Click here to switch to the map view.

The map label for this gene is yqeV [H]

Identifier: 226950381

GI number: 226950381

Start: 3381013

End: 3382311

Strand: Reverse

Name: yqeV [H]

Synonym: CLM_3350

Alternate gene names: 226950381

Gene position: 3382311-3381013 (Counterclockwise)

Preceding gene: 226950382

Following gene: 226950380

Centisome position: 81.4

GC content: 28.56

Gene sequence:

>1299_bases
ATGAAGGTTGCTTTTTCTACATTAGGATGTAGAGTAAATGTATATGAAACAGAAGCTATGACAGAAAAATTTATAAATCA
AGGTTATGAAATAGTGGATTTTAATGAAGTGGCTGATGTATATGTAATAAACACCTGTACGGTGACTAATATGGGTGATA
AAAAATCAAGACAGATGATAAGTAGAGGAAGAAGACAAAATTCAAAAGCTATAATTGCAGTAGTAGGTTGTTATTCTCAA
ATAGCTCCAGAAGAAGTATCTAAAATAGATGGCGTAGATGTAGTTCTAGGTACTAGAAATAAAGGTGATATAGTTTATTG
GGTAAATAGAGCTATGGAAGAAAAAAATCAAGTAATAGAAGTTAAAGATGTTCTTAGAAATAAAGAATTTGAAGAATTAA
ATATAGAAGAGTATAGAGATAAAACTAGAGCCTTTTTAAAAATACAGGATGGATGTAATAGATTTTGTTCTTATTGCTTG
ATACCTTTTGCAAGAGGAGCGGTATGTAGCAAAAAACCAGAAAAGATTATGGAAGAGGTCGAAAAACTTTCTAAGCATGG
ATTTAAAGAAATAATTTTATCTGGTATAGACATAGCTTCCTATGGTTTTGATTTAGAAGGAAAGTATAATTTAACATCTA
TATTAGAAGAGATAGATAAAGTAGAAGGTATTGAAAGAATAAGAATAGGCTCTATAGACCCAACTTTTTTTACAGAAGAA
GAAATAATAAGAATAAGTAAACTAAAGAGATTCTGTCCACATTTTCATTTGTCCCTTCAGAGCGGATGTAACGAAACTCT
AAAAAGAATGAATAGAAAATATACCGTAGAGCAGTATAAAGAGATAGTGCACAACTTAAGAACAAATATAGAATCTGTTT
CTATAACTACAGATATAATAGTAGGTTTCCCAGAAGAAACAGAAGAAGAGTTTAATAAAACCTATGAATTTTTAAGAGAT
ATAAAACTGTCTAAAATGCATGTATTTAAATTTAGCCCAAGAAAAGGTACTAGGGCAGAAGAAATGAAGAATCAAGTAGA
TGGTAAAATAAAAGAAGAAAGAAGTAATAAAATAATAAATTTAGATAAAGACCTTGAAAAAGAATTTATGAATAAATTTA
TTGAAAAAGAAATGCCGGTATTATATGAGCAGGAAACTAAAGAAAAAGGAATTTTTGAAGGATATACTCCAAATTACATA
AAGATATATTCTAAAAGCTCAAAGGATATTACTGGGGAAATAATAAATACAACGCTGAAAGAAGTTTCTAAGGATTTTAT
TAAAGGAGAAATTTATTAG

Upstream 100 bases:

>100_bases
TAGTAACTTTAGGGCCTAGAATATTTAGAACAGAAACAGCAGGTATAGTATGTGCTTCAATAATTTCATATGAATTAGGA
GATCTAGGAGGAAATATATA

Downstream 100 bases:

>100_bases
AGTAGAAGGATTTTTAATCTATTTATTGAATATTTCACTTAACAGGAGGTGATATAATGGAAAATTGTATTTTTTGTAAA
ATATTGAAGGGAGAAATACC

Product: RNA modification enzyme, MiaB family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MKVAFSTLGCRVNVYETEAMTEKFINQGYEIVDFNEVADVYVINTCTVTNMGDKKSRQMISRGRRQNSKAIIAVVGCYSQ
IAPEEVSKIDGVDVVLGTRNKGDIVYWVNRAMEEKNQVIEVKDVLRNKEFEELNIEEYRDKTRAFLKIQDGCNRFCSYCL
IPFARGAVCSKKPEKIMEEVEKLSKHGFKEIILSGIDIASYGFDLEGKYNLTSILEEIDKVEGIERIRIGSIDPTFFTEE
EIIRISKLKRFCPHFHLSLQSGCNETLKRMNRKYTVEQYKEIVHNLRTNIESVSITTDIIVGFPEETEEEFNKTYEFLRD
IKLSKMHVFKFSPRKGTRAEEMKNQVDGKIKEERSNKIINLDKDLEKEFMNKFIEKEMPVLYEQETKEKGIFEGYTPNYI
KIYSKSSKDITGEIINTTLKEVSKDFIKGEIY

Sequences:

>Translated_432_residues
MKVAFSTLGCRVNVYETEAMTEKFINQGYEIVDFNEVADVYVINTCTVTNMGDKKSRQMISRGRRQNSKAIIAVVGCYSQ
IAPEEVSKIDGVDVVLGTRNKGDIVYWVNRAMEEKNQVIEVKDVLRNKEFEELNIEEYRDKTRAFLKIQDGCNRFCSYCL
IPFARGAVCSKKPEKIMEEVEKLSKHGFKEIILSGIDIASYGFDLEGKYNLTSILEEIDKVEGIERIRIGSIDPTFFTEE
EIIRISKLKRFCPHFHLSLQSGCNETLKRMNRKYTVEQYKEIVHNLRTNIESVSITTDIIVGFPEETEEEFNKTYEFLRD
IKLSKMHVFKFSPRKGTRAEEMKNQVDGKIKEERSNKIINLDKDLEKEFMNKFIEKEMPVLYEQETKEKGIFEGYTPNYI
KIYSKSSKDITGEIINTTLKEVSKDFIKGEIY
>Mature_432_residues
MKVAFSTLGCRVNVYETEAMTEKFINQGYEIVDFNEVADVYVINTCTVTNMGDKKSRQMISRGRRQNSKAIIAVVGCYSQ
IAPEEVSKIDGVDVVLGTRNKGDIVYWVNRAMEEKNQVIEVKDVLRNKEFEELNIEEYRDKTRAFLKIQDGCNRFCSYCL
IPFARGAVCSKKPEKIMEEVEKLSKHGFKEIILSGIDIASYGFDLEGKYNLTSILEEIDKVEGIERIRIGSIDPTFFTEE
EIIRISKLKRFCPHFHLSLQSGCNETLKRMNRKYTVEQYKEIVHNLRTNIESVSITTDIIVGFPEETEEEFNKTYEFLRD
IKLSKMHVFKFSPRKGTRAEEMKNQVDGKIKEERSNKIINLDKDLEKEFMNKFIEKEMPVLYEQETKEKGIFEGYTPNYI
KIYSKSSKDITGEIINTTLKEVSKDFIKGEIY

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI28872782, Length=392, Percent_Identity=29.0816326530612, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI28872784, Length=392, Percent_Identity=29.0816326530612, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI93277076, Length=450, Percent_Identity=27.5555555555556, Blast_Score=163, Evalue=2e-40,
Organism=Escherichia coli, GI1786882, Length=442, Percent_Identity=27.3755656108597, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1787057, Length=403, Percent_Identity=25.5583126550869, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17553146, Length=420, Percent_Identity=28.5714285714286, Blast_Score=164, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI71996771, Length=285, Percent_Identity=27.719298245614, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21356207, Length=418, Percent_Identity=26.555023923445, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI19922432, Length=439, Percent_Identity=26.6514806378132, Blast_Score=153, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 50182; Mature: 50182

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAFSTLGCRVNVYETEAMTEKFINQGYEIVDFNEVADVYVINTCTVTNMGDKKSRQMI
CEEEEEECCCEEEEEEHHHHHHHHHHCCCEEEECCCCCCEEEEEEEEECCCCCHHHHHHH
SRGRRQNSKAIIAVVGCYSQIAPEEVSKIDGVDVVLGTRNKGDIVYWVNRAMEEKNQVIE
HHHCCCCCCEEEEEECHHHHCCHHHHHHCCCCEEEEECCCCCCEEEEHHHHHHHHHCEEH
VKDVLRNKEFEELNIEEYRDKTRAFLKIQDGCNRFCSYCLIPFARGAVCSKKPEKIMEEV
HHHHHCCCCCCCCCHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
EKLSKHGFKEIILSGIDIASYGFDLEGKYNLTSILEEIDKVEGIERIRIGSIDPTFFTEE
HHHHHCCHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHH
EIIRISKLKRFCPHFHLSLQSGCNETLKRMNRKYTVEQYKEIVHNLRTNIESVSITTDII
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEEE
VGFPEETEEEFNKTYEFLRDIKLSKMHVFKFSPRKGTRAEEMKNQVDGKIKEERSNKIIN
EECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHCCCEEE
LDKDLEKEFMNKFIEKEMPVLYEQETKEKGIFEGYTPNYIKIYSKSSKDITGEIINTTLK
CCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHH
EVSKDFIKGEIY
HHHHHHHCCCCC
>Mature Secondary Structure
MKVAFSTLGCRVNVYETEAMTEKFINQGYEIVDFNEVADVYVINTCTVTNMGDKKSRQMI
CEEEEEECCCEEEEEEHHHHHHHHHHCCCEEEECCCCCCEEEEEEEEECCCCCHHHHHHH
SRGRRQNSKAIIAVVGCYSQIAPEEVSKIDGVDVVLGTRNKGDIVYWVNRAMEEKNQVIE
HHHCCCCCCEEEEEECHHHHCCHHHHHHCCCCEEEEECCCCCCEEEEHHHHHHHHHCEEH
VKDVLRNKEFEELNIEEYRDKTRAFLKIQDGCNRFCSYCLIPFARGAVCSKKPEKIMEEV
HHHHHCCCCCCCCCHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
EKLSKHGFKEIILSGIDIASYGFDLEGKYNLTSILEEIDKVEGIERIRIGSIDPTFFTEE
HHHHHCCHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHH
EIIRISKLKRFCPHFHLSLQSGCNETLKRMNRKYTVEQYKEIVHNLRTNIESVSITTDII
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEEE
VGFPEETEEEFNKTYEFLRDIKLSKMHVFKFSPRKGTRAEEMKNQVDGKIKEERSNKIIN
EECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHCCCEEE
LDKDLEKEFMNKFIEKEMPVLYEQETKEKGIFEGYTPNYIKIYSKSSKDITGEIINTTLK
CCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHH
EVSKDFIKGEIY
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9023197; 9384377 [H]