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PEIDSVDAEILNRLQKDGRLSNAKLAAQLSMSETPCWRRLKRLEDCGIIEGYQAVLNRR
CCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHH
KLGLGVMAFVQLVCTQHDEKVTQAFQLAVQSSPNVLSCHNTTGEADFLLMVVARDLDDYS
HCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCHHHHH
RFVEKVLRHLPGVASIRSNLSLRELKSSNLLPVSS
HHHHHHHHHCCCHHHHHHCCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]