| Definition | Clostridium botulinum A2 str. Kyoto chromosome, complete genome. |
|---|---|
| Accession | NC_012563 |
| Length | 4,155,278 |
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The map label for this gene is secA [H]
Identifier: 226947395
GI number: 226947395
Start: 201710
End: 204217
Strand: Direct
Name: secA [H]
Synonym: CLM_0221
Alternate gene names: 226947395
Gene position: 201710-204217 (Clockwise)
Preceding gene: 226947394
Following gene: 226947396
Centisome position: 4.85
GC content: 30.94
Gene sequence:
>2508_bases ATGGGAATTTTAAATAAAATATTTGGTACATATAGTGAAAGAGAACTTAGAAGAGTTAACCCTATAGTAAACAAAATAGA AGCTTTAGATGAAAAAATGCAATCCTTAAAAGATGAAGATTTTAAGCTAAAAACTGAAGAATTTAAAAGTAGATTAGAAA AAGGGGAAAAACTAGATGATATTTTACCAGAAGCTTTTGCCTTAGTTAGAGAAGCGGCACATAGAACCATAGGACTTAAA CATTATAGAGAACAATTAATAGGCGGTGTAGTATTACACCAAGGAAGAATTGGAGAAATGAAAACCGGTGAAGGTAAAAC TTTAGTTGCTACATTGCCAGCCTATGTAAATGCATTAACAGGAAAAGGGGTACATATAGTTACAGTTAATGATTACTTGG CAAAAAGAGATAGGGATTTAATGGCTCCGGTATATGAATTTTTAGGGCTAAAAGTAGGAGTTATTTTGCATAATTTAAAT AATGAAGAAAGACAAGAAGCTTATGGTTCAGATATAACTTATGGAACAAATAGTGAATTTGGCTTTGATTATTTAAGAGA TAATATGGTAGTTTATAAAGAAGAAAGAGTTCAAAGAAAGTTAAACTTTTCAATTGTGGATGAAGTGGACTCTATATTAA TAGATGAAGCTAGAACTCCATTAATAATATCAGGTCAAGGGGAGAAGTCTACAGAGTTTTATAAGGTTGCAGATTATTTC ACTAAATCTCTAATAGCTGAAAAAGATTTTACAATAGATGAAAAAGCTAATTCAGCTATGCTTACAGATGAAGGTGTTAA TAAAGCAGAGAATTTCTTTAAAGTAGATAACTATGCTGATGCAGAAAACATGGAAATACAACACCATGTAGTTCAAGCTT TAAAAGCTAACTATGTAATGAAAAAAGATAAAGATTATATGATTAAGGATGGAGAAATTCTAATAGTTGATGAGTTTACA GGAAGAGCTATGGAAGGAAGAAGATATAGCGATGGATTGCACCAAGCTATAGAAGCTAAAGAAGGCGTTAGAGTAGAAAG AGAATCTAAAACTTTAGCTACAATAACTTATCAAAACTATTTTAGAATGTACAATAAATTGTCTGGTATGACAGGAACTG CTCAAACAGAAGAAAATGAATTTAGAGAAATCTATGGATTAGATGTAATTGTAATACCTACACATGAGCCTATAGCAAGA ATAGATAATGCTGATGTAGTATATAAATCAGAAAAGGGTAAATTTAAAGCCATAGTTGATGAAATAGTAGAAAGATATAA AAAAGGTCAACCAATGCTAGTAGGTACAGTAAGCATAGAAAAATCAGAAATGTTATCCTCTATGTTAAAGAAAAAAGGAG TACCTCATCAAGTATTAAATGCTAAATATCATGAAAAAGAAGCGGAAATAATATCTCATGCAGGGGAATATGGGATGGTT ACAATAGCCACTAATATGGCAGGCCGTGGTACAGATATAAAGCTTACTAAGGAAGCTGAAGAAGCAGGCGGGCTTATGAT TATAGGTACAGAAAGACATGAGTCTAGAAGAATAGACAACCAATTAAGAGGACGTTCTGGTCGTCAAGGAGATCCTGGTG AATCAAGATTTTTTGTATCTTTAGAAGATGATTTAATGAGAATATTTGGTTCAGAAAGAATACAAGGAATAGTTGATAAA TTAGGACTCGCTGAAGATGAAGCTATAGAAAGTAAAATGGTAAGTTCAGCTATAGAAAGTGCTCAAAAGAAGGTAGAAGG AAATAACTTTGATATAAGAAAAACTTTATTACAATATGATGATGTAATAAATAAACAAAGAGAAATAATCTATAAACAAA GAAGTGAGGTTTTAGAGGGAGAAGACTTAAAGGATCAAATAAGAGATATGATAAGGGATGTGGTTTATACTGCAGTAAAT TCTCATATTTCAGGAGTAGAAGAAGAGTTTGAAACAGAACTTCAAAATCTTGTTAATTATTTAGAAGACATATGCTTACC AAAGGCCTTAGTAAAGGTAAAAGATATAAGTAATTTATCAGATGAAGAAATAAAAGAAAAATTATTAGAAGCAGTAGAAA ATATATATAGCCGCAAAGAAAAAGAAATTGGGGAAGAACAAATAAGAGAAATAGAAAGAGTAATATTGCTTAGGGTTGTA GATACTAAATGGATGGATCATATAGATGATATGGATCACTTAAAACAAGGTATAGGACTAAGAGCATATAGACAACAAGA TCCAGTTCAAGCATATCAATTTGAAGGTAGTGAAATGTTTGAGGAAATGATCTATAACATTAAAGTAGATACAGTAAGAT ATTTATTCCATGTAGAAGTAGAAAAAGCACCTGAAAGAGAGAAAGTGGCAAAAGAAACATCAACTAATTATGATGAAGAT TCAGTAAAAAAACAACCTATAAAAAAAGAAAATAGAATAGGTAGAAATGATATGTGTCCTTGCGGAAGTGGAAAAAAATA TAAAAATTGTTGTGGTAGAATGGCATAA
Upstream 100 bases:
>100_bases ACATAATTATTATTCTAAAAAGTTGAATGGAATTTAGTTAAATGATATAATTTATAAAGTTAAGACCTATAAAATTTGAT AAATAGTGAGGATGAATAAT
Downstream 100 bases:
>100_bases AAATATATTATAATAAAACCGGAAACTTTATTTGGTTTCTGGTTTTATAACCTTTAAGGCACATTCAAATAAATAACAAG TCAGTATGACAGTATATTTT
Product: preprotein translocase subunit SecA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 835; Mature: 834
Protein sequence:
>835_residues MGILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDDILPEAFALVREAAHRTIGLK HYREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALTGKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLN NEERQEAYGSDITYGTNSEFGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYF TKSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVMKKDKDYMIKDGEILIVDEFT GRAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNYFRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIAR IDNADVVYKSEKGKFKAIVDEIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMV TIATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVSLEDDLMRIFGSERIQGIVDK LGLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYDDVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVVYTAVN SHISGVEEEFETELQNLVNYLEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYSRKEKEIGEEQIREIERVILLRVV DTKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEVEKAPEREKVAKETSTNYDED SVKKQPIKKENRIGRNDMCPCGSGKKYKNCCGRMA
Sequences:
>Translated_835_residues MGILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDDILPEAFALVREAAHRTIGLK HYREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALTGKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLN NEERQEAYGSDITYGTNSEFGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYF TKSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVMKKDKDYMIKDGEILIVDEFT GRAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNYFRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIAR IDNADVVYKSEKGKFKAIVDEIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMV TIATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVSLEDDLMRIFGSERIQGIVDK LGLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYDDVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVVYTAVN SHISGVEEEFETELQNLVNYLEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYSRKEKEIGEEQIREIERVILLRVV DTKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEVEKAPEREKVAKETSTNYDED SVKKQPIKKENRIGRNDMCPCGSGKKYKNCCGRMA >Mature_834_residues GILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDDILPEAFALVREAAHRTIGLKH YREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALTGKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLNN EERQEAYGSDITYGTNSEFGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYFT KSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVMKKDKDYMIKDGEILIVDEFTG RAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNYFRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIARI DNADVVYKSEKGKFKAIVDEIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMVT IATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVSLEDDLMRIFGSERIQGIVDKL GLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYDDVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVVYTAVNS HISGVEEEFETELQNLVNYLEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYSRKEKEIGEEQIREIERVILLRVVD TKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEVEKAPEREKVAKETSTNYDEDS VKKQPIKKENRIGRNDMCPCGSGKKYKNCCGRMA
Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo
COG id: COG0653
COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the secA family [H]
Homologues:
Organism=Escherichia coli, GI1786287, Length=897, Percent_Identity=49.1638795986622, Blast_Score=847, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004027 - InterPro: IPR000185 - InterPro: IPR020937 - InterPro: IPR011115 - InterPro: IPR014018 - InterPro: IPR011130 - InterPro: IPR011116 [H]
Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]
EC number: NA
Molecular weight: Translated: 95584; Mature: 95453
Theoretical pI: Translated: 5.08; Mature: 5.08
Prosite motif: PS01312 SECA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDD CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHCCCHHHH ILPEAFALVREAAHRTIGLKHYREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALT HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEHHHHHHHHC GKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLNNEERQEAYGSDITYGTNSEF CCCEEEEEECHHHHHCCCHHHHHHHHHHHHHHHHHEECCCCHHHHHHCCCCCCCCCCCCC GFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYF CHHHHHCCEEEEHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHH TKSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVM HHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHE KKDKDYMIKDGEILIVDEFTGRAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNY ECCCCCEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCEEEEEHHHHH FRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIARIDNADVVYKSEKGKFKAIVD HHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEECCCCHHHHCCCCCEEEECCCCHHHHHHH EIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMV HHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCEE TIATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVS EEEECCCCCCCCEEEECCHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEE LEDDLMRIFGSERIQGIVDKLGLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYD EHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH DVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVVYTAVNSHISGVEEEFETELQNLVNY HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH LEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYSRKEKEIGEEQIREIERVILLRVV HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH DTKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEV HHHHHHHHCCHHHHHHCCCCCHHCCCCCCHHHHCCCHHHHHHHHHHCCHHHEEEEEEEEH EKAPEREKVAKETSTNYDEDSVKKQPIKKENRIGRNDMCPCGSGKKYKNCCGRMA HCCCCHHHHHHHHCCCCCHHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHCCCC >Mature Secondary Structure GILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDD CCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHCCCHHHH ILPEAFALVREAAHRTIGLKHYREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALT HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEHHHHHHHHC GKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLNNEERQEAYGSDITYGTNSEF CCCEEEEEECHHHHHCCCHHHHHHHHHHHHHHHHHEECCCCHHHHHHCCCCCCCCCCCCC GFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYF CHHHHHCCEEEEHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHH TKSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVM HHHHHHCCCCCCCCCCCCCEECCCCCCHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHE KKDKDYMIKDGEILIVDEFTGRAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNY ECCCCCEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCEEEEEHHHHH FRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIARIDNADVVYKSEKGKFKAIVD HHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEECCCCHHHHCCCCCEEEECCCCHHHHHHH EIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMV HHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCEE TIATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVS EEEECCCCCCCCEEEECCHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEE LEDDLMRIFGSERIQGIVDKLGLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYD EHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH DVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVVYTAVNSHISGVEEEFETELQNLVNY HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH LEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYSRKEKEIGEEQIREIERVILLRVV HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH DTKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEV HHHHHHHHCCHHHHHHCCCCCHHCCCCCCHHHHCCCHHHHHHHHHHCCHHHEEEEEEEEH EKAPEREKVAKETSTNYDEDSVKKQPIKKENRIGRNDMCPCGSGKKYKNCCGRMA HCCCCHHHHHHHHCCCCCHHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA