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The map label for this gene is cbiA

Identifier: 226223791

GI number: 226223791

Start: 1197501

End: 1198859

Strand: Direct

Name: cbiA

Synonym: Lm4b_01195

Alternate gene names: 226223791

Gene position: 1197501-1198859 (Clockwise)

Preceding gene: 226223790

Following gene: 226223792

Centisome position: 41.11

GC content: 41.94

Gene sequence:

>1359_bases
ATGAACAAAATCTTAATTGCAGCTGCATCAAGTGGTACAGGTAAAACAACGATCACACTTGGAATTATGCACGCGCTAAA
AAAAAGAGGTCTGCGGGTTCAACCATTTAAAGTAGGTCCAGATTATATTGATACAAATTATCATCAAGCGATAACAGGCG
TTGCTTCTATCAATTTAGACAGTTTTCTGATAGATGATGATGCGATGCTAGCTACTCTTTTTCAAAAGCACGGAGAGTCG
GCGGATATTTCCGTCATTGAAGGTGTAATGGGTCTTTTTGATGGACTTGGTATTGATCGTGATAATTCGAGTACATCTTT
TATTGCTAAATGCACGAAAACGCCTGTAATTTTAGTCGTGGATGGTAAAGCGATATCCACTTCTGCGGCGGCAATTGTGG
ATGGATTTAATCGTTTTGATCCGGAATTAACCATTGCTGGGGTGATTATTAATCGCGTTGCTTCAGAAAACCATTTTTCA
TTGATAAAAGGGGCGATTGAACGCTATACGGATGTACCTGTTTTAGGGTATTTGCCGAAAAATGCGGCGGTGGCACTTCC
AGAACGTCATCTCGGATTAGTGCCAAAAGAGGAAATGACGGAATTAGAAACGAAATGGGAGTTACTTGGTGATTTGATTG
CGGAACATGTTGATTTAGATAGGTTGTTAGCACTTAGTAAGACTGGTGCGAAATTGACCGTACACCCACCAGAAATACAA
GTACCGGACTTTTCGGGAGTGCGCGTTGCTTATGCCCTCGACGCCGCATTTCATTTTTACTATCAAGATAACTTGGATTT
TATTCGCTCAACTGGAGCCACACTGATTCCGTTTAGTCCGCTAGAAGAAAGGGAAGTTCCGGACGCTGATTTTATTTATA
TCGGTGGTGGATTTCCGGAGGTTTTTGCGGAACGGCTAGCGAAGAACAAGTCAATGCGCGAATCGATTTTGGCGGCGCAT
GAACAAGGCAAGCCAATATATGCCGAGTGTGGCGGATTGATGTATCTTGGTTCGAGTTTAGAAATGGAAGCTGAATCCTA
TGAAATGGTAGGGGTTTTTGATGGAGTTAGTAAGATGACAACGCGGCTTCGGAAGTTTGGCTACTGTATCGCCGAACCTT
TAGAAGACACACTACTTGGTAAAAAAGGGACAGCTATTCGCGGTCATGAATTTCATCATTCTGTTTTTGAAACGACCGAA
CCAACACGTATGAAATTAACGAAAAAGCGGGATGGCAAAATTGTCAAAGAATGGCACGGCGGTTATCAAAAAGGTAATAC
GTTCGCTAGTTACCTGCATATCCATTTCTATCAAAATCTATTGATAATAACGCATATGTTTGGAGCGATAGAGCGATGA

Upstream 100 bases:

>100_bases
TTTGTGCTACAAGGAAATAGCTTATTTGCGTAAATCTCAAAAAGACGCCAATGTTCTGTTTGGCGTCTTTTTTTATGGCT
AAAGTGAAAGGTGAAAAAAG

Downstream 100 bases:

>100_bases
TATTGTTATTTTATACGTCATCATTCATTTTAGATTGCTTATTAGGTGATCCATATAGCTGGCCGCATCCTATTAAAGCG
ATCGGCAACTTGATTAAGTG

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MNKILIAAASSGTGKTTITLGIMHALKKRGLRVQPFKVGPDYIDTNYHQAITGVASINLDSFLIDDDAMLATLFQKHGES
ADISVIEGVMGLFDGLGIDRDNSSTSFIAKCTKTPVILVVDGKAISTSAAAIVDGFNRFDPELTIAGVIINRVASENHFS
LIKGAIERYTDVPVLGYLPKNAAVALPERHLGLVPKEEMTELETKWELLGDLIAEHVDLDRLLALSKTGAKLTVHPPEIQ
VPDFSGVRVAYALDAAFHFYYQDNLDFIRSTGATLIPFSPLEEREVPDADFIYIGGGFPEVFAERLAKNKSMRESILAAH
EQGKPIYAECGGLMYLGSSLEMEAESYEMVGVFDGVSKMTTRLRKFGYCIAEPLEDTLLGKKGTAIRGHEFHHSVFETTE
PTRMKLTKKRDGKIVKEWHGGYQKGNTFASYLHIHFYQNLLIITHMFGAIER

Sequences:

>Translated_452_residues
MNKILIAAASSGTGKTTITLGIMHALKKRGLRVQPFKVGPDYIDTNYHQAITGVASINLDSFLIDDDAMLATLFQKHGES
ADISVIEGVMGLFDGLGIDRDNSSTSFIAKCTKTPVILVVDGKAISTSAAAIVDGFNRFDPELTIAGVIINRVASENHFS
LIKGAIERYTDVPVLGYLPKNAAVALPERHLGLVPKEEMTELETKWELLGDLIAEHVDLDRLLALSKTGAKLTVHPPEIQ
VPDFSGVRVAYALDAAFHFYYQDNLDFIRSTGATLIPFSPLEEREVPDADFIYIGGGFPEVFAERLAKNKSMRESILAAH
EQGKPIYAECGGLMYLGSSLEMEAESYEMVGVFDGVSKMTTRLRKFGYCIAEPLEDTLLGKKGTAIRGHEFHHSVFETTE
PTRMKLTKKRDGKIVKEWHGGYQKGNTFASYLHIHFYQNLLIITHMFGAIER
>Mature_452_residues
MNKILIAAASSGTGKTTITLGIMHALKKRGLRVQPFKVGPDYIDTNYHQAITGVASINLDSFLIDDDAMLATLFQKHGES
ADISVIEGVMGLFDGLGIDRDNSSTSFIAKCTKTPVILVVDGKAISTSAAAIVDGFNRFDPELTIAGVIINRVASENHFS
LIKGAIERYTDVPVLGYLPKNAAVALPERHLGLVPKEEMTELETKWELLGDLIAEHVDLDRLLALSKTGAKLTVHPPEIQ
VPDFSGVRVAYALDAAFHFYYQDNLDFIRSTGATLIPFSPLEEREVPDADFIYIGGGFPEVFAERLAKNKSMRESILAAH
EQGKPIYAECGGLMYLGSSLEMEAESYEMVGVFDGVSKMTTRLRKFGYCIAEPLEDTLLGKKGTAIRGHEFHHSVFETTE
PTRMKLTKKRDGKIVKEWHGGYQKGNTFASYLHIHFYQNLLIITHMFGAIER

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 49847; Mature: 49847

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKILIAAASSGTGKTTITLGIMHALKKRGLRVQPFKVGPDYIDTNYHQAITGVASINLD
CCEEEEEEECCCCCCEEEHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHEEECCC
SFLIDDDAMLATLFQKHGESADISVIEGVMGLFDGLGIDRDNSSTSFIAKCTKTPVILVV
CEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEEE
DGKAISTSAAAIVDGFNRFDPELTIAGVIINRVASENHFSLIKGAIERYTDVPVLGYLPK
CCCCCCCHHHHHHHCHHHCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCC
NAAVALPERHLGLVPKEEMTELETKWELLGDLIAEHVDLDRLLALSKTGAKLTVHPPEIQ
CCEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCCEE
VPDFSGVRVAYALDAAFHFYYQDNLDFIRSTGATLIPFSPLEEREVPDADFIYIGGGFPE
CCCCCCCEEEEEEEHEEEEEEECCCHHHHCCCCEEEECCCCCCCCCCCCCEEEECCCCHH
VFAERLAKNKSMRESILAAHEQGKPIYAECGGLMYLGSSLEMEAESYEMVGVFDGVSKMT
HHHHHHHCCHHHHHHHHHHHHCCCEEEECCCCEEEECCCCEECCCCEEEEEECCCHHHHH
TRLRKFGYCIAEPLEDTLLGKKGTAIRGHEFHHSVFETTEPTRMKLTKKRDGKIVKEWHG
HHHHHHCCHHHCCHHHHHCCCCCCEECCCHHHHHHHCCCCCHHEEEECCCCCCCHHHHCC
GYQKGNTFASYLHIHFYQNLLIITHMFGAIER
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKILIAAASSGTGKTTITLGIMHALKKRGLRVQPFKVGPDYIDTNYHQAITGVASINLD
CCEEEEEEECCCCCCEEEHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHEEECCC
SFLIDDDAMLATLFQKHGESADISVIEGVMGLFDGLGIDRDNSSTSFIAKCTKTPVILVV
CEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEEE
DGKAISTSAAAIVDGFNRFDPELTIAGVIINRVASENHFSLIKGAIERYTDVPVLGYLPK
CCCCCCCHHHHHHHCHHHCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCC
NAAVALPERHLGLVPKEEMTELETKWELLGDLIAEHVDLDRLLALSKTGAKLTVHPPEIQ
CCEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCCEE
VPDFSGVRVAYALDAAFHFYYQDNLDFIRSTGATLIPFSPLEEREVPDADFIYIGGGFPE
CCCCCCCEEEEEEEHEEEEEEECCCHHHHCCCCEEEECCCCCCCCCCCCCEEEECCCCHH
VFAERLAKNKSMRESILAAHEQGKPIYAECGGLMYLGSSLEMEAESYEMVGVFDGVSKMT
HHHHHHHCCHHHHHHHHHHHHCCCEEEECCCCEEEECCCCEECCCCEEEEEECCCHHHHH
TRLRKFGYCIAEPLEDTLLGKKGTAIRGHEFHHSVFETTEPTRMKLTKKRDGKIVKEWHG
HHHHHHCCHHHCCHHHHHCCCCCCEECCCHHHHHHHCCCCCHHEEEECCCCCCCHHHHCC
GYQKGNTFASYLHIHFYQNLLIITHMFGAIER
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA