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The map label for this gene is xpt [H]

Identifier: 226947548

GI number: 226947548

Start: 406235

End: 406807

Strand: Direct

Name: xpt [H]

Synonym: CLM_0385

Alternate gene names: 226947548

Gene position: 406235-406807 (Clockwise)

Preceding gene: 226947547

Following gene: 226947549

Centisome position: 9.78

GC content: 30.37

Gene sequence:

>573_bases
GTGGAAAAATTACAAAATCGTATTTTACAAGAAGGTCATGCATTATCTGAAACTGTATTAAAGGTGGATTCTTTTTTAAA
TCATCAAGTAGATCCAGATCTAATGTATGAAATAGGAACTTATTTTAAAAATTATTTTAAAGAACATAAAATCACAAAGG
TATTTACAATTGAAAGTTCAGGAATTGCTCCAGCTGTTATGACTGCAATGCAAATGAATTTGCCAATGGTAATCTTAAAA
AAACAAGCATCAAAAATTTTAAATGGAGATGTTTATCAAACCACTGTACATTCATTTACAAAGGGATTGGATTATGAATT
AACATTATCTAAAAAATATATTGCCAAAGAGGACAATATATTAATTATAGATGACTTTTTAGCCAATGGAGAAGCAGCAT
TAGGAGCTGCACGTTTGGTTCAAGAGGCAGGAGCTAAAGTTGCTGGAATGGGCATTGTTATTGAAAAATCATTCCAACCG
GGAAGAAAAATGTTACAAGAAAAAGGATATGATGTGTATTCACTAGCACGTATAGCAAAACTTGAAAAAGGCTTAATTGA
ATTTGTAAAGTAA

Upstream 100 bases:

>100_bases
ATGATTTTTTCATCAGGAATTTCAACTGGAACAATTGTAGCTTTATTATTAAATGTAATATTAAAAGAAAAAGAATAAGG
AATTTTACGGGGTGATATAA

Downstream 100 bases:

>100_bases
AAGTATTTTAATTATTGAATTCTAAAATAGTACTTATTGGTAATTATGTAAGATTATATTTAAAAATAGATTTAATTTTA
ATATGGCGAAGATAAAAAAC

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase 1 [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MEKLQNRILQEGHALSETVLKVDSFLNHQVDPDLMYEIGTYFKNYFKEHKITKVFTIESSGIAPAVMTAMQMNLPMVILK
KQASKILNGDVYQTTVHSFTKGLDYELTLSKKYIAKEDNILIIDDFLANGEAALGAARLVQEAGAKVAGMGIVIEKSFQP
GRKMLQEKGYDVYSLARIAKLEKGLIEFVK

Sequences:

>Translated_190_residues
MEKLQNRILQEGHALSETVLKVDSFLNHQVDPDLMYEIGTYFKNYFKEHKITKVFTIESSGIAPAVMTAMQMNLPMVILK
KQASKILNGDVYQTTVHSFTKGLDYELTLSKKYIAKEDNILIIDDFLANGEAALGAARLVQEAGAKVAGMGIVIEKSFQP
GRKMLQEKGYDVYSLARIAKLEKGLIEFVK
>Mature_190_residues
MEKLQNRILQEGHALSETVLKVDSFLNHQVDPDLMYEIGTYFKNYFKEHKITKVFTIESSGIAPAVMTAMQMNLPMVILK
KQASKILNGDVYQTTVHSFTKGLDYELTLSKKYIAKEDNILIIDDFLANGEAALGAARLVQEAGAKVAGMGIVIEKSFQP
GRKMLQEKGYDVYSLARIAKLEKGLIEFVK

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR010079 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 21293; Mature: 21293

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLQNRILQEGHALSETVLKVDSFLNHQVDPDLMYEIGTYFKNYFKEHKITKVFTIESS
CHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVMTAMQMNLPMVILKKQASKILNGDVYQTTVHSFTKGLDYELTLSKKYIAKEDNI
CCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECHHHHCCCCCE
LIIDDFLANGEAALGAARLVQEAGAKVAGMGIVIEKSFQPGRKMLQEKGYDVYSLARIAK
EEEECCCCCCCHHHHHHHHHHHHCCCEECCEEEEECCCCHHHHHHHHCCCCHHHHHHHHH
LEKGLIEFVK
HHHHHHHHCC
>Mature Secondary Structure
MEKLQNRILQEGHALSETVLKVDSFLNHQVDPDLMYEIGTYFKNYFKEHKITKVFTIESS
CHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVMTAMQMNLPMVILKKQASKILNGDVYQTTVHSFTKGLDYELTLSKKYIAKEDNI
CCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECHHHHCCCCCE
LIIDDFLANGEAALGAARLVQEAGAKVAGMGIVIEKSFQPGRKMLQEKGYDVYSLARIAK
EEEECCCCCCCHHHHHHHHHHHHCCCEECCEEEEECCCCHHHHHHHHCCCCHHHHHHHHH
LEKGLIEFVK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA