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The map label for this gene is frr

Identifier: 222527070

GI number: 222527070

Start: 4794501

End: 4795058

Strand: Direct

Name: frr

Synonym: Chy400_3849

Alternate gene names: 222527070

Gene position: 4794501-4795058 (Clockwise)

Preceding gene: 222527069

Following gene: 222527071

Centisome position: 91.0

GC content: 52.33

Gene sequence:

>558_bases
ATGCTGAACGATGTAATCTCTGAATATGAGGCGCACCTGAAAAAGGCCACTGAAGCATTGCGACATCACCTGGCATCGAT
TCGCACTGGCCGCGCCTCGTCGGCGCTGGTTGAGCATCTTCACGTTGAAGCGTATGGTATGACCATGCCGCTCAATCAAC
TGGCCAACATCAGTGTGCCTGAGCCACGTCTGATTGTGATTCAGCCTTACGATGCCAATATGATCAAGGCAATTGAAAAA
GCGATCCAGCAATCAGACCTTGGCTTGAACCCCAGCAACGATGGACGCGTGATCAGGCTGCCGGTGCCACCATTAACCGA
AGAGCGCCGCCGTGAGCTGGTAAAAATGGTGCGACACCGGGTCGAAGAGGTGAAGATTTCAGTCCGTAATCAACGCCGCG
ATGCCATTGATGATCTGAAGAAGCTGGAAGCTGAAAAGCTGATCAGTGAAGATGAGCTACATCGTGGTCAGGAACGCATC
CAACAGTTGACTGATCGCTGCACCCGTGAGCTTGACCAGATCGGTGCGGAAAAAGAGGCAGAAGTGATGGCAGTTTAG

Upstream 100 bases:

>100_bases
CAATTATCGTGTTCAATGCGCTTGAACCCGGTACTATCGAGCGGATTGTGATGGGTGAACATGTCGGGACGCTTGTGAGT
AATCAGCGAGGAGGCGCGTA

Downstream 100 bases:

>100_bases
CCATCACTGAGAGGCACTGTCGTATGAGCGAGGATAATGTACTGGCCGGCGTAGCTATTCCGCAACATATTGCGGTCATT
ATGGATGGCAATGGACGTTG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MLNDVISEYEAHLKKATEALRHHLASIRTGRASSALVEHLHVEAYGMTMPLNQLANISVPEPRLIVIQPYDANMIKAIEK
AIQQSDLGLNPSNDGRVIRLPVPPLTEERRRELVKMVRHRVEEVKISVRNQRRDAIDDLKKLEAEKLISEDELHRGQERI
QQLTDRCTRELDQIGAEKEAEVMAV

Sequences:

>Translated_185_residues
MLNDVISEYEAHLKKATEALRHHLASIRTGRASSALVEHLHVEAYGMTMPLNQLANISVPEPRLIVIQPYDANMIKAIEK
AIQQSDLGLNPSNDGRVIRLPVPPLTEERRRELVKMVRHRVEEVKISVRNQRRDAIDDLKKLEAEKLISEDELHRGQERI
QQLTDRCTRELDQIGAEKEAEVMAV
>Mature_185_residues
MLNDVISEYEAHLKKATEALRHHLASIRTGRASSALVEHLHVEAYGMTMPLNQLANISVPEPRLIVIQPYDANMIKAIEK
AIQQSDLGLNPSNDGRVIRLPVPPLTEERRRELVKMVRHRVEEVKISVRNQRRDAIDDLKKLEAEKLISEDELHRGQERI
QQLTDRCTRELDQIGAEKEAEVMAV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=188, Percent_Identity=30.3191489361702, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI291042689, Length=158, Percent_Identity=33.5443037974684, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=45.9016393442623, Blast_Score=169, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24661488, Length=180, Percent_Identity=25, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_CHLAA (A9WAG2)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001637141.1
- ProteinModelPortal:   A9WAG2
- SMR:   A9WAG2
- GeneID:   5825374
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_3568
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21148; Mature: 21148

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNDVISEYEAHLKKATEALRHHLASIRTGRASSALVEHLHVEAYGMTMPLNQLANISVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCC
EPRLIVIQPYDANMIKAIEKAIQQSDLGLNPSNDGRVIRLPVPPLTEERRRELVKMVRHR
CCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
VEEVKISVRNQRRDAIDDLKKLEAEKLISEDELHRGQERIQQLTDRCTRELDQIGAEKEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EVMAV
HHCCC
>Mature Secondary Structure
MLNDVISEYEAHLKKATEALRHHLASIRTGRASSALVEHLHVEAYGMTMPLNQLANISVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCC
EPRLIVIQPYDANMIKAIEKAIQQSDLGLNPSNDGRVIRLPVPPLTEERRRELVKMVRHR
CCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
VEEVKISVRNQRRDAIDDLKKLEAEKLISEDELHRGQERIQQLTDRCTRELDQIGAEKEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EVMAV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA