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The map label for this gene is rsbRA [H]

Identifier: 222527043

GI number: 222527043

Start: 4762861

End: 4763955

Strand: Direct

Name: rsbRA [H]

Synonym: Chy400_3822

Alternate gene names: 222527043

Gene position: 4762861-4763955 (Clockwise)

Preceding gene: 222527042

Following gene: 222527045

Centisome position: 90.39

GC content: 55.8

Gene sequence:

>1095_bases
ATGCGAGCATTTACCACCTGGTTGTTTCAGATTCAGACCACTGATGAAGACGATCTCCGTCGCGGCCGCACCAACATTAT
CGTTTCACTGGTCATGATCATATTGGCAATACTGGCGATTCCTATCAGTTTTCTCGCTGAAAACAACCCCACCAGCGGCA
TCACCATAATCTCTGTAGGTATTATTGCTTACACCGTTTCCATAGCTGTTACGAAGGCTGGCCGGGTGAATATTGGTGGC
CTCATTCTGATCAGCTTTGTTACCCTACCAATACTGACACCGATTGTCGCCCAAACCTCACCAACCAGCCCCTTTACGTC
GCCTTTCTACCTCATTTTGTCTACGTTAGTGGCCGGATTAACCTTGCGACCGATCCTGACCTGGGCAGTATTGATCATCA
ATCTGGTCGGTCTGTTTGTTGCCTGGAATATTGCCGGGATCAACCTTTTTGCCGATGCGCTGGGAACCTCGCTCGGTGCG
GCTGCCATCTTCCTACAGATTGGTACAGCGCTCTTCACGTTTGTCGGCGGGCAGATTACCGCAACCGCCCTGCACGAGGC
ACGACAGCGCCGCGAAGAAGCCCGTCAGATCGCCGGTCAACTGGCAACCCTGAATGCCACCCTTGAAGCGCAGGTCGCCC
AGCGCACCGCCGCCTTACAACAAGCCCTGCACGAGCTTGAGCAGCGAGCTGCCGAACAGGCCCGGTTGCTGGCCGAAAAC
GAACAGCAACGGCAGGCCATCCGTGAATTGAGTGTACCGGTACTGCCCATCCGCGAGACGACGCTGGTGATGCCGCTGGT
TGGTGCCCTTGATACTGCCCGCCTGGCCGATATGCAACAGCAGGCCCTCGAACAGATTGCGCGTACCAATGCCCGTGACC
TGTTCATCGATGTAACCGGGGTACCGGTGATTGATACGCAGGTAGCCAAGGGGTTGATCCAGGTAGTCGAAGCTGCCCGC
TTGATGGGCACACGGGTCACCCTGGTCGGAATCCGACCAGAAGTCGCCCAAACCCTGGTCACGCTGGGCATTGACCTGCG
CTCAATTCGTACTTTTAGTACCTTGCAGGCTGCATTGGGGGAAGGGAGGAAGTAG

Upstream 100 bases:

>100_bases
AGATCCCGATTGCCTTATAACTTCTGCCCCATGTTGTGTCTGCAATGTATATAATCAAGACTGAAGAAAGCAATCACCCC
TTCTGATCATAGGAGAGGTC

Downstream 100 bases:

>100_bases
GAAATAGAAAATAGGGGATAGAAAAGTAGGAGATAGGGGTAAAGAATGTAGAGAATAGAGACGGAGAAAAGAGGAAGAAA
ATAGGAGATAGAAAAATAGG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MRAFTTWLFQIQTTDEDDLRRGRTNIIVSLVMIILAILAIPISFLAENNPTSGITIISVGIIAYTVSIAVTKAGRVNIGG
LILISFVTLPILTPIVAQTSPTSPFTSPFYLILSTLVAGLTLRPILTWAVLIINLVGLFVAWNIAGINLFADALGTSLGA
AAIFLQIGTALFTFVGGQITATALHEARQRREEARQIAGQLATLNATLEAQVAQRTAALQQALHELEQRAAEQARLLAEN
EQQRQAIRELSVPVLPIRETTLVMPLVGALDTARLADMQQQALEQIARTNARDLFIDVTGVPVIDTQVAKGLIQVVEAAR
LMGTRVTLVGIRPEVAQTLVTLGIDLRSIRTFSTLQAALGEGRK

Sequences:

>Translated_364_residues
MRAFTTWLFQIQTTDEDDLRRGRTNIIVSLVMIILAILAIPISFLAENNPTSGITIISVGIIAYTVSIAVTKAGRVNIGG
LILISFVTLPILTPIVAQTSPTSPFTSPFYLILSTLVAGLTLRPILTWAVLIINLVGLFVAWNIAGINLFADALGTSLGA
AAIFLQIGTALFTFVGGQITATALHEARQRREEARQIAGQLATLNATLEAQVAQRTAALQQALHELEQRAAEQARLLAEN
EQQRQAIRELSVPVLPIRETTLVMPLVGALDTARLADMQQQALEQIARTNARDLFIDVTGVPVIDTQVAKGLIQVVEAAR
LMGTRVTLVGIRPEVAQTLVTLGIDLRSIRTFSTLQAALGEGRK
>Mature_364_residues
MRAFTTWLFQIQTTDEDDLRRGRTNIIVSLVMIILAILAIPISFLAENNPTSGITIISVGIIAYTVSIAVTKAGRVNIGG
LILISFVTLPILTPIVAQTSPTSPFTSPFYLILSTLVAGLTLRPILTWAVLIINLVGLFVAWNIAGINLFADALGTSLGA
AAIFLQIGTALFTFVGGQITATALHEARQRREEARQIAGQLATLNATLEAQVAQRTAALQQALHELEQRAAEQARLLAEN
EQQRQAIRELSVPVLPIRETTLVMPLVGALDTARLADMQQQALEQIARTNARDLFIDVTGVPVIDTQVAKGLIQVVEAAR
LMGTRVTLVGIRPEVAQTLVTLGIDLRSIRTFSTLQAALGEGRK

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 39223; Mature: 39223

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFTTWLFQIQTTDEDDLRRGRTNIIVSLVMIILAILAIPISFLAENNPTSGITIISVG
CCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHH
IIAYTVSIAVTKAGRVNIGGLILISFVTLPILTPIVAQTSPTSPFTSPFYLILSTLVAGL
HHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
TLRPILTWAVLIINLVGLFVAWNIAGINLFADALGTSLGAAAIFLQIGTALFTFVGGQIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ATALHEARQRREEARQIAGQLATLNATLEAQVAQRTAALQQALHELEQRAAEQARLLAEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EQQRQAIRELSVPVLPIRETTLVMPLVGALDTARLADMQQQALEQIARTNARDLFIDVTG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
VPVIDTQVAKGLIQVVEAARLMGTRVTLVGIRPEVAQTLVTLGIDLRSIRTFSTLQAALG
CCEEHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHC
EGRK
CCCC
>Mature Secondary Structure
MRAFTTWLFQIQTTDEDDLRRGRTNIIVSLVMIILAILAIPISFLAENNPTSGITIISVG
CCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHH
IIAYTVSIAVTKAGRVNIGGLILISFVTLPILTPIVAQTSPTSPFTSPFYLILSTLVAGL
HHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
TLRPILTWAVLIINLVGLFVAWNIAGINLFADALGTSLGAAAIFLQIGTALFTFVGGQIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ATALHEARQRREEARQIAGQLATLNATLEAQVAQRTAALQQALHELEQRAAEQARLLAEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EQQRQAIRELSVPVLPIRETTLVMPLVGALDTARLADMQQQALEQIARTNARDLFIDVTG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
VPVIDTQVAKGLIQVVEAARLMGTRVTLVGIRPEVAQTLVTLGIDLRSIRTFSTLQAALG
CCEEHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHC
EGRK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]