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The map label for this gene is ccpB [H]

Identifier: 226225288

GI number: 226225288

Start: 2782917

End: 2783873

Strand: Reverse

Name: ccpB [H]

Synonym: Lm4b_02711

Alternate gene names: 226225288

Gene position: 2783873-2782917 (Counterclockwise)

Preceding gene: 226225289

Following gene: 226225283

Centisome position: 95.58

GC content: 40.65

Gene sequence:

>957_bases
ATGCCAAATATTAAAGAAATAGCCAAATTAGCGGGAGTTTCAGTGACGACAGTATCACGTGTGCTCAATAATCATCCGTA
TGTTGCGGAGGAGAAAAGAGCCCGTGTGCAAGCTGTTATTGATGAATTAGATTATTCTCCTAACCGTAGCGCCATGGATT
TAGCGCGTGGGAAAACAAATACGGTTGGCGTGATTATACCTTATAATGATCACCCGTGGTTTGACAAAATTGTAAATGGT
ATTTTGGAAGTAGCTTTTAAAAACCGTTATTCGGTGACACTTTTTCCAACAGGATATGATCCGAAAGAAGAAGAAAAGTA
CTTGATGCGTCTTAAAACGAAACAGGTGGATGGCCTGATTATTACTTCGCGTGCCAATAATTGGGACGTGATTTTGCCGT
ACCTAGCGTATGGACCGATTATTGCGTGCGAGTATGTGGAATCAAAAGAGGTATCGTGCTCTTATATTGACCGCGTGAAA
GCATACCGGGCTGGATTTCAGTTTTTGGAAGATGAAGGTTATAAAAAAGTGGCTTTTACAGCGGGGAGAGCATCGCGTGA
AAGTACGAGTACATATGGAAAAATCAATGCTTATGAGCAAGTTTTTGGTTCAGTGGGTGATAATCGGTTTCTAAGTGAAT
GTTATACGCTTGAAGATGGTTTGAAGGCTGGGGAGCATTTTTTTGCAGAGGGGAAAGACTGGCCTGATGCGATTTATGCG
AATGGTGACGAGGTTGCGGCAGGGGTTATGTATCACGTGAAAAAACTCGGCTTGCGTGTTCCGGAAGATGTCGCTATTTT
AGGGCAAGAAAATCTCCCAATTGGTAAGGTTTTAGAAATCACAACGCTTGATCATAACCTAAAAAAATTGGGAGAAAATG
CTTTTACTATTTTTGAACAAGGTAAATTGCAAAGAATTAAAGTGGAGCATGAATTGATTAGAAGGAAAACAGTTTAA

Upstream 100 bases:

>100_bases
ATCCGAACAAGCGAACTTGAACAGATGGCTTAATGATAAAAATAGGAGTGCGGTATGAGAAATCTGTCCGCACTTTTTTC
TTAGGAATGAGGTTTTTAAA

Downstream 100 bases:

>100_bases
AAAATTATTTGCCAATTAAAGTTAGTTTGGCAATGTTTTCCGCCGTGCGTTCGAGGTTCTTTGTTGTATTTTCGAAAAGA
GTGGGTAAATCTGTTATTTC

Product: transcriptional regulator (LacI family)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MPNIKEIAKLAGVSVTTVSRVLNNHPYVAEEKRARVQAVIDELDYSPNRSAMDLARGKTNTVGVIIPYNDHPWFDKIVNG
ILEVAFKNRYSVTLFPTGYDPKEEEKYLMRLKTKQVDGLIITSRANNWDVILPYLAYGPIIACEYVESKEVSCSYIDRVK
AYRAGFQFLEDEGYKKVAFTAGRASRESTSTYGKINAYEQVFGSVGDNRFLSECYTLEDGLKAGEHFFAEGKDWPDAIYA
NGDEVAAGVMYHVKKLGLRVPEDVAILGQENLPIGKVLEITTLDHNLKKLGENAFTIFEQGKLQRIKVEHELIRRKTV

Sequences:

>Translated_318_residues
MPNIKEIAKLAGVSVTTVSRVLNNHPYVAEEKRARVQAVIDELDYSPNRSAMDLARGKTNTVGVIIPYNDHPWFDKIVNG
ILEVAFKNRYSVTLFPTGYDPKEEEKYLMRLKTKQVDGLIITSRANNWDVILPYLAYGPIIACEYVESKEVSCSYIDRVK
AYRAGFQFLEDEGYKKVAFTAGRASRESTSTYGKINAYEQVFGSVGDNRFLSECYTLEDGLKAGEHFFAEGKDWPDAIYA
NGDEVAAGVMYHVKKLGLRVPEDVAILGQENLPIGKVLEITTLDHNLKKLGENAFTIFEQGKLQRIKVEHELIRRKTV
>Mature_317_residues
PNIKEIAKLAGVSVTTVSRVLNNHPYVAEEKRARVQAVIDELDYSPNRSAMDLARGKTNTVGVIIPYNDHPWFDKIVNGI
LEVAFKNRYSVTLFPTGYDPKEEEKYLMRLKTKQVDGLIITSRANNWDVILPYLAYGPIIACEYVESKEVSCSYIDRVKA
YRAGFQFLEDEGYKKVAFTAGRASRESTSTYGKINAYEQVFGSVGDNRFLSECYTLEDGLKAGEHFFAEGKDWPDAIYAN
GDEVAAGVMYHVKKLGLRVPEDVAILGQENLPIGKVLEITTLDHNLKKLGENAFTIFEQGKLQRIKVEHELIRRKTV

Specific function: Transcriptional regulator involved in catabolite repression of several operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=334, Percent_Identity=27.2455089820359, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790369, Length=304, Percent_Identity=25.9868421052632, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI48994940, Length=287, Percent_Identity=28.2229965156794, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790194, Length=329, Percent_Identity=26.1398176291793, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788474, Length=336, Percent_Identity=25.297619047619, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1790715, Length=280, Percent_Identity=23.5714285714286, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789202, Length=284, Percent_Identity=24.2957746478873, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787580, Length=290, Percent_Identity=25.1724137931034, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789068, Length=284, Percent_Identity=25.3521126760563, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786540, Length=329, Percent_Identity=24.9240121580547, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790689, Length=178, Percent_Identity=26.9662921348315, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787906, Length=263, Percent_Identity=24.7148288973384, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786268, Length=123, Percent_Identity=31.7073170731707, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35871; Mature: 35740

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNIKEIAKLAGVSVTTVSRVLNNHPYVAEEKRARVQAVIDELDYSPNRSAMDLARGKTN
CCCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCC
TVGVIIPYNDHPWFDKIVNGILEVAFKNRYSVTLFPTGYDPKEEEKYLMRLKTKQVDGLI
EEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEE
ITSRANNWDVILPYLAYGPIIACEYVESKEVSCSYIDRVKAYRAGFQFLEDEGYKKVAFT
EEECCCCCCEEEHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEE
AGRASRESTSTYGKINAYEQVFGSVGDNRFLSECYTLEDGLKAGEHFFAEGKDWPDAIYA
CCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCHHHHCCCCCCCCCEEC
NGDEVAAGVMYHVKKLGLRVPEDVAILGQENLPIGKVLEITTLDHNLKKLGENAFTIFEQ
CCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEECCHHHHHHCCCCEEEECC
GKLQRIKVEHELIRRKTV
CCEEEEHHHHHHHHHCCC
>Mature Secondary Structure 
PNIKEIAKLAGVSVTTVSRVLNNHPYVAEEKRARVQAVIDELDYSPNRSAMDLARGKTN
CCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCC
TVGVIIPYNDHPWFDKIVNGILEVAFKNRYSVTLFPTGYDPKEEEKYLMRLKTKQVDGLI
EEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEE
ITSRANNWDVILPYLAYGPIIACEYVESKEVSCSYIDRVKAYRAGFQFLEDEGYKKVAFT
EEECCCCCCEEEHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEE
AGRASRESTSTYGKINAYEQVFGSVGDNRFLSECYTLEDGLKAGEHFFAEGKDWPDAIYA
CCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCHHHHCCCCCCCCCEEC
NGDEVAAGVMYHVKKLGLRVPEDVAILGQENLPIGKVLEITTLDHNLKKLGENAFTIFEQ
CCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEECCHHHHHHCCCCEEEECC
GKLQRIKVEHELIRRKTV
CCEEEEHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 8011666; 9457849 [H]