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The map label for this gene is hapR [H]

Identifier: 227080766

GI number: 227080766

Start: 569877

End: 570623

Strand: Reverse

Name: hapR [H]

Synonym: VCM66_0541

Alternate gene names: 227080766

Gene position: 570623-569877 (Counterclockwise)

Preceding gene: 227080767

Following gene: 227080764

Centisome position: 19.73

GC content: 46.99

Gene sequence:

>747_bases
ATGGACGCATCAATCGAAAAACGCCCTCGAACTCGGCTATCGCCTCAAAAACGCAAACTACAACTGATGGAAATCGCGTT
GGAAGTGTTTGCTAAACGCGGCATTGGTCGTGGTGGTCACGCAGATATTGCCGAGATTGCGCAAGTCTCCGTTGCAACAG
TGTTCAACTACTTCCCAACTCGTGAAGACTTGGTTGACGATGTGCTGAATTTTGTGGTTCGTCAGTACTCCAACTTCTTG
ACCGATCACATCGATCTTGATTTGGATGTGAAAACCAACCTACAAACTCTGTGCAAAGAGATGGTGAAATTGGCGATGAC
CGATTGTCACTGGCTCAAAGTCTGGTTTGAGTGGAGTGCTTCAACCCGTGACGAAGTTTGGCCACTGTTTGTTTCCACCA
ACCGAACTAACCAACTGCTGATCAGAAACATGTTTATGAAAGCGATGGAGCGTGGCGAATTGTGTGAGAAACACGATGTC
GATAACATGGCCAGCCTGTTCCACGGCATCTTCTACTCCATCTTCTTACAAGTGAACCGTTTAGGTGAACAAGAAGCAGT
GTATAAGTTGGCCGATAGCTACCTCAATATGCGTGTATCTATAAGAACTAGTTTCTTGGGCAGCACAAAGGGCGCATCCG
CGCCCTTTTTTGTTTTCAGATGGGTATCACTTCCAGCGGTAATAAATATACCTAAACGACTTGGTGTTGCAGGCCGGCGG
CAAATGAGTGAATCCCCACGAGCATAG

Upstream 100 bases:

>100_bases
TATGCACCATTACACTCATAGGGCTTTAAGTAGCAAATAACAAAATAATCATTAGAGCAAAATGCTCAATCAACAACTCA
ATTGGCAAGGATATACCCCT

Downstream 100 bases:

>100_bases
ATACACTCTGTGATTGGGGTGAGCAAATTCTGCCAACACCGCTACAGCTTCAAGTAGGAAATGGATAGAAGAGAAAATTA
TTCGCCTAAATTCTCCAAGC

Product: hemagglutinin/protease regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLADSYLNMRVSIRTSFLGSTKGASAPFFVFRWVSLPAVINIPKRLGVAGRR
QMSESPRA

Sequences:

>Translated_248_residues
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLADSYLNMRVSIRTSFLGSTKGASAPFFVFRWVSLPAVINIPKRLGVAGRR
QMSESPRA
>Mature_248_residues
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLADSYLNMRVSIRTSFLGSTKGASAPFFVFRWVSLPAVINIPKRLGVAGRR
QMSESPRA

Specific function: Regulatory protein of bacterial bioluminescence. It probably binds the autoinducer molecule and potentiates the transcription of the bioluminescence operon [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 28543; Mature: 28543

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
REDLVDDVLNFVVRQYSNFLTDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHEEEEEEECC
STRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDVDNMASLFHGIFYSIFLQVNR
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
LGEQEAVYKLADSYLNMRVSIRTSFLGSTKGASAPFFVFRWVSLPAVINIPKRLGVAGRR
CCHHHHHHHHHHHHHHEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHCHHHHH
QMSESPRA
HCCCCCCC
>Mature Secondary Structure
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
REDLVDDVLNFVVRQYSNFLTDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHEEEEEEECC
STRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDVDNMASLFHGIFYSIFLQVNR
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
LGEQEAVYKLADSYLNMRVSIRTSFLGSTKGASAPFFVFRWVSLPAVINIPKRLGVAGRR
CCHHHHHHHHHHHHHHEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHCHHHHH
QMSESPRA
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2160932; 8344950 [H]