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The map label for this gene is panC

Identifier: 226224505

GI number: 226224505

Start: 1963311

End: 1964168

Strand: Reverse

Name: panC

Synonym: Lm4b_01918

Alternate gene names: 226224505

Gene position: 1964168-1963311 (Counterclockwise)

Preceding gene: 226224506

Following gene: 226224504

Centisome position: 67.43

GC content: 38.81

Gene sequence:

>858_bases
ATGTTAATTATTCGAAATAAACAAGACCTTAAAGAAGCTATTTTAGAGCAAAAAAAAGCGAATAAAACAATTGGTTACGT
TCCGACGATGGGCTTTTTACATGAAGGACATATGACACTTGTCAGCCATGCGAGAAAAGAAACAGATTTTGTCGTTATGA
GTGTTTTTGTTAATCCAACCCAGTTCGGTCCGAACGAAGACTTTGATGCTTATCCTCGAGATGAAGCGCACGATGCAAAG
CTCGCAGAAGAAGGCGGCGTGGATATTTTATTTGTACCTACAGTCGAAGAAATCTATCCAACCGAACTAGCAACCAAACT
ACATGTCATCAAACGAGCTTCTGTACTTGATGGTGCTGATCGTGAAGGTCATTTTGACGGAGTAGTAACGGTTTTAACGA
AGCTATTTCATTTAGTGAACCCAGATAACGCCTATTTCGGTCAAAAAGATGCTCAACAAGTGGCCGTTGTTTCAGGTCTA
GTAGAAGACTACTTTTTCCCTATAAATTTACGAATCATTGCGACTGTTAGAGAAGCAGATGGACTTGCCAAAAGTTCACG
AAATGTCTATTTAACAGAAAAAGAACGAAAAGAAGCACCGGTGATTCATGAAGCTTTACAACTAGGGCGAGAACTTATTG
AATCTGGGGAAACAAATGAGGCTAAAATAGTCCAAGTCATGACAGATAAAATAAATGAGCAACCATCCCATGAGAACATT
GCTTACTTAGCGCTCTATTCCTATCCTGAATTTACACCAGTAACAGACTGGACCAAAGGAATAATCATTGCAGCGGCAGT
AAAATATTCGAAAGCTCGTTTAATTGATAATGAATTAATAAATGTGAAGAGGCGGTAA

Upstream 100 bases:

>100_bases
CTACGTAAAAGAAGTAAAAGCAGCGACGTTTCCAGAAGTGAAACATAGCTTTACCATGGCTGAAGAAGACTTAAAAGGCC
TTTATGGAAGGGAATAGCAA

Downstream 100 bases:

>100_bases
AAAATGTTTAGAACAATGATGAATGGCAAAATTCACCGAGCGACTGTAACAGAAGCCAATCTAAATTATGTTGGAAGTAT
TACGATTGATTCTGCTATTT

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MLIIRNKQDLKEAILEQKKANKTIGYVPTMGFLHEGHMTLVSHARKETDFVVMSVFVNPTQFGPNEDFDAYPRDEAHDAK
LAEEGGVDILFVPTVEEIYPTELATKLHVIKRASVLDGADREGHFDGVVTVLTKLFHLVNPDNAYFGQKDAQQVAVVSGL
VEDYFFPINLRIIATVREADGLAKSSRNVYLTEKERKEAPVIHEALQLGRELIESGETNEAKIVQVMTDKINEQPSHENI
AYLALYSYPEFTPVTDWTKGIIIAAAVKYSKARLIDNELINVKRR

Sequences:

>Translated_285_residues
MLIIRNKQDLKEAILEQKKANKTIGYVPTMGFLHEGHMTLVSHARKETDFVVMSVFVNPTQFGPNEDFDAYPRDEAHDAK
LAEEGGVDILFVPTVEEIYPTELATKLHVIKRASVLDGADREGHFDGVVTVLTKLFHLVNPDNAYFGQKDAQQVAVVSGL
VEDYFFPINLRIIATVREADGLAKSSRNVYLTEKERKEAPVIHEALQLGRELIESGETNEAKIVQVMTDKINEQPSHENI
AYLALYSYPEFTPVTDWTKGIIIAAAVKYSKARLIDNELINVKRR
>Mature_285_residues
MLIIRNKQDLKEAILEQKKANKTIGYVPTMGFLHEGHMTLVSHARKETDFVVMSVFVNPTQFGPNEDFDAYPRDEAHDAK
LAEEGGVDILFVPTVEEIYPTELATKLHVIKRASVLDGADREGHFDGVVTVLTKLFHLVNPDNAYFGQKDAQQVAVVSGL
VEDYFFPINLRIIATVREADGLAKSSRNVYLTEKERKEAPVIHEALQLGRELIESGETNEAKIVQVMTDKINEQPSHENI
AYLALYSYPEFTPVTDWTKGIIIAAAVKYSKARLIDNELINVKRR

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=284, Percent_Identity=38.7323943661972, Blast_Score=196, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6322046, Length=292, Percent_Identity=35.958904109589, Blast_Score=169, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 32080; Mature: 32080

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIIRNKQDLKEAILEQKKANKTIGYVPTMGFLHEGHMTLVSHARKETDFVVMSVFVNPT
CEEECCHHHHHHHHHHHHHCCCEEEECCCHHHHCCCCHHHHHHHCCCCCEEEEEEEECCC
QFGPNEDFDAYPRDEAHDAKLAEEGGVDILFVPTVEEIYPTELATKLHVIKRASVLDGAD
CCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCC
REGHFDGVVTVLTKLFHLVNPDNAYFGQKDAQQVAVVSGLVEDYFFPINLRIIATVREAD
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEEEEEEEHHHC
GLAKSSRNVYLTEKERKEAPVIHEALQLGRELIESGETNEAKIVQVMTDKINEQPSHENI
CHHHCCCCEEEECHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCE
AYLALYSYPEFTPVTDWTKGIIIAAAVKYSKARLIDNELINVKRR
EEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLIIRNKQDLKEAILEQKKANKTIGYVPTMGFLHEGHMTLVSHARKETDFVVMSVFVNPT
CEEECCHHHHHHHHHHHHHCCCEEEECCCHHHHCCCCHHHHHHHCCCCCEEEEEEEECCC
QFGPNEDFDAYPRDEAHDAKLAEEGGVDILFVPTVEEIYPTELATKLHVIKRASVLDGAD
CCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCC
REGHFDGVVTVLTKLFHLVNPDNAYFGQKDAQQVAVVSGLVEDYFFPINLRIIATVREAD
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEEEEEEEHHHC
GLAKSSRNVYLTEKERKEAPVIHEALQLGRELIESGETNEAKIVQVMTDKINEQPSHENI
CHHHCCCCEEEECHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCE
AYLALYSYPEFTPVTDWTKGIIIAAAVKYSKARLIDNELINVKRR
EEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]