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The map label for this gene is hrcA

Identifier: 225851705

GI number: 225851705

Start: 184175

End: 185245

Strand: Reverse

Name: hrcA

Synonym: BMEA_A0178

Alternate gene names: 225851705

Gene position: 185245-184175 (Counterclockwise)

Preceding gene: 225851717

Following gene: 225851704

Centisome position: 8.71

GC content: 59.85

Gene sequence:

>1071_bases
ATGATGAGACCGCCGGAACACCAGCTCCTCAGTTCGCTCGACCAGCGCTCGCGCGATATTTTCCGGCTCATCGTCGAAAC
CTATCTCAATGACGGTGATCCGGTCGGCTCACGCAATCTCTCGCGGCTTCTGCCGCACACGCTTTCGCCCGCCACGATCC
GCAATGTGATGAGCGATCTGGAACATCTGGGCCTGATCTATGCGCCGCATATTTCCGCTGGCCGCCTGCCGACGCAGATC
GGCCTGCGCTTCTTTGTCGATGCCTTTCTGGAAGTGGGAGACCTGCCGCCGGAGGAACGCTCCTCCATCGAGGCGCAGGT
ACGCGCCGCAGGCACCAGCAATTCGGTGGAAAGCGTCCTGACCGAAGCAAGCCAGGTGCTTTCAGGCCTGTCACGCGGGG
CGGGCCTTGTGCTCACCAACAAGACCGATGTGGCGCTGAAACATATCGAATTCGTGCGCCTTGAACCCATGCGCGCCCTG
GCTGTTCTGGTCATGCAGAACGGCGATGTGGAAAACCGTGTGATTGATCTTCCGGCGGGCATCAGCACCTCGCAGCTCAT
CGAAGCCTCCAATTTTCTCAATGCCCATATTCATGGCCACACGCTTTCGGAAGCCAAATCCGAATTGAGGAAACTGAGCG
AGGAAACACGGCGGGAGCTTGACCAGCTTTCACAGGAACTGGTGGCGAAGGGACTTGCAGTATGGAGCGGCGCCGGCGCG
GACCAGCCCGCACGCCTCATCGTGCGCGGACGCGCCAATCTTCTGGAAAACGTCCACGCACAGGAAGACATAGAGCGGCT
GCGCCATCTCTTCGACGATCTCGAAACCAAGGACGGGATGGTGCAGCTTCTGGACCTGGCGGAAGCAGGCTCGGGCGTGC
GCATTTTCATCGGTTCGGAAAACAAGCTTTTCTCGCTTTCCGGCTCGTCGCTGGTGGTTGCCCCCTATCGCGACAGCGAA
CAACGGGTTATCGGTGCCCTGGGGGTGATCGGGCCGACCCGGCTCAATTATGCGCGCATCGTTCCGATGGTGGACTATAC
GGCGCAGATCGTATCGAGGCTGCTGCGATAA

Upstream 100 bases:

>100_bases
CGCCACCGGCAAAGGCGCATTCATGCTCTAAACTCTTTGACGCAACATGCCGCAGCCTTATATTTATTACATTCAATTCA
GAGGGTTCGCAGAACAAACC

Downstream 100 bases:

>100_bases
CTGTCAGATTTGCCGGTGCGCACCAGCCCCCAGAAATTAGACCTTGATTTTAAAGGCACGAAACTCGATATCCGCCCCTA
ACGATCTTCAAGACGGAAGC

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MMRPPEHQLLSSLDQRSRDIFRLIVETYLNDGDPVGSRNLSRLLPHTLSPATIRNVMSDLEHLGLIYAPHISAGRLPTQI
GLRFFVDAFLEVGDLPPEERSSIEAQVRAAGTSNSVESVLTEASQVLSGLSRGAGLVLTNKTDVALKHIEFVRLEPMRAL
AVLVMQNGDVENRVIDLPAGISTSQLIEASNFLNAHIHGHTLSEAKSELRKLSEETRRELDQLSQELVAKGLAVWSGAGA
DQPARLIVRGRANLLENVHAQEDIERLRHLFDDLETKDGMVQLLDLAEAGSGVRIFIGSENKLFSLSGSSLVVAPYRDSE
QRVIGALGVIGPTRLNYARIVPMVDYTAQIVSRLLR

