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The map label for this gene is panC

Identifier: 227815613

GI number: 227815613

Start: 2765739

End: 2766587

Strand: Reverse

Name: panC

Synonym: BAMEG_3032

Alternate gene names: 227815613

Gene position: 2766587-2765739 (Counterclockwise)

Preceding gene: 227815614

Following gene: 227815612

Centisome position: 52.9

GC content: 36.98

Gene sequence:

>849_bases
ATGAAAATCGTAACGACAGTACAAGAGATGCAGCACATTACAAAAGAACTGCGTGCAAGTGGAAAAAGTATTGGTTTTGT
CCCAACGATGGGGTATTTACATGAAGGTCATGCGACTTTATTACGTAAGGCAAGAGAAGAAAATGAAATTGTAGTTTTAA
GCGTGTTTGTAAATCCACTACAGTTTGGACCGAATGAAGATTTAGATCGATATCCTCGTGATATTGATAGAGATGAAAAT
GTAGCAAAAGAAAACGGTGTAGATTATTTATTTTATCCGAGTGTAGAAGAAATGTATCCAGCAGAACAAACGACAACGGT
AGAAGTTGTGAAGCGTACCGATGTATTATGCGGTAAACAAAGACCAGGTCATTTCGCTGGTGTTGCGACTGTACTCATGA
AACTATTTAACATTACATTGCCAACACGCGCGTATTTCGGTATGAAAGATGCACAGCAAGTTGCTGTCATTGAAGGATTT
GTCGCTGATTTTAATATTCCGGTTATAATCGTACCGGTGGATATTGTAAGGGAAGAAGATGGATTAGCGAAAAGTTCTCG
TAACGTGTATTTATCACAAAAAGAGCGTAAAGAGGCTCCTCATTTATACCGCAGTCTATGTATGGCAAAAGAAAGAATTG
AGGCAGGAGAACGGAATGCAGAAATTATTACAACTCTTGTAAAAGAATATATTGAGACGTATACGAAAGGCACTGTAGAT
TATGCGGATTTATATGCCTACCCTTCACTACAAGTAGTGGATCAAATTGAAGGGCGAATCATTTTAGCAATTGCAGTTAA
ATTTGAAAATGTACGATTAATTGACAATATAACATTAACGGTTAAATAA

Upstream 100 bases:

>100_bases
AATATGTTGCTGAAGTAAAGACAAGGCAATTTCCTGAAGAAAAACATTCGTTCACAATGAAAGAGGAAGAATGCTTAGCG
TTATACGGAGGAAAACAATC

Downstream 100 bases:

>100_bases
GGGGGAGCATCTATGTTTCGCACAATGATGAGAGCGAAGTTACATCGCGCAACAGTAACAGAAGCAAATTTAAATTATGT
AGGTAGTATTACAATTGATG

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKIVTTVQEMQHITKELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPLQFGPNEDLDRYPRDIDRDEN
VAKENGVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGKQRPGHFAGVATVLMKLFNITLPTRAYFGMKDAQQVAVIEGF
VADFNIPVIIVPVDIVREEDGLAKSSRNVYLSQKERKEAPHLYRSLCMAKERIEAGERNAEIITTLVKEYIETYTKGTVD
YADLYAYPSLQVVDQIEGRIILAIAVKFENVRLIDNITLTVK

Sequences:

>Translated_282_residues
MKIVTTVQEMQHITKELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPLQFGPNEDLDRYPRDIDRDEN
VAKENGVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGKQRPGHFAGVATVLMKLFNITLPTRAYFGMKDAQQVAVIEGF
VADFNIPVIIVPVDIVREEDGLAKSSRNVYLSQKERKEAPHLYRSLCMAKERIEAGERNAEIITTLVKEYIETYTKGTVD
YADLYAYPSLQVVDQIEGRIILAIAVKFENVRLIDNITLTVK
>Mature_282_residues
MKIVTTVQEMQHITKELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPLQFGPNEDLDRYPRDIDRDEN
VAKENGVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGKQRPGHFAGVATVLMKLFNITLPTRAYFGMKDAQQVAVIEGF
VADFNIPVIIVPVDIVREEDGLAKSSRNVYLSQKERKEAPHLYRSLCMAKERIEAGERNAEIITTLVKEYIETYTKGTVD
YADLYAYPSLQVVDQIEGRIILAIAVKFENVRLIDNITLTVK

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family

Homologues:

Organism=Escherichia coli, GI1786325, Length=279, Percent_Identity=41.5770609318996, Blast_Score=205, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6322046, Length=310, Percent_Identity=39.0322580645161, Blast_Score=181, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PANC_BACAA (C3P5R0)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002866043.1
- ProteinModelPortal:   C3P5R0
- SMR:   C3P5R0
- EnsemblBacteria:   EBBACT00000127736
- GeneID:   7853564
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_1630
- GeneTree:   EBGT00050000001451
- ProtClustDB:   PRK00380
- GO:   GO:0005737
- HAMAP:   MF_00158
- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR21299:SF1
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00018

Pfam domain/function: PF02569 Pantoate_ligase

EC number: =6.3.2.1

Molecular weight: Translated: 31962; Mature: 31962

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: ACT_SITE 37-37 BINDING 61-61 BINDING 61-61 BINDING 153-153 BINDING 176-176

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVTTVQEMQHITKELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPL
CCHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHCCHHHHHHHHCCCCCEEEEEEEECHH
QFGPNEDLDRYPRDIDRDENVAKENGVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGKQ
CCCCCCCHHHCCCCCCCCCCHHHHCCCCEEECCCHHHHCCCCCCHHHHHHHHHHHHCCCC
RPGHFAGVATVLMKLFNITLPTRAYFGMKDAQQVAVIEGFVADFNIPVIIVPVDIVREED
CCCHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHEECCC
GLAKSSRNVYLSQKERKEAPHLYRSLCMAKERIEAGERNAEIITTLVKEYIETYTKGTVD
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
YADLYAYPSLQVVDQIEGRIILAIAVKFENVRLIDNITLTVK
HHHHHCCCCHHHHHHCCCEEEEEEEEEECCEEEEEEEEEEEC
>Mature Secondary Structure
MKIVTTVQEMQHITKELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPL
CCHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHCCHHHHHHHHCCCCCEEEEEEEECHH
QFGPNEDLDRYPRDIDRDENVAKENGVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGKQ
CCCCCCCHHHCCCCCCCCCCHHHHCCCCEEECCCHHHHCCCCCCHHHHHHHHHHHHCCCC
RPGHFAGVATVLMKLFNITLPTRAYFGMKDAQQVAVIEGFVADFNIPVIIVPVDIVREED
CCCHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHEECCC
GLAKSSRNVYLSQKERKEAPHLYRSLCMAKERIEAGERNAEIITTLVKEYIETYTKGTVD
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
YADLYAYPSLQVVDQIEGRIILAIAVKFENVRLIDNITLTVK
HHHHHCCCCHHHHHHCCCEEEEEEEEEECCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA