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The map label for this gene is rsbRA [H]

Identifier: 222527042

GI number: 222527042

Start: 4761640

End: 4762752

Strand: Direct

Name: rsbRA [H]

Synonym: Chy400_3821

Alternate gene names: 222527042

Gene position: 4761640-4762752 (Clockwise)

Preceding gene: 222527041

Following gene: 222527043

Centisome position: 90.37

GC content: 54.09

Gene sequence:

>1113_bases
ATGCGCGGACTCGTACCATGGCTATTACACATCCCCAACGTTGATGAAGATGAGCAGCGGCGTGGGCAGGTGATTATAGT
GCTGGCATTACTCATAAATATCATCACCATATTATCAACACCGCTGGTATTTATCGTCACCCCACAATCGGCGTTACCGC
TCTTATTCATCAATATAGCCGGATTCGTTATCTATACCGCCGTTATCGTTCTCAGCAGAATCGGTCAAGTCTACTGGAGT
GGTGCGCTTTTTGTTATTACCATTACCAGTCTGATTCTTACAATCCCCTTTGGCATCCAAACAGACCGAATCACTTCTTA
TACTTCCCCCTTCTTTCTCATTTTTACACTTCTCGTTGCCGGAATGGTATTACGACCGATCTGGGTCTGGGCGGTGCTGA
TCTTCAACGTAAGTGGTCTTCTGGTTAGCTGGTGGCTGGCTGGAATACCATTATTTAGTGGTGAGCTTGAACAAACACTT
CAGACTGCGGCCATCTTCCTGCAGATTGGTACAGCACTCTTCACGTTTGTCGGTGGGCAGATTACCGCAACCGCCCTGCA
CGAGGCACGACAGCGCCGCGAAGAAGCCCGTCAGATCGCCGGTCAACTGGCAACCCTGAATGCCACCCTTGAAGCGCAGG
TCGCCCAGCGCACCGCCGCCTTACAACAGGCCTTGTACGAACTTGAGCAGCGGGCTGCTGAACAGGCCCGGTTGCTGGCC
GAAAACGAACAGCAACGGCAGGCCATCCGTGAATTGAGTGTACCGGTACTGCCCATCCGCGAGACAACGCTGGTGATGCC
GCTGGTTGGTGCCCTCGATACTGCCCGCCTGGCCGATATGCAACAGCAGGCCCTCGAACAGATTGCCCGTGCTAATGCCC
GTGACCTGTTCATCGATGTAACCGGGGTACCGGTGATTGATACGCAGGTAGCCAAGGGGTTGATCCAGGTGGTCGAAGCT
GCCCGCTTGATGGGCACACGGGTCACCCTGGTCGGCATTCGCCCGGAAGTCGCCCAAACCCTGGTCACGCTGGGTATTGA
CCTGCACTCAATTCGCACTTTTAGTACCTTGCAGGCTGCATTGAGGAGTGAACGACAGGCATCCGGGCAGTGA

Upstream 100 bases:

>100_bases
CCTGAAAACGGTTGGCAATGAATTGAGATAACTTCTGGTAGATGCTGTTTGAAACAGATTCTAGTGGGTTTAGAACGGAA
ACCAGGCGGAGGACGAAATT

Downstream 100 bases:

>100_bases
CGCAAAAAAGATCCCGATTGCCTTATAACTTCTGCCCCATGTTGTGTCTGCAATGTATATAATCAAGACTGAAGAAAGCA
ATCACCCCTTCTGATCATAG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MRGLVPWLLHIPNVDEDEQRRGQVIIVLALLINIITILSTPLVFIVTPQSALPLLFINIAGFVIYTAVIVLSRIGQVYWS
GALFVITITSLILTIPFGIQTDRITSYTSPFFLIFTLLVAGMVLRPIWVWAVLIFNVSGLLVSWWLAGIPLFSGELEQTL
QTAAIFLQIGTALFTFVGGQITATALHEARQRREEARQIAGQLATLNATLEAQVAQRTAALQQALYELEQRAAEQARLLA
ENEQQRQAIRELSVPVLPIRETTLVMPLVGALDTARLADMQQQALEQIARANARDLFIDVTGVPVIDTQVAKGLIQVVEA
ARLMGTRVTLVGIRPEVAQTLVTLGIDLHSIRTFSTLQAALRSERQASGQ

Sequences:

>Translated_370_residues
MRGLVPWLLHIPNVDEDEQRRGQVIIVLALLINIITILSTPLVFIVTPQSALPLLFINIAGFVIYTAVIVLSRIGQVYWS
GALFVITITSLILTIPFGIQTDRITSYTSPFFLIFTLLVAGMVLRPIWVWAVLIFNVSGLLVSWWLAGIPLFSGELEQTL
QTAAIFLQIGTALFTFVGGQITATALHEARQRREEARQIAGQLATLNATLEAQVAQRTAALQQALYELEQRAAEQARLLA
ENEQQRQAIRELSVPVLPIRETTLVMPLVGALDTARLADMQQQALEQIARANARDLFIDVTGVPVIDTQVAKGLIQVVEA
ARLMGTRVTLVGIRPEVAQTLVTLGIDLHSIRTFSTLQAALRSERQASGQ
>Mature_370_residues
MRGLVPWLLHIPNVDEDEQRRGQVIIVLALLINIITILSTPLVFIVTPQSALPLLFINIAGFVIYTAVIVLSRIGQVYWS
GALFVITITSLILTIPFGIQTDRITSYTSPFFLIFTLLVAGMVLRPIWVWAVLIFNVSGLLVSWWLAGIPLFSGELEQTL
QTAAIFLQIGTALFTFVGGQITATALHEARQRREEARQIAGQLATLNATLEAQVAQRTAALQQALYELEQRAAEQARLLA
ENEQQRQAIRELSVPVLPIRETTLVMPLVGALDTARLADMQQQALEQIARANARDLFIDVTGVPVIDTQVAKGLIQVVEA
ARLMGTRVTLVGIRPEVAQTLVTLGIDLHSIRTFSTLQAALRSERQASGQ

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 40682; Mature: 40682

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGLVPWLLHIPNVDEDEQRRGQVIIVLALLINIITILSTPLVFIVTPQSALPLLFINIA
CCCCCCHHHCCCCCCCCHHHCCCEEHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHH
GFVIYTAVIVLSRIGQVYWSGALFVITITSLILTIPFGIQTDRITSYTSPFFLIFTLLVA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
GMVLRPIWVWAVLIFNVSGLLVSWWLAGIPLFSGELEQTLQTAAIFLQIGTALFTFVGGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
ITATALHEARQRREEARQIAGQLATLNATLEAQVAQRTAALQQALYELEQRAAEQARLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENEQQRQAIRELSVPVLPIRETTLVMPLVGALDTARLADMQQQALEQIARANARDLFIDV
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
TGVPVIDTQVAKGLIQVVEAARLMGTRVTLVGIRPEVAQTLVTLGIDLHSIRTFSTLQAA
CCCCEEHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHH
LRSERQASGQ
HHHHHHCCCC
>Mature Secondary Structure
MRGLVPWLLHIPNVDEDEQRRGQVIIVLALLINIITILSTPLVFIVTPQSALPLLFINIA
CCCCCCHHHCCCCCCCCHHHCCCEEHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHH
GFVIYTAVIVLSRIGQVYWSGALFVITITSLILTIPFGIQTDRITSYTSPFFLIFTLLVA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
GMVLRPIWVWAVLIFNVSGLLVSWWLAGIPLFSGELEQTLQTAAIFLQIGTALFTFVGGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
ITATALHEARQRREEARQIAGQLATLNATLEAQVAQRTAALQQALYELEQRAAEQARLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENEQQRQAIRELSVPVLPIRETTLVMPLVGALDTARLADMQQQALEQIARANARDLFIDV
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
TGVPVIDTQVAKGLIQVVEAARLMGTRVTLVGIRPEVAQTLVTLGIDLHSIRTFSTLQAA
CCCCEEHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHH
LRSERQASGQ
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]