Sequences:

>Translated_356_residues
MMRPPEHQLLSSLDQRSRDIFRLIVETYLNDGDPVGSRNLSRLLPHTLSPATIRNVMSDLEHLGLIYAPHISAGRLPTQI
GLRFFVDAFLEVGDLPPEERSSIEAQVRAAGTSNSVESVLTEASQVLSGLSRGAGLVLTNKTDVALKHIEFVRLEPMRAL
AVLVMQNGDVENRVIDLPAGISTSQLIEASNFLNAHIHGHTLSEAKSELRKLSEETRRELDQLSQELVAKGLAVWSGAGA
DQPARLIVRGRANLLENVHAQEDIERLRHLFDDLETKDGMVQLLDLAEAGSGVRIFIGSENKLFSLSGSSLVVAPYRDSE
QRVIGALGVIGPTRLNYARIVPMVDYTAQIVSRLLR
>Mature_356_residues
MMRPPEHQLLSSLDQRSRDIFRLIVETYLNDGDPVGSRNLSRLLPHTLSPATIRNVMSDLEHLGLIYAPHISAGRLPTQI
GLRFFVDAFLEVGDLPPEERSSIEAQVRAAGTSNSVESVLTEASQVLSGLSRGAGLVLTNKTDVALKHIEFVRLEPMRAL
AVLVMQNGDVENRVIDLPAGISTSQLIEASNFLNAHIHGHTLSEAKSELRKLSEETRRELDQLSQELVAKGLAVWSGAGA
DQPARLIVRGRANLLENVHAQEDIERLRHLFDDLETKDGMVQLLDLAEAGSGVRIFIGSENKLFSLSGSSLVVAPYRDSE
QRVIGALGVIGPTRLNYARIVPMVDYTAQIVSRLLR

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_BRUA1 (B2S8G3)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001934190.1
- GeneID:   6328107
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I01620
- HOGENOM:   HBG729878
- OMA:   LEQPHTS
- ProtClustDB:   PRK00082
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF01628 HrcA

EC number: NA

Molecular weight: Translated: 39094; Mature: 39094

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRPPEHQLLSSLDQRSRDIFRLIVETYLNDGDPVGSRNLSRLLPHTLSPATIRNVMSDL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHH
EHLGLIYAPHISAGRLPTQIGLRFFVDAFLEVGDLPPEERSSIEAQVRAAGTSNSVESVL
HHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHH
TEASQVLSGLSRGAGLVLTNKTDVALKHIEFVRLEPMRALAVLVMQNGDVENRVIDLPAG
HHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEECCCC
ISTSQLIEASNFLNAHIHGHTLSEAKSELRKLSEETRRELDQLSQELVAKGLAVWSGAGA
CCHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DQPARLIVRGRANLLENVHAQEDIERLRHLFDDLETKDGMVQLLDLAEAGSGVRIFIGSE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCC
NKLFSLSGSSLVVAPYRDSEQRVIGALGVIGPTRLNYARIVPMVDYTAQIVSRLLR
CCEEEECCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MMRPPEHQLLSSLDQRSRDIFRLIVETYLNDGDPVGSRNLSRLLPHTLSPATIRNVMSDL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHH
EHLGLIYAPHISAGRLPTQIGLRFFVDAFLEVGDLPPEERSSIEAQVRAAGTSNSVESVL
HHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHH
TEASQVLSGLSRGAGLVLTNKTDVALKHIEFVRLEPMRALAVLVMQNGDVENRVIDLPAG
HHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEECCCC
ISTSQLIEASNFLNAHIHGHTLSEAKSELRKLSEETRRELDQLSQELVAKGLAVWSGAGA
CCHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DQPARLIVRGRANLLENVHAQEDIERLRHLFDDLETKDGMVQLLDLAEAGSGVRIFIGSE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCC
NKLFSLSGSSLVVAPYRDSEQRVIGALGVIGPTRLNYARIVPMVDYTAQIVSRLLR
CCEEEECCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA