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The map label for this gene is yhdP [H]

Identifier: 226225289

GI number: 226225289

Start: 2783941

End: 2785275

Strand: Reverse

Name: yhdP [H]

Synonym: Lm4b_02712

Alternate gene names: 226225289

Gene position: 2785275-2783941 (Counterclockwise)

Preceding gene: 226225290

Following gene: 226225288

Centisome position: 95.63

GC content: 40.0

Gene sequence:

>1335_bases
ATGAACCCTGACCCCGAGAGTCAGCAGATTATCTTGCAGTTAATTCTTATTGTGGTGTTGACGATGCTCAACGCATTCTT
TGCCTCAGCAGAGATGGCCCTTGTATCATTGAACAAAAATCGTGTAAAAAGCCAGGCAGAAACCGGTGATAAAAAAGCGG
TTATGCTAGCTAAACTCGTAGATGATCCAAGTAAATTTCTAGCTACTATTCAAGTTGGTATTACGCTTGCGGGATTCTTC
TCCAGTGCGTCAGCTGCCACTAGTATTGCGACTAGACTTGAATCTGTTTTTGGAGGAAGTAGTTTTGCGAAAGAGTTATC
CATTATCGTCGTAACTATTGTGTTATCATATATCACGTTAGTTTTCGGTGAACTTTATCCAAAACGTTTAGCACTTCAAA
AATCAGAAAAAATTGCCCGTGTTTCTGTACGACCAATCATGGCAGTTGGTGTTGTGCTTCGTCCGTTCGTGAAATTCCTG
TCTTTTTCAACCGATATTCTTGTGAAATTAACGAGAATGGAGAAAAATACGGATAATGAAAAAATGACGCGAGAGGAAAT
GCAGCTACTGATTGAAACCGGTCGACGTGACGGTGTAATTGAGGTAGAAGAATTACAAATGCTTCGTGGTGTATTTGAAA
TGGATAATAAATATGCGCGTGAAGTGATGGTGCCACGAACAGATGCGTTTATGATTGATGCCGAAACAGAGTCGGAAGAA
CTTTGTGACGCATTATTAAGTGAGAATTTTTCAAGGGTTCCCGTTTTTACAGGCGATCAGGACTCGGTGCTAGGTATTCT
GCATATGAAAGATTTTTTTGCGGAAGCGAGAAAGTCAGGTTTTGAAAACATTGATGTGAAGGCGCTCGTTAAAGACGCGT
ATTTTGCGCAAGAGACGATGTTTATTGACGATCTACTTAAAAATATGCAAAGAACTAGAAATCAAATGGCTATTTTAATG
GATGAATACGGTGGTGTTGCTGGTATTGTCACTGTAGAAGATTTATTAGAAGAAATTGTTGGCGAGATTGACGATGAAAA
TGATGTGTTTTCGGATGAAGTGAAGAAAATTGATGAGACGACATTTATCGTAGAAGGTCGCATGCCGCTTGATGATTTCA
ATGAAATGTTTCACGTGGAACTTCCATCACGTGGCGTAGATACTGTGGCTGGATTTGTGCTTACTTTAACTGGGACAATT
CCAGAAGAAGATGATAAAGTAGTAGTAGAATACGGTACACTTCGATTTACAGTAGAAGAAATGAATGATGCCAGACTGGT
TTCGGTTCGTGTCGAAAAAGACATCCGAACAAGCGAACTTGAACAGATGGCTTAA

Upstream 100 bases:

>100_bases
GGTGGCGTGATAAAATTTTCTTAACCGGCAAATTGTCCGGAATATTTAGAGAAAATGCATGGTCGTTTTCTTGATGAAAA
TAAGGAGTGGAGAGTTTCAT

Downstream 100 bases:

>100_bases
TGATAAAAATAGGAGTGCGGTATGAGAAATCTGTCCGCACTTTTTTCTTAGGAATGAGGTTTTTAAAATGCCAAATATTA
AAGAAATAGCCAAATTAGCG

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MNPDPESQQIILQLILIVVLTMLNAFFASAEMALVSLNKNRVKSQAETGDKKAVMLAKLVDDPSKFLATIQVGITLAGFF
SSASAATSIATRLESVFGGSSFAKELSIIVVTIVLSYITLVFGELYPKRLALQKSEKIARVSVRPIMAVGVVLRPFVKFL
SFSTDILVKLTRMEKNTDNEKMTREEMQLLIETGRRDGVIEVEELQMLRGVFEMDNKYAREVMVPRTDAFMIDAETESEE
LCDALLSENFSRVPVFTGDQDSVLGILHMKDFFAEARKSGFENIDVKALVKDAYFAQETMFIDDLLKNMQRTRNQMAILM
DEYGGVAGIVTVEDLLEEIVGEIDDENDVFSDEVKKIDETTFIVEGRMPLDDFNEMFHVELPSRGVDTVAGFVLTLTGTI
PEEDDKVVVEYGTLRFTVEEMNDARLVSVRVEKDIRTSELEQMA

Sequences:

>Translated_444_residues
MNPDPESQQIILQLILIVVLTMLNAFFASAEMALVSLNKNRVKSQAETGDKKAVMLAKLVDDPSKFLATIQVGITLAGFF
SSASAATSIATRLESVFGGSSFAKELSIIVVTIVLSYITLVFGELYPKRLALQKSEKIARVSVRPIMAVGVVLRPFVKFL
SFSTDILVKLTRMEKNTDNEKMTREEMQLLIETGRRDGVIEVEELQMLRGVFEMDNKYAREVMVPRTDAFMIDAETESEE
LCDALLSENFSRVPVFTGDQDSVLGILHMKDFFAEARKSGFENIDVKALVKDAYFAQETMFIDDLLKNMQRTRNQMAILM
DEYGGVAGIVTVEDLLEEIVGEIDDENDVFSDEVKKIDETTFIVEGRMPLDDFNEMFHVELPSRGVDTVAGFVLTLTGTI
PEEDDKVVVEYGTLRFTVEEMNDARLVSVRVEKDIRTSELEQMA
>Mature_444_residues
MNPDPESQQIILQLILIVVLTMLNAFFASAEMALVSLNKNRVKSQAETGDKKAVMLAKLVDDPSKFLATIQVGITLAGFF
SSASAATSIATRLESVFGGSSFAKELSIIVVTIVLSYITLVFGELYPKRLALQKSEKIARVSVRPIMAVGVVLRPFVKFL
SFSTDILVKLTRMEKNTDNEKMTREEMQLLIETGRRDGVIEVEELQMLRGVFEMDNKYAREVMVPRTDAFMIDAETESEE
LCDALLSENFSRVPVFTGDQDSVLGILHMKDFFAEARKSGFENIDVKALVKDAYFAQETMFIDDLLKNMQRTRNQMAILM
DEYGGVAGIVTVEDLLEEIVGEIDDENDVFSDEVKKIDETTFIVEGRMPLDDFNEMFHVELPSRGVDTVAGFVLTLTGTI
PEEDDKVVVEYGTLRFTVEEMNDARLVSVRVEKDIRTSELEQMA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=391, Percent_Identity=31.2020460358056, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI40068053, Length=376, Percent_Identity=24.468085106383, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI40068055, Length=376, Percent_Identity=24.468085106383, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI94681046, Length=292, Percent_Identity=26.027397260274, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1790664, Length=419, Percent_Identity=20.5250596658711, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI145693175, Length=393, Percent_Identity=25.4452926208651, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1786879, Length=255, Percent_Identity=30.9803921568627, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788119, Length=244, Percent_Identity=32.3770491803279, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082033, Length=253, Percent_Identity=24.5059288537549, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49768; Mature: 49768

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPDPESQQIILQLILIVVLTMLNAFFASAEMALVSLNKNRVKSQAETGDKKAVMLAKLV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCHHHHHHHHHH
DDPSKFLATIQVGITLAGFFSSASAATSIATRLESVFGGSSFAKELSIIVVTIVLSYITL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VFGELYPKRLALQKSEKIARVSVRPIMAVGVVLRPFVKFLSFSTDILVKLTRMEKNTDNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHH
KMTREEMQLLIETGRRDGVIEVEELQMLRGVFEMDNKYAREVMVPRTDAFMIDAETESEE
HHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEECCCCHHH
LCDALLSENFSRVPVFTGDQDSVLGILHMKDFFAEARKSGFENIDVKALVKDAYFAQETM
HHHHHHHCCCCCCCEEECCCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
FIDDLLKNMQRTRNQMAILMDEYGGVAGIVTVEDLLEEIVGEIDDENDVFSDEVKKIDET
HHHHHHHHHHHHHHHHEEEEHHCCCEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHCCC
TFIVEGRMPLDDFNEMFHVELPSRGVDTVAGFVLTLTGTIPEEDDKVVVEYGTLRFTVEE
EEEEECCCCHHHHCCEEEEECCCCCHHHHHHHHHEEECCCCCCCCEEEEEECEEEEEEEC
MNDARLVSVRVEKDIRTSELEQMA
CCCCEEEEEEECCCCCHHHHHHCC
>Mature Secondary Structure
MNPDPESQQIILQLILIVVLTMLNAFFASAEMALVSLNKNRVKSQAETGDKKAVMLAKLV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCHHHHHHHHHH
DDPSKFLATIQVGITLAGFFSSASAATSIATRLESVFGGSSFAKELSIIVVTIVLSYITL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VFGELYPKRLALQKSEKIARVSVRPIMAVGVVLRPFVKFLSFSTDILVKLTRMEKNTDNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHH
KMTREEMQLLIETGRRDGVIEVEELQMLRGVFEMDNKYAREVMVPRTDAFMIDAETESEE
HHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEECCCCHHH
LCDALLSENFSRVPVFTGDQDSVLGILHMKDFFAEARKSGFENIDVKALVKDAYFAQETM
HHHHHHHCCCCCCCEEECCCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
FIDDLLKNMQRTRNQMAILMDEYGGVAGIVTVEDLLEEIVGEIDDENDVFSDEVKKIDET
HHHHHHHHHHHHHHHHEEEEHHCCCEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHCCC
TFIVEGRMPLDDFNEMFHVELPSRGVDTVAGFVLTLTGTIPEEDDKVVVEYGTLRFTVEE
EEEEECCCCHHHHCCEEEEECCCCCHHHHHHHHHEEECCCCCCCCEEEEEECEEEEEEEC
MNDARLVSVRVEKDIRTSELEQMA
CCCCEEEEEEECCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]