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The map label for this gene is leuE [H]

Identifier: 225686041

GI number: 225686041

Start: 170296

End: 170913

Strand: Direct

Name: leuE [H]

Synonym: BMEA_B0186

Alternate gene names: 225686041

Gene position: 170296-170913 (Clockwise)

Preceding gene: 225686040

Following gene: 225686042

Centisome position: 14.36

GC content: 59.55

Gene sequence:

>618_bases
ATGGACCTGATGTCGCTTGTGGCCTTTGCTGGTATTCTGGTGGTTGCGGCGGGCACGCCCGGCCCGAATGTCGGTGCGCT
GGTCGCGCGCGTCATCAGCCGTGGGCACAAGGGCGTTTTTCCCTTCATGTTCGGCCTGTGGCTTGGCGATGCCGTCTGGC
TTTCGCTGGCGGTATGGGGGCTTTCCGCCCTTGCCCATACGTTCCAGACTGCTTTCCTGGTACTCAAATATGCAGGCGTT
GCCTATCTGATCTATCTTTCCTGGAAAATGTGGTTTGCGCCCGTGGATGAGGAAGCCGATGAAAACACCATCCCCCGCCA
GGGTGAGGGCAAGAGGCTTTTCCTGAGCGCGCTTGGCGTCACACTCGGCAATCCCAAGATCATGGTTTTCTATCTCGCGA
TCCTGCCGACAGTCGTGGATATTACCCATGTCTCGCTCACGGGCTGGGTGGAGCTGCTTCTGGTTATGTTCATGGTTCTG
GCTGCTGTCGATACGGCATGGGTGGTCCTGGCTGCGCAGGCGCGCAAGTTTTTGCGCAGCCCGCGCATGATGCGCCTTGC
CAACAGAACCAATGCCGGCATGATGGCGGGTGCTGCCGTCGCCATTGCCGCACGCTGA

Upstream 100 bases:

>100_bases
TCTGCCAGAAACGCATCTGGATGCATTCACGCACGTCTTTATTCCACAGCCGGTTCCATTTATGGGAAACGCGCTCTGGT
AAGTTCAAGGGAAGACATTC

Downstream 100 bases:

>100_bases
ACATGTTTCCCGCACTTGCCGCAACGGGCTTGATCGGTTAGGAAACCGGCAGCGAATGTGCCGGTTCCTTCCGGCGCGAC
AGGAACAAAATCAGCGATCA

Product: Lysine exporter protein LYSE/YGGA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MDLMSLVAFAGILVVAAGTPGPNVGALVARVISRGHKGVFPFMFGLWLGDAVWLSLAVWGLSALAHTFQTAFLVLKYAGV
AYLIYLSWKMWFAPVDEEADENTIPRQGEGKRLFLSALGVTLGNPKIMVFYLAILPTVVDITHVSLTGWVELLLVMFMVL
AAVDTAWVVLAAQARKFLRSPRMMRLANRTNAGMMAGAAVAIAAR

Sequences:

>Translated_205_residues
MDLMSLVAFAGILVVAAGTPGPNVGALVARVISRGHKGVFPFMFGLWLGDAVWLSLAVWGLSALAHTFQTAFLVLKYAGV
AYLIYLSWKMWFAPVDEEADENTIPRQGEGKRLFLSALGVTLGNPKIMVFYLAILPTVVDITHVSLTGWVELLLVMFMVL
AAVDTAWVVLAAQARKFLRSPRMMRLANRTNAGMMAGAAVAIAAR
>Mature_205_residues
MDLMSLVAFAGILVVAAGTPGPNVGALVARVISRGHKGVFPFMFGLWLGDAVWLSLAVWGLSALAHTFQTAFLVLKYAGV
AYLIYLSWKMWFAPVDEEADENTIPRQGEGKRLFLSALGVTLGNPKIMVFYLAILPTVVDITHVSLTGWVELLLVMFMVL
AAVDTAWVVLAAQARKFLRSPRMMRLANRTNAGMMAGAAVAIAAR

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=194, Percent_Identity=28.3505154639175, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI48994979, Length=189, Percent_Identity=29.1005291005291, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22181; Mature: 22181

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLMSLVAFAGILVVAAGTPGPNVGALVARVISRGHKGVFPFMFGLWLGDAVWLSLAVWG
CCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LSALAHTFQTAFLVLKYAGVAYLIYLSWKMWFAPVDEEADENTIPRQGEGKRLFLSALGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEHHHHHHH
TLGNPKIMVFYLAILPTVVDITHVSLTGWVELLLVMFMVLAAVDTAWVVLAAQARKFLRS
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PRMMRLANRTNAGMMAGAAVAIAAR
CHHHHHHCCCCCCHHHHHHEEEECC
>Mature Secondary Structure
MDLMSLVAFAGILVVAAGTPGPNVGALVARVISRGHKGVFPFMFGLWLGDAVWLSLAVWG
CCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LSALAHTFQTAFLVLKYAGVAYLIYLSWKMWFAPVDEEADENTIPRQGEGKRLFLSALGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEHHHHHHH
TLGNPKIMVFYLAILPTVVDITHVSLTGWVELLLVMFMVLAAVDTAWVVLAAQARKFLRS
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PRMMRLANRTNAGMMAGAAVAIAAR
CHHHHHHCCCCCCHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]