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The map label for this gene is yisQ [H]

Identifier: 229918220

GI number: 229918220

Start: 2462310

End: 2463668

Strand: Reverse

Name: yisQ [H]

Synonym: EAT1b_2500

Alternate gene names: 229918220

Gene position: 2463668-2462310 (Counterclockwise)

Preceding gene: 229918221

Following gene: 229918218

Centisome position: 82.13

GC content: 54.23

Gene sequence:

>1359_bases
ATGCAGACGAAACAAACGGAACAGCTCACCCTGTTCAAACTGTCGTGGCCGATTTTCATCGAACTTGCCCTCCATATGGG
AACCGGGATCATCGCCACATTGATGCTCGCTCACTACTCAGACGCTGCCGCTTCGGCCGTCGGGGTTGCCAACCAAATCT
TAAACGTGTTCTTGATCGTCTTTAGTGTGACGTCTGTCGGGGCGACTATTTTGATCGGTCAGGCCATCGGGGCTGGGCGC
ATGAAGAAGAGTCGCGACTTCGCCCGCTCCGCCGTCAGTTTGAACATGTGGCTCGGTGCGATCATGGTCATCGTCATCTT
CTTGTTCGGCGAAACGTTCTTACGCCTGTTCGGTCTATCGGACGAACTGTTTGCACACGGGTTGTTGTTCCTGCAAATCG
TCGGCTTGTCGTTATTCACCGAAGCGCTCATCATGGCGCTCAGTTCGATCCTCCGGAGTCACGGGATGACGAAACACGCC
ATGCTCGCGACGCTTCTGATTGATATCATCACCGCCGTCGGTGCCATTTTTGCCGTTACCGGCTGGTTCGGCCTTCCGGT
CACAGGCGTTGCCGGAGTCGCTTGGGCCATCGTGATCGCACGATTCGCCGCTATGGTACTGTTGTTCTGGCTCGTCAAAC
GGAAGCTCATGATCCGCTTCCCGTTAAAAGAAGTGATTCGTCCGAAGAAAGACGACATCCAGTCACTCCTTCAAATCGGT
GTTCCTTCTGCCGGGGAGAACTTGTCGTATCAAGCTTCACAGATTATCATCACTGGTTTTATCGCGACGATGGGTGAAGC
TTCTCTTGCTGCTCGCGTGTACGTAATGAACTTATCCATGCTTGCCTTCTTGTTCACCGTCGCCGTCGCGCAAGGGACCC
AGCTTTTGATCGCACGGGACATTGGAGGGAAACGTTTTAAAGAAGCCTATCATCGTGCCGTCAAGACCTTGAAGATTGCC
ATGTTCGCTTCGTTCGTCGCCTCTCTCGGTTTAGCGGTGTTCAGCGAATCGCTACTCGGTCTCTTCACGTCAAACCCTGA
CATCATCGCGGTCGGTGTGCCGATCTTATGGGCGACGCTCATTTTAGAGCCGGGTCGCGCCATGAACATCGTCTTGATGG
GGTCGTTGAAGTCTGTCGGGGACGTCCGCTTCCCGGTCATGATTGGGATCGCCTCGATGTGGGGTGTCGCCGTGGCGTTC
AGCTACTTGTTCGGTCTTCAAATGGGGCTCGGCATCCTTGGGATTTGGCTCGCCTTCTCCCTCGATGAGTGGTTCCGCGG
ATTCTTCGCGTTCCGTCGTTGGAAATACGGGACGTGGCAACAAAAAGGCTTCCAGTTCGAAGCAAAATCAACCACGTAA

Upstream 100 bases:

>100_bases
CCTTTCTTTTTCATTTCATAAGGAGTAAGATGACCTTTGACATTTTTATAAAACAAATAGTTAACAGAAAGAATTATAGA
GAAAAGGGAGAATACACTAC

Downstream 100 bases:

>100_bases
AAAAGCGGCCGCGGCCGCTTTTTTCATTTCATCAAGAATGCCTGCATCGCTTGGCGGTGCACGTCCGTGTCCCCACACTT
CCGTTGCCATTCGATTTCTT

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MQTKQTEQLTLFKLSWPIFIELALHMGTGIIATLMLAHYSDAAASAVGVANQILNVFLIVFSVTSVGATILIGQAIGAGR
MKKSRDFARSAVSLNMWLGAIMVIVIFLFGETFLRLFGLSDELFAHGLLFLQIVGLSLFTEALIMALSSILRSHGMTKHA
MLATLLIDIITAVGAIFAVTGWFGLPVTGVAGVAWAIVIARFAAMVLLFWLVKRKLMIRFPLKEVIRPKKDDIQSLLQIG
VPSAGENLSYQASQIIITGFIATMGEASLAARVYVMNLSMLAFLFTVAVAQGTQLLIARDIGGKRFKEAYHRAVKTLKIA
MFASFVASLGLAVFSESLLGLFTSNPDIIAVGVPILWATLILEPGRAMNIVLMGSLKSVGDVRFPVMIGIASMWGVAVAF
SYLFGLQMGLGILGIWLAFSLDEWFRGFFAFRRWKYGTWQQKGFQFEAKSTT

Sequences:

>Translated_452_residues
MQTKQTEQLTLFKLSWPIFIELALHMGTGIIATLMLAHYSDAAASAVGVANQILNVFLIVFSVTSVGATILIGQAIGAGR
MKKSRDFARSAVSLNMWLGAIMVIVIFLFGETFLRLFGLSDELFAHGLLFLQIVGLSLFTEALIMALSSILRSHGMTKHA
MLATLLIDIITAVGAIFAVTGWFGLPVTGVAGVAWAIVIARFAAMVLLFWLVKRKLMIRFPLKEVIRPKKDDIQSLLQIG
VPSAGENLSYQASQIIITGFIATMGEASLAARVYVMNLSMLAFLFTVAVAQGTQLLIARDIGGKRFKEAYHRAVKTLKIA
MFASFVASLGLAVFSESLLGLFTSNPDIIAVGVPILWATLILEPGRAMNIVLMGSLKSVGDVRFPVMIGIASMWGVAVAF
SYLFGLQMGLGILGIWLAFSLDEWFRGFFAFRRWKYGTWQQKGFQFEAKSTT
>Mature_452_residues
MQTKQTEQLTLFKLSWPIFIELALHMGTGIIATLMLAHYSDAAASAVGVANQILNVFLIVFSVTSVGATILIGQAIGAGR
MKKSRDFARSAVSLNMWLGAIMVIVIFLFGETFLRLFGLSDELFAHGLLFLQIVGLSLFTEALIMALSSILRSHGMTKHA
MLATLLIDIITAVGAIFAVTGWFGLPVTGVAGVAWAIVIARFAAMVLLFWLVKRKLMIRFPLKEVIRPKKDDIQSLLQIG
VPSAGENLSYQASQIIITGFIATMGEASLAARVYVMNLSMLAFLFTVAVAQGTQLLIARDIGGKRFKEAYHRAVKTLKIA
MFASFVASLGLAVFSESLLGLFTSNPDIIAVGVPILWATLILEPGRAMNIVLMGSLKSVGDVRFPVMIGIASMWGVAVAF
SYLFGLQMGLGILGIWLAFSLDEWFRGFFAFRRWKYGTWQQKGFQFEAKSTT

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=440, Percent_Identity=22.0454545454545, Blast_Score=121, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49302; Mature: 49302

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTKQTEQLTLFKLSWPIFIELALHMGTGIIATLMLAHYSDAAASAVGVANQILNVFLIV
CCCCCCCCEEEEEECCHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
FSVTSVGATILIGQAIGAGRMKKSRDFARSAVSLNMWLGAIMVIVIFLFGETFLRLFGLS
HHHHHHCHHHEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DELFAHGLLFLQIVGLSLFTEALIMALSSILRSHGMTKHAMLATLLIDIITAVGAIFAVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GWFGLPVTGVAGVAWAIVIARFAAMVLLFWLVKRKLMIRFPLKEVIRPKKDDIQSLLQIG
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHC
VPSAGENLSYQASQIIITGFIATMGEASLAARVYVMNLSMLAFLFTVAVAQGTQLLIARD
CCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
IGGKRFKEAYHRAVKTLKIAMFASFVASLGLAVFSESLLGLFTSNPDIIAVGVPILWATL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHH
ILEPGRAMNIVLMGSLKSVGDVRFPVMIGIASMWGVAVAFSYLFGLQMGLGILGIWLAFS
HHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDEWFRGFFAFRRWKYGTWQQKGFQFEAKSTT
HHHHHHHHHHHHHCCCCCCHHCCEEEECCCCC
>Mature Secondary Structure
MQTKQTEQLTLFKLSWPIFIELALHMGTGIIATLMLAHYSDAAASAVGVANQILNVFLIV
CCCCCCCCEEEEEECCHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
FSVTSVGATILIGQAIGAGRMKKSRDFARSAVSLNMWLGAIMVIVIFLFGETFLRLFGLS
HHHHHHCHHHEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DELFAHGLLFLQIVGLSLFTEALIMALSSILRSHGMTKHAMLATLLIDIITAVGAIFAVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GWFGLPVTGVAGVAWAIVIARFAAMVLLFWLVKRKLMIRFPLKEVIRPKKDDIQSLLQIG
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHC
VPSAGENLSYQASQIIITGFIATMGEASLAARVYVMNLSMLAFLFTVAVAQGTQLLIARD
CCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
IGGKRFKEAYHRAVKTLKIAMFASFVASLGLAVFSESLLGLFTSNPDIIAVGVPILWATL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHH
ILEPGRAMNIVLMGSLKSVGDVRFPVMIGIASMWGVAVAFSYLFGLQMGLGILGIWLAFS
HHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDEWFRGFFAFRRWKYGTWQQKGFQFEAKSTT
HHHHHHHHHHHHHCCCCCCHHCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]