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The map label for this gene is 226223547

Identifier: 226223547

GI number: 226223547

Start: 966637

End: 967260

Strand: Direct

Name: 226223547

Synonym: Lm4b_00947

Alternate gene names: NA

Gene position: 966637-967260 (Clockwise)

Preceding gene: 226223545

Following gene: 226223548

Centisome position: 33.19

GC content: 39.9

Gene sequence:

>624_bases
ATGGAAGCGATTATTACGAAAGAATTTTTTGAAGATAAGACAACAATCGAATTAGCGAGAGATATCTTGGGTATGCGTCT
AGTACATCAAACGGATGAGGGAATTCTATCTGGGCTAATAGTGGAAACAGAAGCGTACCTCGGGGCAACAGATATGGCTG
CACATAGTTTTCAAAACCTCCGAACGAAACGAACAGAAGTCATGTTTTCATCGCCGGGAAGAATCTACATGTACCAAATG
CATCGCCAAGTGTTGCTTAATTTTATAACCATGCCAAAAGGAATCCCAGAAGCCATTCTAATACGAGCCATCGAACCTGA
CGAACAAGCTAAACAACAAATGGTACAAAATCGTCACGGAAAAACTGGTTACGAACTTACCAATGGCCCCGGAAAATTAA
CGCAAGCTTTAGGATTAAGTATGCAAGATTACGGGAAAACTCTTTTTGATAGTAACATTTGGTTAGAAGAGGCAAAATTG
CCGCATTTAATAGAAGCAACTAATCGAATAGGGGTGCCAAACAAAGGAATTGCAACTCATTTTCCACTCAGATTTACTGT
TAAAGGCAGCCCATATATTTCAGCTCAACGAAAAAGTCGGATTCTTACCGATATTTGGAAGTGA

Upstream 100 bases:

>100_bases
GAAGTAGGATTTTAGGGGAAATAGGCTGATATAACTAGTCAAAAAAGAACCATTTGGAATAGAATTCTGCTAGAATAAAA
AGAAAACATTGAGGTATGAA

Downstream 100 bases:

>100_bases
CTTTACAATTTTGTCACAGGTAGAGAAAATAGTTTTATCCAGACACTGATTTTCTTTGCTTCATAAGAAGAGCTACTATA
TAATGAAATAGTTACAAGGA

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MEAIITKEFFEDKTTIELARDILGMRLVHQTDEGILSGLIVETEAYLGATDMAAHSFQNLRTKRTEVMFSSPGRIYMYQM
HRQVLLNFITMPKGIPEAILIRAIEPDEQAKQQMVQNRHGKTGYELTNGPGKLTQALGLSMQDYGKTLFDSNIWLEEAKL
PHLIEATNRIGVPNKGIATHFPLRFTVKGSPYISAQRKSRILTDIWK

Sequences:

>Translated_207_residues
MEAIITKEFFEDKTTIELARDILGMRLVHQTDEGILSGLIVETEAYLGATDMAAHSFQNLRTKRTEVMFSSPGRIYMYQM
HRQVLLNFITMPKGIPEAILIRAIEPDEQAKQQMVQNRHGKTGYELTNGPGKLTQALGLSMQDYGKTLFDSNIWLEEAKL
PHLIEATNRIGVPNKGIATHFPLRFTVKGSPYISAQRKSRILTDIWK
>Mature_207_residues
MEAIITKEFFEDKTTIELARDILGMRLVHQTDEGILSGLIVETEAYLGATDMAAHSFQNLRTKRTEVMFSSPGRIYMYQM
HRQVLLNFITMPKGIPEAILIRAIEPDEQAKQQMVQNRHGKTGYELTNGPGKLTQALGLSMQDYGKTLFDSNIWLEEAKL
PHLIEATNRIGVPNKGIATHFPLRFTVKGSPYISAQRKSRILTDIWK

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632765, Length=201, Percent_Identity=36.81592039801, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI62632769, Length=201, Percent_Identity=36.81592039801, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI62632771, Length=201, Percent_Identity=36.81592039801, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_LISMC (C1L1K0)

Other databases:

- EMBL:   FM242711
- RefSeq:   YP_002757654.1
- ProteinModelPortal:   C1L1K0
- SMR:   C1L1K0
- GeneID:   7704526
- GenomeReviews:   FM242711_GR
- KEGG:   lmc:Lm4b_00947
- OMA:   EHISSQY
- ProtClustDB:   PRK00802
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.-

Molecular weight: Translated: 23492; Mature: 23492

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAIITKEFFEDKTTIELARDILGMRLVHQTDEGILSGLIVETEAYLGATDMAAHSFQNL
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEHHHHCCHHHHHHHHHHHH
RTKRTEVMFSSPGRIYMYQMHRQVLLNFITMPKGIPEAILIRAIEPDEQAKQQMVQNRHG
HHHHHHEEECCCCEEEHHHHHHHHHHHHHHCCCCCCHHHEEEECCCCHHHHHHHHHHCCC
KTGYELTNGPGKLTQALGLSMQDYGKTLFDSNIWLEEAKLPHLIEATNRIGVPNKGIATH
CCCCEEECCCHHHHHHHCCCHHHHHHHHHCCCCEEECCCCCHHHHHHHCCCCCCCCCEEE
FPLRFTVKGSPYISAQRKSRILTDIWK
CCEEEEECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MEAIITKEFFEDKTTIELARDILGMRLVHQTDEGILSGLIVETEAYLGATDMAAHSFQNL
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEHHHHCCHHHHHHHHHHHH
RTKRTEVMFSSPGRIYMYQMHRQVLLNFITMPKGIPEAILIRAIEPDEQAKQQMVQNRHG
HHHHHHEEECCCCEEEHHHHHHHHHHHHHHCCCCCCHHHEEEECCCCHHHHHHHHHHCCC
KTGYELTNGPGKLTQALGLSMQDYGKTLFDSNIWLEEAKLPHLIEATNRIGVPNKGIATH
CCCCEEECCCHHHHHHHCCCHHHHHHHHHCCCCEEECCCCCHHHHHHHCCCCCCCCCEEE
FPLRFTVKGSPYISAQRKSRILTDIWK
CCEEEEECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA