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The map label for this gene is manX [H]

Identifier: 226224600

GI number: 226224600

Start: 2063667

End: 2064134

Strand: Reverse

Name: manX [H]

Synonym: Lm4b_02014

Alternate gene names: 226224600

Gene position: 2064134-2063667 (Counterclockwise)

Preceding gene: 226224601

Following gene: 226224599

Centisome position: 70.87

GC content: 38.03

Gene sequence:

>468_bases
ATGATTCAATTTCTAAGAGTGGACCATCGTTTACTACATGGACAAGTAGCTGTGTCTTGGTTTAATGCTTTAGATGTAAA
TACAATTTTAGTGGCAAATGATGGGGTAGCGGCGGACGATTTCCGTAAGTCGGCAATACGTCTTGCTAAACCCGAGGCGG
CAAAACTAGTCATGAAAAGTATCGATGAAAGTATCGAAGCGATTAATTCCGGCGTCACTGACAAATACAACATGCTTATT
GTTGTCGAATCAGTTGAAGACGCTTACAAATTAATCCATGGTACGAATGGTAAAATCCCGATGTTAAATCTAGGCGGAAC
AAAGCAACGAGAAGGAACAGCTAATTTTTCCAAAGCAATCAATTTAACACCTGAAGAAGTAGCGAAGTTAAAAGAACTTC
AAAAAGAAAATGTAGATGTATTTATGCAACAAGTGCCTAACGAGAAAAAAGTAACCTTTGAAGCATAA

Upstream 100 bases:

>100_bases
GCAGAAAACGAGATGCCAATTGCCATCCAATATCATTATGAAGATGCTGAGTCGACCAAATATGTAGTTGATTTTAACTA
ATACGAAGGAGGAAGAAAAA

Downstream 100 bases:

>100_bases
AAGACGAAAGAAGGGATAAATTATGGAACAGTTTGGAACAGCGATTTTGCTTGCACTTGCAGCAATGCTTGCAAATGGAG
AATATTTATTTGGTTCATCG

Product: PTS mannose-specific enzyme IIB component

Products: NA

Alternate protein names: EIIAB-Man; Mannose-specific phosphotransferase enzyme IIA component; EIII-Man; PTS system mannose-specific EIIA component; Mannose-specific phosphotransferase enzyme IIB component; PTS system mannose-specific EIIB component [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MIQFLRVDHRLLHGQVAVSWFNALDVNTILVANDGVAADDFRKSAIRLAKPEAAKLVMKSIDESIEAINSGVTDKYNMLI
VVESVEDAYKLIHGTNGKIPMLNLGGTKQREGTANFSKAINLTPEEVAKLKELQKENVDVFMQQVPNEKKVTFEA

Sequences:

>Translated_155_residues
MIQFLRVDHRLLHGQVAVSWFNALDVNTILVANDGVAADDFRKSAIRLAKPEAAKLVMKSIDESIEAINSGVTDKYNMLI
VVESVEDAYKLIHGTNGKIPMLNLGGTKQREGTANFSKAINLTPEEVAKLKELQKENVDVFMQQVPNEKKVTFEA
>Mature_155_residues
MIQFLRVDHRLLHGQVAVSWFNALDVNTILVANDGVAADDFRKSAIRLAKPEAAKLVMKSIDESIEAINSGVTDKYNMLI
VVESVEDAYKLIHGTNGKIPMLNLGGTKQREGTANFSKAINLTPEEVAKLKELQKENVDVFMQQVPNEKKVTFEA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG3444

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI87082217, Length=148, Percent_Identity=28.3783783783784, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1788120, Length=151, Percent_Identity=25.8278145695364, Blast_Score=67, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004701
- InterPro:   IPR004720 [H]

Pfam domain/function: PF03610 EIIA-man; PF03830 PTSIIB_sorb [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 17196; Mature: 17196

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS51101 PTS_EIIB_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQFLRVDHRLLHGQVAVSWFNALDVNTILVANDGVAADDFRKSAIRLAKPEAAKLVMKS
CCEEHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHH
IDESIEAINSGVTDKYNMLIVVESVEDAYKLIHGTNGKIPMLNLGGTKQREGTANFSKAI
HHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHCC
NLTPEEVAKLKELQKENVDVFMQQVPNEKKVTFEA
CCCHHHHHHHHHHHHCCHHHHHHHCCCCCCEEECC
>Mature Secondary Structure
MIQFLRVDHRLLHGQVAVSWFNALDVNTILVANDGVAADDFRKSAIRLAKPEAAKLVMKS
CCEEHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHH
IDESIEAINSGVTDKYNMLIVVESVEDAYKLIHGTNGKIPMLNLGGTKQREGTANFSKAI
HHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHCC
NLTPEEVAKLKELQKENVDVFMQQVPNEKKVTFEA
CCCHHHHHHHHHHHHCCHHHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA