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The map label for this gene is pyrH [H]

Identifier: 222527069

GI number: 222527069

Start: 4793767

End: 4794501

Strand: Direct

Name: pyrH [H]

Synonym: Chy400_3848

Alternate gene names: 222527069

Gene position: 4793767-4794501 (Clockwise)

Preceding gene: 222527068

Following gene: 222527070

Centisome position: 90.98

GC content: 54.42

Gene sequence:

>735_bases
ATGCAGCAGCCAAAATATCGCCGGATTTTAATCAAACTCAGCGGTGAACAGATCAAAGGCAACGATGGCGAGGTTATCAG
TTACGATATGCTTGACTTCCTCGCCCAGGAGATTGGTCGCGTTCATCGCCACGGTGTAGAAGTAGCCGTAGTTGTCGGTG
GTGGCAATATCTGGCGTGGTCATCGAGCCATTGAGCGCGGGATGGATGCCGCCCAATCGCACTACATGGGCATGCTGGCC
ACGATTATTAATGCTCTGGCCATGCAAGATGCCCTCGAACGCCATGGCCTCGACACGCGCGCAATGACTGCTATTAAGAT
GGATGAGGTGGCTGAGCCGTATATCCGCCGGCGGGCGACCCACCATCTGGAAAAAGGGCGCGTTATCATTCTGGCCGCCG
GTACCGGCAACCCCTATTTCACGACCGACTCGGCAGCCGCTCTGCGCGCAGCCGAAATTCACGCTGAAGTCATCCTGATG
GCAAAAAATGGTGTTGATGGCGTCTACGATGATGATCCCCGTCGCAATCCGGCAGCCACCCGCTTCGATCATATCCACTA
CCTCGAAGCTCTGAATCGTGGGCTGACGGTTATGGATAGTACGGCATTGACCTTCTGCATGGACAATAATCTGCCAATTA
TCGTGTTCAATGCGCTTGAACCCGGTACTATCGAGCGGATTGTGATGGGTGAACATGTCGGGACGCTTGTGAGTAATCAG
CGAGGAGGCGCGTAA

Upstream 100 bases:

>100_bases
GTTTATCCGCTACGAGGTTGGGGCATAAGAATCAGATGAGCCGGGCAGTTGCGGGACAACACCAGCATTGCCCGGCTCGT
TGCTACCTGCGAGTTGTTCC

Downstream 100 bases:

>100_bases
TGCTGAACGATGTAATCTCTGAATATGAGGCGCACCTGAAAAAGGCCACTGAAGCATTGCGACATCACCTGGCATCGATT
CGCACTGGCCGCGCCTCGTC

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MQQPKYRRILIKLSGEQIKGNDGEVISYDMLDFLAQEIGRVHRHGVEVAVVVGGGNIWRGHRAIERGMDAAQSHYMGMLA
TIINALAMQDALERHGLDTRAMTAIKMDEVAEPYIRRRATHHLEKGRVIILAAGTGNPYFTTDSAAALRAAEIHAEVILM
AKNGVDGVYDDDPRRNPAATRFDHIHYLEALNRGLTVMDSTALTFCMDNNLPIIVFNALEPGTIERIVMGEHVGTLVSNQ
RGGA

Sequences:

>Translated_244_residues
MQQPKYRRILIKLSGEQIKGNDGEVISYDMLDFLAQEIGRVHRHGVEVAVVVGGGNIWRGHRAIERGMDAAQSHYMGMLA
TIINALAMQDALERHGLDTRAMTAIKMDEVAEPYIRRRATHHLEKGRVIILAAGTGNPYFTTDSAAALRAAEIHAEVILM
AKNGVDGVYDDDPRRNPAATRFDHIHYLEALNRGLTVMDSTALTFCMDNNLPIIVFNALEPGTIERIVMGEHVGTLVSNQ
RGGA
>Mature_244_residues
MQQPKYRRILIKLSGEQIKGNDGEVISYDMLDFLAQEIGRVHRHGVEVAVVVGGGNIWRGHRAIERGMDAAQSHYMGMLA
TIINALAMQDALERHGLDTRAMTAIKMDEVAEPYIRRRATHHLEKGRVIILAAGTGNPYFTTDSAAALRAAEIHAEVILM
AKNGVDGVYDDDPRRNPAATRFDHIHYLEALNRGLTVMDSTALTFCMDNNLPIIVFNALEPGTIERIVMGEHVGTLVSNQ
RGGA

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=236, Percent_Identity=47.8813559322034, Blast_Score=222, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26894; Mature: 26894

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQPKYRRILIKLSGEQIKGNDGEVISYDMLDFLAQEIGRVHRHGVEVAVVVGGGNIWRG
CCCCCCEEEEEEECCCEECCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEHH
HRAIERGMDAAQSHYMGMLATIINALAMQDALERHGLDTRAMTAIKMDEVAEPYIRRRAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
HHLEKGRVIILAAGTGNPYFTTDSAAALRAAEIHAEVILMAKNGVDGVYDDDPRRNPAAT
HHHCCCCEEEEEECCCCCEEECCCHHHHHHHHEEEEEEEEEECCCCCCCCCCCCCCCCCH
RFDHIHYLEALNRGLTVMDSTALTFCMDNNLPIIVFNALEPGTIERIVMGEHVGTLVSNQ
HHHHHHHHHHHHCCCEEEECCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCC
RGGA
CCCC
>Mature Secondary Structure
MQQPKYRRILIKLSGEQIKGNDGEVISYDMLDFLAQEIGRVHRHGVEVAVVVGGGNIWRG
CCCCCCEEEEEEECCCEECCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEHH
HRAIERGMDAAQSHYMGMLATIINALAMQDALERHGLDTRAMTAIKMDEVAEPYIRRRAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
HHLEKGRVIILAAGTGNPYFTTDSAAALRAAEIHAEVILMAKNGVDGVYDDDPRRNPAAT
HHHCCCCEEEEEECCCCCEEECCCHHHHHHHHEEEEEEEEEECCCCCCCCCCCCCCCCCH
RFDHIHYLEALNRGLTVMDSTALTFCMDNNLPIIVFNALEPGTIERIVMGEHVGTLVSNQ
HHHHHHHHHHHHCCCEEEECCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCC
RGGA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA