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The map label for this gene is tagO [H]

Identifier: 226223577

GI number: 226223577

Start: 992863

End: 993918

Strand: Direct

Name: tagO [H]

Synonym: Lm4b_00979

Alternate gene names: 226223577

Gene position: 992863-993918 (Clockwise)

Preceding gene: 226223576

Following gene: 226223578

Centisome position: 34.09

GC content: 36.36

Gene sequence:

>1056_bases
ATGAGCTGGATGATTATATTGATATGTTTTGGCGCGTCCGTATTACTTACACCGCTAATTCGAAAAATAGCTCTATACTT
TGATATTACAGATAAACCAGACCAACGTCGTATTAATATTAAACCAATTCCGAGTTTAGGTGGACTAGCAATGTTTATCA
GTTTTACTATCGGAATGTTTTTACTCCCAATTGAAAACGAATTCTTATGGCCGCTTCTGATTGCAGCATTTGTCATGGTT
TTGACTGGGCTATTAGATGATATTATGGAATTTAAAGCAAGATATAAATTAATCGGCCAAGTTACCGCTGCCTTTATTAT
TGTGTTTTGGGGTAACATTAGTATCGACTTTATCAACTTACCATTCGGTGGGGAAATCCATTTTGGGGTGTTAAGTATCC
CACTCACAATTATTTGGATTGTAGCCATTACGAATGCTATAAATCTAATTGATGGACTGGACGGTCTTGCCGCAGGTGTT
TCAACCATTGCCTTACTCACTATTTTAGGAATGGCGTTTATTATGGGAGATGCACTAGTAATTATGATAGCAAGTGTGTT
AATCGCTGGGACACTTGGTTTCTTACCTTATAATTTTAATCCTGCAAAAATTTTCATGGGTGACACTGGCGCGCTTTTCT
TAGGTTTTATTATTTCCGTGTTATCCGTGATGGGATTCAAAAATGTTACGTTTATCTCTTTAATCGTACCAATTTTAATT
TTAGGTGTACCGATTTCTGATACACTTTTTGCTATTATACGACGCATGGTAACGAAACAACCAATCGCGATGGCAGATAA
GTCGCATTTACATCATTGTTTATTACGACTAGGCTTCACGCATCGTCAAACGGTTATTTTGATTTATGCCATTGCCGCAC
TATTTTCTTTATTTGCCTTCATTTTCACGATGTCGACACTGTGGGGTTCGATGATTTTAATCGGTGTACTACTCATTTTA
ATTGAGGTATTGATTGAGACGCTTGGATTAGTAGGGAGCACATATCGCCCATTACTTAATTTATTTAAATTAACCAAAGA
AGAAAAAATAGATTAG

Upstream 100 bases:

>100_bases
TCTGTCTGCCCCAAGCTTTTTTGCATAATGATTTTCGTTGTCTTTTTGCAAATAAAAAAGTATAATGAGATGAGTAAAAA
ATTTGCGGGGAGGACTAGCC

Downstream 100 bases:

>100_bases
AGATTGGTCACTTAGACTAGTCTCTTTTTTTATGCCAAAATTCTTATTGAGTAACAAGTCTTCTTGTGATACATTTATCA
AGTAACGTTTTTGTAGAAAT

Product: undacaprenyl-phosphate N-acetylglucosaminyltransferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSWMIILICFGASVLLTPLIRKIALYFDITDKPDQRRINIKPIPSLGGLAMFISFTIGMFLLPIENEFLWPLLIAAFVMV
LTGLLDDIMEFKARYKLIGQVTAAFIIVFWGNISIDFINLPFGGEIHFGVLSIPLTIIWIVAITNAINLIDGLDGLAAGV
STIALLTILGMAFIMGDALVIMIASVLIAGTLGFLPYNFNPAKIFMGDTGALFLGFIISVLSVMGFKNVTFISLIVPILI
LGVPISDTLFAIIRRMVTKQPIAMADKSHLHHCLLRLGFTHRQTVILIYAIAALFSLFAFIFTMSTLWGSMILIGVLLIL
IEVLIETLGLVGSTYRPLLNLFKLTKEEKID

Sequences:

>Translated_351_residues
MSWMIILICFGASVLLTPLIRKIALYFDITDKPDQRRINIKPIPSLGGLAMFISFTIGMFLLPIENEFLWPLLIAAFVMV
LTGLLDDIMEFKARYKLIGQVTAAFIIVFWGNISIDFINLPFGGEIHFGVLSIPLTIIWIVAITNAINLIDGLDGLAAGV
STIALLTILGMAFIMGDALVIMIASVLIAGTLGFLPYNFNPAKIFMGDTGALFLGFIISVLSVMGFKNVTFISLIVPILI
LGVPISDTLFAIIRRMVTKQPIAMADKSHLHHCLLRLGFTHRQTVILIYAIAALFSLFAFIFTMSTLWGSMILIGVLLIL
IEVLIETLGLVGSTYRPLLNLFKLTKEEKID
>Mature_350_residues
SWMIILICFGASVLLTPLIRKIALYFDITDKPDQRRINIKPIPSLGGLAMFISFTIGMFLLPIENEFLWPLLIAAFVMVL
TGLLDDIMEFKARYKLIGQVTAAFIIVFWGNISIDFINLPFGGEIHFGVLSIPLTIIWIVAITNAINLIDGLDGLAAGVS
TIALLTILGMAFIMGDALVIMIASVLIAGTLGFLPYNFNPAKIFMGDTGALFLGFIISVLSVMGFKNVTFISLIVPILIL
GVPISDTLFAIIRRMVTKQPIAMADKSHLHHCLLRLGFTHRQTVILIYAIAALFSLFAFIFTMSTLWGSMILIGVLLILI
EVLIETLGLVGSTYRPLLNLFKLTKEEKID

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=276, Percent_Identity=28.6231884057971, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 38655; Mature: 38524

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWMIILICFGASVLLTPLIRKIALYFDITDKPDQRRINIKPIPSLGGLAMFISFTIGMF
CCCEEEEHHHCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHH
LLPIENEFLWPLLIAAFVMVLTGLLDDIMEFKARYKLIGQVTAAFIIVFWGNISIDFINL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEC
PFGGEIHFGVLSIPLTIIWIVAITNAINLIDGLDGLAAGVSTIALLTILGMAFIMGDALV
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMIASVLIAGTLGFLPYNFNPAKIFMGDTGALFLGFIISVLSVMGFKNVTFISLIVPILI
HHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LGVPISDTLFAIIRRMVTKQPIAMADKSHLHHCLLRLGFTHRQTVILIYAIAALFSLFAF
HCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IFTMSTLWGSMILIGVLLILIEVLIETLGLVGSTYRPLLNLFKLTKEEKID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SWMIILICFGASVLLTPLIRKIALYFDITDKPDQRRINIKPIPSLGGLAMFISFTIGMF
CCEEEEHHHCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHH
LLPIENEFLWPLLIAAFVMVLTGLLDDIMEFKARYKLIGQVTAAFIIVFWGNISIDFINL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEC
PFGGEIHFGVLSIPLTIIWIVAITNAINLIDGLDGLAAGVSTIALLTILGMAFIMGDALV
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMIASVLIAGTLGFLPYNFNPAKIFMGDTGALFLGFIISVLSVMGFKNVTFISLIVPILI
HHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LGVPISDTLFAIIRRMVTKQPIAMADKSHLHHCLLRLGFTHRQTVILIYAIAALFSLFAF
HCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IFTMSTLWGSMILIGVLLILIEVLIETLGLVGSTYRPLLNLFKLTKEEKID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]