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The map label for this gene is baeS [H]

Identifier: 222526879

GI number: 222526879

Start: 4554499

End: 4555686

Strand: Direct

Name: baeS [H]

Synonym: Chy400_3656

Alternate gene names: 222526879

Gene position: 4554499-4555686 (Clockwise)

Preceding gene: 222526878

Following gene: 222526880

Centisome position: 86.44

GC content: 58.5

Gene sequence:

>1188_bases
ATGATGAAGTGGCTGCGGCAGCTCCGCTGGAAGCTATTCATTTCCCATCTGATTATCGTCTTGATGGCCTACGTCGTACT
GCTGGCCGCTGCCAATGTACTGGCAAGTCTGGGCTGGACTGGCTTTGCCCCGCTGACCCTTGGTGCCGCAGCAGCCGAAA
CTGGTCAGTTGCAGGCTGGCCTCACCACCGAGGCTGGCGAGTTGCAAGAGCAGTTTCAATCGGTGATTCAGCAGGCGCTG
CTGATCAGCGGTTTTGCCGCGCTGGCGGCAGCAGTGATTGTGAGCCTCTTCGTTTCGCGGCGGATTGTTGAACCGATTCA
AACGCTCTCGAATGTGAGCCGACGGCTGGCACAGGGGTTTTACCGCGAACGTACCAGCATTCATGCCGATGATGAGATTT
CTCAGTTAGCGCATAGTGTCAATCAACTGGCCGAAGCCCTCGATCAGACGGAGCGGCGTCGTCTGGCATTACTGGCCGAT
GTGACGCACGAGTTGCGTACCCCGCTGGCGACGATTGGCGGGTACATGGAAGGGTTGCTGGATGGGGTTGTATCGGCGAA
TCCGGCTACCTTCAATCTGATCTTGCGTGAAACCCGTCGCCTTCAGCGCCTGATCGAAGATTTAGAGTTGCTATCGCGGG
TTGAAGCCGGTCAGTTGCCGGTCGTCGCCCGGGCAATCGATCTCCTGCCGGTGCTGGAAGCACAGCTCGCGCAGTTTGAA
CCGCTCTTCAGCAGCAATCAGGTGACGTTGCAGCTCGATGCGCCCGCACAGTTGCCGCAAGTATGGGCCGATCCGGATCG
GGTGGCGCAGGTGCTGATCAATATCCTGGCCAATGCCTACCGCTATACACCGGCAGGAGGAACAGTAACAGTGCAGGTGA
CGACCGATGATCACGAGGTGCGGGTAGCAGTGATCGATACCGGGATCGGGATTGCCGCCGAGCATCTGCCTCACGTATTC
GAGCGCTTTTACCGGGTTGATAAATCACGTGCCCGCAACAGTGGTGGGAGCGGGATCGGACTGGCGATTGCCCGTCACCT
GATCTATGCTCAGGGTGGCGAGATTTGGGCGGAAAGCGATGGGATCGGGAAAGGCGCACGCTTCATCTTTACCCTACCGC
TGGCACCGCAGATGGCGTTCGTGCGCGTAGACCATCCCGTCACGGTTGAGGCAGTTGACACGCTATGA

Upstream 100 bases:

>100_bases
ATATCGGTACTCTGCGGCGCAAGCTCGATGATGATCATCACGGCACGCCTCTGGTGCAGACGGTTCGTGGCGTTGGTTAT
AAGTTTGTTGGTAGTACGCG

Downstream 100 bases:

>100_bases
GCGCGCAATTCTGGCTTGGTCTGTTTCAACTTTTTCTGGTCGTCGGTGGCGCGCTGGCCGTGTCACTTTTCATCATTGAT
CGGCTCTTCCCTCCGGTACG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MMKWLRQLRWKLFISHLIIVLMAYVVLLAAANVLASLGWTGFAPLTLGAAAAETGQLQAGLTTEAGELQEQFQSVIQQAL
LISGFAALAAAVIVSLFVSRRIVEPIQTLSNVSRRLAQGFYRERTSIHADDEISQLAHSVNQLAEALDQTERRRLALLAD
VTHELRTPLATIGGYMEGLLDGVVSANPATFNLILRETRRLQRLIEDLELLSRVEAGQLPVVARAIDLLPVLEAQLAQFE
PLFSSNQVTLQLDAPAQLPQVWADPDRVAQVLINILANAYRYTPAGGTVTVQVTTDDHEVRVAVIDTGIGIAAEHLPHVF
ERFYRVDKSRARNSGGSGIGLAIARHLIYAQGGEIWAESDGIGKGARFIFTLPLAPQMAFVRVDHPVTVEAVDTL

Sequences:

>Translated_395_residues
MMKWLRQLRWKLFISHLIIVLMAYVVLLAAANVLASLGWTGFAPLTLGAAAAETGQLQAGLTTEAGELQEQFQSVIQQAL
LISGFAALAAAVIVSLFVSRRIVEPIQTLSNVSRRLAQGFYRERTSIHADDEISQLAHSVNQLAEALDQTERRRLALLAD
VTHELRTPLATIGGYMEGLLDGVVSANPATFNLILRETRRLQRLIEDLELLSRVEAGQLPVVARAIDLLPVLEAQLAQFE
PLFSSNQVTLQLDAPAQLPQVWADPDRVAQVLINILANAYRYTPAGGTVTVQVTTDDHEVRVAVIDTGIGIAAEHLPHVF
ERFYRVDKSRARNSGGSGIGLAIARHLIYAQGGEIWAESDGIGKGARFIFTLPLAPQMAFVRVDHPVTVEAVDTL
>Mature_395_residues
MMKWLRQLRWKLFISHLIIVLMAYVVLLAAANVLASLGWTGFAPLTLGAAAAETGQLQAGLTTEAGELQEQFQSVIQQAL
LISGFAALAAAVIVSLFVSRRIVEPIQTLSNVSRRLAQGFYRERTSIHADDEISQLAHSVNQLAEALDQTERRRLALLAD
VTHELRTPLATIGGYMEGLLDGVVSANPATFNLILRETRRLQRLIEDLELLSRVEAGQLPVVARAIDLLPVLEAQLAQFE
PLFSSNQVTLQLDAPAQLPQVWADPDRVAQVLINILANAYRYTPAGGTVTVQVTTDDHEVRVAVIDTGIGIAAEHLPHVF
ERFYRVDKSRARNSGGSGIGLAIARHLIYAQGGEIWAESDGIGKGARFIFTLPLAPQMAFVRVDHPVTVEAVDTL

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=275, Percent_Identity=36.3636363636364, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1786783, Length=251, Percent_Identity=35.0597609561753, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1786600, Length=280, Percent_Identity=31.7857142857143, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=31.3492063492063, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787894, Length=291, Percent_Identity=29.553264604811, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790346, Length=274, Percent_Identity=30.6569343065693, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=30.4545454545455, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=31.5352697095436, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI87082128, Length=291, Percent_Identity=27.8350515463918, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789149, Length=356, Percent_Identity=24.1573033707865, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790861, Length=247, Percent_Identity=31.1740890688259, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788713, Length=249, Percent_Identity=28.1124497991968, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081816, Length=235, Percent_Identity=31.4893617021277, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786912, Length=261, Percent_Identity=29.8850574712644, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=28.9795918367347, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788279, Length=325, Percent_Identity=24, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790551, Length=295, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787374, Length=265, Percent_Identity=26.7924528301887, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1789403, Length=295, Percent_Identity=26.7796610169492, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789808, Length=252, Percent_Identity=25.7936507936508, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43110; Mature: 43110

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKWLRQLRWKLFISHLIIVLMAYVVLLAAANVLASLGWTGFAPLTLGAAAAETGQLQAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCC
LTTEAGELQEQFQSVIQQALLISGFAALAAAVIVSLFVSRRIVEPIQTLSNVSRRLAQGF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRERTSIHADDEISQLAHSVNQLAEALDQTERRRLALLADVTHELRTPLATIGGYMEGLL
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
DGVVSANPATFNLILRETRRLQRLIEDLELLSRVEAGQLPVVARAIDLLPVLEAQLAQFE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
PLFSSNQVTLQLDAPAQLPQVWADPDRVAQVLINILANAYRYTPAGGTVTVQVTTDDHEV
CCCCCCCEEEEECCCCCCCHHCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCEE
RVAVIDTGIGIAAEHLPHVFERFYRVDKSRARNSGGSGIGLAIARHLIYAQGGEIWAESD
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEECCC
GIGKGARFIFTLPLAPQMAFVRVDHPVTVEAVDTL
CCCCCCEEEEEECCCCCEEEEEECCCEEEEECCCC
>Mature Secondary Structure
MMKWLRQLRWKLFISHLIIVLMAYVVLLAAANVLASLGWTGFAPLTLGAAAAETGQLQAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCC
LTTEAGELQEQFQSVIQQALLISGFAALAAAVIVSLFVSRRIVEPIQTLSNVSRRLAQGF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRERTSIHADDEISQLAHSVNQLAEALDQTERRRLALLADVTHELRTPLATIGGYMEGLL
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
DGVVSANPATFNLILRETRRLQRLIEDLELLSRVEAGQLPVVARAIDLLPVLEAQLAQFE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
PLFSSNQVTLQLDAPAQLPQVWADPDRVAQVLINILANAYRYTPAGGTVTVQVTTDDHEV
CCCCCCCEEEEECCCCCCCHHCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCEE
RVAVIDTGIGIAAEHLPHVFERFYRVDKSRARNSGGSGIGLAIARHLIYAQGGEIWAESD
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEECCC
GIGKGARFIFTLPLAPQMAFVRVDHPVTVEAVDTL
CCCCCCEEEEEECCCCCEEEEEECCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]