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The map label for this gene is metX [H]

Identifier: 222526963

GI number: 222526963

Start: 4663221

End: 4664357

Strand: Direct

Name: metX [H]

Synonym: Chy400_3741

Alternate gene names: 222526963

Gene position: 4663221-4664357 (Clockwise)

Preceding gene: 222526962

Following gene: 222526964

Centisome position: 88.5

GC content: 58.84

Gene sequence:

>1137_bases
ATGGAAGCAATTGTGCAGGCGCCAACCCCAGAGGGGGTTGGCATTGTGCGTACTCAACGGATGCATTGGACAACCCCCCT
GACCCTTACGAGCGGAGCGACGTTAGGTCCGATCACTCTGGCGTATGAAACCTACGGTGAACTGGCTCCGGATCGCTCGA
ATGCCATCTTGATTCTGCACGCTCTGTCTGGCGATGCCCACGCTGCCGGGTTTCACAGTCCAACCGACCGCAAACCCGGC
TGGTGGGACGCAATGATCGGGCCGGGTCGTCCGTTTGACACCAATCGTTACTTCGTGATCTGCTCAAATGTGATCGGCGG
CTGCCGTGGCTCAACCGGCCCGTCAAGTCCACACCCGTCTGATGGACGACCTTACGGTTCACGCTTTCCCCTTATCACCA
TTGAAGATATGGTGCATGCGCAACAGCGTCTGATCGATGCGCTGGGCATTGATACCCTGCTTGCCGTGGCGGGTGGCTCG
ATGGGTGGATTTCAGGCACTGGCCTGGACAGTAGAGTATCCGCAACGGGTGCGTGGCGCCATCCTGCTGGCTACCAGTGC
CCGCTCTAGCCCCCAGACTGTGGCCTGGAACTATATCGGTCGGCGGGCAATTATGGCCGATCCGCGCTGGCGAGGCGGTG
ATTACTACGATAGCGATGCGCCACGTGATGGGCTGGCAGTAGCCCGCATGCTCGGTCACATCACCTATCTGTGCGAAGAA
AAACTGGAACAGCGGTTTGGCCGTCGGGTTGATGGTGATGCGCTCGATTTAGGGCCACGGTTTGCTATCGAACACTACCT
CGAACATCAGGCGGCGCGCTTCAACGACCGCTTCGATGCCAACTCGTACCTGGTGATCACGCGGGCGATGGACAACTGGG
ATCTGACAGCACGGTATGGATCGCTGACAGCCGCCTTTGATCTGACCCGTGCCCGTTTTCTGGCCCTGGCGTACAGCAGC
GATTGGCTCTACCCACCGGCAGAAACGTATCAGATGGCGGCAGCCGCGCAAGCTGCCGGTCGTTCATTCACAACCCATCT
GATTACCACCGATGCCGGGCATGACGCATTCCTGACCGATGTCGCAGCGCAGAGCGAGCTGATCCGCGATTTTCTGAACA
GACTGATGACAGAATAG

Upstream 100 bases:

>100_bases
TCTTGATCATGCCCTGGCAGGAACCCCATCATAGTGTTGGATCAGAGAGCAACGACAACGGCGTCGCTGCTCTCTGATAC
CGGCAAGGAGCAACGACAAT

Downstream 100 bases:

>100_bases
TATGGCGTATGGGTTGTTTTTTTAATAGTTTTTTTATGACTCATCCGGTTGCGCATGCACTGATCTACTACATATAATGT
ATAGGCGTCATCGGCACCGG

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MEAIVQAPTPEGVGIVRTQRMHWTTPLTLTSGATLGPITLAYETYGELAPDRSNAILILHALSGDAHAAGFHSPTDRKPG
WWDAMIGPGRPFDTNRYFVICSNVIGGCRGSTGPSSPHPSDGRPYGSRFPLITIEDMVHAQQRLIDALGIDTLLAVAGGS
MGGFQALAWTVEYPQRVRGAILLATSARSSPQTVAWNYIGRRAIMADPRWRGGDYYDSDAPRDGLAVARMLGHITYLCEE
KLEQRFGRRVDGDALDLGPRFAIEHYLEHQAARFNDRFDANSYLVITRAMDNWDLTARYGSLTAAFDLTRARFLALAYSS
DWLYPPAETYQMAAAAQAAGRSFTTHLITTDAGHDAFLTDVAAQSELIRDFLNRLMTE

Sequences:

>Translated_378_residues
MEAIVQAPTPEGVGIVRTQRMHWTTPLTLTSGATLGPITLAYETYGELAPDRSNAILILHALSGDAHAAGFHSPTDRKPG
WWDAMIGPGRPFDTNRYFVICSNVIGGCRGSTGPSSPHPSDGRPYGSRFPLITIEDMVHAQQRLIDALGIDTLLAVAGGS
MGGFQALAWTVEYPQRVRGAILLATSARSSPQTVAWNYIGRRAIMADPRWRGGDYYDSDAPRDGLAVARMLGHITYLCEE
KLEQRFGRRVDGDALDLGPRFAIEHYLEHQAARFNDRFDANSYLVITRAMDNWDLTARYGSLTAAFDLTRARFLALAYSS
DWLYPPAETYQMAAAAQAAGRSFTTHLITTDAGHDAFLTDVAAQSELIRDFLNRLMTE
>Mature_378_residues
MEAIVQAPTPEGVGIVRTQRMHWTTPLTLTSGATLGPITLAYETYGELAPDRSNAILILHALSGDAHAAGFHSPTDRKPG
WWDAMIGPGRPFDTNRYFVICSNVIGGCRGSTGPSSPHPSDGRPYGSRFPLITIEDMVHAQQRLIDALGIDTLLAVAGGS
MGGFQALAWTVEYPQRVRGAILLATSARSSPQTVAWNYIGRRAIMADPRWRGGDYYDSDAPRDGLAVARMLGHITYLCEE
KLEQRFGRRVDGDALDLGPRFAIEHYLEHQAARFNDRFDANSYLVITRAMDNWDLTARYGSLTAAFDLTRARFLALAYSS
DWLYPPAETYQMAAAAQAAGRSFTTHLITTDAGHDAFLTDVAAQSELIRDFLNRLMTE

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=238, Percent_Identity=35.2941176470588, Blast_Score=155, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR008220 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =2.3.1.31 [H]

Molecular weight: Translated: 41543; Mature: 41543

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAIVQAPTPEGVGIVRTQRMHWTTPLTLTSGATLGPITLAYETYGELAPDRSNAILILH
CCCCCCCCCCCCCEEEEECCEEECCCEEEECCCCCCCEEEEEHHHHCCCCCCCCEEEEEE
ALSGDAHAAGFHSPTDRKPGWWDAMIGPGRPFDTNRYFVICSNVIGGCRGSTGPSSPHPS
EECCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEEECCHHCCCCCCCCCCCCCCC
DGRPYGSRFPLITIEDMVHAQQRLIDALGIDTLLAVAGGSMGGFQALAWTVEYPQRVRGA
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHCCCE
ILLATSARSSPQTVAWNYIGRRAIMADPRWRGGDYYDSDAPRDGLAVARMLGHITYLCEE
EEEEECCCCCCCEEEEHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KLEQRFGRRVDGDALDLGPRFAIEHYLEHQAARFNDRFDANSYLVITRAMDNWDLTARYG
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEECC
SLTAAFDLTRARFLALAYSSDWLYPPAETYQMAAAAQAAGRSFTTHLITTDAGHDAFLTD
CEEHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHH
VAAQSELIRDFLNRLMTE
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEAIVQAPTPEGVGIVRTQRMHWTTPLTLTSGATLGPITLAYETYGELAPDRSNAILILH
CCCCCCCCCCCCCEEEEECCEEECCCEEEECCCCCCCEEEEEHHHHCCCCCCCCEEEEEE
ALSGDAHAAGFHSPTDRKPGWWDAMIGPGRPFDTNRYFVICSNVIGGCRGSTGPSSPHPS
EECCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEEECCHHCCCCCCCCCCCCCCC
DGRPYGSRFPLITIEDMVHAQQRLIDALGIDTLLAVAGGSMGGFQALAWTVEYPQRVRGA
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHCCCE
ILLATSARSSPQTVAWNYIGRRAIMADPRWRGGDYYDSDAPRDGLAVARMLGHITYLCEE
EEEEECCCCCCCEEEEHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KLEQRFGRRVDGDALDLGPRFAIEHYLEHQAARFNDRFDANSYLVITRAMDNWDLTARYG
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEECC
SLTAAFDLTRARFLALAYSSDWLYPPAETYQMAAAAQAAGRSFTTHLITTDAGHDAFLTD
CEEHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHH
VAAQSELIRDFLNRLMTE
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA