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The map label for this gene is ubiE [C]

Identifier: 226223261

GI number: 226223261

Start: 674929

End: 675522

Strand: Direct

Name: ubiE [C]

Synonym: Lm4b_00658

Alternate gene names: 226223261

Gene position: 674929-675522 (Clockwise)

Preceding gene: 226223260

Following gene: 226223262

Centisome position: 23.17

GC content: 42.42

Gene sequence:

>594_bases
ATGAAACATCATCATAATCATCACGGGGAAGCTGGTTTTAAGCGGAAAGTAGATTATTTGGATCGACCAGAGCGGAGTGA
AGTGCTGTCGCCAGAGGATTTTTTGCAGGCAATGCCAATCGGAAAAACAGCAAGTATTTTAGATTTAGGAGCGGGAACAG
GATTTTTAACAATTCCAGCTGCAAAATTCGTTGATAATACAGTTTTTGCATTAGATTTAGATGCGAAAATGTTGGAATTA
ATTGAGTCAAAAGCGAAGGAAGCAGGTTTGGCTAATGTAGAAACGTTAGAAGCCAGCATGGATGATATTCCACTTGAGGC
AAATTCCGTGGATGTTGTGCTCGCATCGCTCGTGTTACATGAAGCAGATTCGCTCGCAGATGTTTTGCGCGAAGTGAGTA
GAGTTGTGAAGACTGGCGGCTACTTTGCTAGTTTGGAATTTGACACGAAAGGGACTGATTTAAAAGGCCCACCAATGGAA
ATTCAGATTTCTGCGGAGAAATTGAAGGAAGAGCTTGCGGGATTTGGGTTTGAAGTGGTGAAGAATTGGCAGTTGGATGA
GGGTATGTATGTGAGTATTGCGGTGAAGAAGTAA

Upstream 100 bases:

>100_bases
GAATAAGGCGGAGCAACAAATGGAAGATTATTTAAGCAAACAAACAGTAGGTAGTATTGTCGTAGAAATTGAAAAACATC
AACATTAAAGGAGTGCTAAA

Downstream 100 bases:

>100_bases
CAGCAAAAAGGTTCACGTCTAAAAATAGCAATCAAAGCTATTTTTAAGCGTGAACCTTTTTATTTCTACGGAGAAACGGG
GATTCGAACCCCGGCGCGGC

Product: methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Methyltransferase; SAM-Dependent Methyltransferase; Arsenite S-Adenosylmethyltransferase; UbiE/COQ5 Family Methlytransferase; Methyltransferase UbiE/COQ5 Family; Methyltransferase In Menaquinone/Biotin Biosynthesis; Ubiquinone/Menaquinone Biosynthesis Methyltransferase UbiE; S-Adenosylmethionine-Dependent Methyltransferase; Methyltransferase Domain Protein; S-Adenosyl-L-Methionine-Dependent Methyltransferase; Arsenite Methyltransferase; RRNA-Methyltransferase; Methyltransferase Domain Family Protein; UbiE/COQ5 Methyltransferase; Methylase

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKHHHNHHGEAGFKRKVDYLDRPERSEVLSPEDFLQAMPIGKTASILDLGAGTGFLTIPAAKFVDNTVFALDLDAKMLEL
IESKAKEAGLANVETLEASMDDIPLEANSVDVVLASLVLHEADSLADVLREVSRVVKTGGYFASLEFDTKGTDLKGPPME
IQISAEKLKEELAGFGFEVVKNWQLDEGMYVSIAVKK

Sequences:

>Translated_197_residues
MKHHHNHHGEAGFKRKVDYLDRPERSEVLSPEDFLQAMPIGKTASILDLGAGTGFLTIPAAKFVDNTVFALDLDAKMLEL
IESKAKEAGLANVETLEASMDDIPLEANSVDVVLASLVLHEADSLADVLREVSRVVKTGGYFASLEFDTKGTDLKGPPME
IQISAEKLKEELAGFGFEVVKNWQLDEGMYVSIAVKK
>Mature_197_residues
MKHHHNHHGEAGFKRKVDYLDRPERSEVLSPEDFLQAMPIGKTASILDLGAGTGFLTIPAAKFVDNTVFALDLDAKMLEL
IESKAKEAGLANVETLEASMDDIPLEANSVDVVLASLVLHEADSLADVLREVSRVVKTGGYFASLEFDTKGTDLKGPPME
IQISAEKLKEELAGFGFEVVKNWQLDEGMYVSIAVKK

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 21542; Mature: 21542

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHHHNHHGEAGFKRKVDYLDRPERSEVLSPEDFLQAMPIGKTASILDLGAGTGFLTIPA
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCEEEECH
AKFVDNTVFALDLDAKMLELIESKAKEAGLANVETLEASMDDIPLEANSVDVVLASLVLH
HHHHCCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHH
EADSLADVLREVSRVVKTGGYFASLEFDTKGTDLKGPPMEIQISAEKLKEELAGFGFEVV
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEEEEEHHHHHHHHHCCCHHHH
KNWQLDEGMYVSIAVKK
HCCCCCCCEEEEEEEEC
>Mature Secondary Structure
MKHHHNHHGEAGFKRKVDYLDRPERSEVLSPEDFLQAMPIGKTASILDLGAGTGFLTIPA
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCEEEECH
AKFVDNTVFALDLDAKMLELIESKAKEAGLANVETLEASMDDIPLEANSVDVVLASLVLH
HHHHCCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHH
EADSLADVLREVSRVVKTGGYFASLEFDTKGTDLKGPPMEIQISAEKLKEELAGFGFEVV
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEEEEEHHHHHHHHHCCCHHHH
KNWQLDEGMYVSIAVKK
HCCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA